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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE305118 Pro-inflammatory role of granzyme K producing bystander CD8 T cells in acute myeloid leukemia August 10, 2026Contributors : Lisa Aziez ; Nicolas Deredec ; Ismael Boussaid ; Carolyn G Shasha ; Romain Vazquez ; Chloé Friedrich ; Ania Alik ; Kanchanadevi Manasse ; Zoé Fremont-Debaene ; Alexandra Barthelemy ; Cyril Catelain ; Philippe Rameau ; Marguerite Vignon ; Justine Decroocq ; Olivier Kosmider ; Dorothée Selimoglu-Buet ; Evan W Newell ; Eric Solary ; François Delh […]
- GSE327833 An engineered bovine mesenchymal stem cell platform enables scalable cultivated meat production August 10, 2026Contributors : Ivana Ribarski-Chorev ; Sharon Schlesinger ; Shadi Tawil ; Ilana Vainshtein ; Dafna Shpatz ; Yael Gilad ; Eran Lavi ; Adar Kfir ; Ilan Brajzblat ; Jonathan Giron ; Oded ShoseyovSeries Type : Expression profiling by high throughput sequencingOrganism : Bos taurusCultivated meat production requires cell platforms that combine long-term prolifera […]
- GSE319584 Transcriptome profiling of adult zebrafish skeletal muscle at 7 days post-cryoinjury August 10, 2026Contributors : Snezana Kojic ; Mirjana Novkovic ; Andjela Milicevic ; Emilija Milosevic ; Jovana JasnicSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioSkeletal muscle regeneration is a complex, multistep process involving coordinated activation of injury responses, tissue remodeling, and myogenic programs. Adult zebrafis […]
- GSE336704 Nuclear GDOWN1 functions as a robust tumor suppressor by triggering premature termination and nuclear export of Pol II CTD phosphatases to facilitate RB activation (CUT&Tag) August 10, 2026Contributors : Zhanwu Zhu ; Jinjing Hu ; Wenyuan Zhu ; Yonghong Li ; Bo ChengSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensDysregulated transcription and aberrant cell cycle progression represent core cancer hallmarks, yet not many transcriptional regulators are known to simultaneously govern both pathwa […]
- GSE330748 CD4+ T cell-licensed CD8+ T cells drive immunotherapy response in MHC-I negative MMRd cancer August 10, 2026Contributors : Luciana Gneo ; David ChurchSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusDNA mismatch repair deficiency (MMRd) causes hypermutation and increased T cell response in multiple tumor types. MMRd colorectal cancers (CRC) display frequent immune evasion, but respond to immune checkpoint blockade (ICB), throu […]
- GSE256323 Characterizing the role of fibroadipogenic progenitor in experimental model of pancreatic cancer cachexia [RNASeq_KPC_KPCScr_and_miR-27a-KD] August 10, 2026Contributors : Ashok Narasimhan ; Lin W Tung ; Fabio Rossi ; Tara StachSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe experiment aims to understand the effect of miR-27a knockdown in pancreatic cancer cells and investigate if the knocking down miR-27a delays tumor progression.
- GSE342962 Transcriptomic profiling (RNA-seq) of the mid-region heart tissue from wild-type (WT) and TET2KO mice following 28 days of Angiotensin II treatment. August 10, 2026Contributors : Hashum Sum ; Alison BrewerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusChronic Angiotensin II (Ang II) infusion is a known inducer of cardiac remodeling, hypertrophy, and fibrosis, processes that are intricately linked to endothelial dysfunction. To determine how endothelial-specific deletion of TET2 a […]
- GSE342662 Acetate, a short-chain fatty acid, inhibits Coxiella burnetii replication via direct bacteriostatic effect and through vacuolar modulation and host cell perturbations. August 10, 2026Contributors : Dhritiman Samanta ; Yazen Germukly ; Brooke Hall ; Alexandria Quinonez SandelinSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCoxiella burnetii, the etiologic agent of Q fever, is an obligate intracellular pathogen that replicates within a specialized acidic compartment termed the Coxiella-containing vac […]
- GSE342601 Jellyfish-Derived Peptide Hydrolysate Alleviates Diet-Induced Obesity in Mice and Improves Aging-Related Healthspan in Caenorhabditis elegans August 10, 2026Contributors : Xiaoyu Wang ; Zhou PengSeries Type : Expression profiling by high throughput sequencingOrganism : Caenorhabditis elegansTo Investiage th cooperative gene expression of peptide treated or untreated Caenorhabditis elegans
- GSE342674 Suppressing phosphatidylserine externalization overcomes cancer immune evasion and enhances immunotherapy August 10, 2026Contributors : Johann S Bergholz ; Grace Trombley ; Gwendolyn Cusing ; Zhaoqi Li ; Margaret E Torrence ; Geneva Sganga ; Jennifer Casey ; Shangtao Liu ; Ashley H Choi ; Samuel R Meier ; Tenzing Khendu ; Yi Yu ; Teng Teng ; Binzhang Shen ; Hannah Stowe ; Salam Shaaban ; Jannik N Andersen ; Serge GueroussovSeries Type : OtherOrganism : Homo sapiens ; Mus muscu […]
- GSE342671 Longitudinal single-cell and spatial transcriptomics reveals intratumor heterogeneity, therapeutic response, and comparative value of canine marginal zone lymphoma August 10, 2026Contributors : Grace E Walker ; Marissa Macchietto ; Kelly Reid ; Lauren E Burt ; Amber Winter ; Sara Pracht ; Michelle Buettner ; Velia Penza ; Caitlin Yung ; Rose Dicovitsky ; Alana Kuzmik ; Daniel A Vallera ; Kim Demos-Davies ; Davis M Seelig ; Antonella Borgatti ; Mike Henson ; Caitlin Feiock ; Jaime F Modiano ; Shruthi Naik ; Aaron L Sarver ; Amy E Tree […]
- GSE342695 Sunitinib Induces Macrophage Dysfunction and Impaired Tissue Regeneration Through Suppression of PPARγ August 10, 2026Contributors : Zhouchen Zhang ; Qiao Qiao ; Jiannan Li ; Qingxiang Li ; Yuanning Yang ; Ying Zhou ; Hongyuan HuangSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioSunitinib, a widely used multi-target tyrosine kinase inhibitor, has side effects that Q6 may impact tissue repair and regeneration, potentially contributing to […]
- GSE342748 EZH2 inhibitor GSK126 promotes human iPSC hematopoietic differentiation August 10, 2026Contributors : Jianyi Ding ; Andre LarochelleSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe de novo generation of human hematopoietic stem cells (HSCs) from induced pluripotent stem cells (iPSCs) represents a promising avenue for the cellular therapy of blood disorders. However, existing protocols often result in t […]
- GSE342961 Transcriptomic profiling (RNA-seq) of lung endothelial cells from wild-type (WT) and TET2KO mice following 28 days of Angiotensin II treatment. August 10, 2026Contributors : Hashum Sum ; Alison BrewerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusChronic hypertension and Angiotensin II infusion induce systemic vascular and endothelial dysfunction. To investigate cell-autonomous transcriptional changes resulting from endothelial-specific TET2 deficiency in the pulmonary micro […]
- GSE301769 Dysregulated Proline Metabolism Contributes to Subretinal Fibrosis in Neovascular AMD: Therapeutic Potential of Prolyl-4-Hydroxylase Inhibition August 10, 2026Contributors : Yue Zeng ; Ting Zhang ; Elisa Cornish ; So-Ra Lee ; Michelle Yam ; Mark Eminhizer ; Jingwen Zeng ; Jialing Zhang ; Shaoxue Zeng ; Xian Wei ; Jinliang Yang ; Meidong Zhu ; Andrew Chang ; Meixia Zhang ; Jianhai Du ; Ling Zhu ; Mark C. GilliesSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSubretinal fibrosi […]