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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE201089 Transcriptome analysis of eutopic endometrial mesenchymal stem cells in patients with adenomyosis by RNA-sequencing April 19, 2025Contributors : Tao Gui ; Guiping Wan ; Meiling CaoSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo identify differentially expressed genes (DEGs) and molecular pathways in endometrial mesenchymal stem cells (eMSCs) from adenomyosis patients and provide a new insight into disease mechanisms at transcriptome level.
- GSE253129 The m5C reader Ybx1 regulates embryonic cortical neurogenesis by promoting the progenitor cell cycle progression [E13.5-cKO_RNAseq] April 19, 2025Contributors : Jian Zhang ; Zhuoxuan Yang ; Pengfei Che ; Sheng-Jian JiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe reversible epitranscriptomic mark, 5-methylcytosine (m5C) modification, is implicated in numerous cellular processes, but its role in neuronal development remains largely unexplored. In this study, […]
- GSE253128 The m5C reader Ybx1 regulates embryonic cortical neurogenesis by promoting the progenitor cell cycle progression [E13.5-KD_RNAseq] April 19, 2025Contributors : Jian Zhang ; Zhuoxuan Yang ; Pengfei Che ; Sheng-Jian JiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe reversible epitranscriptomic mark, 5-methylcytosine (m5C) modification, is implicated in numerous cellular processes, but its role in neuronal development remains largely unexplored. In this study, […]
- GSE253131 The m5C reader Ybx1 regulates embryonic cortical neurogenesis by promoting the progenitor cell cycle progression [RIP-seq] April 19, 2025Contributors : Jian Zhang ; Zhuoxuan Yang ; Pengfei Che ; Sheng-Jian JiSeries Type : OtherOrganism : Mus musculusThe reversible epitranscriptomic mark, 5-methylcytosine (m5C) modification, is implicated in numerous cellular processes, but its role in neuronal development remains largely unexplored. In this study, we discovered high expression of the m5C read […]
- GSE253130 The m5C reader Ybx1 regulates embryonic cortical neurogenesis by promoting the progenitor cell cycle progression [E18.5-cKO_RNAseq] April 19, 2025Contributors : Jian Zhang ; Zhuoxuan Yang ; Pengfei Che ; Sheng-Jian JiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe reversible epitranscriptomic mark, 5-methylcytosine (m5C) modification, is implicated in numerous cellular processes, but its role in neuronal development remains largely unexplored. In this study, […]
- GSE253132 The m5C reader Ybx1 regulates embryonic cortical neurogenesis by promoting the progenitor cell cycle progression. April 19, 2025Series Type : Expression profiling by high throughput sequencing ; OtherOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE266404 SASP-related signals and SASP gene expression profiles in senescent cells after 18β-GA treatment. April 19, 2025Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe accumulation of senescent cells contributes to age-related organ degradation and susceptibility to chronic diseases. These cells exhibit the senescence-associated secretory phenotype (SASP), affecting cellular and overall aging. 18β-GA has anti-inflammatory effects。RNA […]
- GSE294494 Au18(L-NIBC)14 targets ASC oligomerization for autoimmune disease treatment April 19, 2025Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusGold nanoclusters (AuNCs), unlike conventional nanoparticles, possess molecular characteristics besides ultrasmall nano-features. Recently, we and others showed that AuNCs are promising in treatments of various major diseases. However, the AuNCs used were usually mixtures, […]
- GSE294508 Macrophage PKM2 depletion ameliorates hepatic inflammation and acute liver injury in mice April 19, 2025Contributors : Ziwei Kang ; Ruoyan Xie ; Yiming Cui ; Zhiwei Chen ; Jincheng Li ; Jinyu Lv ; Weijia YeSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPyruvate kinase M2 (PKM2), the rate-limiting enzyme of glycolysis, plays a critical role in macrophage activation and a broad spectrum of chronic liver diseases. However, […]
- GSE294844 Transcriptional signature for dysplastic epidermal development in human pre-malignant skin April 19, 2025Contributors : Sida Chen ; Olga Yarygina ; Emma Gutierrez ; David N Silvers ; David M OwensSeries Type : Expression profiling by high throughput sequencingOrganism : human skin metagenomeActinic keratosis (AK) is a prolific precancerous skin lesion, which occurs in susceptible individuals due to chronic ultraviolet radiation exposure, with a propensity to de […]