Quick Links : Search PubMed , Finding Full Text , PubMed Advanced Search , Clinical Queries , Single Citation Matcher , FAQs & User Guide , Explore MeSH Database , Explore PubMed Journals
Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE295381 Altered primary somatosensory neuron development in a Pten heterozygous model for autism spectrum disorder April 27, 2026Contributors : Alejandra Fernandez ; Nick Sarn ; Charis Eng ; Kevin M WrightSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusAutism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by deficits in social interactions, repetitive behaviors, and hyper- or hyposensitivity to sensory stimuli. The […]
- GSE309912 Bulk RNA-seq Toxic Lipid-induced Epigenetic Activation of ICAM1 in Liver Sinusoidal Endothelium Regulates Myeloid-Driven Fibro-inflammatory Response in MASH April 27, 2026Contributors : Qianqian Guo ; Nantawat Satthawiwat ; Akitoshi Sano ; Chady Meroueh ; Asma Hamdi ; Xin Dai ; Khaled Warasnhe ; Alexander M Washington ; Patrick P Starlinger ; Alex Krivonos ; Sheng Cao ; Enis Kostallari ; Johan W Jonker ; Bart van de Sluis ; Feda H Hamdan ; Samar H IbahimSeries Type : Expression profiling by high throughput sequencingOrganism […]
- GSE295666 Transcriptomic insights into a GalNAc/Man-Specific lectin in yeast fermentation April 27, 2026Contributors : Changqing Tong ; Hongxin Niu ; Wei Li ; Linge LiSeries Type : Expression profiling by high throughput sequencingOrganism : Saccharomyces cerevisiaeThis study aimed to investigate the regulatory effects of Cyclina sinensis lectin (CSL) on ethanol production in Saccharomyces cerevisiae. An integrated analysis of transcriptomic and metabolomic ch […]
- GSE324160 A progeria syndrome links DNA hypermethylation to age-related pathology [mouse] April 27, 2026Contributors : Dan Sarni ; Duncan Sproul ; Andrew P JacksonSeries Type : Methylation profiling by arrayOrganism : Mus musculusDeclining tissue function and regenerative capacity underlie many chronic diseases. Experimentally establishing the mechanistic basis for such tissue ageing presents substantial challenges, given decades-long timescales and multifacto […]
- GSE314567 Age- and Tissue-dependent Diversity of Human Plasmacytoid Dendritic Cells Uncovers a Cycling Subset Dominant in Early Life and Cancer April 27, 2026Contributors : Alina Ulezko Antonova ; Patrick Rodrigues ; Marina Cella ; Marco ColonnaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPlasmacytoid dendritic cells (pDCs) are essential sentinels that rapidly produce type I interferons (IFN-I) during infection. However, most studies focus on adult blood pDCs, leaving the […]
- GSE328853 Spatial Transcriptomic Analysis of APOe3 and APOE4 Mice after Chemotherapy April 27, 2026Contributors : Olga Rodriguez ; Naazneen Khan ; Adrian Oblak ; Jeff Dage ; Chris AlbaneseSeries Type : OtherOrganism : Mus musculusSpatial transcriptomic profiling of APOE4 mice post-chemotherapy compared with APOE3 knock-in mice to assess genotype-specific regional gene expression changes.
- GSE324227 A progeria syndrome links DNA hypermethylation to age-related pathology [EM-Seq] April 27, 2026Contributors : Dan Sarni ; Duncan Sproul ; Andrew P JacksonSeries Type : Methylation profiling by high throughput sequencingOrganism : Mus musculusDeclining tissue function and regenerative capacity underlie many chronic diseases. Experimentally establishing the mechanistic basis for such tissue ageing presents substantial challenges, given decades-long time […]
- GSE324236 Progeria syndrome links DNA hypermethylation to age-related pathology April 27, 2026Series Type : Methylation profiling by array ; Methylation profiling by genome tiling arrayOrganism : Homo sapiens ; Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE324230 A progeria syndrome links DNA hypermethylation to age-related pathology [human] April 27, 2026Contributors : Dan Sarni ; Duncan Sproul ; Andrew P JacksonSeries Type : Methylation profiling by genome tiling arrayOrganism : Homo sapiensDeclining tissue function and regenerative capacity underlie many chronic diseases. Experimentally establishing the mechanistic basis for such tissue ageing presents substantial challenges, given decades-long timescales […]
- GSE328789 On the way to elucidate the effects of cannabidiol (CBD) on living organisms - assessment of changes in the global transcription profile of the spleen in a mouse model April 27, 2026Contributors : Jakub Żurowski ; Sebastian Sawicki ; Ewa Ocłoń ; Tomasz Szmatoła ; Igor Jasielczuk ; Karolina Mizera- Szpilka ; Artur GurgulSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusCannabidiol (CBD) is a phytocannabinoid that has anti-inflammatory, immunomodulatory, antioxidant, anxiolytic, antipsychotic, and anti […]
- GSE328594 LuxR regulates Flavobacterium covae pathogenesis in channel catfish (Ictalurus punctatus) April 27, 2026Contributor : Mark LilesSeries Type : Expression profiling by high throughput sequencingOrganism : Flavobacterium covaeColumnaris disease, caused by Flavobacterium covae, is one of three primary bacterial diseases that cause significant mortality and economic losses in farmed catfish (Ictalurus spp.). The quorum sensing gene luxR was reported to be upregulat […]
- GSE328796 Targeting Cyclin K-CDK12 Synergizes with ATR Inhibition by Limiting RPA Chromatin Loading in Triple-Negative Breast Cancer [ChIP-seq] April 27, 2026Contributors : Eun-Bee Choi ; Geoffrey I ShapiroSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensCyclin K-CDK12 inhibition has emerged as a promising therapeutic strategy to induce homologous recombination deficiency (HRD). However, clinical and genomic studies have not clearly linked CDK12 inactivation to […]
- GSE328838 Transcriptomic profiling reveals complement activation in chronic pancreatitis adjacent to pancreatic ductal adenocarcinoma April 27, 2026Contributors : Arun Kumar Selvam ; Ville N Pimenoff ; Mikael Björnstedt ; Joakim Dillner ; Carlos Fernández Moro ; Soledad Pouso Elduayen ; Mehran GhaderiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensShort abstract: Chronic pancreatitis (CP) and pancreatic ductal adenocarcinoma (PDAC) frequently coexist, yet distingui […]
- GSE328851 ATAD2 is a Novel Regulator of Myogenesis and Autophagy in Skeletal Muscles April 27, 2026Contributors : Sami Sedraoui ; Alaa Moamer ; Tomer J Chaffer ; Jean-Philippe Leduc-Gaudet ; Felipe Broering ; Dominique Mayaki ; Ryann Lang ; Minna Woo ; Yumin Zheng ; Jun Ding ; Marco Sandri ; Gilles Gouspillou ; Sabah HussainSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMYTHO protein is a recently described novel re […]
- GSE273852 Age- and Tissue-dependent Diversity of Human Plasmacytoid Dendritic Cells Uncovers a Cycling Subset Dominant in Early Life and Cancer April 27, 2026Contributors : Alina Ulezko Antonova ; Marco ColonnaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensPlasmacytoid dendritic cells (pDCs) are innate sentinels that produce type I interferons (IFN-I) during infection. Here, we ask how developmental stage and tissue context shape human pDC transcriptional states. Single-cel […]