Category: pubmed

Gene Expression Omnibus Announcements & Study Releases

Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.

• GSE269055 Function of primary human mast cells (huMCs) in cholangiocarcinoma tissue. June 4, 2026
  Contributor : Zongli ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe tumor microenvironment of cholangiocarcinoma involves mast cells playing a crucial role. Given that cholangiocarcinoma is frequently associated with biliary obstruction and cholestasis, mast cells might exhibit distinctive pathological functio […]
• GSE296217 The promyelocytic leukemia PML protein is a key immune suppressor in triple-negative breast cancer June 4, 2026
  Contributors : Martina Uggè ; Cristina Fracassi ; Anna S Tascini ; Matteo Dugo ; Francesca GianneseSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTriple-negative breast cancer (TNBC) is an aggressive malignancy with limited treatment options and frequent resistance to immunotherapy. Here, we identify the targetable pro […]
• GSE272870 Butyrate is anti-inflammatory at low and pro-inflammatory at high concentrations June 4, 2026
  Contributors : Muwei Jiang ; Danny Incarnato ; Rutger Modderman ; Aina Altimira Lazaro ; Iris H Jonkers ; Frans Bianchi ; Geert van den BogaartSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensButyrate is a four-carbon short-chain fatty acid produced from microbial fermentation of dietary fibers present at high millimolar […]
• GSE296813 Targeting transcriptional addiction to pro-proliferative programs in pancreatic cancer [scRNA organoids] June 4, 2026
  Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe pancreas is a special organ which is considered both endocrine and exocrine. The exocrine pancreas gives rise to pancreatic ductal adenocarcinoma (PDAC), which accounts for the majority of pancreatic cancer cases. In recent years, various new therapeutic options for ca […]
• GSE296809 Targeting transcriptional addiction to pro-proliferative programs in pancreatic cancer [scATAC_Mice] June 4, 2026
  Series Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensThe pancreas is a special organ which is considered both endocrine and exocrine. The exocrine pancreas gives rise to pancreatic ductal adenocarcinoma (PDAC), which accounts for the majority of pancreatic cancer cases. In recent years, various new therapeutic […]
• GSE334209 Gene expression during overexpression of ArPHR2/4 in Anoectochilus roxburghii Leaves June 4, 2026
  Contributors : Shuguang Wang ; Aimin Lv ; Yi Zhang ; Hao LiSeries Type : Expression profiling by high throughput sequencingOrganism : Anoectochilus roxburghiiArPHR2/4 acts as the core transcription factors in response to phosphorus starvation. They regulate the responsive signaling pathways, especially the phosphorus signaling cascade, thereby modulating the […]
• GSE296818 Targeting transcriptional addiction to pro-proliferative programs in pancreatic cancer [scATAC organoids] June 4, 2026
  Series Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensThe pancreas is a special organ which is considered both endocrine and exocrine. The exocrine pancreas gives rise to pancreatic ductal adenocarcinoma (PDAC), which accounts for the majority of pancreatic cancer cases. In recent years, various new therapeutic […]
• GSE318405 NK2R signaling governs intestinal lipid mobilization and mucosal inflammation June 4, 2026
  Contributors : Pedro A Perez ; Chung-Chih Liu ; Alessandra Ferrari ; Nicole Littlejohn ; John P Kennelly ; Emma M Robinson ; Van T Nguyen-Tran ; Jon Athanacio ; Sean B Joseph ; Zaid Amso ; Peter Tontonoz ; Supriya SrinivasanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusNeuropeptidergic control of lipid metabolism is c […]
• GSE310137 Cellular Senescence in the Absence of Galactic Cosmic-Ray Muons June 4, 2026
  Contributors : Llop-Hernández Àngela ; López Júlia ; Verdura Sara ; Hernández-Antolin Rebecca ; Cid-Barrio Laura ; Peña-Garay Carlos ; Alarcón Tomás ; Cuyàs Elisabet ; Menendez Javier A.Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCellular senescence is a protective stress-response that halts cell proliferation to pr […]
• GSE325290 Mitochondria Directly Interact with the Nuclear Pore Complex June 4, 2026
  Contributors : Ivan Menendez-Montes ; Hesham A SadekSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMitochondria regulate cellular processes through direct and indirect interactions with other organelles. A well-studied example is contact with the endoplasmic reticulum at mitochondrial-associated ER membranes (MAMs)1, w […]
• GSE325048 Identification of novel CD52+ fibroblasts in nodular prostatic hyperplasia June 4, 2026
  Contributors : Oliver Strobel ; Hanyu Xia ; James Ropa ; Douglas Strand ; Travis Jerde ; Gustavo ArrizabalagaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBenign prostatic hyperplasia (BPH) and lower urinary tract symptoms are strongly associated with chronic prostate inflammation and stromal remodeling, yet the strom […]
• GSE333851 Spatial Glyco-Codes Define Human Liver Pathology and Progression June 4, 2026
  Contributor : Xiaolong TianSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Homo sapiensGlycosylation is a relatively underexplored aspect of the central dogma of biology, yet a key determinant of biological function and encodes disease-associated cellular states. However spatial glycomics is limited primarily by workflows t […]
• GSE333874 Small RNA sequencing reveals placental miRNAs linked to congenital transmission of Trypanosoma cruzi June 4, 2026
  Contributors : Andrea Diestra ; Alejandra Pando-Caciano ; Fredy Tinajeros ; Carla A Apaza-Quiroz ; Viviana Pinedo ; Vanessa Adaui ; Robert Gilman ; Natalie Bowman ; Mónica Pajuelo-TravesañoSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensBackground: Congenital transmission remains an important source of new Chagas di […]
• GSE333959 m6A reader IGF2BP3 promotes endometrial cancer progression through modification circ-EPB41L2 June 4, 2026
  Contributor : Shanrong ShuSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensEndometrial cancer ranks as the primary contributor to cancer related fatalities on a global scale. IGF2BP3 is a reader protein of m6A modification and plays an important role in the carcinogenesis of many solid tumors. Here, we explored the role […]
• GSE255090 Butyrate blocks specific histone acetylation June 4, 2026
  Contributors : Muwei Jiang ; Rutger Modderman ; Danny Incarnato ; Iris H Jonker ; Geert van den BogaartSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensButyrate, a short-chain fatty acid (SCFA) produced by microbial fermentation of dietary fiber, exerts beneficial metabolic and immunomodulatory functions th […]