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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE319685 10x 16plex flex scRNAseq with either uninfected or SARS-CoV-2 infected mouse lungs from WT or Ccr2-/- mice February 23, 2026Contributors : Lisabeth Pimenov ; Sylvia Knapp ; Riem Gawish ; Florian DeckertSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusRespiratory viral infections caused by SARS-CoV-2 and Influenza virus pose significant public health concerns, with severe outcomes for at-risk and even healthy patients. While disease severity i […]
- GSE319684 Timecourse of FACS sorted Ly6C+ monocytes, tissue resident alveolar macrophages (trAMs), monocyte derived alveolar macrophages (bmAMs) and epithelial cells from SARS-CoV-2 (maVie16) vs. IAV (PR8) infected mouse lungs February 23, 2026Contributors : Lisabeth Pimenov ; Sylvia Knapp ; Riem Gawish ; Florian DeckertSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusRespiratory viral infections caused by SARS-CoV-2 and Influenza virus pose significant public health concerns, with severe outcomes for at-risk and even healthy patients. While disease severity i […]
- GSE319833 HDAC1/2 -mediated repression of Wnt receptors controls polarity orientation in epidermal stem cells in C. elegans. February 23, 2026Contributors : Mar Ferrando-Marco ; Bea Garcia del Valle ; Mark Hintze ; Lucy Narunsky ; Amelia Lin ; Junyue Huang ; Shannon Edwards ; Michalis BarkoulasSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Caenorhabditis elegansIn this study we employ TargetedDamID to identify targets within the epidermis for the histone d […]
- GSE319801 Comprehensive molecular profiling of regenerated retinal neurons in the adult zebrafish February 23, 2026Contributors : Hoang Thanh ; Nagashima Mikiko ; Awad SherineSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioUnlike mammals, zebrafish possess a remarkable capacity to regenerate ablated retinal neurons. In response to cellular injury and death, Müller glia dedifferentiate into a stem cell state, and each gives rise to a […]
- GSE268328 Effects of blood criculating extracellular vesicles on social behaviors in mice: blood miRNA analysis February 23, 2026Contributors : Shin-ichi Kano ; David K Crossmann ; Eisuke Dohi ; Norimichi Ito ; Ken MatobaSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Mus musculusExtracellular vesicles (EVs) are cell-derived membrane vesicles that circulate throughout the body. Accordingly, circulating EVs and their associated molecules, such as RNAs and […]
- GSE320062 A Naïve RNA Sampling Core Enables Adaptive piRNA Specificity Against Transposable Elements [smallRNA] February 23, 2026Contributors : Dominik Handler ; W. Y. Wylan Wong ; Alexander Tsarev ; Rippei Hayashi ; Julius BrenneckeSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Drosophila melanogasterHow piRNA-mediated genome defense achieves specificity against transposons while sampling a complex transcriptome has remained unresolved. Here we show th […]
- GSE319950 Erk3 deletion drives oxidative adaptations in skeletal muscle February 23, 2026Contributors : Angel Loza Valdes ; Carlos Acosta-Gallo ; Toufic Kassouf ; Andrei Belykh ; Dominika Malińska ; Katia El Ghoz ; Rabih El-Merahbi ; Filip Dziaczkowski ; Katia El Ghoz ; Grzegorz Sumara ; Kasia Kolczyńska-MatysiakSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSkeletal muscle plays a central role in whole-bo […]
- GSE309256 Canonical transcription termination mechanisms explain a minority of operons in cyanobacteria February 23, 2026Contributors : Jennifer Cascino ; K. Julia Dierksheide ; Gene-Wei LiSeries Type : OtherOrganism : Synechococcus elongatus PCC 7942 = FACHB-805Cyanobacteria are the most abundant phototrophs and hold potential as a carbon-negative platform for bioengineering applications. However, these efforts have been hampered by limited mechanistic understanding of their […]
- GSE319957 Persistent Activation of Monocytes/Macrophages and Cell Senescence in SIV-Infected Macaques on ART February 23, 2026Contributors : Yilin Chen ; Xiaofeng Ding ; Sonalika Ray ; Siva Thirugnanam ; Robert Blair ; Ahmad Saied ; Sergiy Sukhanov ; Jay Kolls ; Woong-Ki Kim ; Patrice Delafontaine ; Jay Rappaport ; Xuebin Qin ; Namita RoutSeries Type : Expression profiling by high throughput sequencingOrganism : Macaca mulattaDespite effective viral suppression with antiretroviral […]
- GSE319955 Quiescent neural stem cells transiently become neuronal-like to coordinate long-range reactivation February 23, 2026Contributors : Jocelyn L.Y. Tang ; Andrea H. BrandSeries Type : Expression profiling by high throughput sequencingOrganism : Drosophila melanogasterReactivation of quiescent neural stem cells (qNSCs) is a coordinated process that generates new neurons and glia to maintain homeostasis or enable repair post-injury. Here, we discovered that NSC reactivation in […]
- GSE320009 Synergistic role of riboflavin-auxotrophic Enterococcus for MR1 expression and in-tra-tumoral mucosal associated invariant T (MAIT) cell activation February 23, 2026Contributors : Pakhi Birla ; Franck HousseauSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe role of mucosal invariant T (MAIT) cells in the lung tumor microenvironment re-mains poorly understood, especially in the setting of immune checkpoint inhibitors. We identified intratumoral MAIT cells from paired single cell […]
- GSE320060 A Naïve RNA Sampling Core Enables Adaptive piRNA Specificity Against Transposable Elements [RNA] February 23, 2026Contributors : Dominik Handler ; W. Y. Wylan Wong ; Alexander Tsarev ; Rippei Hayashi ; Julius BrenneckeSeries Type : Expression profiling by high throughput sequencingOrganism : Drosophila melanogasterHow piRNA-mediated genome defense achieves specificity against transposons while sampling a complex transcriptome has remained unresolved. Here we show that p […]
- GSE320061 A Naïve RNA Sampling Core Enables Adaptive piRNA Specificity Against Transposable Elements [CLIP] February 23, 2026Contributors : Dominik Handler ; W. Y. Wylan Wong ; Alexander Tsarev ; Rippei Hayashi ; Julius BrenneckeSeries Type : OtherOrganism : Drosophila melanogasterHow piRNA-mediated genome defense achieves specificity against transposons while sampling a complex transcriptome has remained unresolved. Here we show that piRNA biogenesis operates through pervasive, n […]
- GSE319156 Decoy Antibodies Block Extracellular HSP70, Prevent Self Signaling and Inhibit Melanoma Cell Survival February 23, 2026Contributors : Noam Ben-Shalom ; Shivang Parikh ; Lilach Abramovitz ; Ron Yefet ; Paulee Manich ; Dafna Tussia-Cohen ; Ori Moskowitz ; Roma Parikh ; Stav Melamed ; Ksenia Polonsky ; Sebastien Apcher ; Tzachi Hagai ; Merav Cohen ; Yochai Wolf ; Ronnie Shapira-Frommer ; Carmit Levy ; Natalia T FreundSeries Type : Expression profiling by high throughput sequenc […]
- GSE319900 Listerine® attenuates cytokine-induced inflammation and activates zinc–metallothionein responses in gingival fibroblasts February 23, 2026Contributors : Anna Podesser ; Xiaoyu Huang ; Panahipour Layla ; Reinhard GruberSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensGingival fibroblasts amplify periodontal inflammation by producing chemokines in response to pro-inflammatory cytokines. Mouth rinses directly contact the gingival tissues, yet their effects on […]