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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE299426 In situ fate mapping identifies the neonatal origin of platelet-biased hematopoietic stem cells [Tppp3Naive] March 30, 2026Contributors : Marta López-Osias ; Elvira González-Saiz ; Daniel Fernández-Pérez ; Pedro Sánchez ; Indranil Singh ; Anna Adrover ; Alejo E Rodríguez-FraticelliSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusHematopoietic stem cells (HSCs) display heritable and deterministic gene regulatory states associated with functio […]
- GSE299003 In situ fate mapping identifies the neonatal origin of platelet-biased hematopoietic stem cells [TransplantTracing_Tppp3] March 30, 2026Contributors : Marta López-Osias ; Elvira González-Saiz ; Daniel Fernández-Pérez ; Pedro Sánchez ; Indranil Singh ; Anna Adrover ; Alejo E Rodríguez-FraticelliSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusHematopoietic stem cells (HSCs) display heritable and deterministic gene regulatory states associated with functio […]
- GSE309791 Inhalable Nanomedicine Targeting Macrophages for Modulation of the STING Pathway in Pulmonary Fibrosis Therapy March 30, 2026Contributors : Yangeng Wang ; Yang LiuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusIdiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease characterized by excessive immune activation and irreversible scarring of lung tissue. Recent evidence suggests that aberrant activation of the st […]
- GSE305094 In vivo RNA metabolic labeling identifies the sentinel cells of the regenerating zebrafish heart [scrna-seq] March 30, 2026Contributors : Janita Mintcheva ; Tzu-Lun Tseng ; Pinelopi Goumenaki ; Anika Neuschulz ; Anis Senoussi ; Ronny Schäfer ; Sara Lelek ; Daniela Panakova ; Didier Stainier ; Jan Philipp JunkerSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioThe adult zebrafish heart has high regenerative capacity. Heart injury triggers a cas […]
- GSE228535 Xenoestrogen-induced elimination of asymmetric gene expression in the Müllerian ducts of female Japanese quail embryos March 30, 2026Contributors : Shinji Tsukahara ; Suzuki TakehiroSeries Type : Expression profiling by high throughput sequencingOrganism : Coturnix japonicaAn RNA-seq analysis was performed to determine the differentially expressed genes between the left and right Müllerian ducts of female Japanese quail embryos with or without in ovo xenoestrogen exposure.
- GSE325991 High-resolution spatial transcriptomics of human adrenal neoplasms March 30, 2026Contributors : Tomohiro Tamura ; Masaki Uchihara ; Kotaro Umamoto ; Akiyo TanabeSeries Type : OtherOrganism : Homo sapiensTo characterize the tumor microenvironment and elucidate mechanisms of immune evasion in malignant adrenal tumors, we performed spatial transcriptomics (Visium HD) on pathological specimens from adrenocortical adenoma (ACA) and pheochromo […]
- GSE325535 The Chromatin Remodeler, Mit1, Enables the Propagation of the Histone Modification, H3K9me March 30, 2026Contributors : Melissa Seman ; Alexandria Latuda ; Fenting Huang ; Agnisrota Mazumder ; Luca Wolfstadter ; Sigurd Braun ; Kaushik RagunathanSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Schizosaccharomyces pombeChromatin structure dynamically regulates the balance between DNA accessibility and compaction, which is e […]
- GSE272559 Antiviral Tfh response by “tolerant” congenitally infected virus carriers drives antibody-mediated viral load control March 30, 2026Series Type : Other ; Expression profiling by high throughput sequencingOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE325763 The retinoic acid receptor transcriptional coregulator RIP140 predicts poor outcome and restrains ATRA response in acute myeloid leukemia March 30, 2026Contributors : Valentin Jacquier ; Vincent Cavaillès ; Catherine TeyssierSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensDespite advances in acute myeloid leukemia (AML) therapy, overall survival remains poor except in acute promyelocytic leukemia (APL), where all-trans retinoic acid (ATRA) dramatically improved outcome […]
- GSE325723 Cell size-dependent mRNA transcription drives proteome remodeling [SLAM-seq] March 30, 2026Contributors : Dong Shin You ; Christopher H Bohrer ; Purva H Rumde ; Ioannis Sanidas ; Matthew P Swaffer ; Daniel R Larson ; Josh E Elias ; Michael C Lanz ; Jan M SkotheimSeries Type : OtherOrganism : Homo sapiensIncreasing cell size drives proteomic changes that impact cell physiology. However, the molecular basis of size-dependent proteome remodeling has […]
- GSE325852 Translatome profiling reveals opposing alterations in inhibitory and excitatory neurons of Fragile X mice and identifies EPAC2 as a therapeutic target March 30, 2026Contributors : Anand Suresh ; Nazim Kourdougli ; Toshihiro Nomura ; Jessie E Buth ; Soledad Miranda-Rottmann ; Carlos A Sanchez-Leon ; Michelle W Wu ; Sofia M Nelson ; Lauren T Wall ; Anne T Tran ; Roberto Araya ; Anis Contractor ; Michael J Gandal ; Carlos Portera-CailliauSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculu […]
- GSE325919 Mitochondrial remodeling in skeletal muscle underlies exercise-induced reversal of age-associated functional decline in mice and humans March 30, 2026Contributors : Esther García-Domínguez ; José A Enríquez ; María C Gómez-CabreraSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusRNA-seq experiment to investigate the effect of training on muscle tissue in WT C57BL/6J and G6PD-tg mice. The goal of the study is to assess differential gene expression related to genotype an […]
- GSE325983 Lactate-driven H3K18 lactylation promotes cisplatin resistance in bladder cancer via HNRNPF-Parkin mediated mitophagy March 30, 2026Contributors : Henghui Zhang ; Dongqing Li ; Mingqiang Su ; Zaosong Zheng ; Wei Chen ; Haiyong ChenSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensCisplatin resistance in bladder cancer (BCa) is driven by metabolic reprogramming that enhances glycolysis and lactate production. Here, we report that lactate- […]
- GSE298178 Investigating the role of muscle fibers in the early stage of nerve regeneration within a Muscle-in-Vein graft March 30, 2026Contributors : Federica Zen ; Giulio Ferrero ; Alessandro Crosio ; Debora Molinaro ; Giulia Ronchi ; Stefano Geuna ; Giovanna Gambarotta ; Stefania RaimondoSeries Type : Expression profiling by high throughput sequencingOrganism : Rattus norvegicusBackground: Every year, many people experience a reduced quality of life due to peripheral nerve damage, resulti […]
- GSE325489 Spatiomolecular mapping reveals anatomical organization of heterogeneous cell types in the human nucleus accumbens March 30, 2026Contributors : Prashanti Ravichandran ; Svitlana V Bach ; Robert A Phillips III ; Madeline R Valentine ; Nicholas J Eagles ; Yufeng Du ; Ishbel del Rosario ; Haya A AlGrain ; Sarah E Maguire ; Ryan A Miller ; Heena R Divecha ; Madhavi Tippani ; Kelsey D Montgomery ; Joel E Kleinman ; Shizhong Han ; Stephanie C Page ; Thomas M Hyde ; Keri Martinowich ; Stepha […]