Author: Editor

Gene Expression Omnibus Announcements & Study Releases

Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.

• GSE267738 Gene expression profile of various brain cells obtained from APP-KI mice May 3, 2026
  Contributors : Ruedl Christiane ; Wu Xiaoting ; Miller James ASeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBrain cells, such as, oligodendrocytes, and neurons, interact with each other to maintain brain homeostasis. Here, we utilize scRNAseq to investigate the significant phenotypic heterogeneity of different brain c […]
• GSE250248 RNA-seq analysis of tumor-infiltrating effector T cells isolated from subcutaneous mouse Lewis lung carcinoma (LLC) tumors May 3, 2026
  Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe goal of this study was to analyze differences in gene expression between tumor-infiltrating effector T cells with higher or lower uptake of the 2-deoxyglucose analog 2-NBDG in vivo. Mice bearing subcutaneous LLC tumors were injected intravenously with the 2-deoxyglucos […]
• GSE276541 Effect of TRIB3 overexpressing on the gene expression in NCM460 cells May 3, 2026
  Contributors : Shuang Shang ; Jing Liu ; Fang HuaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensInflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), is a chronic and relapsing disorder with increased prevalence all over the world. Bile acids are small molecules synthesized from […]
• GSE274672 Transcriptomic profile of patient derived glioblastoma stem cells from recurrent and newly diagnosed background May 3, 2026
  Contributors : S Sarkar ; A Ashokan ; B Surnar ; D G Eichberg ; T I Slepak ; M E Ivan ; S DharSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensMetabolic rewiring of neoplastic cells can fuel tumorigenicity of cancer stem cells contributing to tumor recurrence. One such cancer is glioblastoma for which tumor recurrence is […]
• GSE298713 Effect of co-culture with ETBF in NOZ cell line on gene expreesion difference May 3, 2026
  Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensEnterotoxigenic bacteroides fragilis (ETBF), a strain of B.fragilis is enriched in gallbladder cancer (GBC), but its causative role and translational implications in GBC remain unclear. Here, we demonstrate that ETBF promotes GBC cell proliferation and metastasis both in v […]
• GSE297032 Atopic asthma lowers nasal mucosal sphingolipids May 3, 2026
  Contributors : Zenna Solomon ; Rika Gomi ; Zoe Verzani ; Andrea Heras ; Perdita Permaul ; Uthra Balaji ; Jinghua Gu ; Sarah Brown ; Natalia Huerta ; Natalie Gosnell ; Paul Christos ; Jennie G Ono ; Tilla S Worgall ; Stefan WorgallSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensGenetic variations at the 17q21 asthma-risk […]
• GSE319204 scRNA analysis of inflamed and uninflamed colon tissues of Crohn's disease patients May 3, 2026
  Contributor : Jie ZhaoSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensSingle-cell RNA sequencing was performed on colonic tissues from Crohn’s disease patients, comparing inflammatory and non-inflammatory regions. The dataset characterizes cell-type composition and inflammation-associated transcriptional changes at sing […]
• GSE318527 Effect of CST3 knockout on gene expression in THP-1-derived macrophages May 3, 2026
  Contributor : Jie ZhaoSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo systematically investigate the biological role of CST3 in macrophages, we performed RNA-seq on THP-1-derived macrophages from wildtype (CST3+/+) and CST3 knockout (CST3-/-) backgrounds. Comparative transcriptomic analysis revealed differential expr […]
• GSE329021 Bulk RNA-seq of head tissue from wild-type and twist mutant Nematostella vectensis May 3, 2026
  Contributors : Patricio Ferrer Muguia ; Ulrich TechnauSeries Type : Expression profiling by high throughput sequencingOrganism : Nematostella vectensisThe basic helix-loop-helix transcription factor Twist plays roles in mesodermal development and tissue morphogenesis. To assess transcriptional changes associated with loss of Twist function, we performed bulk […]
• GSE329247 SMART-seq profiling of the ascending aorta and aortic arch from male and female Wnt1-Cre;Rosa26-mTmG mice May 3, 2026
  Contributors : Qing Lyu ; Yanzhi Wang ; Cheng Luo ; Songmao WangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusVascular smooth muscle cells (VSMCs) in the ascending aorta and aortic arch arise from two distinct embryonic origins: the second heart field (SHF) and the cardiac neural crest (CNC). Whether these populations […]
• GSE329317 Adaptive Hypothesis Testing of Body Color Polymorphism in Rana dybowskii: From Behavior to Transcription May 3, 2026
  Contributors : Yicheng Duan ; Zhiyu Guo ; Jiajun Zhang ; Yinzi YeSeries Type : Expression profiling by high throughput sequencingOrganism : Rana dybowskiiTo explore the adaptive mechanisms and molecular basis of body color polymorphism in Rana dybowskii, we conducted body color plasticity experiments, color plate preference behavioral experiments, COI gene-b […]
• GSE329398 CD109 is dynamically expressed in endothelial and endocardial subpopulations during heart development, modulates endothelial cell behavior in vitro, but is not required for cardiovascular morphogenesis May 3, 2026
  Contributors : Andrew B Harvey ; Jeremy L Barth ; Andy WesselsSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCD109 encodes a GPI-linked glycoprotein that acts as a signaling modulator in the TGF-β pathway. CD109 has emerged in several genome-wide association studies as linked to coronary artery disease, myocardial infa […]
• GSE329456 Exosomal lncRNA Microarray Profiling May 3, 2026
  Contributor : Ye ChenSeries Type : Non-coding RNA profiling by arrayOrganism : Homo sapiensExosomes were isolated from the culture supernatants of lymphocytes in two groups, and lncRNAs within the exosomes were identified using microarray sequencing.