Author: Editor

Gene Expression Omnibus Announcements & Study Releases

Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.

• GSE271578 Kinetical scRNAseq Analysis Reveals Immune Mechanisms Underlying Hindered Lung Recovery following Influenza Virus Infection in Aged Hosts December 28, 2025
  Contributors : Jie Sun ; Yue WuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusAging is a major risk factor for host morbidity and mortality upon acute respiratory virus infections. To better elucidate the immune determinants of viral pathogenesis during aging, we conducted a time-course single-cell RNA sequencing (scRN […]
• GSE269417 Single embryo total RNA sequencing to map the effect of maternal SETDB1 on the 2-celll and 8-cell transcriptome December 28, 2025
  Contributors : Piroska E Szabó ; Tie-Bo Zeng ; Zhen FuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusEmbryos with maternal mutation of the H3K9 methyltransferase SETDB1 die before implantation. We tested the role of maternal SETDB1 in the timely processes of the preimplantation stage embryo. Using single embryo total R […]
• GSE304452 3D genome organization in tissue regeneration: functional requirement of long-range chromatin loops [Hi-C] December 28, 2025
  Contributors : Palmira Llorens-Giralt ; Carlos Camilleri-Robles ; Leo Zuber ; Jenisha Khadka ; Maria Marti-Marimon ; Florenci Serras ; Maria C Gambetta ; Marc A Marti-Renom ; Montserrat CorominasSeries Type : OtherOrganism : Drosophila melanogasterThe three-dimensional (3D) organization of the genome plays a fundamental role in gene expression regulation. Ho […]
• GSE279749 Combination of PARP and KRAS G12D Inhibitors Enhances Efficacy of Therapeutic Vulnerabilities December 28, 2025
  Contributors : Xin Xu ; Xin Chen ; Rongli Xu ; Ming DengSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo elucidate the molecular basis of the HR deficiency induced by KRASG12D inhibition, we conducted RNA sequencing (RNA-seq) on KRASG12D -mutant PDAC cells (AsPC-1, PANC-1, SW1990) treated with MRTX1133 and KRASG12V -m […]
• GSE304453 3D genome organization in tissue regeneration: functional requirement of long-range chromatin loops [RNA-seq] December 28, 2025
  Contributors : Palmira Llorens-Giralt ; Carlos Camilleri-Robles ; Leo Zuber ; Jenisha Khadka ; Maria Marti-Marimon ; Florenci Serras ; Maria C Gambetta ; Marc A Marti-Renom ; Montserrat CorominasSeries Type : Expression profiling by high throughput sequencingOrganism : Drosophila melanogasterThe three-dimensional (3D) organization of the genome plays a funda […]
• GSE309596 Combination of PARP and KRASG12D Inhibitors Enhances Therapeutic Efficacy by Exploiting Vulnerabilities(scRNA) December 28, 2025
  Contributors : Xin Xu ; Xin Chen ; Rongli Xu ; Min DengSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusCombination of PARP and KRAS G12D Inhibitors Enhances Efficacy Therapeutic Vulnerabilities in PDAC
• GSE314908 Chip-seq data for FGFR3-driven gene regulatory network analysis reveals a pro-tumoral role for p63 in luminal bladder tumors. December 28, 2025
  Contributors : Isabelle Bernard-Pierrot ; Xiang-Yu Meng ; Lilia Estrada-Virrueta ; Guerric Gilbert ; Helene Neyret-KahnSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensFGFR3 (Fibroblast Growth Factor Receptor 3) is one of the most frequently altered genes in bladder cancer, primarily through activating muta […]
• GSE314937 Profound effect of asparagine-linked glycosylation protein 11 (TgALG11) on genomic expression of Toxoplasma gondii II December 28, 2025
  Contributors : Feng Tan ; Yani Mou ; Siyu TianSeries Type : Expression profiling by high throughput sequencingOrganism : Toxoplasma gondiiToxoplasma gondii is an intracellular parasite that relies on complex molecular mechanisms to support its proliferation and survival. In this study, we investigate the role of TgALG11 in these processes and explore the und […]
• GSE314977 Enteric adenovirus antibody reactivity in year-1 infant serum measured using a protein microarray December 28, 2025
  Contributor : Jennifer HendrickSeries Type : Protein profiling by protein arrayOrganism : Homo sapiens ; unidentified adenovirusProcessed and raw enteric adenovirus protein microarray reactivity data from 119 year-1 infant serum samples from a Bangladeshi birth cohort, with sample-level metadata aligned to Table 1 of the associated manuscript (Hendrick J, et […]