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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE314009 Cross-species analysis of transcriptomic response to alphaherpesvirus infection in human, bovine and equine cells January 14, 2026Contributors : Mirko Schmitz ; Eva Neugebauer ; Florian Full ; Kristen ConnSeries Type : Expression profiling by high throughput sequencingOrganism : Bos taurus ; Equus caballus ; Homo sapiensComparative transcriptomics offers a powerful approach to elucidate host–virus interactions across related pathogens, yet systematic evaluations across spe-cies-matched […]
- GSE270878 Chemotherapy-induced extracellular matrix remodelling in HGSOC January 14, 2026Contributors : Eleni Maniati ; Panoraia Kotantaki ; Florian Laforets ; Frances R BalkwillSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusIn this study we used two murine orthtotopic, transplantable synegeneic models, one that displays excellent response (60577) to carboplatin/paclitaxel and one that is highly chemoresis […]
- GSE316333 CUT&Tag profiling of JUND chromatin binding in human mast cell line LAD2 under SCF stimulation and imatinib perturbation January 14, 2026Contributors : Tianyu Cao ; Yfeng JingSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensMast cells respond to cytokine cues through rapid transcriptional rewiring. Here we generated CUT&Tag profiles of the transcription factor JUND in the human mast cell line LAD2 under three culture conditions: SCF with […]
- GSE298390 Protein C-Terminal Variations Impact Proteostasis January 14, 2026Contributors : Ching-Yu Chu ; Shu-Yu Hsu ; Hsueh-Chi S YenSeries Type : OtherOrganism : Homo sapiensProtein C-termini can vary due to errors or programmed regulation, contributing to proteome diversity, yet their impact on the proteome remains poorly understood. Although aberrant C-termini are often liked to protein degradation, it is unclear if this holds t […]
- GSE293026 REV-ERB-alpha and -beta coordinately regulate astrocyte reactivity and proteostatic function January 14, 2026Contributors : Collin J Nadarajah ; Michelle Y Li ; Ibrahim O Saliu ; Elsa I Quillin ; Kevin Boyer ; Julie M Dimitry ; Yinying (Cynthia Chen ; Melvin W King ; Jiyeon Lee ; Patrick W Sheehan ; Albert A Davis ; Mitchell A Lazar ; Guoyan Zhao ; Erik S MusiekSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe molecular circ […]
- GSE306883 Runx1 in Postn-expressing fibroblasts exacerbates adverse cardiac remodeling post myocardial infarction January 14, 2026Contributors : Kaelin A Akins ; Anooj Arkatkar ; Michael A Flinn ; Natalie Sandor ; Alexandra L Purdy ; Annabelle L Brusacoram ; Samantha K Swift ; Sydney Buday ; Priyanka Choudhury ; Miao Cui ; Brian L Lin ; Caitlin C O'Meara ; Michaela PattersonSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusRunx1 is strongly ind […]
- GSE305410 Bulk RNAseq parietal bone PND9-Isotype VS aCSF1R January 14, 2026Contributors : Rejane Rua ; Elisa Eme-Scolan ; Michel Gomes ; Oussama KassemSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBulk RNAseq of the parietal bone of C57Bl6J pups treated transcranially at post-natal days 2, 4 and 6 with control isotype or CSF1R blocking antibody to deplete myeloid cells. Pups are perfused at […]
- GSE316046 scRNA-seq data of CD8+ T cells isolated from control and DHEA-treated mice January 14, 2026Contributors : Yaruo Qiu ; Yao Feng ; Dan LvSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo determine the changes in CD8+ T cells upon DHEA treatment, we performed scRNA-seq to analyze the CD8+T cell in C57BL/6 mice subjected to DHEA induced PCOS model.
- GSE316044 Transcriptome profiles of bovine muscle stem cells cultured in serum-containing condition and small molecule–supplemented serum-free media by RNA-seq analysis January 14, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Bos taurusCultured meat, as an emerging sustainable food production technology, offers multiple advantages. However, its large-scale application still faces critical technical bottlenecks, most notably the strong reliance on fetal bovine serum (FBS). In recent years, serum-free cultur […]
- GSE316097 Heliophilum fasciatum regulation in response to available sulfate and thiosulfate concentrations. January 14, 2026Contributors : Calissa S Carlisle ; Justin A North ; Kelly S BenderSeries Type : Expression profiling by high throughput sequencingOrganism : Heliophilum fasciatumHeliophilum fasciatum is an anoxygenic photosynthetic bacteria isolated from rice soil. Previous work outlined the existence of five nitrogen-fixation-like gene clusters potentially involved in sul […]
- GSE316049 KMT2D maintains Treg homeostasis and protects against inflammatory diseases by regulating the purinergic channel P2X7 level January 14, 2026Contributor : Peng WangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusRegulatory T (Treg) cells are essential for maintaining immune homeostasis and tolerance through the prevention of inflammatory and autoimmune responses. The histone methyltransferase KMT2D is indispensable for induced Treg (iTreg) cell differentiati […]
- GSE316112 RiboBright reveals cell-type specific differences in ribosome organization and movement January 14, 2026Contributors : Georgia Poulladofonou ; Carmen Grandi ; Xinyu Hu ; Phillip Yesley ; Willem Velema ; Maike HansenSeries Type : OtherOrganism : Homo sapiensRibosomes are responsible for protein synthesis in all living systems. Determining their cellular organization, movement and translational activity is crucial for dissecting ribosomes’ complex functions. In […]
- GSE316149 Monocyte-derived IL-10 drives sex differences in pain duration January 14, 2026Contributors : Jaewon Sim ; Elizabeth O’Guin ; Chiho Sugimoto ; Sophie Laumet ; Karli Monahan ; Matthew P Bernard ; Samuel A McLean ; Liz M Albertorio-Sáez ; Ying Zhao ; Hariharan Ramakrishnan ; Sabrina de Souza ; Olivia C Eller ; Christine J Smoyer ; Kyle M Baumbauer ; Matthias Mack ; Joseph K Folger ; Alfred J Robison ; Sarah D Linnstaedt ; Geoffroy Laumet […]
- GSE316190 Targeting HMGB2 acts as dual immunomodulator by bolstering CD8+ T cell function and inhibiting tumor growth in hepatocellular carcinoma [RNA-Seq] January 14, 2026Contributors : Weifeng Qu ; Guiqi Zhu ; Yinghong ShiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTranscriptional features were detected in NC versus HMGB2-knockout CD8+ T cells of C57BL/6J mice.
- GSE312736 Transcriptomic insights into metabolic reprogramming and exo-polysaccharide synthesis in Porphyridium purpureum under gradual nitrogen deprivation January 14, 2026Contributors : Maurean Guerreiro ; Coline Emmanuel ; Céline Dupuits ; Christine Gardarin ; Said Mouzeyar ; João Varela ; Jane Roche ; Céline LarocheSeries Type : Expression profiling by high throughput sequencingOrganism : Porphyridium purpureumPorphyridium species are known red microalgae for producing valuable bioactive compounds such as sulfated exopolysa […]