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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE240245 The feather moss Hylocomium splendens affects the transcriptional profile of a symbiotic cyanobacterium in relation to acquisition and turnover of key nutrients August 7, 2025Contributors : Danillo Oliveira Alvarenga ; Anders Priemé ; Kathrin RouskSeries Type : Expression profiling by high throughput sequencingOrganism : Hylocomium splendens ; Nostocaceae cyanobacteriumWe isolated a cyanobacterium from H. splendens and co-incubated it with H. splendens shoots. Cyanobacterium and moss were also incubated separately. After one week […]
- GSE304704 The effects of Cryopreservation on PBMCs transcriptome profile August 7, 2025Contributors : Xuan Li ; Qian Chen ; Jeanette Higgins ; Kendal Cook ; Michael W Baseler ; Tomozumi Imamichi ; Weizhong ChangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCryopreservation is a key method for long-term storage of biological specimens. The development of optimal cryopreservation condition will reduce the […]
- GSE272534 Chromatin-dependent motif syntax defines differentiation trajectories [RNA-seq] August 7, 2025Contributors : Sevi Durdu ; Murat Iskar ; Luke Isbel ; Leslie Hoerner ; Christiane Wirbelauer ; Lukas Burger ; Daniel Hess ; Vytautas Iesmantavicius ; Dirk SchübelerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTranscription factors that recognize short DNA sequence motifs within gene regulatory elements are key drive […]
- GSE272524 Chromatin-dependent motif syntax defines differentiation trajectories [ChIP-seq] August 7, 2025Contributors : Sevi Durdu ; Murat Iskar ; Luke Isbel ; Leslie Hoerner ; Christiane Wirbelauer ; Lukas Burger ; Daniel Hess ; Vytautas Iesmantavicius ; Dirk SchübelerSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusTranscription factors that recognize short DNA sequence motifs within gene regulatory elements […]
- GSE274245 Adhesion-Related Macrophages Regulates Metabolic Homeostasis through CAV-1 Dependency August 7, 2025Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe significance of adipose tissue macrophages (ATMs) in regulating adipose tissue function is well-established. However, our investigation revealed a previously overlooked subpopulation of macrophages adhered to adipocytes, which we term adhesion-related macrophages (ARMs […]
- GSE272555 Chromatin-dependent motif syntax defines differentiation trajectories August 7, 2025Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencing ; OtherOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE294220 Acquisition of neural crest promoted thyroid evolution from chordate endostyle August 7, 2025Contributors : Jan Stundl ; Ayyappa Raja Desingu Rajan ; Marianne E BronnerSeries Type : Expression profiling by high throughput sequencingOrganism : Petromyzon marinusThe endostyle is an endodermal organ unique to non-vertebrate chordates except for lamprey larvae, where it serves as forerunner to the adult thyroid. Here, we examine if the acquisition of ne […]
- GSE274948 Transcriptomic Landscape of Fibroblasts Under IL-1β Stimulation [ATAC-seq] August 7, 2025Contributors : Ming Zhao ; Xiaoyun Chen ; Yueqi QiuSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensIn this study, we investigated the chromatin accessibility changes in human dermal fibroblasts in response to IL-1尾 stimulation, a key pro-inflammatory cytokine. Using ATAC-seq, we compared the open chromatin […]
- GSE300787 TUMOR-INFILTRATING NOCICEPTOR NEURONS PROMOTE IMMUNOSUPPRESSION [MDSC] August 7, 2025Contributors : Sebastien Talbot ; Mohammad Balood ; Amin R NikpoorSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusNociceptor neurons impact tumor immunity. Removing nociceptor neurons reduced myeloid-derived suppressor cell (MDSCs) tumor infiltration in mouse models of head and neck carcinoma and melanoma. Carcinoma-rel […]
- GSE300254 TUMOR-INFILTRATING NOCICEPTOR NEURONS PROMOTE IMMUNOSUPPRESSION August 7, 2025Contributors : Sebastien Talbot ; Maryam Ahmadi ; Amin R NikpoorSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusNociceptor neurons impact tumor immunity. Removing nociceptor neurons reduced myeloid-derived suppressor cell (MDSCs) tumor infiltration in mouse models of head and neck carcinoma and melanoma. Carcinoma-relea […]
- GSE301763 T cell-intrinsic cGAS-CTCF regulation maintains regulatory T cell development and function August 7, 2025Series Type : Genome binding/occupancy profiling by high throughput sequencing ; Other ; Expression profiling by high throughput sequencingOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE304146 Retinoic acid receptor-related orphan receptor α regulates bystander activation of memory CD8+ T cells [RNA-Seq] August 7, 2025Contributors : Zimeng Cai ; Mina Kozai ; Hironobu Mita ; Hiroto Takeuchi ; Satoru Mizuno ; Kazuhiro matsuo ; Kensuke TakadaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBackground: Memory CD8+ T cells sense inflammation and rapidly produce interferon-γ (IFN-γ) independent of cognate antigens. This innate-like property […]
- GSE304242 In vitro and in vivo models to predict ADAR RNA editing oligonucleotides potential in human liver tissue August 7, 2025Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensLiver-originated diseases remain a significant global health burden, with limited treatment options available. RNA therapeutics, particularly adenosine deaminase acting on RNA (ADAR)-mediated editing using editing oligonucleotides (EONs) offer a novel approach to address t […]
- GSE289155 Time-course small RNA sequencing across photoperiods in Arabidopsis thaliana August 7, 2025Contributors : Chun Chung Leung ; Daniel A Tarté ; Joshua M GendronSeries Type : Expression profiling by high throughput sequencingOrganism : Arabidopsis thalianaSmall RNAs play important roles in photoperiodism, but a comprehensive characterization of miRNAs and the more recently recognized tRFs within this context is lacking. Herein, we characterize the pa […]
- GSE293906 Intestinal mast cell-derived leukotrienes mediate the anaphylactic response to ingested antigens August 7, 2025Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.