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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE270757 CXCR4 influences PUFA desaturation and oxidative stress injury in experimental prostatitis mice by activating Fads2 via PPARγ June 24, 2026Contributors : Yi Zhang ; Rui Feng ; Haolin Li ; Weikang Wu ; Wenming Ma ; Xianguo Chen ; Jing Chen ; Chaozhao LiangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe aim of this study was to further understand the changes in mRNA expression in the prostate tissue of EAP mice after using LIT-927. After constructing the […]
- GSE293919 Longitudinal monitoring of cytoplasmic RBP-RNA interactions and transcriptome in living cells by engineered protein nanocages June 24, 2026Contributors : Lu-Feng Hu ; Gang Xie ; Yangming WangSeries Type : Expression profiling by high throughput sequencing ; Other ; Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiens ; Mus musculusMost existing RNA sequencing methods rely on cell lysis or fixation, limiting their use in longitudinal studies of the same cell population. […]
- GSE288438 Characterization of the effects of ISX9 treatment on RBPJ target genes. [RNA-Seq] June 24, 2026Contributors : Subhamita Day ; Friedrich Tobias ; Giaimo Benedetto DanieleSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe Notch signaling pathway regulates several processes including development and differentiation and its aberrant regulation leads to several diseases. The transciption factor RBPJ is the main media […]
- GSE302610 Genome-wide mapping of DNA G-quadruplexes in Trypanosoma brucei chromatin reveals enrichment in coding regions and transcription start sites [ChIP-seq] June 24, 2026Contributors : Ludovica Monti ; Genta Firth ; Joana R Correia Faria ; John M Kelly ; Gem Flint ; Silvia Galli ; Thomas E Maher ; Htay Mon Aye ; Marco Di AntonioSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Trypanosoma bruceiG-quadruplexes (G4s) are non-canonical DNA structures formed in guanine-rich sequences that a […]
- GSE300733 Burn injury triggers distinct transcriptomic profiles in adipose tissue of adult and aged mice June 24, 2026Contributors : Bhattachan Punit ; Vlavcheski Filip ; Wojtowicz-Piotrowski Stephanie ; Jeschke Marc GSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSevere burns are a major global health concern, and are associated with long-term physical and psychological impairments, multi-organ dysfunction, and substantial morbidity […]
- GSE319513 DNA-PKcs inhibitor KU-57788 synergizes with ferroptosis in anaplastic thyroid cancer cells June 24, 2026Contributors : Lingling Ding ; Guowan Zheng ; Chuanming ZhengSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensNext Generation Sequencing Facilitates Quantitative Analysis of 8505C cells treated with KU-57788 and DMSO
- GSE304981 Pioneer transcription factor TAL1 reshapes chromatin architecture to direct erythroid cell fate commitment [ATAC-Seq] June 24, 2026Contributors : Lixiang Chen ; Ying Cheng ; Lei Sun ; Hengchao Zhang ; Xiuyun WuSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensPioneer transcription factors critically regulate chromatin organization and hematopoietic cell lineage commitment. During erythropoiesis, hematopoietic stem cells undergo dynamic […]
- GSE335943 In vitro implantation model that recapitulates primary implantation events June 24, 2026Contributors : Matsu-ura Toru ; Pham Tam Thi ; Ikeda Yoshiki ; Yoshida Naoko ; Kobayashi Tetsuya ; Hashimoto Yoshiko ; Atsumi Naho ; Takeda Hiroyuki ; Kinoshita-Okabe Miki ; Takahashi Keiichi ; Okada Hidetaka ; Tsuta KojiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe established an in vitro implantation model (IVIM) […]
- GSE335942 Deformability screening identifies NUDT5 as a mediator of cellular mechanobiology June 24, 2026Contributors : Angelina Flores ; Jennifer Soto ; Amy RowatSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensHow cells deform, sense, and respond to mechanical cues drives physiological and disease processes ranging from development to cancer metastasis; however, unbiased approaches to identify mechanical mediators are lac […]
- GSE335980 Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin-knockout and Supervillin-mutant Mice June 24, 2026Contributors : Tara C Smith ; Yanyi E Luo ; Elisabeth R Barton ; Elizabeth J LunaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil-Mut mice express the Svil-encoded N-terminus fused to the bgal-neo gene trap tag and lack t […]
- GSE335950 Bulk RNA-seq of EO771 breast cancer cells with 3 conditions June 24, 2026Contributors : Yue Wu ; Elena Ghiban ; Jeremy BornigerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBulk RNA sequencing was performed to compare mRNA expression profiles across six experimental conditions: monoculture of EO771 breast cancer cells; conditioned medium from DRG neurons applied to EO771 cells; and direct […]
- GSE336012 Nicotine and tobacco smoke reshape neuronal signaling networks at a single-cell perspective June 24, 2026Contributors : Jian Jiang ; Anfu Hu ; Yixiao Jin ; Xia Li ; Guo-jun Zhou ; Yi Shen ; Chengyun Xu ; Xing Ji ; Ximei Wu ; Hong-Juan WangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusNicotine and cigarette smoke exposure significantly impact brain function, yet their distinct cellular and molecular mechanisms remain uncl […]
- GSE336192 Paired CRISPR screens to map gene regulation in cis and trans (RNA-seq) June 24, 2026Contributors : Xinhe Xue ; Xiao Wang ; Zoran Gajic ; Christina Caragine ; Mateusz Legut ; Mari Bell ; Wen-Wei Liang ; Conor Walker ; James Kim ; Rachel E Yan ; Gina I Hong ; Hans-Hermann Wessels ; Congyi Lu ; Neil Bapodra ; Gamze Gursoy ; Neville E SanjanaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensIn this study, we […]
- GSE336258 Myl1+ adipose progenitor cells (APCs) support brown adipose tissue (BAT) maintenance in adult mice June 24, 2026Contributors : Zan Huang ; Zengdi Zhang ; Hai-Bin RuanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe ontogeny of brown adipose tissue (BAT) begins during embryogenesis and continues into the postnatal period and throughout adulthood. Distinct populations of adipose progenitor cells (APCs) have been identified to su […]
- GSE235576 Transcriptome analysis of NECs derived from different hPSCs with different protocols June 24, 2026Contributors : Yeganeh Meghdad ; Guenther StefanSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo obtain neuroepithelial cells (NECs) for transplantation, we differentiated human embryonic stem cells (hESCs) using a 3-day or 12-day protocol and also human induced pluripotent stem cells (hiPSCs) using a 3-day protocol.T […]