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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE245130 Impaired CD103+ T cell accumulation facilitates oxidative damage induced lung adenocarcinoma October 11, 2025Contributors : Yu Xu ; Haorui Luo ; Jiahao Wang ; Haifeng Liu ; Junwei Ma ; Hetian Yuan ; Jiao Wu ; Luonan Chen ; Zimu Deng ; Xiaolong LiuSeries Type : Expression profiling by high throughput sequencingOrganism : Immune microenvironment plays essential roles in tumor progression. The molecular mechanism underlying the regulation of immune surveillance in tum […]
- GSE244462 Molecular remodeling of myocardium in mice with melanocortin-4 receptor deletion before cardiac function impairment October 11, 2025Series Type : Expression profiling by high throughput sequencingOrganism : The melanocortin-4 receptor (MC4R) is highly expressed in the hypothalamus and mutations in this gene are closely associated with the development of hereditary obesity and early onset severe obesity in humans. It has been demonstrated that Mc4r is involved in the development of dilate […]
- GSE267198 Blocking Nuclear Receptor Nr4a3 Unlocks the Senescence Barrier to Promote Direct Cardiac Reprogramming October 11, 2025Contributors : Li Wang ; Mengxin Liu ; Zhangyi YuSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Direct cardiac reprogramming of fibroblast to cardiomyocytes represents a potential means of restoring cardiac function following injury. However, aged and adult fibroblast are less efficient for reprogramming compared wit […]
- GSE267156 Blocking Nuclear Receptor Nr4a3 Unlocks the Senescence Barrier to Promote Direct Cardiac Reprogramming October 11, 2025Contributors : Li Wang ; Mengxin Liu ; Zhangyi YuSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Direct cardiac reprogramming of fibroblast to cardiomyocytes represents a potential means of restoring cardiac function following injury. However, aged and adult fibroblast are less efficient for reprogramming compared wit […]
- GSE267381 Blocking Nuclear Receptor Nr4a3 Unlocks the Senescence Barrier to Promote Direct Cardiac Reprogramming [aged scRNA-seq] October 11, 2025Contributors : Li Wang ; Mengxin Liu ; Zhangyi YuSeries Type : Expression profiling by high throughput sequencingOrganism : Direct cardiac reprogramming of fibroblast to cardiomyocytes represents a potential means of restoring cardiac function following injury. However, aged and adult fibroblast are less efficient for reprogramming compared with neonatal fib […]
- GSE267380 Blocking Nuclear Receptor Nr4a3 Unlocks the Senescence Barrier to Promote Direct Cardiac Reprogramming [neonatal scRNA-seq] October 11, 2025Contributors : Li Wang ; Mengxin Liu ; Zhangyi YuSeries Type : Expression profiling by high throughput sequencingOrganism : Direct cardiac reprogramming of fibroblast to cardiomyocytes represents a potential means of restoring cardiac function following injury. However, aged and adult fibroblast are less efficient for reprogramming compared with neonatal fib […]
- GSE267464 Blocking Nuclear Receptor Nr4a3 Unlocks the Senescence Barrier to Promote Direct Cardiac Reprogramming October 11, 2025Contributors : Li Wang ; Mengxin Liu ; Zhangyi YuSeries Type : Expression profiling by high throughput sequencingOrganism : Direct cardiac reprogramming of fibroblast to cardiomyocytes represents a potential means of restoring cardiac function following injury. However, aged and adult fibroblast are less efficient for reprogramming compared with neonatal fib […]
- GSE304649 Myeloid Cell Adhesion Molecule 1 (CADM1) promotes pro-inflammatory signaling in human Inflammatory Bowel Diseases October 11, 2025Contributors : Kimberly Darlington ; Alexandria Shumway ; Chandon Sona ; Matthew Poy ; Shehzad SheikhSeries Type : Expression profiling by high throughput sequencingOrganism : Cytotoxic T cells have been postulated to facilitate the destruction of intestinal epithelium in inflammatory bowel diseases (IBDs). CADM1, which encodes a membrane adhesion protein th […]
- GSE267468 Blocking Nuclear Receptor Nr4a3 Unlocks the Senescence Barrier to Promote Direct Cardiac Reprogramming October 11, 2025Contributors : Li Wang ; Mengxin Liu ; Zhangyi YuSeries Type : Expression profiling by high throughput sequencingOrganism : Direct cardiac reprogramming of fibroblast to cardiomyocytes represents a potential means of restoring cardiac function following injury. However, aged and adult fibroblast are less efficient for reprogramming compared with neonatal fib […]
- GSE267466 Blocking Nuclear Receptor Nr4a3 Unlocks the Senescence Barrier to Promote Direct Cardiac Reprogramming October 11, 2025Contributors : Li Wang ; Mengxin Liu ; Zhangyi YuSeries Type : Expression profiling by high throughput sequencingOrganism : Direct cardiac reprogramming of fibroblast to cardiomyocytes represents a potential means of restoring cardiac function following injury. However, aged and adult fibroblast are less efficient for reprogramming compared with neonatal fib […]
- GSE267472 Blocking Nuclear Receptor Nr4a3 Unlocks the Senescence Barrier to Promote Direct Cardiac Reprogramming October 11, 2025Series Type : Expression profiling by high throughput sequencingOrganism : This SuperSeries is composed of the SubSeries listed below.
- GSE276832 Interactions between type of culture medium and addition of serum on development and gene expression of bovine blastocysts produced in vitro October 11, 2025Contributors : Camila Cuellar ; Esraa Ismail ; McKenzie Haimon ; Quinn Hoorn ; Fahong Yu ; Maria Rabaglino ; Peter HansenSeries Type : Expression profiling by high throughput sequencingOrganism : Serum is commonly added to culture medium used for producing bovine embryos in vitro. Here it was tested whether addition of bovine serum to embryo culture medium i […]
- GSE293986 MeRIP-seq and RNA-seq Reveals RNA m6A Methylation Patterns and Gene Expression Profile of Arabidopsis Plants in Response to CMV Infection [MeRIP-Seq] October 11, 2025Contributors : Jiahui Liu ; Yujing Lin ; Chengguo DuanSeries Type : Methylation profiling by high throughput sequencingOrganism : We reported that m6A plays a positive role in plant defense against virus pathogen Cucumber mosaic virus (CMV). CMV genomic RNAs can be m6A modified during plant infection, leading to reduced stability of viral RNAs. Dysfunctions […]
- GSE216222 Screening and identification of transcriptomic expression profiles of mice with bone cancer pain October 11, 2025Contributors : Guangda Zheng ; Yiting Tang ; Yupeng Chen ; Yaoyuan Li ; Mingzhu Yang ; Qiuhu Zheng ; Yanju BaoSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : To map the transcriptomic expression profiles of mice with bone cancer pain (BCP).
- GSE267416 Blocking Nuclear Receptor Nr4a3 Unlocks the Senescence Barrier to Promote Direct Cardiac Reprogramming October 11, 2025Contributors : Li Wang ; Mengxin Liu ; Zhangyi YuSeries Type : Expression profiling by high throughput sequencingOrganism : Direct cardiac reprogramming of fibroblast to cardiomyocytes represents a potential means of restoring cardiac function following injury. However, aged and adult fibroblast are less efficient for reprogramming compared with neonatal fib […]