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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE280027 Characterization of monocytes influence in human skin melanoma June 18, 2025Contributors : Alicia Nieto-Valle ; Celia Barrio-Alonso ; Alba Gutiérrez-Seijo ; Rafael Samaniego ; Paloma Sánchez-Mateos ; Elena García-MartínezSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTumor cells attract and dynamically interact with monocytes/macrophages, one of the more abundant cell types in the tumor microe […]
- GSE210798 Splenic CD169+Tim4+ Marginal Zone Metallophilic Macrophages Are Essential for Wound Healing and Resolution of Inflammation After Myocardial Infarction June 18, 2025Contributors : Mohamed A Ismahil ; Min Gao ; Gregg Rokosh ; Sumanth D PrabhuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusFidelity of wound healing after myocardial infarction (MI) is an important determinant of subsequent adverse cardiac remodeling and failure. Macrophages derived from infiltrating Ly6Chi blood monoc […]
- GSE280243 Differential Effect of Electrical stimuli on a 3D bioprinted model of inflamed skin June 18, 2025Contributors : Anna Plaksienko ; Yuanhua LiuSeries Type : Methylation profiling by genome tiling arrayOrganism : Homo sapiensTo investigate the effects of direct and alternate current on a 3D bioprinted construct containing fibroblasts and keratinocytes in a collagen matrixWe then performed gene expression profiling analysis using data obtained from RNA-seq […]
- GSE261083 Truncated NTRK2 is induced in CAP1 endothelial cells during mouse lung injury-repair June 18, 2025Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE253829 Effect of MacroD1 knockout on gene expression of heart on mouse septic model June 18, 2025Contributors : Xiaoqiang Chen ; Tianyou Yuan ; Danchuan Zheng ; Fangfang Li ; Hao Xu ; Maoqing Ye ; Shaowen Liu ; Jun LiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMetabolic plasticity of tissues determines the degree and reversibility of organ damage under inflammatory challenges. While treating septic cardiomyopat […]
- GSE275254 Transcriptomic remodeling of myeloid cells in response to maternal obesity June 18, 2025Contributors : Alina Maloyan ; Yem AlharithiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe goal of this project is to determine the effect of maternal obesity on the offspring's bone marrow CD11b+ cells gene transcriptomic profile. CD11b+ cells were isolated from the bone marrow of newly weaned mice born to hi […]
- GSE270299 RNA-seq for the soybean leaves June 18, 2025Contributors : Jiang Tian ; Cuiyue Liang ; Qi GuoSeries Type : Expression profiling by high throughput sequencingOrganism : Glycine maxTo investigate the molecular mechanism underlying the involvement of GmPAP23 in intracellular phosphorus recycling, an transcriptomic analysis was performed using the mature leaves of WT and OX5 lines grown under P sufficient […]
- GSE299500 Effects on renal senescence, copper flux and respiration during stem cell-based therapy June 18, 2025Contributors : Kating Zhuang ; Wenjuan Wang ; Guangyan CaiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusHuman umbilical cord-derived mesenchymal stem cells (hUC-MSCs) can reverse senescence after acute kidney injury (AKI) via maintaining mitochondrial homeostasis. Copper accumulation could promote senescence, but its […]
- GSE299071 Insulin-degrading enzyme regulates mRNA processing and interacts with the CCR4-NOT complex June 18, 2025Contributors : Barbara Bertocci ; Ayse Yilmaz ; Emmanuelle Waeckel-Énée ; Chiara Guerrera ; Kevin Roger ; Lamine Touré ; Peter van EndertSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusInsulin-degrading enzyme is a zinc metallo protease degrading low molecular weight substrates including insulin. Ubiquitous expression, […]
- GSE299749 Nanoplastics dysregulate macrophage function by impairing glutathione metabolism June 18, 2025Contributors : Bora Kim ; Koung-Min Park ; Haerang Lee ; Young-Min HyunSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMicro- and nanoplastics (MNPs) are emerging environmental contaminants increasingly detected in human tissues. However, how MNP-related effector mechanisms that impact the immunological function of macr […]
- GSE299553 SPIDR enables multiplexed mapping of RNA-protein interactions and uncovers a mechanism for selective translational suppression upon cell stress June 18, 2025Contributors : Erica Wolin ; Jimmy K Guo ; Mario R Blanco ; Isabel N Goronzy ; Darvesh Gorhe ; Wenzhao Dong ; Andrew A Perez ; Abdurrahman Keskin ; Elizabeth Valenzuela ; Ahmed A Abdou ; Carl R Urbinati ; Ross Kaufhold ; Tomas H Rube ; Jailson B Querido ; Mitchell Guttman ; Marko JovanovicSeries Type : OtherOrganism : Homo sapiensRNA-binding proteins (RBPs) […]
- GSE299883 A SWEET Challenge: Less Sugar for Rhizospheric Microbiome Under the Successive Wheat Cultivatoin June 18, 2025Contributors : Mehdi Rashtbari ; Lingyue Han ; Seyed S Hoseini ; Ahmad S Azimi ; Henning Kage ; Daguang Cai ; Zheng Zhou ; Bahar S RazaviSeries Type : Expression profiling by high throughput sequencingOrganism : Triticum aestivumConsidering the crucial role of root exudates, we hypothesized that continuous wheat cultivation would lead to lower glucose releas […]
- GSE299899 Epigenetic and 3D genome reprogramming during the aging of human hippocampus [CUT&Tag] June 18, 2025Contributors : Nathan R Zemke ; Seoyeon Lee ; Emily Hsu ; Bing RenSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensAge-related cognitive decline in humans is associated with altered physiology of the hippocampus, a region critical for memory consolidation and spatial navigation. While changes in gene expres […]
- GSE300009 Epigenetic profiles of response to transcranial magnetic stimulation in treatment resistant depression June 18, 2025Contributors : Jan Dahrendorff ; Monica UddinSeries Type : Methylation profiling by genome tiling arrayOrganism : Homo sapiensPeripheral blood DNA methylation was profiled in 46 patients with treatment-resistant depression prior to treatment with transcranial magnetic stimulation (TMS). Genome-wide DNA methylation was measured using the Illumina Infinium Met […]
- GSE277693 CaB34 –a spontaneously immortalized prostate cancer cell line from a Black Caribbean patient, and its radioresistant subline, as novel research models June 18, 2025Contributors : Jessica Wright ; Stephanie D White ; Stanley K Liu ; Shahbaz Khan ; Thomas KislingerSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensProstate cancer cell lines are particularly racially and clinically homogenous, and while there has been significant work in the development of additional models, few have be […]