Healthcare updates

Gene Expression Omnibus Announcements & Study Releases

Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.

• GSE232419 LINC01770 mediates nasopharyngeal cancer radiation resistance and renders tumor cell vulnerable to ferroptosis May 6, 2026
  Contributors : Qing Q Xu ; Xin Wen ; Xuan Li ; Lei ChenSeries Type : Expression profiling by high throughput sequencing ; Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensLong noncoding RNAs (lncRNAs) participate in regulation of various essential biological processes including cell proliferation, differentiation, apoptosis, migra […]
• GSE293758 Spatial and Functional Specialization of Human Splenic Innate Lymphoid Cells (CITE-seq] May 6, 2026
  Contributors : Sarah J Colpitts ; Sinthuja Jegatheeswaran ; Siavash Mashhouri ; Ash Hagerman ; Mahmoud El-Maklizi ; Humaira Murshed ; Martin L Mak ; Kyle T Reid ; Julia M Murphy ; Jessica A Mattews ; Clinton S Robbins ; Sarah Q CromeSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Homo sapiensTo date, the spatial and functio […]
• GSE266257 Effects of inorganic phosphate on stem cells isolated from human exfoliated deciduous teeth May 6, 2026
  Contributors : Ravipha Suwittayarak ; Nunthawan Nowwarote ; Chatvadee Kornsuthisopon ; Waleerat Sukarawan ; Brian L Foster ; Hiroshi Egusa ; Thanaphum OsathanonSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensAim: Calcium phosphate-based materials (CaP) are introduced as potential dental pulp capping materials for decidu […]
• GSE296448 Glycerol-3-Phosphate Dehydrogenase 1-Like serves as a tumor suppressor in colorectal cancer through ATF3-mediated ferroptosis May 6, 2026
  Contributors : Changjiang Yang ; Long Zhao ; Zihan Zhao ; Lin GanSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensColorectal cancer (CRC) continues to be a prevalent malignancy, posing a significant risk to human health. The involvement of Glycerol-3-phosphate dehydrogenase 1-like (GPD1L) in CRC development was suggested […]
• GSE293759 Spatial and Functional Specialization of Human Splenic Innate Lymphoid Cells [Xenium] May 6, 2026
  Contributors : Sarah J Colpitts ; Sinthuja Jegatheeswaran ; Siavash Mashhouri ; Ash Hagerman ; Mahmoud El-Maklizi ; Humaira Murshed ; Martin L Mak ; Kyle T Reid ; Julia M Murphy ; Jessica A Mathews ; Clinton S Robbins ; Sarah Q CromeSeries Type : OtherOrganism : Homo sapiensTo date, the spatial and functional characterization of human splenic innate lymphoid […]
• GSE298866 Transcriptomic Profiling of Neonatal Offspring Hearts from Gestational Diabetes Mellitus Rat Models May 6, 2026
  Contributors : Zemeng Xiao ; Jun Pu ; Xiyuan LuSeries Type : Expression profiling by high throughput sequencingOrganism : Rattus norvegicusMaternal diabetes during pregnancy has been associated with an increased risk of metabolic and cardiovascular disorders in the offspring. However, the underlying mechanisms by which intrauterine hyperglycemia impairs feta […]
• GSE296499 CK2α deletion in the hematopoietic compartment leads to mild alterations in terminally differentiated cells and expansion of stem cells May 6, 2026
  Contributors : Rajesh Rajaiah ; Muhammad Daniyal ; Marudhu Pandiyan Shanmugam ; Hannah Valensi ; Koby Duke ; Katie Mercer ; Morgann Klink ; Lanza Matthew ; Yasin Uzun ; Suming Huang ; Sinisa Dovat ; Chandrika Gowda BehuraSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusCasein Kinase II(CK2) is a ubiquitously present seri […]
• GSE301254 Single-nucleus profiling reveals a core disease signature and cell-type-specific vulnerabilities in early Rett syndrome May 6, 2026
  Contributor : Yan LiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusRett syndrome (RTT) is an X-linked neurological disorder caused by MECP2 mutations. Like other X-linked disorders, RTT patients have sex-specific differences in clinical presentation due to distinct cellular environments, where females have ~50% of cell […]
• GSE300413 Newly-diagnosed IDHwt MGMT unmethylated glioblastoma patients treated with standard radiation, nivolumab, and BMS-986205 May 6, 2026
  Contributors : Derek A Wainwright ; Lijie Zhai ; Bobby Brooke ; Steve Horvath ; Juozas Gordevicius ; Milda MilčiūtėSeries Type : Methylation profiling by genome tiling arrayOrganism : Homo sapiensImproving immunotherapeutic efficacy for patients with glioblastoma (GBM) has been suggested to be limited by a number of factors including indoleamine 2,3 dioxygen […]
• GSE317763 Immune Modulation of Macular Degeneration Through Natural Killer Cell Activity May 6, 2026
  Contributors : Sarah L Doyle ; Ema Ozaki ; Kiva Brennan ; Fiona M Roche ; Karsten HokampSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusAge-related macular degeneration (AMD) is the leading cause of irreversible blindness in the world and can result in pathological neovascularization in late-stage disease. Discovery of […]
• GSE329430 Bone marrow myelopoiesis dysfunction in Alzheimer’s disease May 6, 2026
  Contributors : Miguel A Abellanas ; Leyre Basurco ; Maitreyee Purnapatre ; Chiara Burgaletto ; Michal SchwartzSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Mus musculusWe have utilized single-cell RNA sequencing to analyze how Alzheimer's disease mouse model is affecting the bone marrow hematopoiesis at the single-ce […]
• GSE329526 Clonal lineage tracing reveals distinct invasive subpopulations in triple-negative breast cancer May 6, 2026
  Contributors : Carolina De Santiago ; Andrea L Gardner ; Patrick Parker ; Joshua R Thomas ; Gregory Callahan ; Mrigayu Ghosh ; Aaron B Baker ; Amy BrockSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensMetastatic dissemination in triple negative breast cancer (TNBC) arises from extensive intratumoral heterogeneity, yet th […]
• GSE329743 Ether lipid remodeling during neuronal differentiation prevents ferroptosis May 6, 2026
  Contributors : Antonino Asaro ; Giovanni D'AngeloSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensFerroptosis is a form of cell death driven by iron-dependent lipid peroxidation, with specific lipid species playing key roles in modulating susceptibility. Among these, ether lipids have shown conflicting effects, bein […]
• GSE329822 Single cell RNA-seq analysis of pMN neural progenitors from zebrafish 3dpf, 5dpf and 7dpf May 6, 2026
  Contributors : Appel Bruce ; Kearns Christina ; Arena Kimberly ; Orourke RebeccaSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioThe goal of this study was to identify distinct cell populations that arise from ventral spinal cord pMN progenitors. To do so, we sorted fluorescently marked pMN cells obtained from Tg(olig2:EG […]