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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE317049 Sodium Alginate Activates Subcutaneous Fat Differentiation via the PPAR Pathway February 5, 2026Contributors : Yufan Gan ; Kai LiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo investigate the effect of sodium alginate on adipocyte differentiation, we isolated the stromal vascular fraction (SVF) from wild-type C57BL/6J mice and subjected it to whitening treatment. During the induction of differentiation, sodium […]
- GSE316931 Transcriptome analysis of Arabidopsis sqtl1 mutant February 5, 2026Contributors : Zhi-Xing Lau ; Ya-Huei Chen ; Donghui Wei ; Gu Ying ; Kai-Yin Lo ; Wan-Hsing ChengSeries Type : Expression profiling by high throughput sequencingOrganism : Arabidopsis thalianaDifferential gene expression of Arabidopsis ribosome biogenesis related gene SQTL1, by comparing transcriptome of sqtl1 RNAi mutant with WT Col-0.
- GSE318441 Coordination of nuclear RNA processing by speckle-localized kinase TAOK2 February 5, 2026Contributors : Bridget Begg ; Shengyan Gao ; Kristen Lynch ; Beatriz FountouraSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensNuclear speckles are membraneless organelles that act as active splicing hubs especially at sites of high transcription. Emerging views of this dynamic subnuclear structure place it as a hub of R […]
- GSE317226 HIF regulatory network reflects kidney disease progression in diabetes and reversal with SGLT2 inhibition February 5, 2026Contributors : Viji Nair ; Cathy Smith ; Celine C Berthier ; Matthias Kretzler ; Jennifer A SchaubSeries Type : OtherOrganism : Homo sapiensHypoxia drives diabetic kidney disease (DKD) progression through Hypoxia Inducible Factor (HIF) signaling. The kidney’s cellular heterogeneity and complex architecture pose challenges for directly assessing the pharmacol […]
- GSE288890 Positional guidance for Schwann cells to build nerve bridge after injury requires Plexin-B1-mediated collision repulsion February 5, 2026Contributors : Jiaxi Li ; Haofei Ni ; Dalia Halawani ; Molly Estill ; Aarthi Ramakrishnan ; Chrystian J Alves ; Li Shen ; Xijing He ; Roland H Friedel ; Hongyan ZouSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPositional cues are critical to guide orientation of cell movement and morphological transformation during ti […]
- GSE288782 LACTB inhibits lipid synthesis to suppress glioma growth by promoting Hsc70-mediated ERBB3 degradation February 5, 2026Contributors : Yanjia Hu ; Zhaoying Zhu ; Yeng Ye ; Xin Qi ; Yang Wei ; Denian Wang ; Meng TianSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensAbnormal lipid metabolism is a hallmark of tumor and represents an anti-cancer strategy. β-lactamase like protein (LACTB) is a novel tumor suppressor, but the biological function […]
- GSE318279 Self-clustering of three CBX2 molecules drives PRC2 to promote facultative heterochromatinization of Polycomb target genes February 5, 2026Series Type : Genome binding/occupancy profiling by high throughput sequencing ; Other ; Expression profiling by high throughput sequencingOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE310929 Deciphering sepsis molecular subtypes using large-scale data to identify subtype-specific drug repurposing February 5, 2026Contributors : Leslie A Smith ; Kiley Graim ; Faheem Guirgis ; Beulah Augustin ; Vinitha Jacob ; Lauren P Black ; Andrew Bertrand ; Emilio Cagmat ; Susmita Datta ; Srinivasa T Reddy ; Charlotte HopsonSeries Type : Expression profiling by high throughput sequencing ; Third-party reanalysisOrganism : Homo sapiensRationale: Sepsis is a life-threatening syndrome […]
- GSE318284 Acsl1 mediated FA Synthesis Impairs Osseointegration in type I diabetes [ATAC-Seq] February 5, 2026Contributors : Xinghui Zheng ; Xingyu Zhu ; Xu Chen ; Qingqing He ; Qingming Zhai ; Tao ChenSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusDiabetes mellitus is considered a relative contraindication for oral implant therapy, as hyperglycemia frequently precipitates vascular and osseous pathologies. Althou […]
- GSE318283 Acsl1 mediated FA Synthesis Impairs Osseointegration in type I diabetes February 5, 2026Contributors : Xinghui Zheng ; Xingyu Zhu ; Xu Chen ; Qingqing He ; Qingming Zhai ; Tao ChenSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusDiabetes mellitus is considered a relative contraindication for oral implant therapy, as hyperglycemia frequently precipitates vascular and osseous pathologies. Although clinicians […]
- GSE318286 SAGA/ATAC complexes sustain aberrant chromatin regulation and promote tumorigenesis in diffuse midline glioma [CUT&Run] February 5, 2026Contributors : Richard Rosemary ; Akdes Serin-Harmanci ; Jamie N AnastasSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensDiffuse midline gliomas (DMG) are aggressive pediatric brain tumors characterized by chromatin and transcriptional dysregulation induced by H3K27M mutations. Strategies for overcoming epi […]
- GSE318346 Small molecule-directed differentiation of submerged-cultured human nasal airway epithelia for respiratory disease modelling [bulkRNA-seq] February 5, 2026Contributors : Hetty M Dreyer ; Jeffrey M Beekman ; Gimano D AmatngalimSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensSubmerged cultures of undifferentiated or transformed epithelial cells are widely used in respiratory research due to their ease of use and scalability. However, these systems fail to capture the cellul […]
- GSE318347 Small molecule-directed differentiation of submerged-cultured human nasal airway epithelia for respiratory disease modelling [scRNA-seq] February 5, 2026Contributors : Hetty M Dreyer ; Jeffrey M Beekman ; Gimano D AmatngalimSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensSubmerged cultures of undifferentiated or transformed epithelial cells are widely used in respiratory research due to their ease of use and scalability. However, these systems fail to capture the cellul […]
- GSE311093 Zeb2os Hinders Cardiac Healing by Suppressing ZEB2 Reactivation and Cardiomyocyte Dedifferentiation [2] February 5, 2026Contributors : Monika M Gladka ; Rocco Caliandro ; Merel L Ligtermoet ; Alexandra E Giovou ; Azra HuseticSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBackground: Long noncoding RNAs (lncRNAs) have emerged as critical regulators in cardiovascular biology, influencing cardiac development, remodeling, and regeneration. […]
- GSE318278 Self-clustering of three CBX2 molecules drives PRC2 to promote facultative heterochromatinization of Polycomb target genes [RNA-Seq] February 5, 2026Contributors : Steven Ingersoll ; Abby Trouth ; J. Carlos Angel ; Xinlong Luo ; Axel Espinoza ; Joey Wen ; Chengjie Zhu ; Joseph Tucker ; Kalkidan Astatike ; Christopher J Phiel ; Hatim Sabaawy ; Tatiana G Kutateladze ; Tao P. Wu ; Tingting Yao ; Chao Lu ; Srinivas Ramachandran ; Xiaojun RenSeries Type : Expression profiling by high throughput sequencingOrga […]