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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE261077 ac4C in regulation of gene expression February 28, 2026Contributors : Pavel Kudrin ; Ankita Singh ; Ulf Andersson Vang ØromSeries Type : OtherOrganism : Homo sapiensWe have examined the location of ac4C on nuclear RNA and identified several long ncRNAs where ac4C could be important for their function.
- GSE282442 Epigenetic Memory of Intestinal Epithelial Cells in Inflammatory Bowel Disease [ATAC-seq] February 28, 2026Contributors : Brooke R Druliner ; Feda HamdanSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensThe pathogenesis of Inflammatory Bowel Disease (IBD) is a multifactorial process characterized by inflammation and damage to the intestinal barrier, which is made up of intestinal epithelial cells (IECs). Since IB […]
- GSE273952 GABA promotes resistance to immunotherapy of patients with TLS-positive tumours [Spatial Transcriptomics] February 28, 2026Contributors : Isaias Hernandez-Verdin ; Anne Calvez ; Antoine Bougoüin ; Cheng-Ming Sun ; Asmat Ullah ; Virgine Verkarre ; Yann-Alexandre Vano ; Lucile Vanhersecke ; Alban Bessede ; Jean-Philippe Guegan ; Antoine Italiano ; Stéphane Oudard ; Catherine Sautès-Fridman ; Wolf H FridmanSeries Type : OtherOrganism : Homo sapiensTertiary lymphoid structures (TLS) […]
- GSE289616 Light restores sporulation in cured Rhizopus microsporus of its endosymbionts unveilling their role in virulence February 28, 2026Contributors : Ahmiane Youssef ; Lax Carlos ; Bejar-González Sonia ; Figueras-Salvat Maria Josefa ; Capilla Javier ; Sanchís Marta ; Nicolás Francisco Esteban ; Garre VictorianoSeries Type : Expression profiling by high throughput sequencingOrganism : Rhizopus microsporusRhizopus microsporus is one of the most common agents of mucormycosis, a severe and emer […]
- GSE288895 Next Generation Sequencing Facilitates Quantitative Analysis of HAECWT and HAECSAHH-KO February 28, 2026Contributor : Si LiuSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensObjective: the next generation sequencing (NGS) has revolutionized the system-based analysis of cellular pathways. The purpose of this study was to explore the Gene expression profiling changes caused by SAHH knockout in atherosclerosis.
- GSE290739 Comparative Metabolomic and Transcriptomic Analysis of Two Dimensional and Three Dimensional Mesenchymal Stem Cell Cultures for Improved Therapeutic Applications February 28, 2026Contributors : Jee-Heon Jeong ; Joo-Won Nam ; Dongryeol Ryu ; Manju Shrestha ; Yun-seo Gil ; Yunju JoSeries Type : OtherOrganism : Mus musculusMesenchymal stem cells (MSCs) are widely used in regenerative medicine due to their multipotency and immunomodulatory capabilities. Compared to conventional two-dimensional (2D) monolayer cultures, three-dimensional ( […]
- GSE290062 The Impact of Liver Transplantation on the Expression Profile of Small RNAs in Plasma Exosomes of Patients with Respiratory Symptoms Similar to Hepatopulmonary Syndrome February 28, 2026Contributor : Yanan LiSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensThis study is centered on the alterations in the expression of small RNAs within plasma exosomes before and after liver transplantation. A subset of patients exhibited respiratory symptoms similar to hepatopulmonary syndrome prior to liver transpl […]
- GSE320266 Expression analysis in plasma sample from KRAS G12C–mutant patients monitoring during treatment with KRAS G12C inhibitors February 28, 2026Contributors : Rafael Rosell ; Ana GiménezSeries Type : Expression profiling by arrayOrganism : Homo sapiensFollow-up at baseline, 3 days, 6 weeks after the treatment of KRAS G12C mutant patients treated with KRAS G12C inhibitors in blood
- GSE319586 Quantifying the fidelity of in vitro human cell culture systems using a biomedical foundation model February 28, 2026Contributors : Scott T Espenschied ; Satoru Fujii ; Ryan J Musich ; Thaddeus S StappenbeckSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensPrimary cell culture is fast becoming a dominant method for discovery work regarding human disease. Currently there are no methods to quantitatively benchmark these systems. Here we a […]
- GSE320287 NF-κB transcriptionally perturbs p53 dynamics hampering DNA2repair. February 28, 2026Contributors : Emanuele Colombo ; Sara Pozzi ; Alessia Loffreda ; Francesca Genova ; Paola Falletta ; Erika Aloi ; Timothy Heinichen ; Alessandra Agresti ; Marco E. Bianchi ; Samuel Zambrano ; Davide MazzaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCells integrate multiple, often concurrent signals through intertwin […]
- GSE320268 Expression analysis of baseline tissue samples from KRAS G12C–mutant patients and longitudinal blood monitoring during treatment with KRAS G12C inhibitors February 28, 2026Contributors : Rafael Rosell ; Ana GiménezSeries Type : Expression profiling by arrayOrganism : Homo sapiensExpression analysis in baseline tissue samples from KRAS G12C mutant patients, follow-up of KRAS mutant patients treated with KRAS G12C inhibitors in blood and analysis of paired biopsies
- GSE320297 Transcriptome profiling of Chlamydomonas reinhardtii CreTPT10 mutants during the transition to extended darkness February 28, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Chlamydomonas reinhardtiiChloroplast phosphate translocators coordinate carbon allocation between the cytosol and plastid during heterotrophic growth. Here, RNA-seq was performed to characterize transcriptome reprogramming in Chlamydomonas reinhardtii following transfer from low light […]
- GSE320302 Early ingestive experience with a high-fat diet tunes satiation and nutrient-specific appetitive behaviors February 28, 2026Contributors : Meaghan McCoy ; Anna KamitakaharaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusOverconsumption of foods rich in fats, sugars, and calories is a major contributing factor to increased risk for cardiometabolic disease. Ingestive experience with these foods can begin early in children, yet there is limited […]
- GSE320321 Baseline NanoString IO360/BC360 expression in longitudinal midlife benign breast biopsies (ARLI pace cohort) February 28, 2026Series Type : Expression profiling by arrayOrganism : Homo sapiensBaseline lobule-enriched FFPE RNA from benign breast biopsies of women aged 45–55 was profiled using NanoString nCounter PanCancer IO 360 and Breast Cancer 360 panels. Sample identifiers were anonymized (ARLI###) for public release; the original internal block codes are retained only in a priv […]
- GSE226102 Regulation of thin shell traits by SHP based on UPRmt pathway February 28, 2026Contributor : Moyang LiuSeries Type : Expression profiling by high throughput sequencingOrganism : Arabidopsis thalianaTo produce thin shell is one of important goals in breeding, which can effectively solve the practical problems of shelling difficulty and rice broken in grain processing, as a result improves the quality and economic value of products. As a […]