Quick Links : Search PubMed , Finding Full Text , PubMed Advanced Search , Clinical Queries , Single Citation Matcher , FAQs & User Guide , Explore MeSH Database , Explore PubMed Journals
Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE301830 Atlas of Brain-Permeable Blood Proteins Links Neuroprotection to Alzheimer's Risk Genes [snRNAseq_astrocyte] July 3, 2026Contributors : Haoyue Zhou ; Jason Maynard ; Alexander J Pennacchio ; Amanda Apolonio ; Zimo Zhang ; Bella Ding ; Lei Yao ; Mina Negahban ; Janie Oberhauser ; Fionna Huang ; Yuichi Chayama ; Sahith Doddipalli ; Ning-Sum To ; Pui Shuen Wong ; Duc Duong ; Eddie Fox ; Nicholas Seyfried ; Tom Cheung ; Tara E Tracy ; Al Burlingame ; Andrew C YangSeries Type : Exp […]
- GSE301828 Atlas of Brain-Permeable Blood Proteins Links Neuroprotection to Alzheimer's Risk Genes [bulk_RNAseq_astrocyte] July 3, 2026Contributors : Haoyue Zhou ; Jason Maynard ; Alexander J Pennacchio ; Amanda Apolonio ; Zimo Zhang ; Bella Ding ; Lei Yao ; Mina Negahban ; Janie Oberhauser ; Fionna Huang ; Yuichi Chayama ; Sahith Doddipalli ; Ning-Sum To ; Pui Shuen Wong ; Duc Duong ; Eddie Fox ; Nicholas Seyfried ; Tom Cheung ; Tara E Tracy ; Al Burlingame ; Andrew C YangSeries Type : Exp […]
- GSE337334 Transcriptome profiling of ARHGAP29-depleted human embryonic palatal mesenchymal cells July 3, 2026Contributors : Zhumin Wang ; Ying Yang ; Lili Yu ; Chen Hu ; Wen Dong ; Di Yan ; Yongqing Huang ; Xiaoli Ma ; Jian MaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensARHGAP29 is implicated in nonsyndromic cleft lip with or without cleft palate, but its role in human palatal mesenchymal cells remains incompletely understo […]
- GSE301832 Atlas of Brain-Permeable Blood Proteins Links Neuroprotection to Alzheimer's Risk Genes [snRNAseq_microglia] July 3, 2026Contributors : Haoyue Zhou ; Jason Maynard ; Alexander J Pennacchio ; Amanda Apolonio ; Zimo Zhang ; Bella Ding ; Lei Yao ; Mina Negahban ; Janie Oberhauser ; Fionna Huang ; Yuichi Chayama ; Sahith Doddipalli ; Ning-Sum To ; Pui Shuen Wong ; Duc Duong ; Eddie Fox ; Nicholas Seyfried ; Tom Cheung ; Tara E Tracy ; Al Burlingame ; Andrew C YangSeries Type : Exp […]
- GSE294323 Thyroid cancer-associated EZH1 Q571R mutation drives chromatin compaction and H3K27me3 invasion into active chromatin July 3, 2026Contributors : Hanbyeol Kim ; Chul-Hwan LeeSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensDysregulation of Polycomb Repressive Complex 2 (PRC2) contributes to cancer. Of its catalytic subunits, Enhancer of Zeste (EZH) 1 and EZH2, EZH2 mutations are extensively studied, but the role of EZH1 in cancer remai […]
- GSE294320 Thyroid cancer-associated EZH1 Q571R mutation drives chromatin compaction and H3K27me3 invasion into active chromatin July 3, 2026Contributors : Hanbyeol Kim ; Chul-Hwan LeeSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensDysregulation of Polycomb Repressive Complex 2 (PRC2) contributes to cancer. Of its catalytic subunits, Enhancer of Zeste (EZH) 1 and EZH2, EZH2 mutations are extensively studied, but the role of EZH1 in cancer remai […]
- GSE336823 Dysregulated thymus-ovary axis promotes virtual memory T cell polarization to aggravate PCOS pathology [scRNAseq-human] July 3, 2026Contributors : Yaruo Qiu ; Weixuan Wang ; Chenlei Xu ; Yao Feng ; Dan LvSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Homo sapiensPolycystic ovary syndrome (PCOS) is characterized by androgen excess, ovarian dysfunction and polycystic ovarian morphology and is classically considered as a disorder of the hypothalamic-pitui […]
- GSE301594 Single-cell sequencing revealed the recurrence causes of ETV6::RUNX1 fusion-positive B-ALL in children July 3, 2026Contributors : Guotao Guan ; Xiuxiu Wang ; Xiuxin Li ; Qi Wang ; Xiuli Li ; Xiaojun Sun ; Liying Liu ; Yunfeng Lu ; Bingju Liu ; Xinyu Li ; Ping Zhao ; Fei Gao ; Lijun Chen ; Lihua Zhao ; Yunpeng DaiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensObjective: The ETV6::RUNX1 fusion is the most common genetic abnormality i […]
- GSE336897 Effect of peripheral kappa-opioid receptor agonists on murine T cells July 3, 2026Contributors : Katharina Hoffmann ; Karin LoserSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThis study investigated the transcriptional responses of murine T cell subsets to treatment with novel peripherally restricted, perhydroquinoxaline-derived kappa opioid receptor (KOR) agonists. We sorted and polarized primary […]
- GSE336843 DOT1L is essential for corneal epithelial identity and homeostasis July 3, 2026Contributors : Lexin Yang ; Tongxin He ; Chenghao Xuan ; Yang YangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe corneal epithelium is maintained by limbal stem cells (LSCs) that differentiate into mature epithelial cells to ensure transparency and barrier function. Epigenetic regulation is critical for corneal hom […]
- GSE336955 Phenotypic CRISPR screening identifies ZBTB10 as a novel regulator of human trophoblast differentiation [ChIP-Seq] July 3, 2026Contributors : Meagan N Esbin ; Madeleine Craske ; Rituja Bhowmik ; Xavier Darzacq ; Robert TjianSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensThe human placenta is built by trophoblast cells that fuse together, secrete hormones, and invade the uterus, and defects in these processes contribute to pregnan […]
- GSE336958 Phenotypic CRISPR screening identifies ZBTB10 as a novel regulator of human trophoblast differentiation [RNA-Seq BeWo] July 3, 2026Contributors : Meagan N Esbin ; Rituja Bhowmik ; Xavier Darzacq ; Robert TjianSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe human placenta is built by trophoblast cells that fuse together, secrete hormones, and invade the uterus, and defects in these processes contribute to pregnancy disorders such as preeclampsia […]
- GSE336960 Phenotypic CRISPR screening identifies ZBTB10 as a novel regulator of human trophoblast differentiation July 3, 2026Contributors : Meagan N Esbin ; Min YangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe human placenta is built by trophoblast cells that fuse together, secrete hormones, and invade the uterus, and defects in these processes contribute to pregnancy disorders such as preeclampsia. Because cell-cell fusion and hormone […]
- GSE301825 Atlas of Brain-Permeable Blood Proteins Links Neuroprotection to Alzheimer's Risk Genes [bulk_RNAseq_astrocyte_AD] July 3, 2026Contributors : Haoyue Zhou ; Jason Maynard ; Alexander J Pennacchio ; Amanda Apolonio ; Zimo Zhang ; Bella Ding ; Lei Yao ; Mina Negahban ; Janie Oberhauser ; Fionna Huang ; Yuichi Chayama ; Sahith Doddipalli ; Ning-Sum To ; Pui Shuen Wong ; Duc Duong ; Eddie Fox ; Nicholas Seyfried ; Tom Cheung ; Tara E Tracy ; Al Burlingame ; Andrew C YangSeries Type : Exp […]
- GSE336822 Dysregulated thymus-ovary axis promotes virtual memory T cell polarization to aggravate PCOS pathology [scRNAseq-mouse] July 3, 2026Contributors : Yaruo Qiu ; Weixuan Wang ; Chenlei Xu ; Yao Feng ; Dan LvSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Mus musculusPolycystic ovary syndrome (PCOS) is characterized by androgen excess, ovarian dysfunction and polycystic ovarian morphology and is classically considered as a disorder of the hypothalamic-pitui […]