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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE192986 Transcriptome Analysis with Human Vascular smooth muscle cells under 2D and 3D cell culture conditions January 4, 2025Contributors : Jiang Liu ; Peng Liu ; Lijun Fang ; Xichun Wang ; Shilong Zhong ; Yueheng Wu ; Zibei Feng ; Zhanyi LinSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe current objectives are to use of transcriptome sequencing analysis technology comprehensively understand the potential molecular mechanisms between vasc […]
- GSE252589 TrkA^WT;NOD-Scid and TrkA^F592A;NOD-Scid xenograft osteosarcoma (orthotopic) implants at 12 d post-143B OS cell innoculation for scRNA-Seq. January 4, 2025Contributors : Sowmya Ramesh ; Zhao Li ; Qizhi Qin ; Aaron JamesSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBone pain is a presenting feature of osteosarcoma (OS) mediated by skeletal-innervating peripheral afferent neurons. Potential regulatory roles of skeletal-innervating neurons in OS beyond pain sensation are u […]
- GSE251643 Elucidation and Engineering of Sphingolipid Biosynthesis Pathway inYarrowia lipolyticaforProduction of Sphingoid Bases and Glycosylceramides January 4, 2025Contributors : Seo H Shin ; Hye Y Moon ; Hae E Park ; Hyun A KangSeries Type : Expression profiling by high throughput sequencingOrganism : Yarrowia lipolyticaThis study focused on understanding and modifying the sphingolipid biosynthesis pathway in the yeast Yarrowia lipolytica. By altering specific biological processes within the yeast, the creation of new […]
- GSE281318 Wild type and tumor-derived mutant p53 share a non-canonical mode of gene occupancy [RNA-seq] January 4, 2025Contributors : M J Campbell ; J J ManfrediSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo directly examine the interplay between mutant p53 or Mdm2 and wild type p53 in gene occupancy and expression, an integrated RNA-seq and ChIP-seq analysis was performed in vivo using isogenically matched mouse strains. Response t […]
- GSE255751 Multipronged impact of environmental temperature on Staphylococcus aureus infection by phage Kayvirus rodi: Implications for biofilm control January 4, 2025Contributors : Lucía Fernández ; Ana C Duarte ; Andrea Jurado ; Laura Bueres ; Ana Rodriguez ; Pilar GarciaSeries Type : Expression profiling by high throughput sequencingOrganism : Staphylococcus aureusEnvironmental cues sometimes have a direct impact on phage particle stability, as well as bacterial physiology and metabolism, having a profound effect on ph […]
- GSE281319 Wild type and tumor-derived mutant p53 share a non-canonical mode of gene occupancy [ChIP-seq] January 4, 2025Contributors : M J Campbell ; J J ManfrediSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusTo directly examine the interplay between mutant p53 or Mdm2 and wild type p53 in gene occupancy and expression, an integrated RNA-seq and ChIP-seq analysis was performed in vivo using isogenically matched mouse strai […]
- GSE285064 The SinR•SlrR heteromer internally attenuates a long transcript of flagellar genes in B. subtilis [ChIP-seq] January 4, 2025Contributor : Ayushi MishraSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Bacillus subtilis subsp. subtilis NCIB 3610 = ATCC 6051 = DSM 10Bacillus subtilis differentiates into two cell types during growth, dictated by the activity of the alternative sigma factor SigD. The frequency of SigD-ON motile cells is increase […]
- GSE285065 The SinR•SlrR heteromer internally attenuates a long transcript of flagellar genes in B. subtilis [RNA-seq] January 4, 2025Contributor : Ayushi MishraSeries Type : Expression profiling by high throughput sequencingOrganism : Bacillus subtilis subsp. subtilis NCIB 3610 = ATCC 6051 = DSM 10Bacillus subtilis differentiates into two cell types during growth, dictated by the activity of the alternative sigma factor SigD. The frequency of SigD-ON motile cells is increased when the het […]
- GSE285743 E3 ubiquitin ligase DTX2 reinforces innate antiviral immune responses by modulating K63-linked ubiquitination of TBK1 January 4, 2025Contributors : Di Xin ; Zexing LiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTBK1 plays a pivotal role in innate antiviral immunity, serving as a critical mediator downstream of various pattern recognition receptors (PRRs). TBK1 activity is tightly regulated by post-translational modifications (PTMs) including ubiqu […]
- GSE285846 Salivary miRNA profiles in relationship with occupational stress January 4, 2025Contributors : Segio Garbarino ; Nicola Magnavita ; Barbara Pardini ; Sonia Tarallo ; Fabrizio Ciprani ; Giulio Ferrero ; Egeria Scoditti ; Alessio NaccaratiSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensWork-related stress in police officers has been recognized as a risk factor for mental and physical illness, com […]