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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE295184 The effect of UV irradiation on the distribution of RNAPII NTD and DIS3 August 2, 2026Contributors : Elin Enervald ; Indranil Sinha ; Neus VisaSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensIt is well established that exposure to UV light alters the distribution of RNA polymerase II (RNAPII), but the impact of UV irradiation on the genomic distribution of DIS3 has not been investigated. We […]
- GSE287355 An EZH2—SREBP2 axis promotes cholesterol biosynthesis and represents a noncanonical vulnerability in tumorigenesis August 2, 2026Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiens ; Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE303341 A unified network systems approach uncovers a core program underlying T follicular helper cell differentiation [ATAC-seq] August 2, 2026Contributors : Vinay S Mahajan ; Hamid Mattoo ; Viswanadham Vinayak ; Grace J YuenSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensWe investigated Tfh cell differentiation across multiple levels of biological organization by integrating diverse data types through interpretable network-based approaches. Our […]
- GSE301176 Effect of adenoviral COVID-19 vaccines on human umbilical vein endothelial cells August 2, 2026Contributors : Aino Sormonen ; Nihay Laham-Karam ; Einari Niskanen ; Seppo Ylä-HerttualaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCoronavirus disease 2019 (COVID-19) continues to cause outbreaks around the world despite the vast vaccination programs against it. Thus, it is important to keep developing better vacci […]
- GSE341768 Transcriptional profiling of 3 dpf and 5 dpf WT zebrafish intestinal epithelial cells August 2, 2026Contributors : Daniel Levic ; Michel Bagnat ; Carina BlockSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioFor this experiment, we analyzed gene expression changes and intron splicing events in the WT zebrafish intestine at two developmental stages (3 dpf and 5 dpf). To perform this analysis, we collected > 125 M paire […]
- GSE303342 A unified network systems approach uncovers a core program underlying T follicular helper cell differentiation [RNA-Seq] August 2, 2026Contributors : Vinay S Mahajan ; Hamid Mattoo ; Viswanadham Vinayak ; Grace J YuenSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe investigated Tfh cell differentiation across multiple levels of biological organization by integrating diverse data types through interpretable network-based approaches. Our multi-scale ne […]
- GSE306389 Polystyrene microplastics disrupt ovarian development via cytoskeletal remodeling and epigenetic reprogramming particularly in granulosa cells [ATAC-seq] August 2, 2026Contributor : Mengyao LiuSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusThe emerging environmental health issue posed by micro (nano) plastics (MNPs) has raised significant concerns. Accumulating evidence suggested that MNPs can bioaccumulate in gonads and impair fertility in animals, yet the underlying c […]
- GSE210344 The 3D architecture of the genome determines specificity of HNF1β-mediated gene regulation (ChIP-Seq) August 2, 2026Contributors : Lotte Tholen ; Eveline Kahlman ; Peter Krijger ; Branco Heuts ; Amin Allahyar ; Joost Martens ; Wouter de Laat ; Joost Hoenderop ; Jeroen de BaaijSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusCell-type specific gene expression patterns are essential for kidney function. This is governed by […]
- GSE309314 Lecithin-cholesterol acyltransferase Lcat promotes hepatic steatosis through fatty acid metabolism reprogramming in zebrafish larvae August 2, 2026Contributors : Yuanyuan Fu ; Junjie Xu ; Lei LiSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioLecithin-cholesterol acyltransferase (Lcat), the key enzyme in reverse cholesterol transport (RCT), has been traditionally recognized for its role in high-density lipoprotein (HDL) maturation and systemic cholesterol homeostasi […]
- GSE306390 Polystyrene microplastics disrupt ovarian development via cytoskeletal remodeling and epigenetic reprogramming particularly in granulosa cells [scRNA-seq] August 2, 2026Contributor : Mengyao LiuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe emerging environmental health issue posed by micro (nano) plastics (MNPs) has raised significant concerns. Accumulating evidence suggested that MNPs can bioaccumulate in gonads and impair fertility in animals, yet the underlying cellular mechan […]
- GSE318367 Transcriptomic analysis of colchicine effects in adenine-induced chronic kidney disease August 2, 2026Contributors : Gyuri Kim ; Ga Young Heo ; Seung Hyeok HanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusColchicine is an anti-inflammatory drug that has emerged as a therapeutic option in various inflammatory diseases, but its role in chronic kidney disease (CKD) remains unclear. This study investigates the reno-protec […]
- GSE327974 The absence of Trim28 in nephron progenitors results in impaired kidney development and function August 2, 2026Contributors : Balazs Palhazi ; Alireza Paikari ; Silke Appenzeller ; Fabian Imdahl ; Matthias Becker ; Manfred GesslerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe TRIM28 gene encodes a transcriptional regulator involved in a variety of molecular processes. Inactivation of TRIM28 has been linked to the epithelial […]
- GSE328254 Collagen-heparan sulfate microcarriers support mesenchymal stem cell culture in microgravity and streamline post-flight recovery August 2, 2026Contributors : Maribella Domenech-Garcia ; Camilo Mora ; Leonel Velez-RomanSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensThe objective of this study was to validate a scalable, integrated workflow for Mesenchymal Stem Cell (MSC) culture in Low Earth Orbit (LEO) using pre-seeded, surface-engineered microcarriers (u […]
- GSE210346 The 3D architecture of gene regulation in the distal convoluted tubule August 2, 2026Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE305839 Polystyrene microplastics disrupt ovarian development via cytoskeletal remodeling and epigenetic reprogramming particularly in granulosa cells August 2, 2026Contributor : Mengyao LiuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe emerging environmental health issue posed by micro (nano) plastics (MNPs) has raised significant concerns. Accumulating evidence suggested that MNPs can bioaccumulate in gonads and impair fertility in animals, yet the underlying cellular mechan […]