Quick Links : Search PubMed , Finding Full Text , PubMed Advanced Search , Clinical Queries , Single Citation Matcher , FAQs & User Guide , Explore MeSH Database , Explore PubMed Journals
Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE291751 Profling of breast cancer cells using single-cell triomics analysis of DNA, RNA, and proteins with Tapestri chemistry December 15, 2025Contributors : Emma Jonasson ; Stefan Filges ; Anna Gustafsson ; Anders StåhlbergSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Homo sapiensCancer displays large heterogeneity both between and within tumors where intratumor heterogeneity can occur at genetical, transcriptional and translational level. The variability resul […]
- GSE237332 Transcriptional profiling of liver biopsies of precancerous viral hepatitis patients December 15, 2025Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
- GSE293629 The hegemonic EWSR1::ETS oncogene overrules core regulatory circuitry mechanisms in Ewing sarcoma [RNA-seq] December 15, 2025Contributors : Sandrine Grossetete ; Sakina Zaidi ; Karine Laud-Duval ; Didier Surdez ; Olivier DelattreSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensEwing sarcoma is an aggressive bone tumor of adolescence characterized by a hallmark EWSR1::FLI1 fusion oncogene. This chimeric protein drives tumorigenesis by reshaping […]
- GSE256000 Open chromatin, HIF binding and mRNA expression analysis in primary tubule and ccRCC cells [RNA-seq] December 15, 2025Contributors : Johannes Schödel ; Stephanie Naas ; René KrügerSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensInactivation of the von Hippel-Lindau tumor suppressor leads to stabilization of HIF transcription factors and subsequent oncogenic HIF-2 signaling in ccRCC. However, little is known about the transcriptional me […]
- GSE255765 MCF-7 ESR1 drug response bulk RNA December 15, 2025Contributors : Diana Wu ; Jenille Tan ; Russell Xie ; Marc HafnerSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo investigate the effect of single and combination treatments in breast cancer, we performed transcriptome profiling using bulk RNAseq
- GSE286170 A critical role of GABAergic neurons in driving CGG repeat toxicity associated with Fragile X Premutation Carriers [scRNA-Seq] December 15, 2025Contributors : Yulin Jin ; Yiqu Cao ; Wenjing Ma ; Peng JinSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusFragile X-associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder caused by a CGG repeat expansion (55-200) in the 5′ UTR of the fragile X messenger ribonucleoprotein 1 (FMR1) gene. The molecular […]
- GSE278355 Somatosensory nerves induce the pathologic response to physis injury December 15, 2025Contributors : Zhao Li ; Xin Xing ; Aaron JamesSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSomatosensory neurons are crucial for detecting a diverse repertoire of stimuli, including in skeletal tissues in which sensations of pain, pressure, and position are transmitted. Trauma to the physis often lead to pathologic […]
- GSE313501 Gel-free library preparation for next-generation RNA sequencing and small RNA quantification December 15, 2025Contributors : Ruixi Chen ; Daniel Yim ; Lili Liu ; Bo Cao ; Peter C DedonSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Escherichia coliNext-generation RNA sequencing (RNA-seq) is hampered by “primer dimer” (PD) artifacts and its quantitative performance reduced by polymerase fall-off (PF) at RNA modifications and secondary s […]
- GSE313494 Heterogeneity of senescent cells underlies resistance to ABT263 and ARV825 December 15, 2025Contributors : Masahiro Wakita ; Koyu Ito ; Hideka Miyagawa ; Kaho Fuji ; Dai Sakamoto ; Takumi Mikawa ; Sho Sugawara ; Xiangyu Zhou ; Jeong H Park ; Emi Ogasawara ; Akiko Takahashi ; Hiroshi Kondoh ; Naotada Ishihara ; Eiji HaraSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensABT263 and ARV825 emerged as promising senol […]
- GSE313662 Neoadjuvant modified FOLFIRINOX plus nivolumab in borderline-resectable pancreatic ductal adenocarcinoma: a pilot phase 1 trial December 15, 2025Contributors : Jason M Link ; Zev Wainberg ; Timothy DonahueSeries Type : OtherOrganism : Homo sapiensCombination therapies of chemotherapy and immune checkpoint inhibitors have failed to improve survival in pancreatic ductal adenocarcinoma (PDAC), except in rare MSI-H cases, despite their success in other solid tumors. Most prior studies have been conducted […]
- GSE313636 Spatial transcriptomic analysis of Naive or Yersinia pseudotuberculosis infected ileum reveals novel enterocyte transcriptional state December 15, 2025Contributors : Andrew P Hart ; Suhas Bobba ; Bethan Wallbank ; Igor Brodsky ; Daniel P BeitingSeries Type : OtherOrganism : Mus musculusAs part of the mouse ileum infection single cell and spatial transcriptomic atlas, GutPath (GutPath.org), these data provide 10X Xenium spatially resolved transcriptional information about the intestine during infection. Yer […]
- GSE313699 Loss of NADPH-producing enzymes accelerates pancreatic precancerous lesions December 15, 2025Contributors : Costas A Lyssiotis ; Megan D Radyk ; Justin A ColacinoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusAcinar-to-ductal metaplasia (ADM) is a reversible cell state that facilitates pancreas repair following injury. Oncogenic KRAS mutations can progress ADM to pancreatic intraepithelial neoplasia (PanIN) an […]
- GSE313717 Gene expression signature of liver of mice with and without functional NNT December 15, 2025Contributors : S Keipert ; D Lutter ; M Jastroch ; M Kutschke ; S Liedtke ; K MakrisSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusGlobal RNA sequencing analysis of liver of chow and high-fat diet fed WT and NNT KO mice (both sexes)
- GSE313774 A Microphysiological Model of Human MASLD Reveals Paradoxical Response to Resmetirom December 15, 2025Contributors : Dominick Hellen ; Jessica Ungerleider ; Erin Tevonian ; Pierre Sphabmixay ; Priyatanu Roy ; Nikolaos Meimetis ; Federico Presutti ; Ashleigh Williams ; Ryan Ogi ; Caroline Lewis ; Jacob Jeppesen ; Sixian You ; Damien Demozay ; Linda GriffithSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensMetabolic dysfunc […]
- GSE290622 Opposing functions of distinct regulatory T cell subsets in colorectal cancer December 15, 2025Contributors : Xiao Huang ; Dan Feng ; Sneha Mitra ; Emma S Andretta ; Nima B Hooshdaran ; Aazam P Ghelani ; Eric Y Wang ; Joe N Frost ; Victoria Lawless ; Aparna Vancheswaran ; Qingwen Jiang ; Christina S Leslie ; Alexander Y RudenskySeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensRegulatory T (Treg) cells are consider […]