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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE285423 Digital transformation of herbal medicine: Conversion to biological entity data using Qi related decoction and constituent herbal medicine-induced transcriptome sequencing_third_HT29_batchE May 14, 2026Contributor : Musun ParkSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThis study aimed to identify transcript expression induced by Qi-related herbal medicines (QHM) and modes of action (MOA) of QHM in HT29 cell line. For the production of QHM-induced transcripts, Qi-related herbal medicines water extract (QHW) and Qi […]
- GSE285418 Digital transformation of herbal medicine: Conversion to biological entity data using Qi related decoction and constituent herbal medicine-induced transcriptome sequencing_third_HT29_batchA May 14, 2026Contributor : Musun ParkSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThis study aimed to identify transcript expression induced by Qi-related herbal medicines (QHM) and modes of action (MOA) of QHM in HT29 cell line. For the production of QHM-induced transcripts, Qi-related herbal medicines water extract (QHW) and Qi […]
- GSE297181 Repression of Progenitor Programs Safeguards Pancreatic Endocrine Cell Identity May 14, 2026Contributors : Valéria Fabríciová ; Romana Bohuslavová ; Laura Lebrón-Mora ; Věra Slaninová ; Pavel Abaffy ; Zuzana Berková ; František Saudek ; Gabriela PavlínkováSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPancreatic endocrine cells regulate glucose homeostasis and energy metabolism in response to nutrients. All p […]
- GSE285552 Digital transformation of herbal medicine: Conversion to biological entity data using Qi related decoction and constituent herbal medicine-induced transcriptome sequencing_third_SW1783_batchD May 14, 2026Contributor : Musun ParkSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThis study aimed to identify transcript expression induced by Qi-related herbal medicines (QHM) and modes of action (MOA) of QHM in SW1783 cell line. For the production of QHM-induced transcripts, Qi-related herbal medicines water extract (QHW) and […]
- GSE330617 Transcriptomic profiling of astrocytes under three extracellular acidification conditions May 14, 2026Contributors : Xiangdong Liu ; Junyan Wang ; Jingqi Guan ; Enzhe Zhang ; Shujin Li ; Bin CongSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusExtracellular acidosis is a common feature of multiple pathological microenvironments, such as ischemia, tumors, inflammation, metabolic dysregulation, and tissue injury. Astrocyte […]
- GSE299122 Stromal Cell Senescence Augments Hematopoietic Cell Fitness in Clonal Hematopoiesis May 14, 2026Contributors : Navarro Figueredo Anna ; Mistry Jayna ; Trowbridge Jennifer ; Götze KatharinaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensNon-cell-autonomous mechanisms impact tumor growth and metastasis, including remodeling of the tissue microenvironment. The extent to which remodeling of the microenvironment promot […]
- GSE327634 PALINCODE: Recording cell lineage with ternary palindromic CRISPR bits May 14, 2026Contributors : Fathi Maryam ; Cook Aidan ; Bagheri Meisam ; Curiel Tyler ; McKenna AaronSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Homo sapiensReconstructing complete and accurate lineage trees remains a long-standing challenge in biology. Here, we introduce PALINCODE (Palindromic Coding and Decoding), a system that ut […]
- GSE281074 Digital transformation of herbal medicine: Conversion to biological entity data using Qi related decoction and constituent herbal medicine-induced transcriptome sequencing_third_HepG2_batchC May 14, 2026Contributor : Musun ParkSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThis study aimed to identify transcript expression induced by Qi-related herbal medicines (QHM) and modes of action (MOA) of QHM in HepG2 cell line. For the production of QHM-induced transcripts, Qi-related herbal medicines water extract (QHW) and Q […]
- GSE329396 RNA sequencing of A549 lung cancer cells treated with a copper(I) bisphosphine complex (Complex 1) May 14, 2026Contributors : Evelyn Priya Peter ; Zi Yu Khoo ; Huey Teng Liew ; Jing En Tan ; Ameena Tariq Rana ; Wen Xuan Lee ; En Ci Chen ; Yi-Chin Lu ; Tzu Wei Tseng ; Hui Xuan Lim ; Tze Pheng Lau ; Ally Chien Ing Yeo ; Felicia Fei-Lei ChungSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCopper-based complexes are emerging as prom […]
- GSE328815 Codon degeneracy contributes to divergent fitness effects of rare tRNAs with A34 May 14, 2026Contributors : Parth K Raval ; Sungbin Lim ; Jenna Gallie ; Deepa AgasheSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Escherichia coliTransfer RNA (tRNA) repertoires vary greatly across genomes, shaped by genetic drift and selection. A peculiar pattern across prokaryotes is the near-complete absence of tRNAs with unmodified a […]
- GSE330032 Subtype-specific heterogeneity of anti-epidermal growth factor receptor antibody sensitivity in KRAS-mutant colorectal cancer revealed by patient-derived organoids May 14, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensAnti–epidermal growth factor receptor (anti-EGFR) antibodies are widely used in the treatment of colorectal cancer (CRC), and KRAS mutation status is commonly used as a predictive biomarker for therapeutic responsiveness. Nevertheless, emerging evidence suggests that drug […]
- GSE330548 Multi-Omics Integration Identifies Critical Molecular Drivers and Alternative Splicing Events in Small Cell Lung Cancer II May 14, 2026Contributors : Ziqing Gao ; Yongkun Huo ; Qi Fu ; Kaizhao Chen ; Shuaishuai Zhang ; Mingtian Zhong ; Hua Wu ; Xiaodong Ma ; Ming LiuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSmall cell lung cancer (SCLC) remains a highly aggressive malignancy and a therapeutic challenge in clinical oncology. Here, we conducted an […]
- GSE330569 Transcriptomic data of the placenta from post-term mice caused by the absence of steroid hormone receptor coactivators May 14, 2026Contributors : Huaiyan Chen ; Lu GaoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusParturition depends on precise communication between the mother and fetus.Our previous study demonstrated that wild-type mice carrying fetuses doubly deficient in steroid receptor coactivators (Src)-1 and Src-2 (Src-1/-2d/d) manifested a […]
- GSE284438 Digital transformation of herbal medicine: Conversion to biological entity data using Qi related decoction and constituent herbal medicine-induced transcriptome sequencing_third_A549_batchD May 14, 2026Contributor : Musun ParkSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThis study aimed to identify transcript expression induced by Qi-related herbal medicines (QHM) and modes of action (MOA) of QHM in A549 cell line. For the production of QHM-induced transcripts, Qi-related herbal medicines water extract (QHW) and Qi […]
- GSE326755 The C-terminal region of TENT5 Proteins Drives ER-associated mRNA Polyadenylation via FNDC3 interaction [TAIL-Seq] May 14, 2026Contributors : Lisa Viviani ; Daniel Lacidogna ; Sara Pennacchio ; Maria Vittoria Mengozzi ; Ugo Orfanelli ; Leone Giordano ; Tommaso Perini ; Simone Cenci ; Enrico MilanSeries Type : OtherOrganism : Homo sapiensSpatial regulation of mRNA polyadenylation is a key emerging mechanism shaping cellular function. The TENT5/FAM46 family comprises four non-canonica […]