Quick Links : Search PubMed , Finding Full Text , PubMed Advanced Search , Clinical Queries , Single Citation Matcher , FAQs & User Guide , Explore MeSH Database , Explore PubMed Journals
Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE280677 Transcriptomic profile of IL-10-producing B cells (B10) in response to IL-2 signal in vitro October 30, 2025Contributors : Maxime Maugendre ; Juliette Gauthier ; Simon Léonard ; Celine DelaloySeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusIL-2 is one of the first cytokine discovered but its complex roles in T cell effector functions has shadowed its function in B cell responses. B cells transiently expressed IL-2 receptor up […]
- GSE279908 Distinct roles of histone H2B ubiquitination at promoters and coding regions of Pol II-transcribed stress genes [RNA-Seq] October 30, 2025Contributors : Rubén Barrios ; Montserrat Vega ; Rebeca Gracia ; Susanna Boronat ; Sarela García-Santamarina ; Jason C Tanny ; José Ayté ; Elena HidalgoSeries Type : Expression profiling by high throughput sequencingOrganism : Schizosaccharomyces pombeInvestigate the role of DUBs in the transcriptional response to oxidative stress
- GSE244444 A human-specific microRNA controls the timing of excitatory synaptogenesis October 30, 2025Series Type : Expression profiling by high throughput sequencing ; Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
- GSE237171 To investigate role of bile acids in modulating regulatory T cell phenotype under cholestatic conditions October 30, 2025Contributors : Ramesh Kudira ; Alexander Miethke ; Zhang XiangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensRegulatory T cells (Tregs) were shown to protect from cholestatic liver injury. Here we investigate whether amphiregulin (AREG), a ligand for epithelial growth factor receptor (EGFR) which promotes epithelial re […]
- GSE276674 Vascular regeneration with adenovirally reprogrammed endothelial cells and their long-term neovascularization effects October 30, 2025Contributors : Sang-Ho Lee ; Yoshiaki Tanaka ; Seongho Bae ; Young-sup YoonSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensReprogrammed endothelial cells (rECs) have been generated directly from human fibroblasts for cell therapy by overexpression of a transcription factor, ETV2, through lentiviral vector. However, due […]
- GSE263421 Bruceine A protects nuclear receptor 4A1 from ubiquitin-degradation to alleviate mesangial proliferative glomerulonephritis October 30, 2025Contributors : Huating Hu ; Hudan Pan ; Runze Li ; Kancheng He ; Ruimin Tian ; Chuanghai Zhang ; Rongrong LiSeries Type : Expression profiling by high throughput sequencingOrganism : Rattus norvegicusThe nuclear receptor 4A1(NR4A1) plays a crucial role in maintaining cellular homeostasis and is involved in various disease processes; however, its functional r […]
- GSE306818 Stability and Progressive Differentiation of Tfr cells are intrinsically and extrinsically controlled by Tfh programs October 30, 2025Contributors : Peter T Sage ; Jeong-Mi Lee ; Paulo RaederSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Homo sapiens ; Mus musculusFollicular regulatory T (Tfr) cells restrain follicular helper T (Tfh) cell-mediated B cell responses in the germinal center (GC) reaction to optimize humoral immunity while limiting autoimmuni […]
- GSE278840 Transcription-Replication Conflict Resolution by Nuclear RNA Interference [Ago1 ChIP-seq] October 30, 2025Contributors : Teri Cheng ; Robert A MartienssenSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Schizosaccharomyces pombeRNA interference (RNAi) plays an important role in the nucleus critical to genome maintenance and heterochromatin silencing. In the fission yeast Schizosaccharomyces pombe, Dicer (Dcr1) also plays a […]
- GSE308109 Comparative transcriptomics as a key to understanding the adaptation mechanisms of Baikal sculpins to the deep-water habitat October 30, 2025Contributors : Yulia P Sapozhnikova ; Tuyana V Sidorova ; Anastasiya G Koroleva ; Evgenia A Vakhteeva ; Alexander A Epifantsev ; Vera M Yakhnenko ; Sergey A Potapov ; Tatyana V Butina ; Sergey V Kirilchik ; Lyubov V Sukhanova ; Ivan A Nebesnykh ; Igor V KhanaevSeries Type : Expression profiling by high throughput sequencingOrganism : Batrachocottus multiradi […]
- GSE307004 Stability and Progressive Differentiation of Tfr cells are intrinsically and extrinsically controlled by Tfh programs [TCR-seq] October 30, 2025Contributors : Peter T Sage ; Jeong-Mi Lee ; Paulo L RaederSeries Type : OtherOrganism : Mus musculusFollicular regulatory T (Tfr) cells restrain follicular helper T (Tfh) cell-mediated B cell responses in the germinal center (GC) reaction to optimize humoral immunity while limiting autoimmunity. The immune system partially regulates GC responses by controll […]
- GSE308392 Transcription-Replication Conflict Resolution by Nuclear RNA Interference [dRNH ChIP-seq] October 30, 2025Contributors : Teri Cheng ; Robert A MartienssenSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Schizosaccharomyces pombeRNA interference (RNAi) plays an important role in the nucleus critical to genome maintenance and heterochromatin silencing. In the fission yeast Schizosaccharomyces pombe, Dicer (Dcr1) also plays a […]
- GSE308593 Loss of Twist impairs tentacle development and induces epithelial neoplasia in the sea anemone Nematostella vectensis October 30, 2025Contributors : Patricio Ferrer Muguia ; Ulrich TechnauSeries Type : Expression profiling by high throughput sequencingOrganism : Nematostella vectensisThe basic helix-loop helix transcription factor Twist plays diverse roles in mesodermal development across bilaterians, but its function in cnidarians remains unclear. Here, we investigate the role of Twist in […]
- GSE309311 Transcriptomic Profiling of Bronchial Epithelium Reveals Dysregulated Interferon and Inflammatory Responses to Rhinovirus in Exacerbation-Prone Pediatric Asthma [scRNA-Seq] October 30, 2025Contributors : Naresh Doni Jayavelu ; Jason S. Debley ; Matthew C AltmanSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensHost factors influencing susceptibility to rhinovirus-induced asthma exacerbations remain poorly characterized. Using organotypic bronchial epithelial cultures from well-characterized children with ast […]
- GSE278850 Transcription-Replication Conflict Resolution by Nuclear RNA Interference October 30, 2025Series Type : Other ; Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencing ; Non-coding RNA profiling by high throughput sequencingOrganism : Schizosaccharomyces pombeThis SuperSeries is composed of the SubSeries listed below.
- GSE305511 DNA Methylation Profiles Predicting Response to Anti-PD-1-based Treatment in Patients with Advanced Gastric Cancer [Targeted Bisulfite-Seq] October 30, 2025Contributors : Wei Tang ; Zhixiong WangSeries Type : Methylation profiling by high throughput sequencingOrganism : Homo sapiensImmunotherapy has shown promise in treating gastric cancer, but predicting patient response remains challenging. In this study, DNA methylation levels at 20 specific CpG probes were measured in 69 tumor samples using targeted bisulfi […]