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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE167159 Single-cell RNA sequencing of PBMCs from convalescent COVID-19 patients compared to healthy controls July 15, 2026Contributor : Poojitha SitaramSeries Type : Expression profiling by high throughput sequencingOrganism : We compared the immune response to COVID-19 in symptomatic and asymptomatic patients when compared to healthy controls after recovery from infection. We observed active interferon signaling in symptomatic patients even after recovery.
- GSE272205 3D porous microscaffold promoted hPSC-macrophage large-scale production by facilitating proliferation and self-renewal gene network July 15, 2026Contributors : Peiliang Wang ; Hui Qiu ; Xia Chen ; Wenjing Li ; Tianjie Li ; Jie NaSeries Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Macrophages play crucial roles in various physiological and pathological processes, including immune response and tissue homeostasis. […]
- GSE237572 Sequencing of C.elegans at different time points treated with Black Rice Extract and controls July 15, 2026Contributors : Danyang Wang ; Shanshan Yu ; Chenxi LinSeries Type : Expression profiling by high throughput sequencingOrganism : Comparison of gene expression profiles from C. elegans at different time points after OP50 and Black Rice Extract (BRE) treatment. The RNA-seq data comprise 5 time points (1, 6, 11, 15 and 17 days) treated with OP50 and BRE as well […]
- GSE302308 Induction of mitochondrial DNA compaction limits innate immune memory July 15, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Implication of innate immune memory in host defense and pathogenesis of diverse inflammatory diseases is usually characterized by chromatin modification that leads to more effective transcription of cytokine genes. Mitochondrial DNA (mtDNA) is compacted by mitochondrial transcription […]
- GSE278287 Bulk RNA-seq of striatum of 6-OHDA lesioned rats exposed to levodopa/benserazide and trapidil July 15, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Gene expression changes in striatum of 6-OHDA lesioned female Sprague Dawley rats due to 14 days of daily dosing of levodopa/benserazide with or without trapidil.
- GSE316389 Chromatin accessibility and gene expression profiling of primary and metastatic ER+ breast cancer [ATAC-seq] July 15, 2026Contributors : Heredia Frances ; Maldonado Natalia ; Fogle Homer ; Kelly Michael R ; Wisniewsk Kamila ; Care Lisa A. ; Franco Hector L.Series Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : In this project, we generated a resource dataset that includes ATAC-seq and RNA-seq data from ER positive primary breast tumors and matc […]
- GSE309593 Longitudinal Analysis of Multiple Myeloma: Therapeutic Response and Immune Microenvironment Dynamics in the Context of Tumor Heterogeneity [CITE-Seq] July 15, 2026Contributors : Aishwarya Chander ; Patrick I McGrath ; Love Tätting ; Yudong D He ; Emma L Kuan ; Marla C Glass ; Samir Rachid Zaim ; Palak C Genge ; Medbh A Dillon ; Cole G Phalen ; Lauren Y Okada ; Zachary J Thomson ; Christian M LaFrance ; Tao Peng ; Peter J Wittig ; Alexander T Heubeck ; Julian Reading ; Charles R Roll ; Veronica Hernandez ; Vaishnavi Pa […]
- GSE338265 Smad4 and Eomes converge on a shared transcriptional program associated with inflammatory CD8 T-cell differentiation July 15, 2026Contributors : Karthik Chandiran ; Linda CauleySeries Type : Expression profiling by high throughput sequencingOrganism : The ability of CD8 T cells to mediate protective immunity while limiting immunopathology depends on critical transcription factors such as Smad4 and Eomes that regulate differentiation of activated CTLs. Disruption of transcriptional prog […]
- GSE338258 APOBEC3-driven attenuation of the 2022 global outbreak monkeypox virus relative to its clade IIb ancestor July 15, 2026Contributors : Rebecca P Sumner ; Lucy Eke ; Bruno Hernaez ; Alasdair J Hood ; Telma Sancheira Freitas ; Hannah Ashby ; Ailish Ellis ; Marine Petit ; Sian Lant ; Isobel Stokes ; Preetam Parija ; Isabel Alonso ; Francisco J Alvarez-de Miranda ; Alazne R Unanue ; Kevin Maringer ; Isabelle Dietrich ; Bryan Charleston ; Geoffrey L Smith ; David O Ulaeto ; Antoni […]
- GSE338304 SRPK2 CLIP-seq reveals direct RNA targets in breast cancer cells July 15, 2026Contributors : Jimeng Guan ; Linhui Zhang ; Kai Luo ; Jia Hou ; Yinzhao Chen ; Fei Wang ; Guixin ZhangSeries Type : OtherOrganism : SRPK2 (SRSF protein kinase 2) is a serine/arginine-rich protein-specific kinase that phosphorylates splicing factors and regulates alternative splicing. SRPK2 is highly expressed in breast cancer and associated with poor prognos […]
- GSE338289 Characterization of molecular changes associated with aging in the mouse cochlear lateral wall [re-analysis of GSE197634] July 15, 2026Contributors : Hainan Lang ; Jeremy L BarthSeries Type : Expression profiling by high throughput sequencingOrganism : Overall goal of the study was to identify molecular regulators that change in the cochlear lateral wall as a function of aging
- GSE338307 SRPK2 overexpression remodels the transcriptome landscape of triple-negative breast cancer cells July 15, 2026Contributors : Jimeng Guan ; Linhui Zhang ; Kai Luo ; Jia Hou ; Yinzhao Chen ; Fei Wang ; Guixin ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : SRPK2 (SRSF protein kinase 2) is a serine/arginine-rich protein-specific kinase that phosphorylates SR splicing factors and regulates pre-mRNA alternative splicing. SRPK2 is highly ex […]
- GSE338309 Dissection of Poly(A)-binding protein (PABPC) cellular function using degron-mediated depletion with replacement [Nanopore] July 15, 2026Contributors : Ryan Y Muller ; Kiara X Wang ; David P BartelSeries Type : Expression profiling by high throughput sequencingOrganism : Cytoplasmic poly(A)-binding proteins (PABPCs) are essential and highly abundant regulators of mRNA stability and translation, but their cellular functions have been difficult to dissect due to slow turnover and the lethality […]
- GSE338324 Hemin-induced DEGs in Lung, Kidney of WT and hepatic SR-BI KO mice July 15, 2026Contributors : Jianyao Xue ; XiangAn LiSeries Type : Expression profiling by high throughput sequencingOrganism : Acute hemolysis can deplete haptoglobin and hemopexin, leaving toxic free heme insufficiently controlled. Here, the authors show that scavenger receptor BI (SR-BI) mediates hepatic uptake of free heme and is essential for protection against heme- […]
- GSE338378 Deep learning design and in vivo validation of Müller glia-specific cis-regulatory elements July 15, 2026Contributors : Oriol Fornes ; Kyung Duk Koh ; Rebecca M Marton ; Jiapei Chen ; Kevin A Marroquin ; Gyeong Jin Kang ; Sören Müller ; Gokcen Eraslan ; Eliah R Shamir ; Pratiksha I Thakore ; Heinrich Jasper ; David GarfieldSeries Type : Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism […]