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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE296772 Assessment of the Health Effects of Phytopharmaceuticals Used in Potato Cultivation [Brain] May 25, 2026Contributors : Anca Lucau-Danila ; Sandy Theysgeur ; Camille Dugardin ; Sebastien LemièreSeries Type : Expression profiling by arrayOrganism : Mus musculusPotatoes are one of the most widely consumed staple foods globally, yet their cultivation and storage often involve the use of multiple phytopharmaceutical products, raising concerns about potential health […]
- GSE298513 Endothelial cell-intrinsic NOD2 signaling regulates the intestinal immune response through the generation of effector and memory T cells. May 25, 2026Contributors : Boyan K Tsankov ; Dana J PhilpottSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusCrohn’s disease (CD) involves aberrant intestinal T cell immunity, and genetic variants associated with disease development. Notably, mutations impairing NOD2 signaling represent the largest genetic risk factor for CD. Parado […]
- GSE297912 Development of an AI Model to Predict Tumor Immune Responsiveness in Colorectal Cancer Using Organoid–Immune Co-Culture platforms May 25, 2026Contributors : Misun Park ; Jiyeon Kim ; Jinguen Rheey ; Jihwan Park ; Ji-yeon ParkSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThis study aimed to functionally assess tumor immune responsiveness in colorectal cancer using a co-culture platform combining patient-derived organoids (PDOs) with autologous tumor-reactive […]
- GSE304836 Sequencing of human dermal fibroblasts May 25, 2026Contributor : Lei ShiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensComplete the sequencing of primary and in vitro cultured human fibroblasts, explore the transcriptomic characteristics of human fibroblasts and their transcriptomic changes during in vitro culture. This will facilitate more in-depth research on the phy […]
- GSE301554 The impact of Fulvestrant on Estrogen Receptor-Driven Chromatin Dynamics in breast cancer cells points to a disconnect between chromatin opening and histone acetylation [ATAC-seq] May 25, 2026Contributors : Céline Barlier ; Mathias Simplicien ; Elsa Moreau ; Celia Fontana ; Aurelia Delherme ; Vincent Piras ; Gaylor Boulay ; Isabel PaivaSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensBackground: Epigenetic dysregulations are linked to various diseases, including cancer. Among them, breast cancer […]
- GSE83224 Transcriptional Regulatory Networks Involved in Melanogenesis Uncovered by Chemo-genomic Profiling May 25, 2026Contributors : Krishnamurthy Natarajan ; Kritika KirtySeries Type : Expression profiling by arrayOrganism : Mus musculusThis study was aimed to identify genome-wide changes in the transcriptome profile of mouse B16-F10 melanoma cells undergoing melanogenesis. The pigmentation state of the B16 cells could be controlled depending on the media conditions. We in […]
- GSE310741 Characterizing breast cancer cell biochemical responses to fluid shear in a 3D loading model May 25, 2026Contributors : Shreya Venkatesh ; Andrea Ordonez ; William R Thompson ; Edward B Chuong ; Maureen E LynchSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensBone is the most common site of breast cancer metastasis—only 12% of patients with skeletal metastases demonstrate a 5-year survival rate after diagnosis. Bone metastas […]
- GSE331524 Transcriptomic analysis of hippocampus and prefrontal cortex in a mouse model of chronic radiation-induced gastrointestinal injury May 25, 2026Contributors : Hyosun Jang ; Yeonghoon Son ; Hae-June LeeSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusChronic radiation-induced gastrointestinal injury is associated with persistent gut dysfunction and microbiome alterations, which may contribute to extra-intestinal complications including neurovascular and behaviora […]
- GSE331507 Multi-omics profiling of glioma cells treated with I-BRD9 May 25, 2026Contributors : Yuanlang Hu ; Kang Ouyang ; Jiayi Lyu ; Chunyu CaoSeries Type : Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism : Homo sapiensBRD9 is a glioma-associated epigenetic regulator. This study profiles transcriptomic and chromatin-level changes in glioma cells after I-BRD9 […]
- GSE331535 TOR-dependent transcriptome responses to water deficit in Arabidopsis seedlings May 25, 2026Contributors : Dhriti Singh ; Ashverya LaxmiSeries Type : Expression profiling by arrayOrganism : Arabidopsis ; Arabidopsis thalianaTo assess the role of TOR kinase, Col-0 and TOR RNAi (tori 35-7) seedlings were subjected to water-deficit treatment and analyzed using Affymetrix microarrays.Comparative transcriptome profiling of Col-0 and TOR RNAi seedlings w […]
- GSE331532 Identification and Characterization of MicroRNAs in female 0edaleus asiaticus(Orthoptera:Oedipodidae) May 25, 2026Contributors : Shuangshuang Ge ; Shujing GAOSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Oedaleus asiaticusOedaleus asiaticus is a dominant grasshopper in northern China’s grasslands and agro-pastoral zones, yet its growth and development miRNA regulation remains poorly understood. Here, we performed small RNA sequencing on […]
- GSE331537 Transcriptomic analysis of two rice varieties, QJ and LJ, with differential responses to bicarbonate-induced salt-alkali stress. May 25, 2026Contributors : Bo Qin ; Tie Li ; Minglong Sun ; Yuanling Zhao ; Dongmei LiSeries Type : Expression profiling by high throughput sequencingOrganism : Oryza sativaThis study aimed to elucidate the molecular mechanisms underlying the response to salt‑alkali stress by analyzing transcriptomic changes in two rice varieties, QJ and LJ, which exhibit differential r […]
- GSE332556 Tumor-associated Macrophage GnT-V Enhances Sensitivity to Antitumor Immunotherapy through Branched N-Glycosylation to Promote M1 Polarization May 25, 2026Contributor : Depeng YangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTumor tissues with differential sensitivity to immunotherapy were sequenced using The DNBelab C4 /DNBelab TaiM4 Series Single-Cell Library Prep Set (MGI) was used for sequencing and sequenced on the DNBSEQ-T7 sequencer with pair-end sequencing. Imm […]
- GSE332566 Study of the predictive value of genomic, transcriptomic and epigenetic biomarkers in patients with recurrent and/or metastatic head and neck squamous cell carcinoma treated with PD-1/PD-L1 inhibitors May 25, 2026Series Type : Methylation profiling by genome tiling arrayOrganism : Homo sapiensImmune checkpoint inhibitors have improved survival in several solid tumors, including head and neck squamous cell carcinoma (HNSCC). However, current use of PD-1/PD-L1 inhibitors relies on PD-L1 expression, which does not reliably predict patient response. Therefore, better pre […]
- GSE296688 Assessment of the Health Effects of Phytopharmaceuticals Used in Potato Cultivation [Jejunum] May 25, 2026Contributors : Anca Lucau-Danila ; Sandy Theysgeur ; Camille Dugardin ; Sebastien LemièreSeries Type : Expression profiling by arrayOrganism : Mus musculusPotatoes are one of the most widely consumed staple foods globally, yet their cultivation and storage often involve the use of multiple phytopharmaceutical products, raising concerns about potential health […]