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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE206520 The Cdc42 effector and non-receptor tyrosine kinase, ACK defines a distinct STAT5 transcription signature in a chronic myeloid leukaemia cell model [RNA-Seq] June 21, 2025Contributors : Corry Jessica ; Daniel Jachimowicz ; Benjamin Keith ; Jose Julio Vicente-Garcia ; Helen R Mott ; Kate Wickson ; Darerca OwenSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensActivated Cdc42-associated kinase (ACK) is a Rho family effector that is widely implicated in cancer. This work investigates how ACK a […]
- GSE206524 The Cdc42 effector and non-receptor tyrosine kinase, ACK defines a distinct STAT5 transcription signature in a chronic myeloid leukaemia cell model June 21, 2025Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
- GSE206522 The Cdc42 effector and non-receptor tyrosine kinase, ACK defines a distinct STAT5 transcription signature in a chronic myeloid leukaemia cell model [CUTnRUN] June 21, 2025Contributors : Corry Jessica ; Daniel Jachimowicz ; Benjamin Keith ; Jose Julio Vicente-Garcia ; Helen R Mott ; Kate Wickson ; Darerca OwenSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensActivated Cdc42-associated kinase (ACK) is a Rho family effector that is widely implicated in cancer. This work investig […]
- GSE206827 Genome-wide maps of chromatin state in U251 cells expressing VASN. June 21, 2025Contributors : Zixi Qin ; Lihui WangSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensChromatin immunoprecipitation DNA-sequencing (ChIP-seq) for VASN in U251 cells expressing VASN.
- GSE206597 Identification of the immune enhancement effect of CpG ODN on periodontitis genetic vaccine by RNA sequencing June 21, 2025Contributors : Huijie Zhang ; Fengjiao Zeng ; Hang Yu ; Bin Chen ; Xiaohong Zhou ; Mingwei Wang ; Guohui BaiSeries Type : Expression profiling by high throughput sequencingOrganism : Rattus norvegicusPeriodontitis is one of the main causes of tooth loss in adults. Early diagnosis and intervention can effectively control the progression of periodontitis. The […]
- GSE244361 Loss of RBM45 inhibits breast cancer progression by reducing the SUMOylation of IRF7 to promote IFNB1 transcription June 21, 2025Contributors : Chaoqun Chen ; Yuesheng LvSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensType I interferons exhibit anti-proliferative and anti-cancer activities, but their regulatory mechanisms in cancer have not been fully elucidated. RNA binding proteins are master orchestrators of gene expression regulation and are […]
- GSE243085 Identification of splicing factors signature predicting prognosis risk and the mechanistic roles of novel oncogenes in HNSCC June 21, 2025Contributors : Chaoqun Chen ; Fang HuangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensHead and neck squamous cell carcinoma (HNSCC) is the most frequent subtype of head and neck cancer generally with a poor prognosis and limited treatment options due to its highly heterogeneous malignancy. In this study, we screened f […]
- GSE270006 A PLURIPOTENT STEM CELL PLATFORM FOR IN VITRO SYSTEMS GENETICS STUDIES OF MOUSE DEVELOPMENT [RNA-seq] June 21, 2025Contributors : Rachel Glenn ; Thomas Vierbuchen ; Richard P KocheSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe directed differentiation of pluripotent stem cells (PSCs) from panels of genetically diverse individuals is emerging as a powerful experimental system for characterizing the impact of natural genetic vari […]
- GSE245341 RBM25 depletion suppresses colon cancer progression through regulating alternative splicing of MNK2 June 21, 2025Contributors : Lili Zhi ; Wenjing Zhang ; Yang WangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo explore the molecular mechanism of RBM25 depletion in inhibiting colon cancer progression,we performed high-throughput mRNA sequencing (mRNA-seq) in HCT116 cells with RBM25 knockdown.
- GSE271943 Maternal Stress Triggers Early-Life Eczema via Fetal Mast Cell Reprogramming [FetalMC-bulkRNAseq] June 21, 2025Contributors : Nadine Serhan ; Nasser S Abdullah ; Nadine Gheziel ; Alexia Loste ; Rüçhan Ekren ; Elodie Labit ; Anne-Alicia Gonzalez ; Giulia Oliva ; Pauline Tarot ; Camille Petitfils ; Gaëlle Payros ; Paolo D’Avino ; Allison Voisin ; Holly Freya Grace Tinsley ; Rebecca Gentek ; Carole Brosseau ; Marie Bodinier ; Laurent Reber ; Pierre Val ; Cezmi A Akdis ; […]
- GSE270007 A PLURIPOTENT STEM CELL PLATFORM FOR IN VITRO SYSTEMS GENETICS STUDIES OF MOUSE DEVELOPMENT [ATAC-seq] June 21, 2025Contributors : Rachel Glenn ; Thomas Vierbuchen ; Richard P KocheSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusThe directed differentiation of pluripotent stem cells (PSCs) from panels of genetically diverse individuals is emerging as a powerful experimental system for characterizing the impact of natura […]
- GSE272046 Maternal Stress Triggers Early-Life Eczema via Fetal Mast Cell Reprogramming [DRG-bulkRNAseq] June 21, 2025Contributors : Nadine Serhan ; Nasser S Abdullah ; Nadine Gheziel ; Alexia Loste ; Rüçhan Ekren ; Elodie Labit ; Anne-Alicia Gonzalez ; Giulia Oliva ; Pauline Tarot ; Camille Petitfils ; Gaëlle Payros ; Paolo D’Avino ; Allison Voisin ; Holly Freya Grace Tinsley ; Rebecca Gentek ; Carole Brosseau ; Marie Bodinier ; Laurent Reber ; Pierre Val ; Cezmi A Akdis ; […]
- GSE272169 Maternal Stress Triggers Early-Life Eczema via Fetal Mast Cell Reprogramming [scRNAseq] June 21, 2025Contributors : Nadine Serhan ; Nasser S Abdullah ; Nadine Gheziel ; Alexia Loste ; Rüçhan Ekren ; Elodie Labit ; Anne-Alicia Gonzalez ; Giulia Oliva ; Pauline Tarot ; Camille Petitfls ; Gaëlle Payros ; Paolo D'Avino ; Allison Voisin ; Holly Freya Grace Tinsley ; Rebecca Gentek ; Carole Brosseau ; Marie Bodinier ; Laurent Reber ; Pierre Val ; Cezmi A Akd […]
- GSE282641 HIF1α Mediates Circadian Regulation of Skeletal Muscle Metabolism and Substrate Preference in Response to Time-of-Day Exercise June 21, 2025Contributors : Ehrlich M Amy ; MacGregor A Kirstin ; Ashcroft Stephen ; Small Lewin ; Altintas Ali ; Chibalin V Alex ; Mattanovich Matthias ; Stocks Ben ; Moritz Thomas ; Treebak T Jonas ; Zierath R JuleenSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe regulation of metabolism in peripheral tissues is mediated by pa […]
- GSE290848 Maternal Stress Triggers Early-Life Eczema via Fetal Mast Cell Reprogramming [10x Genomics Multiome ATAC + Gene Expression] June 21, 2025Contributors : Nadine Serhan ; Nasser Loste ; Nadine Ekren ; Alexia Gheziel ; Rüçhan Labit ; Elodie Labit ; Anne-Alicia Gonzalez ; Giulia Oliva ; Pauline Tarot ; Camille Petitfils ; Gaëlle Payros ; Paolo D’Avino ; Allison Voisin ; Holly Freya Grace Tinsley ; Rebecca Gentek ; Carole Brosseau ; Marie Bodinier ; Laurent Reber ; Pierre Val ; Cezmi A Akdis ; Yasu […]