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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE275946 The PIDDosome controls cardiomyocyte polyploidization during postnatal heart development January 20, 2026Contributors : Marina Leone ; Nadine Kinz ; Felix Eichin ; David Obwegs ; Valentina Sladky ; Dario Rizzotto ; Claudia Manzl ; Katharina Moos ; Etienne Jacotot ; Clarissa Savko ; Mark Sussmann ; Melanie Boerries ; Andreas VillungerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe mammalian adult heart is a post-mitotic […]
- GSE272003 TAS1440, an LSD1 Inhibitor, Disrupts the INSM1-LSD1 Complex to Activate Tumor-Suppressive Pathways via Transcriptional Reprogramming in Neuroendocrine SCLC [ChIP-seq] January 20, 2026Contributors : Takumitsu Machida ; Yingbo Gong ; Sayaka Tsukioka ; Atsushi Onodera ; Akitoshi Nakayama ; Naoko Hashimoto ; Takahiro Fuchigami ; Satoshi Yamashita ; Tatsuya Suzuki ; Ryo Hatanaka ; Yasuo Kodama ; Shuichi Ohkubo ; Tomoaki TanakaSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensSmall cell lung c […]
- GSE287075 ECD co-operates with ERBB2 to promote tumorigenesis through upregulation of unfolded protein response and glycolysis January 20, 2026Contributors : Band Vimla ; Band Hamid ; Mohapatra BhopalSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiens ; Mus musculusThe mammalian orthologue of the Drosophila ecdysoneless (ECD) mRNA and protein are overexpressed in breast cancer, and its overexpression correlates with poor prognosis and short patient survival, part […]
- GSE282126 Gene expression profile at single cell level of WT and mdig/mina53 KO MDA-MB 231 breast cancer cells January 20, 2026Contributors : Fei Chen ; Chitra ThakurSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe mineral dust-induced gene (mdig, also called as MINA or RIOX2) is upregulated in breast cancer and predicts poor overall survival of breast cancer patients. Our studies suggested the anti-metastasis feature of mdig in regulating t […]
- GSE298981 TL1A-activated Tcells as upstream regulators of perianal fistulizing disease-associated changes in the rectum of Crohn's Disease patients. January 20, 2026Contributors : Gudiño Victoria ; Cho Jae-Won ; Caballol Berta ; Corraliza Ana M ; Veny Marisol ; Dotti Isabella ; Genaro Livia M ; Sanzo-Machuca Angela ; Melón-Ardanaz Elisa ; Masamunt Carme M ; Esteller Miriam ; Teubel Iris ; Robbins Lisseth ; Giner Ángel ; Prieto Cristina ; Ferrer Elena ; Franco-Leal Raquel ; Martín-Cardona Albert ; Loras Carme ; Esteve Ma […]
- GSE291125 TL1A-activated Tcells as upstream regulators of perianal fistulizing disease-associated changes in the rectum of Crohn's Disease patients. January 20, 2026Contributors : Gudiño Victoria ; Cho Jae-Won ; Caballol Berrta ; Corraliza Ana ; Veny Marisol ; Sanzo-Machuca Ángela ; Genaro Livia ; Melón-Ardanaz Elisa ; Masamunt M Carme ; Esteller Miriam ; Fernández-Clotet Agnès ; Ordàs Ingrid ; Franco-Leal Raquel ; Ricart Elena ; Panés Julià ; Hemberg Martin ; Salas AzucenaSeries Type : Expression profiling by high thro […]
- GSE316557 Lactate-mediated cholesterol uptake promotes liver cancer progression through the SCARB1-autophagy axis January 20, 2026Contributors : Jiamin Chen ; Mingyue Zhao ; Kengcheng Liu ; Shengqi Shen ; Shi-Ting Li ; Jin Cai ; Guanxu Ji ; Linchong Sun ; Ping Gao ; Tong ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensMetabolic reprogramming supports the proliferation of cancer cells under hypoxic stress, including enhanced glycolysis and alt […]
- GSE299956 MeCP2 gene dosage-dependent neurodevelopmentally restricted defects arise by SWI/SNF-mediated aberrant activation of cell fate-determining bivalent genes [Cut & Tag] January 20, 2026Contributors : Mirko Luoni ; Michal Kubacki ; Serena Gea Giannelli ; Francesca Morosi ; Claudia Di Berardino ; Angelo Iannielli ; Alessandro Sessa ; Gaia Colasante ; Emanuele Di Patrizio Soldateschi ; Chiara Lanzuolo ; Vania BroccoliSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusIncreased dosage of genes […]
- GSE316646 Hepatocyte-specific knockout of YAP protects against atherosclerosis via inhibition of ANGPTL3 in mice January 20, 2026Contributors : Ying Hou ; Xin Zhang ; Xia Sun ; Qiaohong Qin ; Min Jia ; Xingli Su ; Yulong SuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBackground and Aims Lipid-lowering therapy is a cornerstone in the treatment of atherosclerotic cardiovascular disease (ASCVD). Although some lipid-lowering drugs have demonstrate […]
- GSE316578 Improved lipid production and transcriptomic profiling in Crypthecodinium cohnii with alternative ethanol treatment January 20, 2026Contributors : Saowarath Jantaro ; Vetaka Tharasirivat ; Nattapon PengbubphaSeries Type : Expression profiling by high throughput sequencingOrganism : Crypthecodinium cohniiIn the absence of light, the heterotrophic microalga Crypthecodinium cohnii accumulates lipids rich in docosahexaenoic acid (DHA). However, limited genetic data restricts understanding of […]
- GSE316686 Total RNA-seq of C2C12 myotubes treated with agrin or MuSK antibodies January 20, 2026Contributors : Dana L Vergoossen ; Maartje G HuijbersSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTotal RNA-seq was performed to investigate if MuSK antibody binding directly affects (NMJ) gene expression in muscle cells. C2C12 differentiated myotubes were treated for 16 hours with bivalent MuSK antibodies (activatin […]
- GSE316708 Prolonged Loss of Oxidative Phosphorylation and Mitochondrial Mass Characterize CD66b+ Leukocytes from Patients with Sepsis January 20, 2026Contributors : Christine Rodhouse ; Evan L Barrios ; Leilani Zeumer-Spataro ; Leandro Balzano-Nogueira ; Ruoxuan Wu ; Xuanxuan Yu ; Guimei Tian ; Jason O Brant ; Miguel Hernandez-Rios ; Valerie E Polcz ; Whitman Wiggins ; Angel Charles ; Marvin L Dirain ; Ricardo Ungaro ; Jaimar Rincon ; Tyler Loftus ; Feifei Xiao ; Guoshuai Cai ; Lyle L Moldawer ; Robert Ma […]
- GSE316726 BDNF engages pituitary stem cells for establishment of the adult gland and for homeostasis of the corticotrope lineage January 20, 2026Contributors : Kevin Sochodolsky ; Konstantin Khetchoumian ; Jacques DrouinSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe development and maintenance of complex organs rely on the balanced expansion of cells of different lineages to establish a functional tissue. In the pituitary gland, maintenance of the adult cor […]
- GSE223358 TFRC-RNA interactome revealed the expression and alternative splicing regulation of genes associated with IgAN in human renal tubule mesangial cells January 20, 2026Series Type : Expression profiling by high throughput sequencing ; OtherOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
- GSE316528 Inositol hexakisphosphate Functions as a Cofactor and Modulator of ADAR1 Activity January 20, 2026Contributors : Francisco Venegas-Solis ; Mengsi Lu ; Roni Cohen-Fultheim ; Felix Bender ; Valeria Fedeli ; Takuya Masunaga ; Mikako Fujita ; Thomas Zillinger ; Sabine Schneider ; Andreas Kaufmann ; Adolfo Saiardi ; Erez Y. Levanon ; Henning Jessen ; Stefan BauerSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensAdenosine-t […]