Author: Editor

Gene Expression Omnibus Announcements & Study Releases

Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.

• GSE250248 RNA-seq analysis of tumor-infiltrating effector T cells isolated from subcutaneous mouse Lewis lung carcinoma (LLC) tumors May 3, 2026
  Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe goal of this study was to analyze differences in gene expression between tumor-infiltrating effector T cells with higher or lower uptake of the 2-deoxyglucose analog 2-NBDG in vivo. Mice bearing subcutaneous LLC tumors were injected intravenously with the 2-deoxyglucos […]
• GSE274672 Transcriptomic profile of patient derived glioblastoma stem cells from recurrent and newly diagnosed background May 3, 2026
  Contributors : S Sarkar ; A Ashokan ; B Surnar ; D G Eichberg ; T I Slepak ; M E Ivan ; S DharSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensMetabolic rewiring of neoplastic cells can fuel tumorigenicity of cancer stem cells contributing to tumor recurrence. One such cancer is glioblastoma for which tumor recurrence is […]
• GSE267738 Gene expression profile of various brain cells obtained from APP-KI mice May 3, 2026
  Contributors : Ruedl Christiane ; Wu Xiaoting ; Miller James ASeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBrain cells, such as, oligodendrocytes, and neurons, interact with each other to maintain brain homeostasis. Here, we utilize scRNAseq to investigate the significant phenotypic heterogeneity of different brain c […]
• GSE318527 Effect of CST3 knockout on gene expression in THP-1-derived macrophages May 3, 2026
  Contributor : Jie ZhaoSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo systematically investigate the biological role of CST3 in macrophages, we performed RNA-seq on THP-1-derived macrophages from wildtype (CST3+/+) and CST3 knockout (CST3-/-) backgrounds. Comparative transcriptomic analysis revealed differential expr […]
• GSE297032 Atopic asthma lowers nasal mucosal sphingolipids May 3, 2026
  Contributors : Zenna Solomon ; Rika Gomi ; Zoe Verzani ; Andrea Heras ; Perdita Permaul ; Uthra Balaji ; Jinghua Gu ; Sarah Brown ; Natalia Huerta ; Natalie Gosnell ; Paul Christos ; Jennie G Ono ; Tilla S Worgall ; Stefan WorgallSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensGenetic variations at the 17q21 asthma-risk […]
• GSE319204 scRNA analysis of inflamed and uninflamed colon tissues of Crohn's disease patients May 3, 2026
  Contributor : Jie ZhaoSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensSingle-cell RNA sequencing was performed on colonic tissues from Crohn’s disease patients, comparing inflammatory and non-inflammatory regions. The dataset characterizes cell-type composition and inflammation-associated transcriptional changes at sing […]
• GSE329021 Bulk RNA-seq of head tissue from wild-type and twist mutant Nematostella vectensis May 3, 2026
  Contributors : Patricio Ferrer Muguia ; Ulrich TechnauSeries Type : Expression profiling by high throughput sequencingOrganism : Nematostella vectensisThe basic helix-loop-helix transcription factor Twist plays roles in mesodermal development and tissue morphogenesis. To assess transcriptional changes associated with loss of Twist function, we performed bulk […]
• GSE329317 Adaptive Hypothesis Testing of Body Color Polymorphism in Rana dybowskii: From Behavior to Transcription May 3, 2026
  Contributors : Yicheng Duan ; Zhiyu Guo ; Jiajun Zhang ; Yinzi YeSeries Type : Expression profiling by high throughput sequencingOrganism : Rana dybowskiiTo explore the adaptive mechanisms and molecular basis of body color polymorphism in Rana dybowskii, we conducted body color plasticity experiments, color plate preference behavioral experiments, COI gene-b […]
• GSE329398 CD109 is dynamically expressed in endothelial and endocardial subpopulations during heart development, modulates endothelial cell behavior in vitro, but is not required for cardiovascular morphogenesis May 3, 2026
  Contributors : Andrew B Harvey ; Jeremy L Barth ; Andy WesselsSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCD109 encodes a GPI-linked glycoprotein that acts as a signaling modulator in the TGF-β pathway. CD109 has emerged in several genome-wide association studies as linked to coronary artery disease, myocardial infa […]
• GSE329456 Exosomal lncRNA Microarray Profiling May 3, 2026
  Contributor : Ye ChenSeries Type : Non-coding RNA profiling by arrayOrganism : Homo sapiensExosomes were isolated from the culture supernatants of lymphocytes in two groups, and lncRNAs within the exosomes were identified using microarray sequencing.