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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE272615 Serial and regional assessment of the right ventricular molecular and functional response to pressure-loading December 31, 2025Contributors : Kana Yazaki ; Michael Dewar ; John Duaz ; Yohei Akazawa ; Mei Sun ; Golam Kabir ; Jean-Francois Dejardin ; Kim Connelly ; Mark Friedberg ; Scott HeximerSeries Type : Expression profiling by high throughput sequencingOrganism : Rattus norvegicusBackground: Right ventricular(RV) function determines outcomes in RV pressure-loading. A better under […]
- GSE215058 Single-cell RNA-sequencing of Gmnc and Mcidas knockout primary mouse tracheal epithelial cells (mTECs) December 31, 2025Contributors : Lauren Byrnes ; Rachel Deleon ; Jeremy Reiter ; Semil ChoksiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTissue function depends on the relative proportions of multiple cell types. In the airway, basal stem cells differentiate into both multiciliated and secretory cells, which together protect the lung […]
- GSE169613 Polybrominated diphenyl ethers (PBDEs) exposure during pregnancy alters microRNA expression profile in rat placenta December 31, 2025Contributors : Yijun Liu ; Yan XieSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Rattus norvegicusPolybrominated diphenyl ethers (PBDEs) are well-known endocrine disrupting chemicals (EDCs), and have been found to affect reproduction and development. The placenta, as the interface between maternal and fetal circulation, is con […]
- GSE237488 Polycomb and trithorax epigenetic marks regulate temperature response in the phytoplanktonic microalgae Ostreococcus tauri. December 31, 2025Series Type : Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism : Ostreococcus tauriThis SuperSeries is composed of the SubSeries listed below.
- GSE228735 HDAC7 is essential in early pre-germinal center formation and its deregulation is associated with DLBCL [GC] December 31, 2025Contributors : Ainara Meler ; Mar Gusi-Vives ; Oriol de Barrios ; Alba Azagra ; Olga Collazo ; Javier Melchor ; Alberto del Monte ; Balázs Győrffy ; Miriam Verdu-Bou ; José-Tomás Navarro ; José-Ignacio Martín-Subero ; Gaël Roué ; Almudena R Ramiro ; Sergio Roa ; Maribel ParraSeries Type : Expression profiling by high throughput sequencingOrganism : Mus muscu […]
- GSE261026 mRNA expression quantitative Analysis of mesenchymal stem cells (MSCs) treated with CaP@Sr-MOF compared with control I December 31, 2025Contributors : L Wei ; Z ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe goals of this study are to evaluate the mRNA expressions of genes in mesenchymal stem cells treated with CaP@Sr-MOF
- GSE249169 Gene expression profile at single cell level of endothelial cells (ECs) from LPS-injected PPARD-ECWT or PPARD-ECKO mouse lung December 31, 2025Contributors : Xiao Y Tian ; Huiling HongSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusVascular hyperpermeability is one of the hallmarks of sepsis and endotoxemia, which contributes to tissue inflammation and organ dysfunction. The peroxisome proliferator-activated receptor delta (PPARδ) is an anti-inflammatory trans […]
- GSE314755 Dasatinib resensitizes BRAF/MEK inhibitor efficacy in patient-derived xenografts from patients with progression on BRAF/MEK inhibitor treatment December 31, 2025Contributors : Vito W Rebecca ; Min Xiao ; Yeqing Chen ; Meenhard HerlynSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensAlthough BRAF/MEK inhibitor (BRAFi/MEKi) therapy initially shows high efficacy in patients with BRAFV600E/K cutaneous melanoma, resistance develops in over 75% of cases. We tested robustness of the umb […]
- GSE314689 Inhibiting Aberrant Interfacial Friction Regulates Cell Fate and Promotes Cartilage Regeneration December 31, 2025Contributor : Hongyu ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensAberrant interfacial friction, both within tissues and between tissues and implanted biomaterials, is an overlooked factor that can lead to suboptimal outcomes of tissue regeneration. The role of aberrant interfacial friction in modulating cell be […]
- GSE315036 Transcriptional profiling of ageing muscle satellite cells treated with recombinant human MG53 December 31, 2025Contributors : Jethro W Zih-Shuo ; Yanping Xu ; Hua ZhuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPurpose: Skeletal muscle satellite cells (SCs) are essential for muscle regeneration. MG53 (TRIM72) is a key regulator of membrane repair, but its role in SC fate decisions remains elusive. This study aims to investiga […]
- GSE314954 Oncolytic virotherapy and platinum-based chemotherapy synergize to potentiate anti-tumor immunity through targeted engagement of chemo-persistent bystander CD8+ T cells December 31, 2025Contributors : Yang yang ; Shuai Yue ; Junjian He ; Lilin Ye ; Xiangyu ChenSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe efficacy of combined chemotherapy and PD-1 immune checkpoint blockade (ICB) is constrained by a fundamental pharmacological conflict, as chemotherapy indiscriminately eliminates the proliferatin […]
- GSE315061 Effects of oxytocin receptor agonists on the hair growth ability of dermal papilla cells December 31, 2025Contributors : Tatsuto Kageyama ; Junji FukudaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe examined effects of oxytocin receptor agonists on the hair growth ability of dermal papilla cells.
- GSE315078 Regulation of ABC Transporters and Ergosterol Biosynthesis by the Transcription Factor FvADS-1 Controls Azole Resistance and Virulence in Fusarium verticillioides December 31, 2025Contributor : Yajing YinSeries Type : Expression profiling by high throughput sequencingOrganism : Fusarium verticillioidesFusarium verticillioides is a significant agricultural pathogen and an emerging causative agent of invasive fusariosis in clinical settings. Fusarium species frequently exhibit resistance to available antifungal agents, yet the molecular […]
- GSE315136 Comprehensive long-read transcriptome analysis uncovers alternative RNA processing feature and isoform diversity in ovarian cancer progression December 31, 2025Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensPost-transcriptional processing has a crucial but still largely unresolved dynamic change and role during the malignant progression of ovarian cancer, especially due to the limited read length of widely used short-read RNA sequencing being not enough to capture the transcr […]
- GSE269647 Beta2 adrenergic receptor-mediated abnormal myelopoiesis drives neuroinflammation in aged patients post traumatic brain injury December 31, 2025Contributors : Zhichao Lu ; Rui Jiang ; Chenxing Wang ; Jun XiaoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusShort title: Aged bone marrow drives neuroinflammation post TBI