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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE309281 Surface mechanics and compressive stress impact mammalian follicle development October 15, 2025Contributors : Chii Jou Chan ; Arikta Biswas ; Kosei TomidaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe maturation of functional eggs in ovaries is essential for successful reproduction in mammals. Despite its biological and clinical importance, the underlying mechanisms regulating folliculogenesis remain enigmat […]
- GSE244086 MMPs and NETs are detrimental in CNS-tuberculosis with MMP inhibitor doxycycline improving murine CNS-tuberculosis survival (mouse) October 15, 2025Contributors : Catherine M Ong ; Joshua X Tay ; Andres F Vallejo ; Fei K Loh ; Wei K TeoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusDespite effective anti-tuberculous treatment (ATT), up to 40% of patients with central nervous system tuberculosis (CNS-TB) suffer permanent neurological deficits and death. Immunopatho […]
- GSE220566 Deletion of the X chromosome gene Kdm6a in microglia is protective in the multiple sclerosis model October 15, 2025Contributors : Yuichiro Itoh ; Rhonda VoskuhlSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMultiple sclerosis (MS) exhibits a sex difference in susceptibility with females affected more frequently than males. Sexual dimorphisms may be due to differences in sex hormones, sex chromosomes, or both. Regarding sex chromoso […]
- GSE268416 An intracellular magnetic torque-regulator drives mechano-sequential antitumor immunity [RNA-seq] October 15, 2025Contributors : Rui Gao ; Chang Xu ; Zhenyan Zhu ; Chen Liu ; Min Wang ; Xueyan Wei ; Peng Ning ; Wei Zhang ; Yingze Li ; Junwu Shen ; Yajuan Zhang ; Yifan Tong ; Feng Tao ; Xiaolei Chen ; Xiaoyi Jiang ; Huan Ren ; Cheng Lv ; Gustavo R Plaza ; Jason Miska ; Haiming Fan ; Yichao Tang ; Yalei Dai ; Weiwei Yang ; Bin He ; Yu ChengSeries Type : Expression profili […]
- GSE261726 Deletion of the X chromosome gene Kdm6a in microglia is protective in the multiple sclerosis model, female and male II October 15, 2025Contributors : Yuichiro Itoh ; Rhonda VoskuhlSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMultiple sclerosis (MS) exhibits a sex difference in susceptibility with females affected more frequently than males. Sexual dimorphisms may be due to differences in sex hormones, sex chromosomes, or both. Regarding sex chromoso […]
- GSE279533 CD48 affects type-2 innate lymphoid cell function and airway hyperreactivity. October 15, 2025Contributor : Kei SakanoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe importance of type-2 innate lymphoid cell (ILC2), as well as its function in allergic airway inflammatory diseases, have attracted growing attention over recent years. It is anticipated that further elucidation of ILC2 function and regulatory me […]
- GSE276125 An intracellular magnetic torque-regulator drives mechano-sequential antitumor immunity October 15, 2025Contributors : Rui Gao ; Chang Xu ; Zhenyan Zhu ; Chen Liu ; Min Wang ; Xueyan Wei ; Peng Ning ; Wei Zhang ; Yingze Li ; Junwu Shen ; Yajuan Zhang ; Yifan Tong ; Feng Tao ; Xiaolei Chen ; Xiaoyi Jiang ; Huan Ren ; Cheng Lv ; Gustavo R Plaza ; Jason Miska ; Haiming Fan ; Yichao Tang ; Yalei Dai ; Weiwei Yang ; Bin He ; Yu ChengSeries Type : Expression profili […]
- GSE307750 PCBP1 binding to single-stranded poly-cytosine motifs enhances cGAS sensing and impairs breast cancer development [snRNA-Seq] October 15, 2025Contributors : Cécile Fréreux ; Joseph A Karam ; Breege V Howley ; Bryan Granger ; Paramita Chakraborty ; Annamarie C Dalton ; Bidyut K Mohanty ; Silvia Vaena ; Romeo Martin ; Shikhar Mehrotra ; Philip H HoweSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe cGAS-STING pathway plays a central role in controlling tumor […]
- GSE307616 PCBP1 binding to single-stranded poly-cytosine motifs enhances cGAS sensing and impairs breast cancer development October 15, 2025Contributors : Cécile Fréreux ; Joseph A Karam ; Breege V Howley ; Bryan Granger ; Paramita Chakraborty ; Annamarie C Dalton ; Bidyut K Mohanty ; Silvia Vaena ; Romeo Martin ; Shikhar Mehrotra ; Philip H HoweSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe cGAS-STING pathway plays a central role in controlling tumor […]
- GSE308467 Sexually Dimorphic Sail Feathers in the Mandarin Duck: A Model for Lifelong Developmental Modulation [ChIP-seq] October 15, 2025Contributors : Pin-Chi Tang ; Hsu-Chen Cheng ; Gee-Way Lin ; Yung-Chih Lai ; Ya-Chen Liang ; Ping Wu ; Tzu-Chiao Lin ; Chen Siang Ng ; Isheng Tsai ; Ang Li ; Wen Hsiung Li ; Chih-Feng Chen ; Cheng-Ming Chuong ; Randall WidelitzSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Aix galericulataDevelopmental processes exte […]
- GSE308466 Sexually Dimorphic Sail Feathers in the Mandarin Duck: A Model for Lifelong Developmental Modulation [RNA-seq] October 15, 2025Contributors : Pin-Chi Tang ; Hsu-Chen Cheng ; Gee-Way Lin ; Yung-Chih Lai ; Ya-Chen Liang ; Ping Wu ; Tzu-Chiao Lin ; Chen Siang Ng ; Isheng Tsai ; Ang Li ; Wen Hsiung Li ; Chih-Feng Chen ; Cheng-Ming Chuong ; Randall WidelitzSeries Type : Expression profiling by high throughput sequencingOrganism : Aix galericulataDevelopmental processes extend beyond embr […]
- GSE308492 CD2 costimulation strength: A key regulator of T cell function and anti-tumour immunity that is epigenetically regulated. October 15, 2025Contributors : Philippos Demetriou ; Maria Iakovou ; Gregoria Gregoriou ; Dimitris Vrachnos ; Jianxiang Chi ; Athos Antoniades ; Paul CosteasSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCD2 is a key costimulatory receptor on human T cells, but its surface abundance regulation and the functional significance of it rem […]
- GSE308705 Non-Invasive Detection of Bone Marrow Fibrosis in Myeloproliferative Neoplasms Using Cell-Free RNA October 15, 2025Contributors : Mohamed Saad ; Stijn Fuchs ; Carmen Schalla ; Katrin Götz ; Jessica E Pritchard ; Niclas Flosdorf ; Adam Benabid ; Hélène Gleitz ; Nils Leimkühler ; Aurélien Dugourd ; Rebekka K SchneiderSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensMyeloproliferative neoplasms (MPNs), particularly with myelofibrosis ( […]
- GSE308812 Single-cell gene expression analysis of ulcerated skin in Has2 transgenic and wild-type mice with scratching-induced ulcerative derm October 15, 2025Contributors : Jieyi Meng ; Fan Wu ; Hong Zhou ; Malay Shah ; Yi ZhuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusUlcerative dermatitis (UD) in mice is an idiopathic skin disease characterized by intense pruritus, hair loss, self-inflicted lesions, and progression to ulceration. UD serves as a model for chronic skin i […]
- GSE280367 Mesenchymal Colorectal Cancers Secrete Vesicles With Unique Cargo That Can Be Used For Liquid Biopsy Based Diagnostics [RNA-seq] October 15, 2025Contributors : Paris J Asif ; Lauri H Borghuis ; Sander R van Hooff ; Anita E Grootemaat ; Monique A van Eijndhoven ; Johan de Rooij ; Nils J Groenewegen ; Nicole N van der Wel ; Arezo Torang ; Tineke E Buffart ; Michiel D Pegtel ; Jan Paul MedemaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTumor-derived extracellula […]