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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE300082 Imidacloprid susceptibility is linked to life history regulation in honey bees (Apis mellifera) March 17, 2026Contributors : Gursimran Toor ; Robert Lu ; Olav RueppellSeries Type : Expression profiling by high throughput sequencingOrganism : Apis melliferaThe western honey bee (Apis mellifera) often encounters chemical stressors in the form of phytochemicals, or pesticide residues. The first line of defense against these agrochemicals is constitutively expressed det […]
- GSE295427 Targeting branched-chain amino acids alleviates pulmonary fibrosis [scRNA-seq] March 17, 2026Contributors : Jie Yao ; Miao Lei ; Na He ; Su Fang ; Wanli Peng ; Wenxiang HuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe previously confirmed that BCAT2 was reduced in TGF-β1-treated mouse and human lung fibroblasts. Knockdown of BCAT2 significantly promoted COL1A1 expression in response to TGF-β1 treatment. How […]
- GSE319077 Excitatory cortical neurons from CDKL5 deficiency disorder patient-derived organoids show early hyperexcitability not identified in neurogenin2 induced neurons [RNA-Seq] March 17, 2026Contributors : Madison R Glass ; Dosh Whye ; Nickesha C Anderson ; Delaney Wood ; Nina R Makhortova ; Taryn Polanco ; Kristina H Kim ; Kathleen E Donovan ; Gayathri Rajaram Srinivasan ; Lorenzo Vaccaro ; Ashish Jain ; Davide Cacchiarelli ; Liang Sun ; Elizabeth D Buttermore ; Mustafa SahinSeries Type : Expression profiling by high throughput sequencingOrgani […]
- GSE310764 The post-reproductive ovary shifts from a reproductive to an immune organ March 17, 2026Contributors : Aubrey Converse ; Ian P Schowe ; Shweta S Dipali ; Shivani S Jambunathan ; Emmett B Kelly ; Sarah R Ocanas ; Michael B Stout ; Michele T Pritchard ; Francesca E DuncanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusReproductive aging in females is characterized by the irreversible depletion of ovarian fol […]
- GSE289977 Subtype-specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers March 17, 2026Contributors : Nagarajan Sankari ; Mohan Sumitra ; Sheth H JigarSeries Type : OtherOrganism : Homo sapiensGene expression is tightly controlled by DNA elements called enhancers by associating with lineage-specific transcription factors. These enhancers transcribe noncoding RNAs (called enhancer RNAs or eRNAs). eRNA expression is an early indicator of transcr […]
- GSE319370 Hippo signaling differentially regulates distal progenitor subpopulations and their transitional states to construct the mammalian lungs March 17, 2026Contributors : Kuan Zhang ; Madhuri Basak ; Youssef Zaher ; Erica Yao ; Pao-Tien ChuangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusLung cells from Lats1f/f; Lats2f/f; SftpcCre/+ and littermate control mice were collected at embryonic day 14.5 (E14.5) and 17.5 (E17.5) for scRNA-seq.
- GSE324670 Genetic and heat-stress related environmental influences on pig whole-blood gene expression levels March 17, 2026Contributors : Laure Gress ; Katia Fève ; Arthur Durante ; Claire Naylies ; Yann Labrune ; Yannick Lippi ; Patrice Dehais ; Yvon Billon ; Mario Giorgi ; Denis Milan ; Jean-Luc Gourdine ; Hélène Gilbert ; David Renaudeau ; Juliette Riquet ; Guillaume DevaillySeries Type : Expression profiling by arrayOrganism : Sus scrofaThis study aims to use whole blood omi […]
- GSE292222 Macrophage-intrinsic and IL-9-dependent arginine metabolism promotes lung tumor growth March 17, 2026Contributors : Anthony M Cannon ; James Ropa ; Mark H KaplanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTumor-associated macrophages are an abundant, tumor-infiltrating cell population that supports the evasion of tumor cells from anti-tumoral immune cell detection by generating an immunosuppressive tumor-immune mic […]
- GSE324675 Parity-conditioned Hedgehog/VDR-linked NanoString profiling of histologically normal human breast tissue (BC360) March 17, 2026Contributors : Nicole Cruz-Reyes ; Joshua Ogony ; Pria J Westerman ; Melody Stallings-Mann ; Tanya Hoskin ; Bryan M McCauley ; Robert A Vierkant ; Laura Pacheco-Spann ; Jessica L Fischer ; Denice L Gehling ; Lisa R Seymour ; Mark E Sherman ; Amy C Degnim ; Stacey J Winham ; Derek C RadiskySeries Type : Expression profiling by arrayOrganism : Homo sapiensHist […]
- GSE324673 Feeder-Free Generation of Lymphatic Endothelial Cells from Human Induced Pluripotent Stem Cells March 17, 2026Contributors : Aditi Prasad ; Shrey Patel ; Simon Ng ; Clifford Liu ; Bruce D GelbSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe lymphatic system is vital for fluid balance, lipid transport, and immune function, but studying human lymphatic vasculature has been limited by poor access to primary LECs. Here, we prese […]
- GSE324676 Parity-conditioned Hedgehog/VDR-linked NanoString profiling of histologically normal human breast tissue (IO360) March 17, 2026Contributors : Nicole Cruz-Reyes ; Joshua Ogony ; Pria J Westerman ; Melody Stallings-Mann ; Tanya Hoskin ; Bryan M McCauley ; Robert A Vierkant ; Laura Pacheco-Spann ; Jessica L Fischer ; Denice L Gehling ; Lisa R Seymour ; Mark E Sherman ; Amy C Degnim ; Stacey J Winham ; Derek C RadiskySeries Type : Expression profiling by arrayOrganism : Homo sapiensHist […]
- GSE324677 Parity-conditioned Hedgehog/VDR-linked NanoString profiling of histologically normal human breast tissue March 17, 2026Series Type : Expression profiling by arrayOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
- GSE324683 Hierarchical microtopology and phase-specific delivery functionally restore ultra-long nerve continuity across species March 17, 2026Contributor : Shuxin DaiSeries Type : Expression profiling by high throughput sequencingOrganism : Rattus norvegicusRepairing ultra-long peripheral nerve defects remains a major clinical challenge, primarily due to the requirement for regenerative platforms to be capable of integrating spatial guidance with temporally resolved biochemical cues. To address th […]
- GSE295425 Targeting branched-chain amino acids alleviates pulmonary fibrosis [CUT&Tag, histone_modification] March 17, 2026Contributors : Jie Yao ; Miao Lei ; Na He ; Su Fang ; Wanli Peng ; Wenxiang HuSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusPurpose: Previous studies demonstrated that BCAA metabolic reprogramming induces idiopathic pulmonary fibrosis (IPF). This study investigates BCAA-mediated gene expression regulatio […]
- GSE324658 Gene expression analysis of human lymphoblastoid TK6 cells exposed to the carcinogen 3-methylcholanthrene (3-MCA) March 17, 2026Contributor : Yuko OgataSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensGene expression analysis of human lymphoblastoid TK6 cells exposed to the carcinogen 3-methylcholanthrene (3-MCA) was conducted. The information entropy of the transcriptome was measured to assess whether a change with biological significance occurr […]