Author: Editor

Gene Expression Omnibus Announcements & Study Releases

Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.

• GSE296887 A Novel Therapeutic Agent: Harnessing Macrophage Polarization to Combat Sepsis and Alleviate Lung Injury May 12, 2026
  Contributors : Gaofei Wei ; Wenhui WangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSepsis is a complex syndrome characterized by dysregulated immune responses, with macrophage polarization being pivotal in its immunomodulation. Lung injury is a prevalent and severe consequence in sepsis. This research delved into th […]
• GSE295456 Chronic lymphocytic leukemia with IGH::BCL3-translocation is characterized by a homogenous and distinct genetic and epigenetic landscape May 12, 2026
  Contributors : Cosima Drewes ; Reiner SiebertSeries Type : Methylation profiling by genome tiling arrayOrganism : Homo sapiensApproximately 1% of chronic lymphocytic leukemia (CLL) cases harbor a translocation juxtaposing the immunoglobulin heavy chain (IGH) and B-cell lymphoma 3 (BCL3) loci. Aiming at comprehensive molecular characterization of IGH::BCL3-po […]
• GSE304521 SEX-DEPENDENT TYPE I INTERFERON SIGNALING EXACERBATES ALZHEIMER'S PATHOLOGY May 12, 2026
  Contributors : Gerard Iniesta ; Marina Guillot ; Verónica López ; Jose P López-AtalayaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusAlzheimer’s disease (AD) disproportionately affects women, but the biological basis for this sex difference remains unclear. Using transcriptomic profiling of postmortem human AD brain ti […]
• GSE304460 Replication-independent eviction of H2B.8 reveals large-scale chromatin reprogramming during seed imbibition [Hi-C] May 12, 2026
  Contributors : Lauriane Simon ; Stefania Paltrinieri ; Manon Verdier ; Qingyi Wang ; Sylviane Cotterell ; David Latrasse ; Aude Maugarny-Calès ; Gilles Sireta ; Sophie Desset ; Simon Amiard ; Christophe Bailly ; Kentaru Tamura ; Moussa Benhamed ; Christophe Tatout ; Samuel Le Goff ; Aline ProbstSeries Type : OtherOrganism : Arabidopsis thalianaThe transition […]
• GSE316165 ZNF384-Driven WTAP Transactivation Promotes H. pylori-Induced Gastric Carcinogenesis via m6A-Mediated Stabilization of PFKP and Glycolytic Flux May 12, 2026
  Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensHGC-27 GC cells were stimulated with Helicobacter pylori. RNA-seq was performed to identify diffferentially-expressed gene in Hp-infected gastric cancers.
• GSE313051 Positively charged Ce-doped polypyrrole nanoparticles ameliorate acute kidney injury by endo-exogenous regulation of oxidative stress May 12, 2026
  Contributors : Mengjie Huang ; Tuo Xiao ; Peng Qi ; Jing HaoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusAcute kidney injury (AKI) remains a critical clinical challenge with rapid renal function decline and limited therapeutic options. Mitochondrial reactive oxygen species (ROS)-induced oxidative stress drives AKI pr […]
• GSE330245 GATA4 loss promotes mutant Kras-driven pancreatic ductal adenocarcinoma in the absence of canonical precursor lesions [Epithelial RNA-seq] May 12, 2026
  Contributors : Francesc Madriles ; Mónica P. de Andrés ; Mikhail Chesnokov ; Jaime Martinez de Villarreal ; Francisco X. RealSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusGATA6 and GATA4 play key roles in pancreatic development and are essential to maintain the classical transcriptional program in pancreatic ductal ad […]
• GSE232729 A mechanistic study on the interaction effects between legacy and pollutants of emerging concern: A case study with B[a]P and diclofenac May 12, 2026
  Contributors : Carla Martins ; Lara Carvalho ; Inês Moutinho Cabral ; Leonor Saúde ; Kristian Dreij ; Pedro M CostaSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioTranscriptome profiling of whole body of Danio rerio embryos (48hpf), exposed to several treatments. The present work aims primarily at investigating a possibl […]
• GSE330256 Tumor-derived miR200a inhibits metastasis via Wnt5a/IL-6/B7-H4 axis in ovarian cancer [RNA-seq] May 12, 2026
  Contributors : He Fei ; Lina Yang ; Fengyin JiangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensGene expression analysis in human Ovarian Cancer cells(HEY) treated with gain of function of miR200a.
• GSE330249 GATA4 loss promotes mutant Kras-driven pancreatic ductal adenocarcinoma in the absence of canonical precursor lesions [ChIP-Seq] May 12, 2026
  Contributors : Francesc Madriles ; Mónica P. de Andrés ; Mikhail Chesnokov ; Jaime Martinez de Villarreal ; Francisco X. RealSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusGATA6 and GATA4 play key roles in pancreatic development and are essential to maintain the classical transcriptional program in pancre […]
• GSE330325 Epic Methylation analysis on Glycogen Storage Disorder type 1a and Healthy Controls fibroblasts May 12, 2026
  Contributors : Uri Sprecher ; Noam MוuchtarSeries Type : Methylation profiling by genome tiling arrayOrganism : Homo sapiensAn analysis of differences in the genomic methylation pattern between GSD1a and HC samples using the Illumina EPIC V2 array as shown in the Disease-associated programming of cell memory in glycogen storage disorder type 1a manuscript. T […]
• GSE330329 Xenophagocytosis blockade enhances interspecies chimerism May 12, 2026
  Contributors : Sicong Wang ; Kouta Niizuma ; Daniel D Liu ; Fabian P Suchy ; Alyssa H Chang ; Saman Tabatabaee ; Hideyuki Sato ; Ayaka Yanagida ; Hideki Masaki ; Nathan Hidajat ; Shota Homma ; Masashi Miyauchi ; Joydeep Bhadury ; Carsten T Charlesworth ; Jinyu Zhang ; Irving L Weissman ; Hiromitsu NakauchiSeries Type : Expression profiling by high throughput […]
• GSE330586 Comparative transcriptomics of luminescent and low-luminescent states in Photobacterium kishitanii ANT-2200 May 12, 2026
  Contributors : Capucine Le Cam Ligier ; Gwénola Simon ; Charlotte Berthelier ; Corinne Valette ; Elisa Lefeuvre ; Marc Gare ; Casalot LaurieSeries Type : Expression profiling by high throughput sequencingOrganism : Photobacterium kishitaniiRNA-seq was performed to compare gene expression profiles between luminescent and low-luminescent states of Photobacteri […]
• GSE293304 Regulation of endothelial cell chromatin availability and transcription factor activity in arterial-venous specification - HUVEC FUCCI RNAseq May 12, 2026
  Contributors : Chavkin W Nicholas ; Hirschi K KarenSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensArterial-venous specification of endothelial cells during vascular development requires coordination between intracellular signaling, cell cycle state, and transcription factor activity. However, the intrinsic regulatory m […]
• GSE330243 GATA4 loss promotes mutant Kras-driven pancreatic ductal adenocarcinoma in the absence of canonical precursor lesions [bulk RNA-Seq] May 12, 2026
  Contributors : Madriles Francesc ; P. de Andrés Mónica ; Chesnokov Mikhail ; Martinez de Villarreal Jaime ; Real Francisco X.Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusGATA6 and GATA4 play key roles in pancreatic development and are essential to maintain the classical transcriptional program in pancreatic ductal ad […]