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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE287347 MafB is a conserved transcriptional regulator of macrophage development and identity across tissues and species February 25, 2026Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiens ; Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE290387 RNA-sequencing from nasal curettes or swabs collected from young children aged 1-5 February 25, 2026Contributor : Simon JochemsSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThere is a paucity of data on how the mucosal immune system changes with age. Moreover, the link between nasal presence of bacteria and viruses with the immune system in young children is still poorly understood. To address these questions we col […]
- GSE290213 A single cell transcriptional profile of benign prostatic hyperplasia February 25, 2026Contributors : Rei Unno ; Jon Akutagawa ; Hanbing Song ; Keliana Hui ; Yih-an Chen ; Julia Pham ; Jean Lee ; Heiko Yang ; Franklin Huang ; Thomas ChiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensBenign prostatic hyperplasia (BPH) is characterized by excessive cell proliferation and inflammation and affects most aging […]
- GSE294177 Physical Crowding in 3D Niche Regulates NSCs of Cell Junction and Differentiation February 25, 2026Contributors : Yuyun Liang ; Xiaonan Wang ; Chaoyong He ; Zhiyan Wu ; Jing Yang ; Ziyan Chen ; Hexu Zhang ; Cheng Zhao ; Liyang ShiSeries Type : Expression profiling by high throughput sequencingOrganism : Rattus norvegicusNeural stem cells (NSCs) maintain central nervous system (CNS) homeostasis through self-renewal and differentiation into neurons and glia […]
- GSE290421 Docosahexaenoic Acid Protects the Lungs from Ozone-Induce Inflammation Via its Oxylipins February 25, 2026Contributors : Michael J Yaeger ; Tyson Ngatikaura ; Natali Zecchino ; Hannah B Lovins ; Evangeline Schott ; Samuel J Cochran ; Grace Hutton ; Jessica L Ray ; Brett Saunders ; Laura Leuenberger ; Brita Kilburg-Basnyat ; Rafia Virk ; Rachel V Duinen ; Xiaokui Mo ; Michael Armstrong ; Matthew I McFadden ; Jennifer I Fenton ; Nichole Reisdorph ; Adriana Forero […]
- GSE271953 Drugging the intrinsically disordered transactivation domain of androgen receptor [LNCaP] February 25, 2026Contributors : Jon K Obst ; Carmen A Banuelos ; Kunzhong Jian ; Amy H Tien ; Jun Wang ; Nasrin R Mawji ; Teresa Tam ; Raymond J Andersen ; Marianne D SadarSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensAndrogen receptor (AR) is a therapuetic target for prostate cancer. Despite therapuetic approaches against its ligand- […]
- GSE320216 Genome reorganization and its functional impact during breast cancer progression [RNA-Seq] February 25, 2026Contributors : Kathleen S Reed ; Tom Misteli ; Andrew Fritz ; Haley Greenyer ; Seth Frietze ; Janet Stein ; Gary SteinSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo explore how chromatin structure and epigenetic parameters of genome architecture changes during cancer progression at a fine scale and genome-wide, we g […]
- GSE315959 Dissecting FOXA1 pioneering function by acute pharmacological degradation. February 25, 2026Contributors : Lauren M Hargis ; Paige A Barta ; Yuxiang Zhang ; Rachel E Hayward ; Benjamin F Cravatt ; Michael A ErbSeries Type : Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism : Homo sapiensPioneer factors control transcription by opening chromatin, but a lack of chemical tools […]
- GSE314820 Obeticholic acid accelerates portal vein embolization-induced liver hypertrophy in rabbits by improving bile salt homeostasis February 25, 2026Contributors : Xinwei Chang ; Pim B Olthof ; Han Jin ; Steven Chau ; Zita Soons ; Hans van Eijk ; Rowan van Golen ; Thomas van Gulik ; Michal Heger ; Peter L Jansen ; Steven Olde Damink ; Frank G SchaapSeries Type : Expression profiling by high throughput sequencingOrganism : Oryctolagus cuniculusPurpose: Obeticholic acid (OCA), an agonist of the bile salt-a […]
- GSE320076 Natural constitutive promoters from Actinoplanes siamensis TBRC 4237 enable high-level heterologous gene expression in Streptomyces coelicolor February 25, 2026Contributors : Suranan Yoolong ; Wuttichai Mhuantong ; Jindaporn Kongsee ; Kitlada Srichomthong ; Chayaphat Wongsombat ; Pattanop Kanokratana ; Chanwit Suriyachadkun ; Vanicha Vichai ; Aiyada AroonsriSeries Type : Expression profiling by high throughput sequencingOrganism : Actinoplanes siamensisActivation of cryptic biosynthetic gene clusters (BGCs) in acti […]
- GSE319407 Teratoma formation by Safe and Allo-Accepted Pluripotent Cells February 25, 2026Contributors : Vivian Tam ; Danny ChanSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensPluripotent stem cells are a promising alternative in cell and tissue transplantation as they have the potential to be differentiated into different cell types to treat various diseases. However, two major challenges have hindered thei […]
- GSE320120 Thiolutin Extends Replicative Lifespan by Rewiring Yeast Transcription and Metabolism February 25, 2026Contributors : Mateusz Mołoń ; Patrycja Kielar ; Zofia Kobylińska ; Agnieszka Mołoń ; Jarosław Winiarski ; Monika Kula-Maximenko ; Sabina GaliniakSeries Type : Expression profiling by high throughput sequencingOrganism : Saccharomyces cerevisiaeThis study examines the global transcriptomic response of Saccharomyces cerevisiae strain BY4741 to short-term expo […]
- GSE320155 scRNA‑seq of human intra‑hepatic CD4⁺ T cells reveals unique Treg transcriptional identities and two steady‑state tissue‑adaptation programs across healthy and HCC liver samples February 25, 2026Contributors : Elena Perpiñán ; Nicolas Sompairac ; Shahram Kordasti ; Alberto Sanchez-Fueyo ; Niloufar SafiniaSeries Type : Other ; Expression profiling by high throughput sequencingOrganism : Homo sapiensWe employed a single‑cell sequencing approach using the 10x Genomics platform, including scRNA‑seq, CITE‑seq, and paired TCR libraries, to investigate the […]
- GSE320215 Genome reorganization and its functional impact during breast cancer progression [ATAC-Seq] February 25, 2026Contributors : Kathleen S Reed ; Tom Misteli ; Andrew Fritz ; Haley Greenyer ; Seth Frietze ; Janet Stein ; Gary SteinSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensTo explore how chromatin structure and epigenetic parameters of genome architecture changes during cancer progression at a fine scale and gen […]
- GSE272963 Differential Expression of Mitochondrial Natural Antisense Transcripts in Clinical Samples of Plasmodium falciparum Across Multiple Disease Phenotypes February 25, 2026Contributors : Sukriti Gujarati ; Ashis DasSeries Type : Expression profiling by arrayOrganism : Plasmodium falciparumThe malaria parasite mitochondria are critical targets for antimalarial drugs, but emerging drug resistance against existing protein targets necessitates novel therapeutic approaches. Using custom-designed, multi-probe microarrays and pooled […]