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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE296401 Interleukin-23 promotes a pro-inflammatory Th17 cell state by stabilizing RORγt and suppressing glucocorticoid receptor activity II June 12, 2026Contributors : Dandan Yang ; Linglin Huang ; Ana C Anderson ; Vijay K KuchrooSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusInterleukin-23 receptor (IL-23R) signaling is critical for the generation of pro-inflammatory CD4+ IL-17-producing T cells (Th17) that can drive autoimmune tissue inflammation, but the underlying […]
- GSE286991 Sustained PRC1.1 activity preserves gene repression independently of PRC2.2 and restrains leukemic cell differentiation June 12, 2026Contributors : Fatemeh Mojallali ; Alessandra De Meis ; Sinne Alkema ; Tjerk-Jan Atsma ; Shanna M Hogeling ; Rianne Kloosterman ; Eve Ioannou ; Albertus Wierenga ; Gerwin Huls ; Joost Martens ; Jan-Jacob Schuringa ; Vincent van den BoomSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensLoss-of-function mutations in BCOR, a […]
- GSE299445 Taxodione Inhibits Glioblastoma Proliferation and Potentiates the Cytotoxicity of Paclitaxel June 12, 2026Contributors : Kyle J Parella ; Megan M Solans ; Cynthia Vied ; Svetlana N Kononenko ; Hanna Colegrove ; Diego A Zorio ; James H FrederichSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensGlioblastoma rapidly acquires resistance to conventional genotoxic therapy. This behavior is closely associated with the enhancement of […]
- GSE296502 A cell-intrinsic glucocorticoid biosynthesis and sensing circuit maintains homeostatic Th17 cell state June 12, 2026Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE301757 Deletion of Trdn-as transcription in the adult heart. June 12, 2026Contributors : Stefan Günther ; Theresa Hofmann ; Thomas Boettger ; Carsten KünneSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusDeletion of Trdn-as transcription in the mouse heart reveals a function of trdn-as in the control of TRDN processing as well as secondary changes induced be the alteration of the cardiac calci […]
- GSE299699 Gene expression profiling of hindpaw tissues in a spontaneous arthritis mouse model to explore pathological ossification and the effects of non-pharmacological interventions June 12, 2026Contributors : Gonz‡lez-Ch‡vez Susana AideŽ ; Pacheco-Tena CŽsar Francisco ; Chaparro-Barrera EduardoSeries Type : Expression profiling by arrayOrganism : Mus musculusSpondyloarthritis is a chronic inflammatory disease with limited therapeutic options, particularly for pathological bone formation. The spontaneous arthritis (SpAD) mouse model reproduces key f […]
- GSE335177 Genomic hallmarks of depot medroxyprogesterone acetate-associated meningiomas June 12, 2026Series Type : Expression profiling by high throughput sequencing ; Methylation profiling by genome tiling arrayOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
- GSE245937 Proper nuclear compartment reorganization in G1 phase is essential for DNA replication control [Hi-C] June 12, 2026Contributors : Asami Oji ; Takako Ichinose ; Izumi Noda ; Ichiro HirataniSeries Type : OtherOrganism : Mus musculusUpon G1 entry after mitosis, mammalian chromosomal DNA is spatially segregated into A and B compartments, which correlate well with classic euchromatin and heterochromatin, respectively. The significance of this spatial segregation, however, has […]
- GSE335230 Oxidative stress triggers RNAPII arrest through PARylation and DNA damage [ChIP-seq] June 12, 2026Contributors : Quentin A Thomas ; Liyang Wu ; Emma Lesage ; Henriette K Iversen ; David Lopez-Martinez ; Haiyue Liu ; Nicolas Nieto-Moreno ; Lea H GregersenSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensUV or gamma irradiation, as well as certain chemicals, generate DNA damage that disrupts transcription […]
- GSE335198 RNA-seq and ONT full-length transcriptome profiling of HCT116 and WiDr cells treated with DMSO, GSK025, or GSK715 June 12, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThis study profiles transcript abundance and full-length transcript isoforms in colorectal cancer cell lines after PRMT inhibitor treatment.
- GSE335232 Oxidative stress triggers RNAPII arrest through PARylation and DNA damage [ELCAP-seq] June 12, 2026Contributors : Quentin A Thomas ; Liyang Wu ; Emma Lesage ; Henriette K Iversen ; David Lopez-Martinez ; Haiyue Liu ; Nicolas Nieto-Moreno ; Lea H GregersenSeries Type : OtherOrganism : Homo sapiensUV or gamma irradiation, as well as certain chemicals, generate DNA damage that disrupts transcription through a variety of well-characterised mechanisms. In cont […]
- GSE335234 Oxidative stress triggers RNAPII arrest through PARylation and DNA damage [TTchem-seq] June 12, 2026Contributors : Quentin A Thomas ; Liyang Wu ; Emma Lesage ; Henriette K Iversen ; David Lopez-Martinez ; Haiyue Liu ; Nicolas Nieto-Moreno ; Lea H GregersenSeries Type : OtherOrganism : Homo sapiensUV or gamma irradiation, as well as certain chemicals, generate DNA damage that disrupts transcription through a variety of well-characterised mechanisms. In cont […]
- GSE335275 Mapping the spatial architecture of glioblastoma from core to edge delineates niche-specific tumor cell states and intercellular interactions [xenium_cohort3] June 12, 2026Contributors : Saad M Khan ; Anthony Z Wang ; Rupen R Desai ; Colin R McCornack ; Rui Sun ; Sonika M Dahiya ; Jennifer A Foltz ; Ngima D Sherpa ; Lydia Leavitt ; Timothy West ; Alexander F Wang ; Aleksandar Krbanjevic ; Bryan D Choi ; Eric C Leuthardt ; Bhuvic Patel ; Albert H Kim ; Gavin P Dunn ; Allegra A PettiSeries Type : OtherOrganism : Homo sapiensTrea […]
- GSE282372 LDB1 regulates gene expression and chromatin structure in pluripotency and lineage differentiation [RNA-seq] June 12, 2026Contributors : Heungsun Kwon ; Juhyun Kim ; Lecong Zhou ; Ann DeanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusChromatin organization is a pivotal factor in stem cell pluripotency and differentiation. However, despite considerable study, the role of enhancer looping protein LDB1 in these processes has not been explor […]
- GSE335176 Genomic hallmarks of depot medroxyprogesterone acetate-associated meningiomas [methylation] June 12, 2026Contributors : Sakibul Huq ; Taylor A Gatesman ; Hussam Abou-Al-Shaar ; David R Raleigh ; Constantinos G Hadjipanayis ; James C Bayley ; Georgios A Zenonos ; Thomas M Pearce ; Daniel F Marker ; Sameer Agnihotri ; Paul A GardnerSeries Type : Methylation profiling by genome tiling arrayOrganism : Homo sapiensIntegrated genomic characterization of meningiomas f […]