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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE126437 Timecourse of Chromium exposure (Bisulfite-Seq) February 14, 2026Contributors : Li Lin ; Jianlin LouSeries Type : Methylation profiling by high throughput sequencingOrganism : Homo sapiensBisulfite DNAseq was performed in a timecourse analysis of responses to Chromium exposure in LCLs
- GSE126178 Timecourse of Chromium exposure (RNA-Seq) February 14, 2026Contributors : Alan Branco ; Jianlin LouSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensRNAseq was performed in a timecourse analysis of gene expression responses to Chromium exposure in LCLs
- GSE230908 Single-Cell Profiling Across Immune Tissues and Organs Reveals Immunosenescence Signatures in Male Rhesus Monkeys February 14, 2026Contributors : Shengnan Wang ; Zhengna Zhu ; Hongju Yang ; Yaping Yan ; Luyao Ran ; Naixue Yang ; Yichao Wang ; Li Wu ; Bing Bai ; Weizhi Ji ; Wei SiSeries Type : Expression profiling by high throughput sequencingOrganism : Macaca mulattaSingle cell sequencing of rhesus monkey immune tissues and organs
- GSE126438 Timecourse of Chromium exposure February 14, 2026Series Type : Expression profiling by high throughput sequencing ; Methylation profiling by high throughput sequencingOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
- GSE289561 Long-term chronic exposure of mice to sodium fluoride and a mixture of endocrine disruptors lead to easily observable tooth enamel and retina abnormalities underlying changes in hepatic metabolism February 14, 2026Contributors : Emilie Picard ; Fatima Domenica Elisa De Palma ; Sophia Loiodoce ; Vincent Carbonnier ; Seiki Achiedo ; Noor Mimoun ; Diluxe Mutale ; Sophie Doublier ; Sylvère Durand ; Mélanie Bourgin ; Fanny Aprohamian ; Pierre Cordier ; Louise Gutter ; Katia Jedeon ; Marie-Christine Naud ; Philippe Noirez ; Jean-Marc Ricort ; Lotfi Slimani ; Guido Kroemer ; […]
- GSE286416 Multiscale profiling of tyrosine kinase inhibitor cardiotoxicity reveals mechanosensitive ion channel PIEZO1 as cardioprotective February 14, 2026Contributors : David Wu ; Nazish SayedSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTyrosine kinase inhibitors (TKIs) have transformed cancer therapy but are associated with significant cardiovascular risks, including hypertension and heart failure. Here, we demonstrate that endothelial dysfunction driven by impaired […]
- GSE313619 Multiple Factors Contribute to Guaiacol Production by Alicyclobacillus acidoterrestris and Alicyclobacillus suci in Apple Juice, as revealed by Transcriptomic and Phenotypic Analyses February 14, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Alicyclobacillus acidoterrestris ; Alicyclobacillus suciAlicyclobacillus acidoterrestris and Alicyclobacillus suci are both guaiacol producers that can cause spoilage in products like juices. To study the genetic underpinnings of guaiacol production, transcriptomics was performed on m […]
- GSE290820 Engineering intrinsically disordered regions (IDRs) for guiding genome navigation February 14, 2026Contributors : Jing Liu ; Divya Krishna Kumar ; Bohdana Hurieva ; Felix Jonas ; Naama BarkaiSeries Type : OtherOrganism : Saccharomyces cerevisiaeProfiling denovo IDR sequences fused to different DBDs to reveal the IDR grammar underlying targeting specificity
- GSE317352 Early adjunct anti-PD-L1 therapy improves outcomes and reverses immune paralysis in murine pulmonary mucormycosis February 14, 2026Contributors : Sebastian Wurster ; Dimitrios P Kontoyiannis ; Jezreel Pantaleón GarcíaSeries Type : Expression profiling by arrayOrganism : Mus musculusInvasive pulmonary mucormycosis (IPM) is a severe opportunistic mold infection whose outcome is predominantly host driven. Preclinical proof-of-concept studies and clinical case reports in salvage therapy set […]
- GSE319060 Development and Characterization of an Inducible Tensin1 Deficient Transgenic Murine Model February 14, 2026Contributors : Ksenija Bernau ; Kelsey Holbert ; Ivy S. McDermott ; Babita Rahar ; Kade W. Coulter ; Madalyn A. Osterhaus ; Thomas J. Harr ; Carson Gehl ; Angie T. Oler ; Christopher Huffman ; Beth Gray ; Trevor S. Langel ; Kenneth M. Chan ; Amir Forati ; Sandra Splinter BonDurant ; Mark Berres ; Kathy J. Krentz ; C. Dustin Rubinstein ; Andres F. Mejia ; Nat […]
- GSE319070 SMARCA4 Promotes Lineage Plasticity and Enzalutamide Resistance in Prostate Cancer by Regulating PROX1 via H3K27 Acetylation February 14, 2026Contributors : Chenwei Wu ; Mayao Luo ; Shidong Lv ; Qiang WeiSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensEnzalutamide resistance is a dynamic process often culminating in the aggressive progression to neuroendocrine prostate cancer (NEPC). This lineage plasticity is hypothesized to be driven by underl […]
- GSE319387 Serum tsRNA-Gly-5-0006 in breast cancer: Differential expression and effects on cancer cell biology February 14, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensBreast cancer (BC) is a leading cause of female mortality worldwide, largely due to metastatic progression and the absence of reliable non-invasive biomarkers for early detection. This study investigates the potential of tRNA-derived small RNA fragments (tRFs) as novel dia […]
- GSE319496 Association between blood parameters, whole-blood transcriptomic profiles, and immune-related adverse events in metastatic renal cell carcinoma during nivolumab plus ipilimumab February 14, 2026Contributors : Satoka Kinase ; Yoshiyuki Nagumo ; Bunpei Isoda ; Hiromichi Sakurai ; Reo Takahashi ; Shuhei Suzuki ; Akane Yamaguchi ; Ryota Yanagihashi ; Kozaburo Tanuma ; Satoshi Nitta ; Masanobu Shiga ; Kosuke Kojo ; Atsushi Ikeda ; Takashi Kawahara ; Akio Hoshi ; Shuya Kandori ; Bryan J Mathis ; Hiroyuki NishiyamaSeries Type : Expression profiling by hig […]