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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE262836 Genomic characterization and transcriptomic profile of Candida krusei in a neonatal intensive care unit in Delhi, India September 18, 2025Contributors : Raju Shivarathri ; Kusum Jain ; Jianping Xu ; Anuradha Chowdhary ; Neeraj ChauhanSeries Type : Expression profiling by high throughput sequencingOrganism : Pichia kudriavzeviiIn the last decade, Candida krusei has caused multiple outbreaks of candidemia in Neonatal Intensive Care Units (NICUs) in low-and middle-income countries such as Brazil, […]
- GSE308267 Aberrant fibro-adipogenic progenitor subpopulations drive volumetric muscle loss-induced fibrosis September 18, 2025Contributors : Lauren A Hymel ; Edward A Botchwey ; Emily Greenwood ; Seul LeeSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Mus musculusVolumetric muscle loss (VML) injuries result in chronic fibrosis, inflammation, and persistent functional deficits. Fibro-adipogenic progenitor (FAP) cells are a heterogeneous, muscle-res […]
- GSE275054 Extrachromosomal DNA Associates with Nuclear Condensates and Reorganizes Chromatin Structures to Enhance Oncogenic Transcription [ChIA-PET] September 18, 2025Contributors : Harianto Tjong ; Chia-Hao Tung ; Aziz Taghbalout ; Ping Wang ; Chia-Lin WeiSeries Type : OtherOrganism : Homo sapiensExtrachromosomal, circular DNA (ecDNA) is a prevalent and significant oncogenic alteration in cancer genomes. Its frequency is associated with aggressive tumor behavior and poor patient outcome. To understand how ecDNA promotes […]
- GSE275050 Extrachromosomal DNA Associates with Nuclear Condensates and Reorganizes Chromatin Structures to Enhance Oncogenic Transcription [WGS] September 18, 2025Contributors : Harianto Tjong ; Chia-Hao Tung ; Aziz Taghbalout ; Ping Wang ; Chia-Lin WeiSeries Type : OtherOrganism : Homo sapiensExtrachromosomal, circular DNA (ecDNA) is a prevalent and significant oncogenic alteration in cancer genomes. Its frequency is associated with aggressive tumor behavior and poor patient outcome. To understand how ecDNA promotes […]
- GSE275705 Extrachromosomal DNA Associates with Nuclear Condensates and Reorganizes Chromatin Structures to Enhance Oncogenic Transcription [RNA-seq II] September 18, 2025Contributors : Harianto Tjong ; Chia-Hao Tung ; Aziz Taghbalout ; Ping Wang ; Chia-Lin WeiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensExtrachromosomal, circular DNA (ecDNA) is a prevalent and significant oncogenic alteration in cancer genomes. Its frequency is associated with aggressive tumor behavior and poor patie […]
- GSE275060 Extrachromosomal DNA Associates with Nuclear Condensates and Reorganizes Chromatin Structures to Enhance Oncogenic Transcription September 18, 2025Series Type : OtherOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
- GSE289292 Signal pathway-based culture condition improves differentiation potential of canine induced pluripotent stem cells September 18, 2025Contributors : Toshiya Nishimura ; Kyomi J IgarashiSeries Type : Expression profiling by high throughput sequencingOrganism : Canis lupus familiarisNaturally occurring diseases in companion dogs such as cancer, immune-mediated and neuro-degenerative diseases are increasingly being recognized as valuable translational disease models. While induced pluripotent […]
- GSE275722 Extrachromosomal DNA Associates with Nuclear Condensates and Reorganizes Chromatin Structures to Enhance Oncogenic Transcription [ChIP-seq] September 18, 2025Contributors : Harianto Tjong ; Chia-Hao Tung ; Aziz Taghbalout ; Ping Wang ; Chia-Lin WeiSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensExtrachromosomal, circular DNA (ecDNA) is a prevalent and significant oncogenic alteration in cancer genomes. Its frequency is associated with aggressive tumor behavior […]
- GSE297648 RNA tomography reveals spatial gene expression maps of Arabidopsis thaliana roots infected with Heterodera schachtii September 18, 2025Contributors : Anna Pijnacker ; Yuhao Wang ; Jaap-Jan Willig ; Jonas Mars ; Steffen Werner ; Kelvin Adema ; Geert Smant ; Hendrik C Korswagen ; Jose L Lozano-TorresSeries Type : OtherOrganism : Arabidopsis thalianaPlant-parastic nematodes cause substantial crop losses worldwide. The sedentary endoparasite nematode Heterodera schachtii induces specialized fee […]
- GSE296403 RNA-Seq of PBMC of FAP patient before and after a low-inflammatory diet September 18, 2025Contributors : Elena Daveri ; Giulio FerreroSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensLong-term dietary fat intake influences cancer development through metaflammation, a state of chronic low-grade inflammation driven by dysregulated lipid metabolism. Patients with Familial Adenomatous Polyposis (FAP), who carry h […]
- GSE307747 RNA sequencing of PDX-AML samples using prime-seq September 18, 2025Contributors : Irmela Jeremias ; Binje Vick ; Tobias Herold ; Wolfgang Enard ; Johannes BagnoliSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe established serially transplantable and robust, genetically engineered patient derived xenograft (PDX) models of acute myeloid leukemia (AML).
- GSE308027 Engineered Nanobodies Targeting Endogenous Digoxin-like Substances Function as Novel Immune Checkpoints Inhibitors and Enhance Immunotherapy against Cancer Metastasis September 18, 2025Contributors : Yan Chen ; Chenming Xu ; Wu YinSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusDigoxin is a well-recognized cardiovascular medication; however, epidemiological investigations have associated its clinical application with an elevated risk of malignancy. To elucidate it, we discovered, for the first time, t […]
- GSE308065 A NEW DYSTROPHIN DEFICIENT RAT MODEL MIRRORING EXON SKIPPING IN PATIENTS WITH DMD EXON 45 DELETIONS September 18, 2025Series Type : Expression profiling by high throughput sequencingOrganism : Rattus norvegicusMutations in the dystrophin (DMD) gene can cause muscle-wasting disorders ranging from the milder Becker muscular dystrophy (BMD) to the more severe Duchenne muscular dystrophy (DMD). Exon 45 deletion is the most frequently reported single-exon deletion in DMD patient […]
- GSE277433 Disrupting YAP phase separation attenuates the development of primary liver cancer in animal models September 18, 2025Contributors : Shuang-zhou Peng ; Fu-quan Jiang ; Lijun Cai ; Jia-jia LiangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusIn these murine liver cancer samples, we used specific antibody detection to find endogenous YAP formation condensates in the focal area, a phenomenon also observed in human liver cancer tissues. De […]
- GSE288381 Dicer is essential for proper maturation, composition, and function in the postnatal retina. September 18, 2025Contributors : Seoyoung Kang ; Daniel Larbi ; Eik Bruns ; Konstantin Hahne ; Mariana Lima-Carneiro ; Alireza Khodadadi-Jamayran ; Chaitra Sreenivasaiah ; Monica Andrade ; Khulan Batsuuri ; Shaoheng Chen ; Julia Jager ; Suresh Viswanathan ; Brian S Clark ; Stefanie G WohlSeries Type : Expression profiling by high throughput sequencing ; Non-coding RNA profili […]