Category: PubMeD- NCBI2

Gene Expression Omnibus Announcements & Study Releases

Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.

• GSE278216 SORLA upregulation suppresses global pathological effects in aged tauopathy mouse brain May 24, 2026
  Series Type : Expression profiling by high throughput sequencing ; OtherOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
• GSE298339 Reference genome assembly of Eriocheir sinensis eystalk in six tempeture conditions May 24, 2026
  Contributors : Ran Li ; Tong Hao ; Jinsheng SunSeries Type : Expression profiling by high throughput sequencingOrganism : Eriocheir sinensisReference genome was assembed for mixture sample of Eriocheir sinensis eyestalk under low tempeture (7°C,12°C,17°C) ,normal temperature (22°C) and high temperature (27°C, 32°C) conditions.The reference genome was used fo […]
• GSE297561 Comparison of the LRR domain deletion strain TOS01ΔLRR of the internalin gene and the wild type strain TOS01 of Streptococcus agalactiae May 24, 2026
  Contributors : Yinhui Peng ; Xiaohui Cai ; Xin Lu ; Ming LiuSeries Type : Expression profiling by high throughput sequencingOrganism : Streptococcus agalactiaeTOS01ΔLRR VS TOS01
• GSE314107 RNA seq - comparing ingB mutant to AF293 - Genetic mechanisms of azole tolerance May 24, 2026
  Contributors : Sandeep Vellanki ; Robert A CramerSeries Type : Expression profiling by high throughput sequencingOrganism : Aspergillus fumigatus Af293The Inhibitor of Growth domain proteins are conserved in all eukaryotes. Here we show that loss of ING domain protein (IngB) results in tolerance to azoles in vitro and in vivo. To determine the underlying mec […]
• GSE309936 mRNA expression profile of OVA-specific Th2 cells from cLNs of mice injected with or without OVA-specific IgE after nasal OVA challenge May 24, 2026
  Contributors : Takuya Nakai ; Saya Tezuka ; Yu-Chen Liu ; Daisuke Okuzaki ; Etsushi Kuroda ; Kazufumi MatsushitaSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Mus musculusTo elucidate the role of systemic antigen-specific IgE in the local activation of Th2 cells during allergic rhinitis (AR), we employed an adoptive transf […]
• GSE331442 Spatially informed learning and optimal transport reveal astrocyte morphological states decoupled from transcriptional variation in ALS May 24, 2026
  Contributors : Elisa Messori ; Doaa Taha ; Lisa Fournier ; Anna Foix Romero ; Virginie Uhlman ; Pascal Frossard ; Cédric Vincent-Cuaz ; Rickie Patani ; Raphaëlle LuisierSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensAstrocyte reactivity is increasingly recognised as a central contributor to neurological disease, yet as […]
• GSE318836 Thyroid Hormone Activation Drives Fibroblast Identity and Tumor Remodeling in Cutaneous Squamous Cell Carcinoma May 24, 2026
  Contributors : Emery Di Cicco ; Stefano Sol ; Fabiana Boncimino ; Monica Dentice ; Anna MandinovaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusCutaneous squamous cell carcinoma (cSCC) is a major cause of cancer-related mortality, with Cancer-Associated Fibroblasts (CAFs) acting as central drivers of tumor progression […]
• GSE330122 Single-cell transcriptomics and bulk T-cell receptor beta-chain sequencing of peripheral blood mononuclear cells from patients with inflammatory bowel disease (Crohn's disease and ulcerative colitis) and healthy controls I May 24, 2026
  Contributors : Joshua E Chan ; Azam Mohsin ; Jens Krijgsman ; Ciska Lindelauf ; Qinghui Mu ; Brianna Cavalla ; Xuhuai Ji ; Sarah E Streett ; Vincent van Unen ; Mark M DavisSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe profiled peripheral blood mononuclear cells (PBMCs) from patients with Crohn's disease (CD), […]
• GSE328342 Nano-enabled spatially selective protein degradation modulates lactate metabolism to potentiate antitumor immunity in liver cancer May 24, 2026
  Contributors : Jinhong Du ; Shu Han ; Rui Song ; Jianze Wang ; Linyu Zhang ; Yueyang Xu ; Haoyi Zhou ; Feng Wang ; Sen Qin ; Da Xu ; Yameng Hao ; Kui Li ; Xin Zhou ; Jiadong Wang ; Luyang Sun ; Zhi Yang ; Zhaofei LiuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusDysregulated cancer metabolism, driven in part by excessi […]
• GSE330584 A genetic program for rapid initiation of axillary meristems at the onset of flowering May 24, 2026
  Contributors : Zohar Meir ; Grace Lhaineikim ; Yuval EshedSeries Type : Expression profiling by high throughput sequencingOrganism : Solanum lycopersicumAxillary meristems arise across developmental stages and at different positions along the shoot. These meristems vary in their initiation, pausing, outgrowth dynamics and morphogenetic outcomes. We used toma […]
• GSE330123 Single-cell transcriptomics and bulk T-cell receptor beta-chain sequencing of peripheral blood mononuclear cells from patients with inflammatory bowel disease II (Crohn's disease and ulcerative colitis) and healthy controls May 24, 2026
  Contributors : Joshua E Chan ; Azam Mohsin ; Jens Krijgsman ; Ciska Lindelauf ; Qinghui Mu ; Brianna Cavalla ; Xuhuai Ji ; Sarah E Streett ; Vincent van Unen ; Mark M DavisSeries Type : OtherOrganism : Homo sapiensWe profiled peripheral blood mononuclear cells (PBMCs) from patients with Crohn's disease (CD), ulcerative colitis (UC), and healthy controls […]
• GSE331328 Transcriptomic profiling of LPS-stimulated RAW264.7 macrophages after low-intensity ultrasound treatment May 24, 2026
  Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMacrophage-mediated inflammation is a key pathological feature of the injured tendon-to-bone interface after rotator cuff tear. In this study, we performed bulk RNA sequencing to investigate the transcriptional effects of low-intensity ultrasound on inflammatory macrophage […]
• GSE331372 CYCLON is a nucleolar protein that regulates pan-cancer cell fitness through ribosome biogenesis May 24, 2026
  Contributors : Anouk Emadali ; Andrea C Garcia-Sandoval ; Emilie MontautSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTumor progression is driven by cancer cell fitness, defined as the capacity of malignant cells to maintain growth, adapt to stress and withstand therapy Cellular fitness is fundamentally governed by nu […]
• GSE331389 Lactylation of histone variant MacroH2A1 at K134 regulates osteogenic differentiation of bone marrow mesenchymal stem cells May 24, 2026
  Contributors : Jianyu Liu ; Tao Wang ; Xiaoyuan XuSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensOsteoporosis, a prevalent age-related bone disorder, stems from imbalanced osteoclast/osteoblast activity and skewed mesenchymal stem cell (MSC) lineage commitment. Although lactate is linked to osteoporosis pathogenesis, t […]
• GSE278215 SORLA upregulation suppresses global pathological effects in aged tauopathy mouse brain [snRNA-seq] May 24, 2026
  Contributors : Huijie Huang ; Timothy Y HuangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusA role for the type I transmembrane trafficking receptor SORLA in reducing Aβ levels has been well-established, however, virtually nothing is known with respect to whether and how SORLA can potentially affect tau pathology. Here […]