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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE285671 H3K4me3 ChIP-seq Identifies EMT-TFs in TGF-β-Induced A549 cells July 31, 2026Contributors : Minoru Terashima ; Katsuhiko Shirahige ; Ryuichiro NakatoSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensH3K4me3 marks active gene regions and broad H3K4me3 occupancy is associated with genes critical for cell identity and function. To identify novel EMT-inducing transcription factors (EMT-T […]
- GSE276725 Comparative single-cell transcriptional profiling reveals regional diversity of cell types in the human adult cerebral cortex July 31, 2026Contributors : Xiaoqun Wang ; Bo Zeng ; Qiang Ma ; Meng YangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensIn summary, our research has illustrated the cellular complexity and molecular support in specialized cortex regions, contributing to understanding cortex function and providing a resource for future studies.
- GSE298821 Diet-induced obesity affects miRNAs expression in fetal mouse liver July 31, 2026Series Type : Non-coding RNA profiling by high throughput sequencingOrganism : Mus musculusObesity during pregnancy is linked to a high risk of offspring overweight, insulin resistance, type 2 diabetes, and cardiometabolic disease in later life. However, the underlying mechanisms by which maternal factors drive these long-lasting effects remain to be fully e […]
- GSE295756 The effect of sEV/miR-29a-3p on glucose metabolism in fetal rat liver July 31, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusObesity during pregnancy is linked to a high risk of offspring overweight, insulin resistance, type 2 diabetes, and cardiometabolic disease in later life. However, the underlying mechanisms by which maternal factors drive these long-lasting effects remain to be fully eluci […]
- GSE303883 SETDB2 mitigates podocyte dysfunction in diabetic kidney disease through epigenetic silencing of SMAD3 [Kidney RNA-Seq] July 31, 2026Contributors : Lanfang Li ; Shimin Jiang ; Qi Jin ; Wenge Li ; Liang Peng ; Lihong LiuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPodocyte dysfunction represents both an early pathological hallmark and a key driver of proteinuria in diabetic kidney disease (DKD); however, the epigenetic mechanisms underlying this pr […]
- GSE300604 Study on the Effects and Mechanisms of Urea on Predation Behavior of Farmland Spiders July 31, 2026Contributors : Yang Huilin ; Huang SiqiSeries Type : Expression profiling by high throughput sequencingOrganism : Pardosa pseudoannulataCurrently, research on the impact of fertilizers on natural enemies, particularly spiders, is extremely limited. Most existing studies focus on field population dynamics and community structure, with scarce reporting on unde […]
- GSE341378 Effect of SMALS-329 treatment on gene expression in ACHN renal carcinoma cells July 31, 2026Contributors : Aidan Keith ; Vijay Ramani ; Dominique MitchellSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensLKB1 is a tumor suppressor kinase whose inactivation is associated with poor prognosis and therapeutic resistance in multiple cancer types. To investigate the transcriptional effects of pharmacological LKB1 acti […]
- GSE216985 A unique Mitochondrial Quality Control (MQC) mechanism reverses the phagosome maturation arrest caused by Mycobacterium tuberculosis July 31, 2026Contributors : Surbhi Verma ; Mrinmoy DasSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensPhagosome maturation arrest (PMA) imposed by Mycobacterium tuberculosis (Mtb) is among the classic tools that helps Mtb evade macrophage anti-bacterial response. Here we report a unique crosstalk between mitochondrial quality contro […]
- GSE341436 Characterizing the tumor microenvironment at the single-cell level reveals the potential immune evasion mechanism in giant cell tumor of bone July 31, 2026Contributor : Dongyang ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensGiant cell tumor of bone (GCTB) is intermediate, locally aggressive primary bone tumor that are usually occur in long bones and typically present as lytic lesions, leading to cortical expansion or destruction with a soft-tissue component. At pre […]
- GSE341410 Single-cell RNA sequencing of knee joint synovium from mice with collagen- and antibody-induced arthritis (C&AIA) July 31, 2026Contributors : Jiexun Cai ; Jiapeng Gao ; Yunliang YaoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusRheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation, immune cell infiltration, and progressive joint destruction. Commonly used mouse models each carry practical constraints: […]
- GSE341442 Potassium restriction phenocopies caloric restriction to extend chronological lifespan in yeast July 31, 2026Contributors : Jintao Huang ; Liping Wang ; Ziyun WuSeries Type : Expression profiling by high throughput sequencingOrganism : Saccharomyces cerevisiaePotassium, as an essential cation in yeast, regulates membrane potential, enzyme activity, and nutrient sensing pathways via transporters such as Trk1/2, and is crucial for cellular and tissue function. Here, […]
- GSE341455 Skeletal muscle reprogramming of metabolic, ribosomal and developmental pathways contributes to Roux-en-Y gastric bypass-induced adaptation in women July 31, 2026Contributors : Chantal A Pileggi ; Dhanuddara Mohottalage ; Luke S Kennedy ; Majid Nikpay ; Lauren Hamilton ; Martín Roffe ; Michel N Kanaan ; Amer Jarrar ; Nicole Kolozsvari ; Dongdong Wang ; Miroslava Cuperlovic-Culf ; Tommy Alain ; Gregory R Steinberg ; Robert Dent ; Ruth McPherson ; Mary-Ellen HarperSeries Type : Expression profiling by high throughput s […]
- GSE341480 Spatiotemporal Clonal Architecture of the Newborn Mouse Forebrain July 31, 2026Contributors : Guohua Yuan ; Marilyn Steyert ; Matthew G Keefe ; Tomasz J NowakowskiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe mammalian forebrain contains diverse neural and glial cell types distributed across anatomically and functionally distinct regions, but their temporal and regional lineage relationships […]
- GSE272242 Characteriration of mitochondrial stress response in Luhmes-derived dopaminergic neurons. Identification of open chromatin regions in stress and control conditions using ATACseq July 31, 2026Contributors : Jana Heneine ; Hélène Cheval ; Philippe RavassardSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensResponsiveness of 6 days old differentiated Luhmes cells to mitochondrial stress induced by 8 hours treatment with Antimycin-A and Oligomycin analyzed by ATACseq. Enrichment analyses performed on […]
- GSE341192 Skeletal muscle reprogramming of metabolic, ribosomal and developmental pathways contributes to Roux-en-Y gastric bypass-induced adaptation in women July 31, 2026Contributors : Chantal A Pileggi ; Dhanuddara Mohottalage ; Luke S Kennedy ; Majid Nikpay ; Lauren M Hamilton ; Martín Roffe ; Michel N Kanaan ; Amer Jarrar ; Nicole Kolozsvari ; Dongdong Wang ; Miroslava Cuperlovic-Culf ; Tommy Alain ; Gregory R Steinberg ; Robert Dent ; Ruth McPherson ; Mary-Ellen HarperSeries Type : Methylation profiling by genome tiling […]