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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE201980 Brain-cervical lymph node crosstalk contributes to brain injury-induced by subarachnoid hemorrhage in mice August 14, 2025Contributors : Jiman Chen ; Jie WangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo explore the mechanism of how red blood cells activate lymphatic endothelial cells thereby macrophage pro-inflammatory polarizationwe performed RNA-seq analysis of lymphatic endothelial cells after they were treated by red blood cells […]
- GSE275009 Population and functional diversity of aged lymph node stromal cells during viral infection August 14, 2025Contributors : Allison K Bennett ; Maria P Zappia ; Mark Sanborn ; Michelle Richner ; Jalees Richner ; Maxim V Frolov ; Justin M RichnerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusAging correlates with delayed and blunted adaptive immune responses following infection and vaccination leading to increased susceptibili […]
- GSE261821 The G-Protein-Coupled Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis August 14, 2025Contributors : Alejandro Asensio ; Ramon Garcia-Escudero ; Federico Mayor Jr ; Catalina RibasSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTightly regulated cell-cell and cell-niche intercommunications via intertwined signaling networks are involved in maintaining normal hair follicle (HF) homeostasis, cycling and cel […]
- GSE283664 RNA Sequencing of macrophages harboring redox-diverse Mycobacterium tuberculosis. August 14, 2025Contributors : Vikas Yadav ; Sarthak Sahoo ; Nitish Malhotra ; Mohit Jolly ; Aswin Sai Narain Seshasayee ; Amit SinghSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe ability of Mycobacterium tuberculosis (Mtb) to tolerate antibiotics is a major impediment in the treatment of tuberculosis. This antibiotic tolerance is […]
- GSE275573 Role of ADAR1 on transcriptional output in cancer cells August 14, 2025Contributors : Xuliren Wang ; Zhibo Shao ; Qi Zhang ; Jiong WuSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Homo sapiensThe loss of ADAR1 significantly reduced ribosome production, decreased tumor translational efficiency, and impaired the translation of oncogenic pathways.
- GSE295384 ATF3 Overexpression Induces Cardiac Hypertrophy and Electrical Dysfunction through Enhanced Proliferation in Zebrafish August 14, 2025Contributor : Jung-Woong KimSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioActivating transcription factor 3 (ATF3) is a key regulator of gene expression in response to physiological stress across various tissues. Although its abnormal expression has been linked to cardiac dysfunction, the precise mechanisms by which AT […]
- GSE283874 RNA Sequencing of Mycobacterium tuberculosis-infected macrophages treated with meclizine. August 14, 2025Contributors : Vikas Yadav ; Sarthak Sahoo ; Nitish Malhotra ; Mohit Jolly ; Aswin Sai Narain Seshasayee ; Amit SinghSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe ability of Mycobacterium tuberculosis (Mtb) to tolerate antibiotics is a major impediment in the treatment of tuberculosis. This antibiotic tolerance is […]
- GSE295771 Brain-cervical lymph node crosstalk contributes to brain injury-induced by subarachnoid hemorrhage in mice August 14, 2025Contributors : Jinman Chen ; Jie Wang ; Wenjing Zheng ; Lianping Xing ; Yongjun Wang ; Qianqian LiangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe neuroinflammation and peripheral immune response following subarachnoid hemorrhage (SAH) aggravates early brain injury and lead to poor prognosis. Cross-talk between br […]
- GSE304956 Non-severe burn injury leads to sustained molecular changes in the brain in a murine model August 14, 2025Contributors : Amira Allahham ; Nutan Chaudhari ; Sarah Walsh ; Blair Z Johnson ; Andrew Stevenson ; Samantha Lodge ; Drew Hall ; Zhenjun Deng ; Rongchang Yang ; Monique Ryan ; Phillip E Melton ; Jennifer Rodger ; Fiona M Wood ; Luke Whiley ; Mark FearSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBackground: Paediatri […]
- GSE305185 Identification of a new subpopulation of myonuclei during skeletal muscle hypertrophy August 14, 2025Contributors : Léa Delivry ; Pascal Maire ; Athanassia SotiropoulosSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe have employed a single nucleus sequencing approach using 10x Genomics snRNA-seq to study the process of skeletal muscle hypertrophy. We examined the plantaris muscle of control adult mice (Ctl) and adult […]
- GSE305359 RNA-Sequencing of HEK293 During Adeno-Associated Virus Production [EXPA] August 14, 2025Contributor : Niklas KraemerSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensRecombinant viral vectors such as adeno-associated viruses (AAV) have emerged as a key tool in gene therapy applications. Despite extensive research efforts aimed at increasing production yields, the intricate molecular mechanisms that govern th […]
- GSE305360 RNA-Sequencing of HEK293 During Adeno-Associated Virus Production [EXPB] August 14, 2025Contributor : Niklas KraemerSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensRecombinant viral vectors such as adeno-associated viruses (AAV) have emerged as a key tool in gene therapy applications. Despite extensive research efforts aimed at increasing production yields, the intricate molecular mechanisms that govern th […]