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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE294562 Characterization of a panel of mouse primary cell lines from Myc-driven mammary gland tumours and lung metastasis derived from them April 14, 2026Contributors : Josep Tarrago-Celada ; Michael Kossifos ; Ersa Gjelaj ; Yulia Panina ; Tegan Gilmore ; Mariia YunevaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTriple negative breast cancer (TNBC) represents 15% of all breast cancer subtypes. It is the most aggressive type, with limited treatment options and is often […]
- GSE286266 Age influences CMV-specific NK and CD8 T cell memory fates (NK cells) April 14, 2026Contributors : Isaac J Jensen ; Donna L FarberSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Mus musculusCytomegalovirus (CMV) infection is ubiquitous; though often unnoticed in healthy adults it is a leading cause of neurodisability in neonates/ infants. NK and CD8 T cell cytolysis control CMV; yet their coordinate respon […]
- GSE300647 Ryder: Epigenome Normalization and Variable Feature Identification April 14, 2026Contributors : Yaqiang Cao ; Guangzhe Ge ; Keji ZhaoSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiens ; Mus musculusSequencing-based epigenomic profiling significantly advances our understanding of chromatin regulation, yet inherent technical variability complicates accurate cross-sample comparisons. We int […]
- GSE296450 Limited Immune Perturbations in Mice Exposed to Sustained Low-Dose Ionizing Radiation April 14, 2026Contributors : Bryan Marr ; Holly Laakso ; Melinda Blimkie ; Andrew Cao ; Seung-Hwan Lee ; Abrar Ul Haq KhanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe effects of high-dose ionizing radiation (HDIR) exposure on the immune system are largely understood with consensus, yet there remains a fragmented understanding […]
- GSE304750 Arid3b suppresses CD8+ T cell infiltration and function in microsatellite stable colorectal cancer via Runx3 [RNA-seq] April 14, 2026Contributors : Shuo Wang ; Sen Hou ; Ce Luo ; Yingjiang Ye ; Zexian Zeng ; Zhidong GaoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMicrosatellite stable/proficient mismatch repair (MSS/pMMR) colorectal cancer (CRC) is characterized by a cold tumor microenvironment, marked by sparse CD8⁺ T cell infiltration and resist […]
- GSE303138 HNRNPH controls alternative splicing cooperatively on a transcriptome-wide scale April 14, 2026Series Type : Other ; Expression profiling by high throughput sequencingOrganism : Homo sapiens ; synthetic constructThis SuperSeries is composed of the SubSeries listed below.
- GSE327576 Transcriptomic and Metabolic Basis of Volatile Compound Dynamics in Apricot Fermentation April 14, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Wickerhamomyces anomalusAroma is one of the most important qualities that defines the appeal and value of the fermented fruit products. This study provides the first integrative analysis of volatile compound dynamics and transcriptomic regulations during apricot fermentation by Wicker […]
- GSE328012 Inference of emergent spatio-temporal processes from single-cell sequencing reveals feedback between de novo DNA methylation and chromatin condensates [Bisulfite-Seq 2] April 14, 2026Contributors : Fabrizio Olmeda ; Tim Lohoff ; Ioannis Kafetzopoulos ; Stephen J Clark ; Laura Benson ; Fatima Santos ; Felix Krueger ; Simon Walker ; Wolf Reik ; Steffen RulandsSeries Type : Methylation profiling by high throughput sequencingOrganism : Mus musculusRecent breakthroughs in single-cell genomics allow probing molecular states of cells with unpre […]
- GSE327681 JMJD1C-mediated epigenetic control of autoimmunity and HIT antibody production [RNA-seq] April 14, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusHeparin-induced thrombocytopenia (HIT) is a common drug-induced immune disorder occurring in a subset of heparin-treated patients. Immune complexes comprising heparin, platelet factor 4 (PF4), and PF4/heparin-reactive antibodies are central to its pathogenesis. However, th […]
- GSE327577 Faecalibacterium prausnitzii EXL01 for the Maintenance of Steroid-induced Clinical Response or Remission in Patients with Crohn’s Disease: a first in human trial April 14, 2026Contributors : Perle Guarino-Vignon ; Edouard Louis ; Hang-Phuong Pham ; Giovanna Orianne ; Emma Tkacz ; Loic Brot ; Eolia Mazzetti ; Delphine Sedda ; Pauline Ruffié ; Nathalie Rolhion ; Geert D’Haens ; Benjamin Hadida ; Philippe Langella ; Harry SokolSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensA marked decrease in […]
- GSE327717 Association of serum uric acid with cardiovascular risk and exploratory analysis of circulating tsRNA biomarkers in gout patients April 14, 2026Contributors : Shaofan Zhang ; Huan Dong ; Ting Liu ; Youjun Xiao ; Hanshi Xu ; Hao Li ; Liuqin Liang ; Qian QiuSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensSreum from gout patients and healthy controls underwent high-throughput small-RNA sequencing to profile tRNA-derived small RNAs(tsRNAs) in gout.
- GSE327751 Defined cell culture medium contributes to transcriptional reprogramming to enhance membrane-associated mucin expression in human corneal epithelial cells April 14, 2026Contributors : Hsieh Hsiu-Hui ; Lin Chen-Hua ; Hung Kai-Feng ; Sun Yi-ChenSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThis study investigates the transcriptional mechanisms by which a defined culture condition enhances membrane-associated mucin expression in human corneal epithelial cells (HCECs). RNA sequencing was […]
- GSE328010 RNA sequencing of naïve, activated and HIV-1 infected CD4+ T cells April 14, 2026Contributors : Sean Paz ; Massimo CaputiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCD4+ T cells play a major role in immune function regulation. Naive CD4+ T cells undergo major transcriptional changes upon activation through simultaneous engagement of the T-cell receptor and co-stimulatory molecules (anti-CD3/anti […]
- GSE276024 Mitochondrial metabolism regulates the immunogenic responsiveness of dendritic cells [RNA-seq] April 14, 2026Contributors : Ignacio Heras-Murillo ; Stefanie K Wculek ; David SanchoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusActivation of dendritic cells (DCs) is linked to increased glycolysis. However, the role of the mitochondrial electron transport chain (ETC) in conventional DC subset function is poorly defined. Here, w […]
- GSE327567 Heat shock factor 5 is indispensable for pachynema progression and LINE1 silencing during spermatogenesis in mice [RNA-seq] April 14, 2026Contributors : Qi Sun ; Yuming Cao ; Zhiyi Chen ; Jin Shen ; Zejia Li ; Binyi Wang ; Muyang Cheng ; Jiemin Chen ; Weihao Gong ; Mengcheng Luo ; Yuanzhen Zhang ; Rong LiuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPachytene spermatocytes were isolated from adult wild-type and Hsf5 knockout mouse testes using STA-PUT […]