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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE266571 Nuclear functions of CFAP20 in transcription and replication [ChIP-seq] May 20, 2025Contributors : Daphne C Boer ; Sidrit Uruci ; Paul W Chrystal ; Ibrahim Ilik ; Andreas Panagopoulos ; George Yakoub ; Annelotte P Wondergem ; Klaas de Lint ; Tiemen J Wendel ; Sem J Brussee ; Nila K van Overbeek ; Román González-Prieto ; Jolanthe Lingeman ; Mats Ljungman ; Haico van Attikum ; Alfred O Vertegaal ; Sylvie M Noordermeer ; Rob F Wolthuis ; Vince […]
- GSE250579 Satb1 directs the differentiation of TH17 cells through suppression of IL-2 expression May 20, 2025Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : This SuperSeries is composed of the SubSeries listed below.
- GSE267945 Aging-Related Increase in Hepatic Microbiota and Glutamine Promotes M2 Polarization of Macrophage in the Aging Liver May 20, 2025Series Type : Expression profiling by high throughput sequencingOrganism : In the aging liver, a distinct senescence-associated secretory phenotype (SASP) and a concomitant influx of inflammatory cells are observed. Traditionally considered an immune-privileged site, the etiology of pronounced immune cell infiltration into the liver during senescence remains […]
- GSE266575 Nuclear functions of CFAP20 in transcription and replication May 20, 2025Series Type : Expression profiling by high throughput sequencing ; Other ; Genome binding/occupancy profiling by high throughput sequencingOrganism : This SuperSeries is composed of the SubSeries listed below.
- GSE278733 scRNAseq analysis of WT and tfeb-tfe3s triple knock-out zebrafish adult liver and embryos at 5 days post fertilization May 20, 2025Contributors : Alberto Rissone ; Martina La Spina ; Erica Bresciani ; Syed Zulfeqhar ; Chris Combs ; Martha Kirby ; Abdel Elkahloun ; Vicky Chen ; Raman Sood ; Shawn Burgess ; Rosa PuertollanoSeries Type : Expression profiling by high throughput sequencingOrganism : The transcription factors tfeb and tfe3 belong to the MiT/TFE gene family and are known as ma […]
- GSE277295 RNA-seq Reveals Paxillin as a Key Facilitator of Endothelial Cell Migration and Angiogenesis after Spinal Cord Injury May 20, 2025Contributors : Manjeet Chopra ; Jaidev Sharma ; Aditya A Singh ; Zarna Pathak ; Priyanka P Vats ; Vibhor Kumar ; Amit Mandoli ; Hemant KumarSeries Type : Expression profiling by high throughput sequencingOrganism : Spinal cord injury (SCI) is a catastrophic condition resulting in significant neurological deficits. To map the altered pathways within the lesio […]
- GSE297344 Analysis of a BCOR internal tandem duplication in mouse embryonic stem cell to neuronal precursor differentiation May 20, 2025Contributors : Zuzer Dhoondia ; Mitzi I KurodaSeries Type : Expression profiling by high throughput sequencingOrganism : BCOR (BCL-6 corepressor) is a component of variant Polycomb Repressive Complex 1.1 (vPRC1.1), one of several vPRC1 complexes that catalyze histone H2A ubiquitination thought to play an important role in PRC2 binding and the deposition of H […]
- GSE297709 STING agonists drive recruitment and intrinsic type I interferon responses in monocytic lineage cells for optimal anti-tumor immunity May 20, 2025Contributors : Melanie Girard ; Tania WattsSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : To define how intrinsic IFN-I signalling downstream of intratumoral STING agonist treatment alters the transcriptional state of myeloid cells, CITE-sequencing was performed on immune cells derived from the LNs and tumors of Ifnar1 mix […]
- GSE297521 Single-cell RNA sequencing reveals the effects of mental stress on mouse mammary tumors and the tumor microenvironment May 20, 2025Contributors : Wenjing Ma ; Pengfei Liu ; Tao Wang ; Jinhui Lü ; Weizhong Wang ; Qifan Tang ; Yixing Wang ; Jing Di ; Evelyne Bischof ; Qian Zhao ; Zuoren YuSeries Type : Expression profiling by high throughput sequencingOrganism : Mental stress has been shown to negatively impact the development and progression of human cancer, including breast cancer. Howe […]
- GSE297431 Disrupted MOS signaling alters meiotic cell cycle regulation and the egg transcriptome May 20, 2025Contributors : Gisela Cairo ; Olha Kholod ; Olivia Palmer ; Brittany A Goods ; Soni LacefieldSeries Type : Expression profiling by high throughput sequencingOrganism : Loss of MOS in female mice disrupts metaphase II arrest, potentially causing infertility and germ cell tumors. Single-egg RNA sequencing revealed widespread gene expression changes in mos -/- […]
- GSE297551 Loss of age-associated increase in m6A-modified RNA contributes to GABAergic dysregulation in Alzheimer’s disease May 20, 2025Contributors : Jenna Libera ; Junming Hu ; Tuyet-Anh Nguyen ; Zihan Wang ; Sophie J. F. van der Spek ; Kamryn Schult ; Luke Dorrian ; Jordan Majka ; Katarnut Tobunluepop ; Sambhavi Puri ; Alexander Kynshov ; Nicholas M. Kanaan ; Peter T. Nelson ; Kate Meyer ; Lei Hou ; Xiaoling Zhang ; Benjamin WolozinSeries Type : Expression profiling by high throughput seq […]
- GSE297566 Hippocampal epitranscriptomic (m6A) in human model of Temporal Lobe Epilepsy May 20, 2025Contributors : Marc-Michel Wilson ; Gary P BrennanSeries Type : Methylation profiling by array ; OtherOrganism : Analogous to DNA methylation and protein phosphorylation it is now well understood that RNA is also subject to extensive processing and modification. N6-methyladenosine (m6A) is the most abundant internal RNA modification and regulates RNA fate in […]
- GSE297707 Beneficial Effects of High Intensity Interval Training in a Mouse Model of Hypertrophic Cardiomyopathy May 20, 2025Contributors : Jonathan Herrera ; Vasia Barka ; Michael Morley ; Yifan Yang ; Danielle Szczesniak ; Kate Szczesniak ; Rose-Carmel Goddard ; Christoper McAllister ; Jaime Yob ; Graham Branscom ; Sharlene M DaySeries Type : Expression profiling by high throughput sequencingOrganism : High intensity exercise (HIE) has become a prominent training modality used t […]
- GSE244634 Direct genetic transformation bypasses tumor-associated DNA methylation alterations (RRBS) May 20, 2025Contributors : Sara Hetzel ; Eran Hodis ; Elena Torlai Triglia ; Alexander Kovacsovics ; Kathleen Steinmann ; Andreas Gnirke ; Meiying Cui ; Daniel McQuaid ; Raha Weigert ; Georg Pohl ; Mandar D Muzumdar ; Serge Leyvraz ; Ulrich Keilholz ; Marie-Laure Yaspo ; Aviv Regev ; Zachary D Smith ; Helene Kretzmer ; Alexander MeissnerSeries Type : Methylation profili […]
- GSE297342 Assessing the Effects of Silver Nanoparticles on ARPE-19 Cells via High-Throughput Phenotypic Profiling with the Cell Painting Assay. May 20, 2025Contributors : Gabrielle Byrd ; Alice Goldstein-Plesser ; Jo Nyffeler ; Clinton M Willis ; Anna Fisher ; William K Boyes ; Joshua A HarrillSeries Type : Expression profiling by high throughput sequencingOrganism : Increasing commercialization of silver nanoparticles (AgNPs) has resulted in elevated opportunity for human exposure and outpaced traditional risk […]