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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE22685 Title update January 11, 2026Series Type : Expression profiling by arrayOrganism : Homo sapienssummary
- GSE173701 Next Generation Sequencing to evaluate effects of MiR26b on atherosclerotic mouse vessels January 11, 2026Contributors : Han Jin ; Emiel P Van der Vorst ; Linsey J PetersSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusIn this study, Apoe-/- control mice and Apoe-/-MiR26b-/- mice were placed on a HFD for 4 weeks. Aortic arch and thoracic aorta from these mice were used to perform NGS analysis.
- GSE143992 Role of mitofusins in oocyte development January 11, 2026Contributors : F H Sugiyama ; K F Carvalho ; C H Macabelli ; P Tizioto ; L L Coutinho ; R P Nociti ; M R ChiarattiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe performed RNA sequencing (RNAseq) analysis to determine the effect of single (Mfn1-/- or Mfn2-/-) and double (Mfn1-/- and Mfn2-/-; Mfn1&2-/-) knockouts […]
- GSE253330 Gut-Brain Axis Regulates Liver Anti-Tumor Immunity January 11, 2026Contributors : Bauer Kylynda ; Trehan Rajiv ; Ma Chi ; Greten TimSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusHepatic immunosuppression contributes to high mortality in liver cancer. Nerve activity has been implicated in peripheral immune response and tumor growth. Whether cholinergic neuroimmune interactions shape h […]
- GSE215220 RNA-Seq of VUMC-DIPG10 and HSJD-DIPG007 human diffuse intrinsic pontine glioma cells treated with a copper chelator January 11, 2026Contributors : Federica Saletta ; Daniele Mercatelli ; Federico Giorgi ; Orazio VittorioSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe report the application of RNA-sequencing of VUMC-DIPG10 and HSJD-DIPG007 human diffuse intrinsic pontine glioma cells treated with copper chelator Tetraethylenepentamine (TEPA) for 2 […]
- GSE301618 RBP4 inhibits tongue squamous cell carcinoma progression through inhibition of the PI3K/AKT signaling pathway and promotion of macrophage M1-type polarization January 11, 2026Contributors : Ying Yan ; Nan Miao ; Xiaofeng WangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTongue squamous cell carcinoma (TSCC) is a common type of oral mucosal epithelial malignancy that can severely affect patient quality of life. Therefore, novel therapeutic strategies for TSCC are needed. This study aimed to […]
- GSE315661 Uridine Diphosphate Drives Myeloid Differentiation and Functional Reprogramming Through Dynamic Transcriptional Networks January 11, 2026Contributors : Giuseppe Fiume ; Caterina Giordano ; Emilio Straface ; Debora GentileSeries Type : Expression profiling by arrayOrganism : Homo sapiensPBMC were stimulated with UDP (100 micromolar) or left untreated (NT) for the indicated points. RNA was extracted and subjected to Nanostring nCounter Immunology PanelThe expression of around 500 genes of immun […]
- GSE315767 Transcriptome Sequencing Analysis of Human Colorectal Cancer Cell Lines After ECM1 Knockdown January 11, 2026Contributor : Huihui XiaoSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo investigate the regulatory role of ECM1 in CCL20 expression in colorectal cancer, this study employed the human colorectal cancer SW620 cell line. Stable knockdown of ECM1 gene expression was achieved via shRNA, and single-cell transcriptome seq […]
- GSE315768 Gene expression of Sargassum micracanthum extracts on human deraml fibroblast cells January 11, 2026Contributors : Hyeongwoo Choi ; Tae-Hee Kim ; Dong-Joo Park ; Se-Chang Kim ; Bonggi Lee ; Hyen-Woo Kim ; Won-Kyo JungSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensSargassum micracanthum, a brown macroalga rich in bioactive metabolites, has been widely recognized for its pharmacological potential. However, its role in […]
- GSE315772 Myosin 5b Deficiency Alters Liver Proliferation, Zonation and Bile Acid Composition January 11, 2026Contributors : Piper R McKee ; Rachel Edens-Valentine ; Rachel Stubler ; Renata R do Nascimento ; Charulekha Packirisamy ; Casper van Altena ; Lauren Giordano ; Colleen LeBlanc ; Selene Shore ; Jessica H Hartman ; Robin Muise-Helmericks ; Andrew Percy ; Thomas D Horvath ; Kristen A Engevik ; Melinda A Engevik ; Amy C EngevikSeries Type : Expression profiling […]