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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE288330 Molecular responses of amaranth species to abiotic stresses January 29, 2026Contributors : Ana P Barba ; José Cetz ; Esaú Bojorquez ; Jose P Martinez ; Antonio D Leon ; Eduardo Espitia ; Alfredo HerreraSeries Type : Expression profiling by high throughput sequencingOrganism : Amaranthus hybridus ; Amaranthus hypochondriacusAbiotic stress triggered by Drought or soil salinity impacts negatively on crop production. To better understan […]
- GSE289944 A plant histone H3.3-specific amino acid safeguards the deposition of H3K36 methylation for proper plant development and stress responses [G34] January 29, 2026Contributors : Danhua Jiang ; Xiaoyi LiSeries Type : Expression profiling by high throughput sequencingOrganism : Arabidopsis thalianaHistone variants are critical determinants for chromatin function with diverse regulatory mechanisms. The H3 variants, H3.1 and H3.3, evolved independently in animals and plants. A significant difference between H3.1 and H3.3 […]
- GSE288933 Pervasive and programmed nucleosome distortion patterns on single mammalian chromatin fibers January 29, 2026Contributors : Marty Yang ; Vijay Ramani ; Hannah RichterSeries Type : Genome binding/occupancy profiling by high throughput sequencing ; OtherOrganism : Homo sapiens ; Mus musculusWe present a genome-scale method to map the single-molecule co-occupancy of structurally distinct nucleosomes, subnucleosomes, and other protein-DNA interactions via long-read hig […]
- GSE317932 The antiseizure medication Stiripentol inhibits mitocondrial complex I by blocking early-stage electron transfer January 29, 2026Contributors : Cyrielle L Bouchez ; Thibaut Molinié ; Guillaume Duranthon ; Sebastian Lillo ; Corinne Pellon ; Nadia El Mammeri ; Benjamin Dartigues ; Philippe Pasdois ; Benoit Pinson ; Macha Nikolski ; Anne Devin ; Arnaud Mourier ; Roland T Ullrich ; Thomas DaubonSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe oxid […]
- GSE290084 A plant histone H3.3-specific amino acid safeguards the deposition of H3K36 methylation for proper plant development and stress responses [H3K36me3_ChIPseq] January 29, 2026Contributors : Danhua Jiang ; Xiaoyi LiSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Arabidopsis thalianaHistone variants are critical determinants for chromatin function with diverse regulatory mechanisms. The H3 variants, H3.1 and H3.3, evolved independently in animals and plants. A significant difference between […]
- GSE279149 CUL5 E3 ubiquitin ligase regulates the evasion of bladder cancer cells to CD8+ T cell-mediated killing by inhibiting autophagy January 29, 2026Contributors : Xincheng Gao ; Hui Zhang ; Guosong JiangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCD8+ T cells are capable of specifically targeting and eliminating malignant tumor cells, but tumor cells can develop resistance mechanisms to escape CD8+ T cell-mediated killing. Here, we performed a whole genome CRIS […]
- GSE193323 Hnf1a mutation in endocrine pancreas affect cell function and identity January 29, 2026Contributors : Thomas A Legøy ; Andreas F Mathisen ; Luiza Ghila ; Simona CheraSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPurpose: Hnf1a is an important regulator of pancreas development. Mutation in this gene in humans lead to Maturity Onset Diabetes of the Young 3. Previous studies have shown that Hnf1a is import […]
- GSE312455 Surprising regulatory plasticity for the conserved HOG pathway in diverse Saccharomyces cerevisiae strains January 29, 2026Contributors : Carson L Stacy ; Amanda N Scholes ; Tara N Stuecker ; Lily Pitts ; Jeffrey A LewisSeries Type : Expression profiling by high throughput sequencingOrganism : Saccharomyces cerevisiaeTimely signaling pathways activation allows cells to survive diverse environmental stress conditions. Mitogen-activated protein kinases (MAPKs) are a highly conserv […]
- GSE312053 Bridge to transplant using a flow-adaptive extracorporeal total artificial lung system following bilateral pneumonectomy for septic ARDS January 29, 2026Contributors : Yuanqing Yan ; Anitha Chandrasekhar ; Hee Chul Yang ; Teja Devarakonda ; Aaron Reynolds ; Anjana V. Yeldandi ; Arunachalam Ambalavan ; Chitaru Kurihara ; G.R. Scott Budinger ; Ankit BharatSeries Type : Other ; Expression profiling by high throughput sequencingOrganism : Homo sapiensAcute respiratory distress syndrome (ARDS), when complicated b […]
- GSE316798 Effects of rocking during sleep on the bulk transcriptome of mouse cerebral cortex. January 29, 2026Contributors : Reyila Simayi ; Letizia Santoni ; Sabrina Galizia ; Riccardo Avvisati ; Ester Biecher ; Luisa de Vivo ; Michele BellesiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTranscriptomic studies have revealed that sleep and wake states are associated with widespread changes in gene expression in the brain acro […]
- GSE315151 A Spatiotemporal Cell Atlas of the Developing Rat Tooth Germ Reveals Iron-Deficiency Induced Ameloblast Dysregulation January 29, 2026Contributors : Xianwei Yang ; Rui HanSeries Type : OtherOrganism : Rattus norvegicusIron deficiency anemia (IDA) during pregnancy is a crucial risk factor for dental caries in offspring, yet the cellular and molecular mechanisms underlying its impact on tooth development remain unclear. To elucidate the pathogenic mechanism in situ spatially, this study esta […]
- GSE317319 Wnt Activation and Dual SMAD Inhibition For Induction and Maintenance of Hindbrain-like Neural Stem Cell from hiPSCs [RNA-Seq] January 29, 2026Contributors : Ziadoon Al-Akashi ; Denise Zujur ; Nicholas Boyd-Gibbins ; Nathalie E Wiguna ; Masato Nakagawa ; Tetsuhiro Kikuchi ; Asuka Morizane ; Jun Takahashi ; Makoto IkeyaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensNeurons exhibit region-specific identities corresponding to functional distinctions across diffe […]
- GSE317604 Effects of ACTH and Dexamethasone on the Transcriptomic Profile of the Rat Adrenal Gland: An In Vivo Study January 29, 2026Contributors : Emilia Cicha ; Małgorzata Blatkiewicz ; Karol Jopek ; Marta Szyszka ; Piotr W Malendowicz ; Anna Olechnowicz ; Ludwik K Malendowicz ; Marcin RucinskiSeries Type : Expression profiling by arrayOrganism : Rattus norvegicusThe hypothalamic-pituitary-adrenal (HPA) axis plays a pivotal role in regulating stress responses through ACTH-stimulated glu […]
- GSE317696 Transcriptome profiling of human gonadal tissue in Differences of Sex Development January 29, 2026Contributor : Helena Fabbri-ScalletSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThis study investigates the transcriptomic landscape of human gonadal tissues from individuals with Differences of Sex Development (DSD). Bulk RNA sequencing was performed on dysgenetic testes, testes, ovaries, and ovotestes obtained from […]
- GSE282754 Ustilago maydis disrupts carbohydrate signaling networks to induce hypertrophy in host cells January 29, 2026Contributors : Yoon Joo Lee ; Dong Zhang ; Sara C Stolze ; Georgios Saridis ; Malaika K Ebert ; Hirofumi Nakagami ; Gunther DoehlemannSeries Type : Expression profiling by high throughput sequencingOrganism : Zea maysUstilago maydis infection in maize causes hypertrophic leaf tumors; however, the underlying mechanisms driving this excessive cell growth are u […]