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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE294643 Modular neuroinflammatory network discovery from large-scale phenotypic screening in genetically heterogeneous mice [part6] April 11, 2026Contributors : Mitchell Rezzonico ; Christopher J Bohlen ; Lisa A Miosge ; Brad A FriedmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe central nervous system represents a uniquely immune-privileged environment, with inflammatory responses involving several resident CNS-specific cell types. While stereotyped cellu […]
- GSE294528 Modular neuroinflammatory network discovery from large-scale phenotypic screening in genetically heterogeneous mice [part4] April 11, 2026Contributors : Mitchell Rezzonico ; Christopher J Bohlen ; Lisa A Miosge ; Brad A FriedmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe central nervous system represents a uniquely immune-privileged environment, with inflammatory responses involving several resident CNS-specific cell types. While stereotyped cellu […]
- GSE294832 Modular neuroinflammatory network discovery from large-scale phenotypic screening in genetically heterogeneous mice [part10] April 11, 2026Contributors : Mitchell Rezzonico ; Christopher J Bohlen ; Lisa A Miosge ; Brad A FriedmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe central nervous system represents a uniquely immune-privileged environment, with inflammatory responses involving several resident CNS-specific cell types. While stereotyped cellu […]
- GSE294686 Modular neuroinflammatory network discovery from large-scale phenotypic screening in genetically heterogeneous mice [part8] April 11, 2026Contributors : Mitchell Rezzonico ; Christopher J Bohlen ; Lisa A Miosge ; Brad A FriedmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe central nervous system represents a uniquely immune-privileged environment, with inflammatory responses involving several resident CNS-specific cell types. While stereotyped cellu […]
- GSE294911 Modular neuroinflammatory network discovery from large-scale phenotypic screening in genetically heterogeneous mice [part14] April 11, 2026Contributors : Mitchell Rezzonico ; Christopher J Bohlen ; Lisa A Miosge ; Brad A FriedmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe central nervous system represents a uniquely immune-privileged environment, with inflammatory responses involving several resident CNS-specific cell types. While stereotyped cellu […]
- GSE294845 Modular neuroinflammatory network discovery from large-scale phenotypic screening in genetically heterogeneous mice [part12] April 11, 2026Contributors : Mitchell Rezzonico ; Christopher J Bohlen ; Lisa A Miosge ; Brad A FriedmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe central nervous system represents a uniquely immune-privileged environment, with inflammatory responses involving several resident CNS-specific cell types. While stereotyped cellu […]
- GSE307078 Dopaminergic neurons are vulnerable to dysregulation of YEATS2-dependent calcium homeostasis April 11, 2026Contributors : Luca Lo Piccolo ; Ranchana Yeewa ; Pitiporn Noisagul ; Arnaud Monteil ; Vorasuk Shotelersuk ; Salinee JantrapiromSeries Type : Expression profiling by high throughput sequencingOrganism : Drosophila melanogasterYEATS2, a chromatin-associated factor, is essential for maintaining dopaminergic (DA) synaptic integrity, but the underlying mechanism […]
- GSE327123 Genome-Wide Dual-Selection Unveils Novel Self-Cleaving Ribozymes in the Human Genome April 11, 2026Contributors : Zhe Zhang ; Jian Zhan ; Yaoqi ZhouSeries Type : OtherOrganism : Homo sapiensThe landscape of catalytic RNAs in complex eukaryotes remains poorly charted. Although self-cleaving ribozymes are widespread in microbial and viral genomes, their existence and functional roles in humans remain largely unknown. Here, we introduce a generalizable, geno […]
- GSE327031 Gene expression in whole seedlings (wild-type, nlp6nlp7-KO) April 11, 2026Contributors : Yasuhito Sakuraba ; Shuichi YanagisawaSeries Type : Expression profiling by arrayOrganism : Arabidopsis thalianaTo examine differential effect of the mutation of Arabidopsis NLP6 and NLP7 on the gene expressions, we performed microarray analysis using root tissue of seedlings of wild-type and nlp6nlp7 double mutant.
- GSE310210 Berry-derived gold nanoparticles induce integrated oxidative stress-mediated apoptosis, immune modulation, and transcriptomic remodeling in 4T1 triple-negative cancer cells April 11, 2026Contributors : Oladapo Fagbohun ; Adewale Oladipo ; Chengyu Gao ; Babatunde Olawoye ; Rachel Berry ; Jaylah Captain ; Olive Iragena ; Xavier McDougle ; Randy Harris ; Amanda Rollins ; Jitcy Joseph ; Olatomide Fadare ; Russell KincaidSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusComprehensive molecular and phenotypic c […]
- GSE327044 Lenvatinib exacerbates colitis by inhibiting intestinal vascular endothelial MAdCAM-1-mediated B cell trafficking April 11, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe use of lenvatinib (Lenv) in advanced hepatocellular carcinoma (HCC) patients is associated with a range of adverse events, including gastrointestinal toxicities, yet the underlying mechanisms remain poorly understood. Here, we demonstrated that Lenv exacerbated both ac […]
- GSE327105 Lenvatinib exacerbates colitis by inhibiting intestinal vascular endothelial MAdCAM-1-mediated B cell trafficking. April 11, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe use of lenvatinib (Lenv) in advanced hepatocellular carcinoma (HCC) patients is associated with a range of adverse events, including gastrointestinal toxicities, yet the underlying mechanisms remain poorly understood. Here, we demonstrated that Lenv exacerbated both ac […]
- GSE327117 Transcriptomic and Accessibilty characterization of Wild type mouse Embryonic Stem Cells (mESCs), β-actin Knock out mESC and upon rescue with a nuclear localization signal β-actin April 11, 2026Contributors : Nadine Hosny El Said ; Colin Campbell ; Amani Nuairi ; Sabrina Desbordes ; Piergiorgio PercipalleSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusPluripotency and lineage commitment in embryonic stem cells depend on coordinated regulation of chromatin architecture and extracellular matrix (EC […]
- GSE294446 Modular neuroinflammatory network discovery from large-scale phenotypic screening in genetically heterogeneous mice [part2] April 11, 2026Contributors : Mitchell Rezzonico ; Christopher J Bohlen ; Lisa A Miosge ; Brad A FriedmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe central nervous system represents a uniquely immune-privileged environment, with inflammatory responses involving several resident CNS-specific cell types. While stereotyped cellu […]
- GSE302307 PP2A Regulates Senescence and Immunogenicity in Medulloblastoma April 11, 2026Contributors : Winson Ho ; Isha Mondal ; Jingjing Liu ; Rayond Sun ; Jiyang Yu ; Rongze LuSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiens ; Mus musculusMedulloblastoma (MB) is the most common malignant pediatric brain tumor. Current treatments carry significant morbidity, and prognosis remains poor in subgroups with TP […]