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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE114742 Next Generation Sequencing (NGS) Facilitates Quantitative Analysis of Non-silencing Control and EP300 Knockdown Transcriptomes May 11, 2026Contributors : Magnolia L Pak ; Michael R GreenSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensPurpose: The goal of this study is to identify p300-regulated genes.
- GSE330279 Fibroblast-derived CCL2 function in skin infection May 11, 2026Contributors : Tatsuya Dokoshi ; Richard L GalloSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Mus musculusThis dataset includes bulk RNA-seq, single-cell RNA-seq, and spatial transcriptomic analyses performed to investigate the role of fibroblast-derived CCL2 in cutaneous host defense against Staphylococcus aureus infecti […]
- GSE296895 Targeting PRMT9 Overcomes Venetoclax Resistance In AML By Modulation Splicing And Inhibiting Translation May 11, 2026Contributors : Li Yang ; He Xin ; Dong Haojie ; Zhang Lei ; Che Yuan ; Wang Xin ; Yadav Umesh Yadav ; Liu Meng ; Zhang Lianjun ; Ge Shuaishuai ; Wu Guohua ; Fu Yu-Hsuan ; Chen Wei ; Kuo Ya-huei ; Chen Liang ; Marcucci Guido ; Wang Shaoyuan ; Li LingSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensArginine methylation cat […]
- GSE256009 Single-cell multiomic study of zebrafish cranial neural crest [Smart-seq3] May 11, 2026Contributors : Zhiyuan Hu ; Sarah Mayes ; Tatjana Sauka-SpenglerSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioSingle-cell multiomic study of zebrafish cranial neural crest
- GSE303928 RegVelo: gene-regulatory-informed dynamics of single cells May 11, 2026Contributors : Weixu Wang ; Zhiyuan Hu ; Philipp Weiler ; Sarah Mayes ; Marius Lange ; Daniel M Fountain ; Julianna O Haug ; Jingye Wang ; Zhengyuan Xue ; Tatjana Sauka-Spengler ; Fabian J TheisSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Danio rerioRNA velocity has emerged as a popular approach for modeling cellul […]
- GSE297922 6 week old KPPC mice treated with vehicle or C-E-G for 14 days May 11, 2026Contributors : Kian-Huat Lim ; Vikas SomaniSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe pooled three KPPC mice tumors into one sample for vehicle (n=3) or C-E-G (n=3), prepared single cell suspension and performed 10X genomics scRNASeq to assess transcriptomic changes all cell populations
- GSE330070 Loss of Smad4 drives vascular malformations via c-KIT-dependent high shear stress mimicry May 11, 2026Contributors : Johannes Gahn ; Fan Wu ; Qing Zhang ; Yuxi Di ; Tanmaya Behera ; Yonggang Ren ; Zohrah Hashemi ; Kuheli Banerjee ; Julio Cordero ; Claudia Gherman ; Kornelia Andorfer ; Caroline Seebauer ; Fatemeh Mirzapour-Shafiyi ; Gergana Dobreva ; Martin A Schwartz ; Roxana OlaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo […]
- GSE327568 Study on the molecular mechanism of pod wall fiber formation using the bean pod fiber mutant (bfm) of Phaseolus vulgaris L. May 11, 2026Contributors : Kanhui Mo ; Zhuang Sun ; Guojun Feng ; Dajun Liu ; Taifeng Zhang ; Zhishan Yan ; Chang LiuSeries Type : Expression profiling by high throughput sequencingOrganism : Phaseolus vulgarisSnap bean is a widely planted legume vegetable crop in the world, with tender pods as its edible organ. In the actual production process, excessive fiber content […]
- GSE330152 Identification of novel candidate neural genes for diet-induced obesity in outbred heterogeneous stock rats May 11, 2026Contributors : Thu Le ; Teresa Mcgee ; Osborne Seshie ; Trangdai Bui ; Gina Giorgio ; Angela Beeson ; Benjamin Johnson ; Gracie Ang ; Oksana Polesskaya ; Abraham Palmer ; William Valdar ; Richard Mott ; Leah C Solberg WoodsSeries Type : Expression profiling by high throughput sequencingOrganism : Rattus norvegicusObesity is in large part a brain disease that […]
- GSE330074 Study on the Mechanism of m5C Methyltransferase NSUN3 Remodeling the Glioma Immune Microenvironment by Driving Tunneling Nanotube-Mediated Mitochondrial Transfer via tRNA Modification [RNA-Seq] May 11, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensGlioma is the most common and aggressive malignant tumor in the central nervous system, and its immunosuppressive microenvironment is closely associated with therapeutic resistance and poor prognosis. NSUN3, an m5C methyltransferase, catalyzes m5C modification on tRNA and […]
- GSE330166 Phytochemical Intervention Elicits Sex-Specific Responses in the Gut Microbiome and Transcriptome of Drosophila May 11, 2026Contributors : Litzy Y Alvarado-Mata ; Nagamani Balagurusamy ; Umesh K ReddySeries Type : Expression profiling by high throughput sequencingOrganism : Drosophila melanogasterDietary phytochemicals are plant-derived bioactive compounds that can influence host physiology and gut microbial communities. However, the structural distinctiveness of phytochemicals a […]
- GSE330231 Divergent signaling profiles in mTOR gain-of-function Smith-Kingsmore syndrome and TSC2 deficiency May 11, 2026Contributors : Curtis R Carlson ; Yang Shen ; Hongzhi He ; Erwin K Gudenschwager ; Chunya Hou ; Junfeng Ma ; Joanna C Chiu ; Andrew C LiuSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensSmith-Kingsmore syndrome (SKS) is a rare neurodevelopmental disorder caused by gain-of-function mutations in MTOR, yet whether these mut […]
- GSE330276 Suppressed cGAS-STING DNA Sensing Drives Immune Evasion in Anaplastic Thyroid Cancer May 11, 2026Contributors : Xuguang Zhu ; Manju Acharya ; Nathan Wong ; Sheue-yann ChengSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe used single-cell RNA sequencing to study the tumor immune microenvironment of thyroid tumors in a genetically engineered mouse model harboring triple mutations in Thrb1, Trp53, and Pten.
- GSE329300 Distinct temporal patterns of liver immune responses to pathogenic and non-pathogenic Entamoeba histolytica clones May 11, 2026Contributors : Helena Fehling ; Johannes Allweier ; Barbara Honecker ; Claudia Marggraff ; Michel-Ruben Glagowski ; Juliett Anders ; Hannelore Lotter ; Iris BruchhausSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusEntamoeba histolytica is a protozoan parasite that can cause severe liver disease known as amoebic liver ab […]
- GSE330067 PEDV Discontinuous Transcription Generates A Novel Subgenomic RNA to Enhance Immune Evasion and Viral Fitness May 11, 2026Contributor : Dehua LuoSeries Type : Expression profiling by high throughput sequencingOrganism : Porcine epidemic diarrhea virusDuring viral evolution, RNA viruses accumulate advantageous mutations that enhance replicative, adaptability, and evasion of host immune responses. While most studies have focused on amino acid substitutions that alter protein func […]