Quick Links : Search PubMed , Finding Full Text , PubMed Advanced Search , Clinical Queries , Single Citation Matcher , FAQs & User Guide , Explore MeSH Database , Explore PubMed Journals
Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE214682 The histone H3 lysine 36 demethylase KDM2A/FBXL11 is essential for germ cell development in male mice June 13, 2025Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencing ; Methylation profiling by high throughput sequencingOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE299326 Time-course transcriptome analysis of podocyte injury in Pod-TRECK mice June 13, 2025Contributors : Masaki Watanabe ; Kenta Nakano ; Tadashi Okamura ; Nobuya SasakiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPodocytes are critical components of the glomerular filtration barrier, and their injury leads to chronic kidney disease (CKD). To elucidate the temporal molecular responses following podocyte d […]
- GSE266889 SMART-seq2 of activated human plasmacytoid dendritic cells June 13, 2025Contributors : Rebeca Arroyo Hornero ; Juliana IdoyagaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensPlasmacytoid and conventional dendritic cells (pDCs and cDCs, respectively) are closely related immune lineages with distinct functions. Whether pDCs can switch fate into the cDC lineage has remained controversial. Here […]
- GSE249326 Non-canonical AMPA receptor blockade reduces lymph node egress and neuroinflammation [Bulk RNA-seq] June 13, 2025Contributors : Beatrice Wasser ; Manuela Ecker ; Nicholas Hanuscheck ; Erik Ellward ; Muthuraman Muthuraman ; Mohammadsaleh Oshaghi ; Stefan Bittner ; Frauke ZippSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusDisturbances in the glutamatergic system have been linked to neuronal pathology. Investigating therapeutic tran […]
- GSE271720 PUS10 driven tRNA fragmentation mediates transposon induced inflamation [HSC RNA-seq] June 13, 2025Contributors : Magdalena Madej ; Phuong C Ngoc ; Cristian BellodiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPseudouridine (Y) is the most widespread RNA modification type on cellular RNAs and is dynamically catalyzed by a family of Y synthases (PUSes) in response to pathophysiological cues. PUS10 has been previousl […]
- GSE267433 Inactivation of histone chaperone HIRA unmasks a link between normal embryonic development of melanoblasts and maintenance of adult melanocyte stem cells June 13, 2025Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE293963 Vitamin D and Lipopolysaccharide jointly induce a distinct epigenetic and transcriptional program in Human Monocytes [ATAC-seq] June 13, 2025Contributors : Mariusz Jankowski ; Carsten CarlbergSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensPathogen-associated molecular patterns such as lipopolysaccharide (LPS) mimic immune responses triggered by bacterial infections. The hormonally active form of vitamin D, 1α,25-dihydroxyvitamin D₃ [1,25(OH)₂D […]
- GSE275116 CRAMP1-dependent histone H1 biogenesis is essential for topoisomerase II inhibitor tolerance [CUT&RUN] June 13, 2025Contributors : Louise Morlot ; Andreas Ingham ; Ignacio Alonso de Vega ; Niels MailandSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensTopoisomerase II (TOP2) inhibitors (TOP2i) are mainstay chemotherapeutic agents that undermine genome integrity by stabilizing TOP2-DNA complexes accompanied by DNA damage f […]
- GSE296917 Hydrolysis of 2-Arachidonoglycerol by Pig Liver Esterase Enhances Inflammation Induced by Porcine Reproductive and Respiratory Syndrome Virus Infection June 13, 2025Contributors : Yuelin Fu ; Huiwen Zhu ; Qiling Xiao ; Qi Chen ; Qiongqiong Zhou ; Xiliang Wang ; Deshi ShiSeries Type : Expression profiling by high throughput sequencingOrganism : Sus scrofaPorcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection induces a robust inflammation in pigs, characterized primarily by severe interstitial pneumonia. It […]
- GSE293966 Vitamin D and Lipopolysaccharide jointly induce a distinct epigenetic and transcriptional program in Human Monocytes [RNA-Seq] June 13, 2025Contributors : Mariusz Jankowski ; Carsten CarlbergSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensPathogen-associated molecular patterns such as lipopolysaccharide (LPS) mimic immune responses triggered by bacterial infections. The hormonally active form of vitamin D, 1α,25-dihydroxyvitamin D₃ [1,25(OH)₂D₃], supports i […]
- GSE297306 Transmission of Maternal Oral Pathobionts to the Infant Gut Predisposes Offspring to Exacerbated Enteritis. June 13, 2025Contributors : Masafumi Haraguchi ; Yeji Kim ; Natsuru Watanabe ; Kyoko Yamazaki ; Kira L Newman ; Merritt G Gillilland III ; Yijie Guo ; Daisuke Watanabe ; Ingrid L Bergin ; Takehiro Suzuki ; Daisuke Motooka ; Kohei Sugihara ; Sho Kitamoto ; Hiroko Nagao-Kitamoto ; Nobuhiko KamamdaSeries Type : Expression profiling by high throughput sequencingOrganism : Mu […]
- GSE297528 Effects of transient thermal stress on thyroid cancer cells June 13, 2025Contributor : Shih-Ping ChengSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensRadiofrequency ablation has been used to treat low-risk thyroid cancer; however, its oncological safety remains unclear. We applied transient sublethal thermal stress to thyroid cancer cells to simulate clinical scenarios in which incomplete ra […]
- GSE298384 ChIP and ATAC-seq data related to Rapid transcriptional response to a dynamic morphogen by time integration June 13, 2025Contributors : Susanna E Brantley ; Anna Chao ; Stefano Di Talia ; Shelby A BlytheSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Drosophila melanogasterThis study on blastoderm stage Drosophila embryos seeks to measure accessible chromatin and the enrichment on chromatin of transcription factors associated with BMP s […]
- GSE276852 CRAMP1 CUT&RUN in K562 cells June 13, 2025Contributors : Rachael E Matthews ; Iva A TchasovnikarovaSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensThe essential role of the core histones (H2A, H2B, H3 and H4) in DNA packaging has been well understood for decades, but the function of the linker histone (H1) remains enigmatic. H1 compacts nucleosome […]
- GSE293388 Drosophila melanogaster as a model organism to investigate sex specific differences June 13, 2025Contributors : Sonja Dähn ; Anika E WagnerSeries Type : Expression profiling by high throughput sequencingOrganism : Drosophila melanogasterSex differences in physiology, anatomy, behavior, and genetics are well-documented throughout the animal kingdom. These differences are often neglegted in reasearch. This imbalance can have detrimental effects, as seen i […]