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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE297837 ChAHP Silences SINE Retrotransposons by Inhibiting TFIIIB Recruitment. May 1, 2026Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE230539 IPA analysis of CD14-positive monocytes/macrophages from IBD patients and controls May 1, 2026Contributors : Simone Weber ; Sophia Sonnewald ; Stephen ReidSeries Type : Expression profiling by arrayOrganism : Homo sapiensthe gene expression profiles of CD14-positive cells from IBD and control patients were analyzed
- GSE299042 Transcriptome sequencing of hepatocytes (with or without GFP) during liver development in zebrafish May 1, 2026Contributors : Long Chen ; Sizhou HuangSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioThis study presents a comprehensive transcriptomic analysis of hepatocytes and non-hepatocytes during zebrafish liver development at 3 days post-fertilization (dpf), 7 dpf, and adult stages. Utilizing GFP-labeled hepatocytes from Tg(fa […]
- GSE279081 Gene Expression is Co-regulated by Non-nucleolar RNA Polymerase I [Cut & Tag] May 1, 2026Contributors : Carter Lucas ; Backman Vadim ; Almassalha LuaySeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensDue to its role in mRNA synthesis, many studies of the relationship between transcription and chromatin organization have focused on the regulation of RNA polymerase II (Pol-II) function by supranuc […]
- GSE266555 Parkinson's disease (PD) genetic asymmetry in SNCA PFF injected mouse model May 1, 2026Contributors : Gerhard A Coetzee ; Steven E Pierce ; Elizabeth EnsinkSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe measured gene expression in neuronal nuclei from cortex derived from both hemispheres (injected and noninjected side) of mice (16 male, 16 female) intected with either PBS or SNCA PFFs. Mice were sacri […]
- GSE296242 Sustained MYB activity drives emergent enhancer activation and precise enhancer-promoter interactions May 1, 2026Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencing ; OtherOrganism : Homo sapiens ; Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE295541 TCN2 promotes psoriatic skin inflammation and keratinocyte proliferation via the IL-1β-STAT3 pathway May 1, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPsoriasis, a chronic immune-mediated inflammatory skin disorder, exerts systemic impacts across multiple organs. Although transcobalamin 2 (TCN2) has been reported to be associated with several autoimmune diseases, its role in psoriasis remains elusive. Hence, we investiga […]
- GSE329151 Transcriptome of mouse brain perivascular macrophages (PVM) by RNA-seq May 1, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThis project includes transcriptome sequencing (RNA-seq) data of perivasccular macrophages (PVM) isolated from mouse brain. The goal is to compare the gene expression of PVM between young adult and aged mice to investigate aging-related changes.
- GSE329149 Transcriptomic Insights into the Adaptive Colonization of Escherichia coli O157:H7 during Production and Storage of Alfalfa Sprout May 1, 2026Contributors : Mostafa G Ali ; Ahmed E Yousef ; Ahmed G AbdelhamidSeries Type : Expression profiling by high throughput sequencingOrganism : Escherichia coli O157:H7 str. EDL933Shiga toxin-producing Escherichia coli (STEC) is a major foodborne pathogen associated with raw produce such as sprouts, where it encounters fluctuating nutrient, temperature, and oxi […]
- GSE329231 Epigenomic profiling of H3K9me3 and H3K27ac across melanoma cell lines with different mutational backgrounds May 1, 2026Contributors : Gongjie Wu ; Ferdinand KappesSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensMelanoma is a genetically and phenotypically heterogeneous cancer, and changes in chromatin state have been implicated in melanoma progression, phenotypic plasticity, and tumor behavior. To investigate the epigeneti […]
- GSE329198 PGC-1alpha pathway dysregulation disrupts myofiber specification in a mouse model of SBMA May 1, 2026Contributors : Curtis J Kuo ; Laura B Chopp ; Zhigang Yu ; Luhan Ni ; Hien T Zhao ; Janghoo Lim ; Andrew P LiebermanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSkeletal muscle pathology is a critical but poorly understood contributor to neuromuscular degeneration in spinal and bulbar muscular atrophy (SBMA), a CAG/p […]
- GSE329420 Endothelial exosomes remodel chromatin accessibility and superenhancer in cancer cells to promote liver metastatic colonization May 1, 2026Contributors : Jin Bei ; Liu Shenglan ; Huang Hongke ; Yang Luo ; Wei Dong ; Dai Wei ; Zhou Jingfeng ; Wang Yun ; Zhang Ping ; Ye Qianyun ; Pan JingxuanSeries Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensLiver-organotropic metastasis occurs in cancers such a […]
- GSE329498 Antigen-scaffolds loaded with hyper-stable Neoleukin-2/15 expand antigen-specific T cells with a favorable phenotype for adoptive cell therapy May 1, 2026Contributors : Maria Ormhøj ; Kamilla K Munk ; Siri Tvingsholm ; Keerthana Ramanathan ; Amalie K Bentzen ; Georgios Kladis ; Gitte N Aasbjerg ; Grigorii Nos ; Tripti Tamhane ; Hólmfridur R Halldórsdóttir ; Søren N Jakobsen ; Marcus S Frej ; Kristoffer H Johansen ; Mohammad Kadivar ; Sine R HadrupSeries Type : Expression profiling by high throughput sequencin […]
- GSE329577 Single-cell transcriptomic analysis of lipoprotein transport in yolk sac membrane endodermal epithelial cells of chicken embryos May 1, 2026Contributors : Jie-Ci Wu ; Zhao-Qi Hu ; Yuan-Yu Lin ; Harry John Mersmann ; Shih-Torng DingSeries Type : Expression profiling by high throughput sequencingOrganism : Gallus gallusThis study investigates the transcriptional landscape of yolk sac membrane (YSM) endodermal epithelial cells in chicken embryos using single-cell RNA sequencing. The yolk sac membra […]
- GSE297323 Bcl11b-Cxxc1 axis regulates stage-specific chromatin accessibility during thymocyte development [RNA-seq] May 1, 2026Contributors : Kazuki Okuyama ; Ichiro TaniuchiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusA zinc-finger (ZnF) transcription factor Bcl11b plays a pivotal role in T-lymphopoiesis. A mouse strain expressing a truncated form of Bcl11b lacking the C-terminal ZnF exhibited a dusrpted chromatin accessibility in CD4+CD8+ […]