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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE326573 T-cell Multiomic Analysis Identifies Subsets and Mechanisms of Interaction with Epithelial Cells in Idiopathic Pulmonary Fibrosis July 14, 2026Contributors : Ana Serezani ; Julia Bazzano ; Bruno D Pascoalino ; Ludmilla Silva ; Abigail Dietrich ; Chase Taylor ; Taylor Sherrill ; Carla Calvi ; Paula Gonzalez-Ericsson ; Matthew Bacchetta ; Ciara Shaver ; Lorraine Ware ; Margaret Salisbury ; Luc Van Kaer ; Nicholas Banovich ; Jonathan Kropski ; Timothy BlackwellSeries Type : Expression profiling by hig […]
- GSE231690 Widespread transmission of DNA supercoiling and selective topoisomerase utilization regulates torsional stress within the neuronal genome [RNA-Seq] July 14, 2026Contributors : Amir Segev ; Ilse D Ramirez ; Lahiri Konada ; Morgan Crewe ; Ram MadabhushiSeries Type : Expression profiling by high throughput sequencing ; Third-party reanalysisOrganism : Mus musculusDNA supercoiling has the potential to alter gene transcription and chromatin topology, yet how its distribution is regulated on a genome-wide level is poorly […]
- GSE338478 Periconoid A, a Novel Ergosterol Derivative from Periconia caespitosa, Induces Apoptosis in Nasopharyngeal Carcinoma Cells Accompanied by the Enrichment of Inflammatory Pathways July 14, 2026Contributors : Jie Liu ; Jin-Long Huang ; Jing Wang ; Run-Qi Wang ; Tian-Tian Meng ; Jiao-Lin Bao ; Ren-Bo Ding ; Shuai DongSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensChemical investigation of marine Conus Literatus endophytic fungus Periconia caespitosa HDYXY-1 led to the isolation and characterization of seven no […]
- GSE279026 cGAS deficient mice display premature aging associated with loss of chromatin organization, derepression of LINE1 elements and induction of inflammation July 14, 2026Series Type : Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE271062 Comparative transcriptomics of Nipah virus infection in human and fruit bat cells July 14, 2026Contributors : Claudia Gonzalez ; Carine Rey ; Omran Allatif ; Severine Croze ; Olivier Reynard ; Branka HorvatSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiens ; Pteropus vampyrusWe used bulk RNA sequencing to investigate the transcriptomic signature of fruit bat and human cells after Nipah virus infection. We have infe […]
- GSE302966 Comparative phenotypic characterisation of mutant human bronchial epithelial cells in vitro and in vivo July 14, 2026Contributors : Carlos Lopez-Garcia ; Robert SellersSeries Type : OtherOrganism : Homo sapiensDevelopment of tractable and robust models of cancer depends on a transparent, detailed and critical evaluation of their advantages and disadvantages for their use in basic and translational cancer research. Specifically, identifying the phenotypic differences of can […]
- GSE295137 Targeting Regnase-1 unleashes CAR T cell antitumor activity for osteosarcoma and creates a proinflammatory tumor microenvironment [scRNAseq1] July 14, 2026Contributors : Adeleye Adeshakin ; Hao Shi ; Hongbo Chi ; Stephen GottschalkSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe took advantage of CAR T cells targeting B7-H3 in immune competent osteosarcoma models and evaluated the intrinsic and extrinsic effects of the known negative regulator Regnase-1 (Reg-1).
- GSE338196 Neuroimmune priming and microglial exhaustion in aged Gulf War Illness mice July 14, 2026Contributors : Kwang-Mook Jung ; Hye-Lim Lee ; Daniele PiomelliSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusGulf War Illness (GWI) affects up to one-third of 1990–1991 Gulf War veterans and is associated with chronic low-grade neuroinflammation, yet its cellular substrates remain unclear and targeted pharmacological […]
- GSE338180 Cell senescence emerges as a hallmark and therapeutic target of chronic intracellular infection July 14, 2026Contributors : Edoardo Scarpa ; Doriana Oliveri ; Diego Rondelli ; Carla Chernichero ; Federico Russo ; Riccardo Nodari ; Giorgia Moschetti ; Anna Griego ; Marta Zaccaria ; Federico Di Marco ; Fabio Saliu ; Gabriele Marchello ; Ferdinando Cannella ; Manuel Albanese ; Gianluca Cidonio ; Lara Manganaro ; Daniela M. Cirillo ; Raffaele De Francesco ; Sergio Abri […]
- GSE338199 Cannabidiol reverses neuroimmune priming in aged Gulf War Illness mice July 14, 2026Contributors : Kwang-Mook Jung ; Hye-Lim Lee ; Daniele PiomelliSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusGulf War Illness (GWI) affects up to one-third of 1990–1991 Gulf War veterans and is associated with chronic low-grade neuroinflammation, yet its cellular substrates remain unclear and targeted pharmacological […]
- GSE338197 Dissection of Poly(A)-binding protein (PABPC) cellular function using degron-mediated depletion with replacement July 14, 2026Contributors : Ryan Y Muller ; Kiara X Wang ; David P BartelSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCytoplasmic poly(A)-binding proteins (PABPCs) are essential and highly abundant regulators of mRNA stability and translation, but their cellular functions have been difficult to dissect due to slow turnover and th […]
- GSE338200 Cannabidiol reverses microglial exhaustion in aged Gulf War Illness mice July 14, 2026Contributors : Kwang-Mook Jung ; Hye-Lim Lee ; Daniele PiomelliSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusGulf War Illness (GWI) affects up to one-third of 1990–1991 Gulf War veterans and is associated with chronic low-grade neuroinflammation, yet its cellular substrates remain unclear and targeted pharmacological […]
- GSE338219 吡咯喹啉醌改善了自然衰老小鼠与增强线粒体生物能量相关的认知相关行为表现 July 14, 2026Contributors : 云 燕 ; 迪 鄧 ; 春霞 棕褐色Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe investigated whether pyrroloquinoline quinone (PQQ) could improve cognitive performance in twenty-month-old naturally aged mice and explored the potential mechanisms involved. Results showed that PQQ supplementation improved spatial work […]
- GSE338234 Effect of VEGF on miRNA profile in miR-1 overexpressing HUVECs for isomiR analysis study July 14, 2026Contributors : Asawari Korde ; Giovanni Nigita ; Shervin S TakyarSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensMiRNAs are generated through a finely tuned multi-step process that includes precise cropping and cleavage of their precursors. The mature miRNA is then loaded onto an argonaute (Ago) protein to form an R […]
- GSE320567 Targeting ZIP12-mediated Zn2+ signaling as a treatment for pulmonary hypertension July 14, 2026Contributors : Chien-Nien Chen ; Lan ZhaoSeries Type : Expression profiling by high throughput sequencingOrganism : Rattus norvegicusZIP12, a membrane bound zinc importer, is upregulated in the remodeled pulmonary arterioles of patients with pulmonary arterial hypertension (PAH). Genetic deletion of its encoding gene, slc39a12, ameliorates the disease in rod […]