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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE275745 Polymer Model Integrates Imaging and Epigenomics to Elucidate the Role of the Cell’s Microenvironment in Shaping 4D Chromatin Organization [RNA-Seq] March 18, 2025Contributors : Vinayak Vinayak ; Ramin Basir ; Rosela Golloshi ; Joshua Toth ; Lucas Sant’Anna ; Melike Lakadamyali ; Rachel P McCord ; Vivek B ShenoySeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensChromatin epigenetic markers have been recognized to colocalize with phase-separated genomic compartments. While the correl […]
- GSE268169 Chromatin Organization Governs Transcriptional Response and Plasticity of Cancer Stem Cells March 18, 2025Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
- GSE280315 Characterization of immune cell populations in the tumor microenvironment of colorectal cancer using high definition spatial profiling [VisiumHD] March 18, 2025Contributors : Michelli F Oliveira ; Juan P Romero ; Meii Chung ; Stephen Williams ; Andrew D Gottscho ; Anushka Gupta ; Susan E Pilipauskas ; Syrus Mohabbat ; Nandhini Raman ; David Sukovich ; David Patterson ; Sarah E TaylorSeries Type : OtherOrganism : Homo sapiensColorectal cancer (CRC) is the second-deadliest cancer in the world, yet a deeper understand […]
- GSE280311 Characterization of immune cell populations in the tumor microenvironment of colorectal cancer using high definition spatial profiling [Flex] March 18, 2025Contributors : Michelli F Oliveira ; Juan P Romero ; Meii Chung ; Stephen Williams ; Andrew D Gottscho ; Anushka Gupta ; Susan E Pilipauskas ; Syrus Mohabbat ; Nandhini Raman ; David Sukovich ; David Patterson ; Sarah E TaylorSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensColorectal cancer (CRC) is the second-deadliest […]
- GSE254470 Affinity-independent and nuclease-based strategy to profile R-loop genome-wide [HEK293T] March 18, 2025Contributors : Yaoyi Li ; Yingliang Sheng ; Hongjie YaoSeries Type : OtherOrganism : Homo sapiensR-loop is abundant triplex nucleic strand in organism, but many physiological and pathological functions remain to be fully understood, owing to a lack of robust and high-resolution methods for genome-wide detection. In this study, we develop R-loop identificatio […]
- GSE232581 Scalable production of human cortical organoids using a biocompatible polymer March 18, 2025Contributors : Yuki Miura ; Sergiu P PașcaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensSingle cell RNA-seq characterization of human induced pluripotent stem cells-derived human cortical organoids (hCO) cultured in control and XG-supplemented conditions
- GSE292163 ScRNA-seq of Small Intestine Neuroendocrine Tumors March 18, 2025Contributors : Itay Tirosh ; Einav Somech ; Debdatta Hadler ; Avishai Spitzer ; Chaya Brabolin ; Michael Tyler ; Reut Halperin ; Biton Moshe ; Amit TiroshSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensHere we profiled ten low-grade small intestine NET (SiNET) tumor samples as well as one mixed lung tumor by single-cell […]
- GSE261333 KRAS mutation-selective requirement for ACSS2 in colorectal adenoma formation. March 18, 2025Contributors : Konstantin Budagyan ; Yan Zhou ; Jonathan ChernoffSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusOncogenic KRAS mutations are prevalent in colorectal cancer (CRC) and are associated with poor prognosis and resistance to therapy. There is a substantial diversity of KRAS mutant alleles observed in CRC. Eme […]
- GSE292224 Distinct molecular mechanisms of stress habituation in the mouse hippocampus [bulk RNA-seq] March 18, 2025Contributors : Rebecca Waag ; Lukas von Ziegler ; Pierre-Luc Germain ; Johannes BohacekSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe explore how the tightly regulated molecular response triggered by acute restraint stress becomes altered after repeated restraint exposure. Transcriptomic sampling of the mouse hippoc […]
- GSE292189 Single cell and clonal analysis of AL amyloidosis plasma cells and their bone marrow microenvironment March 18, 2025Contributors : Nicolas A Gort-Freitas ; Maria Moscvin ; Benjamin Evans ; Tianzeng Chen ; Samuel Boullt ; Sean Rowell ; Srinidhi Raghav ; Antonia F Chen ; Jacob P Laubach ; Allon M Klein ; Giada BianchiSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Homo sapiensAL amyloidosis is a disorder characterized by expansion of clona […]
- GSE292225 Distinct molecular mechanisms of stress habituation in the mouse hippocampus [snATAC-seq] March 18, 2025Contributors : Rebecca Waag ; Emanuel Sonder ; Pierre-Luc Germain ; Johannes BohacekSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusWe explore how the tightly regulated molecular response triggered by acute restraint stress becomes altered after repeated restraint exposure. Transcriptomic sampling of the m […]
- GSE292231 Distinct molecular mechanisms of stress habituation in the mouse hippocampus [bulk ATAC-seq] March 18, 2025Contributors : Rebecca Waag ; Pierre-Luc Germain ; Johannes BohacekSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusWe explore how the tightly regulated molecular response triggered by acute restraint stress becomes altered after repeated restraint exposure. Transcriptomic sampling of the mouse hippocampus […]
- GSE292239 Distinct molecular mechanisms of stress habituation in the mouse hippocampus [snRNA-seq] March 18, 2025Contributors : Rebecca Waag ; Emanuel Sonder ; Pierre-Luc Germain ; Johannes BohacekSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe explore how the tightly regulated molecular response triggered by acute restraint stress becomes altered after repeated restraint exposure. Transcriptomic sampling of the mouse hippocamp […]
- GSE262791 LaminB1 DamID, RNA-seq and Genome-wide analysis of replication timing in RIF1 depleted preimplantation mouse embryos March 18, 2025Series Type : Other ; Expression profiling by high throughput sequencingOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE292044 Direct cell-to-cell transmission of retrotransposons March 18, 2025Contributors : Maya Voichek ; Andreas Bernhard ; Maria Novatchkova ; Dominik Handler ; Paul Möseneder ; Baptiste Rafanel ; Peter Duchek ; Kirsten-André Senti ; Julius BrenneckeSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Drosophila melanogasterTransposable elements are abundant in host genomes but are generally considered to […]