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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE217603 NKT cells contribute to alleviating lung metastases in adenoid cystic carcinoma October 29, 2025Contributors : Ge-xuan Feng ; Meng-jiao ZhouSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThrough CD4 and CD8 immunohistochemical analysis, we systematically established immune desert, exclusion, and inflammatory types in SACC primary lesions and lung metastases. Notably, the majority of lung metastases exhibited immu […]
- GSE186837 A 3D in vitro mouse ovarian follicle culture system preserves molecular signatures of ovulation for studying ovulation biology and novel non-hormonal discovery October 29, 2025Contributors : Jiyang Zhang ; Brittany A Goods ; Pawat Pattarawat ; Yingzheng Wang ; Tessa Haining ; Qiang Zhang ; Alex K Shalek ; Francesca E Ducan ; Teresa K Woodruff ; Shuo XiaoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe previously established an alginate hydrogel-based 3D encapsulated in vitro follicle growth […]
- GSE279352 Adar1 as a placental innate immune rheostat to prevent endogenous dsRNA-induced integrated stress response-dependent embryonic lethality [RIP-seq] October 29, 2025Series Type : OtherOrganism : Mus musculusThe mechanisms that balance a robust antiviral defense with tissue tolerance at the maternal-fetal interface under physiological conditions remain largely unknown.
- GSE279053 Adar1 as a placental innate immune rheostat to prevent endogenous dsRNA-induced integrated stress response-dependent embryonic lethality October 29, 2025Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe mechanisms that balance a robust antiviral defense with tissue tolerance at the maternal-fetal interface under physiological conditions remain largely unknown.
- GSE279582 Adar1 as a placental innate immune rheostat to prevent endogenous dsRNA-induced integrated stress response-dependent embryonic lethality [Adar1 PKO RNA-seq] October 29, 2025Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe mechanisms that balance a robust antiviral defense with tissue tolerance at the maternal-fetal interface under physiological conditions remain largely unknown.
- GSE279579 Adar1 as a placental innate immune rheostat to prevent endogenous dsRNA-induced integrated stress response-dependent embryonic lethality [bulk RNA-seq] October 29, 2025Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe mechanisms that balance a robust antiviral defense with tissue tolerance at the maternal-fetal interface under physiological conditions remain largely unknown.
- GSE280216 Difference analysis of microRNAs in abdominal aorta of ApoE-/- AngII-induced abdominal aortic aneurysm mices October 29, 2025Contributors : Qingbin Hou ; Xiaozeng Wang ; Chenghui Yan ; Yaling HanSeries Type : Non-coding RNA profiling by arrayOrganism : Mus musculusAbdominal aortic aneurysm (AAA) is a vascular disease with high incidence at present.There is no effective drug treatment. MicroRNAs(miRNAs) play a regulatory role in the occurrence and development of AAA,and miRNA thera […]
- GSE280607 Stress controls heterochromatin inheritance through histone H3 ubiquitylation [RNA-Seq] October 29, 2025Contributors : Bharat Bhatt ; Yi Wei ; Ashis Pradhan ; Jothy Dhakshnamoorthy ; Martin Zofall ; Hua Xiao ; Drisya Vijayakumari ; Shweta Jain ; Hernan D Folco ; Hongyun Qi ; David A Ball ; Tatiana S Karpova ; David Wheeler ; Jiemin Wong ; Shiv I GrewalSeries Type : Expression profiling by high throughput sequencingOrganism : Schizosaccharomyces pombeHeterochro […]
- GSE280646 Stress controls heterochromatin inheritance through histone H3 ubiquitylation [ChIP-Seq] October 29, 2025Contributors : Bharat Bhatt ; Yi Wei ; Ashis Pradhan ; Jothy Dhakshnamoorthy ; Martin Zofall ; Hua Xiao ; Drisya Vijayakumari ; Shweta Jain ; Hernan D Folco ; Hongyun Qi ; David A Ball ; Tatiana S Karpova ; David Wheeler ; Jiemin Wong ; Shiv I GrewalSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Schizosaccharomyces p […]
- GSE280689 Modeling SMAD2 mutations in iPSCs provides insights into cardiovascular disease pathogenesis [RNA-seq] October 29, 2025Contributors : Tarsha Ward ; Warren Tai ; Sarah Morton ; Joshua Gorham ; Christine Seidman ; J.G. SeidmanSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensRationale: SMAD2 is a co-regulator that binds a variety of transcription factors and modulates activities during human development. Heterozygous SMAD2 loss-of-function […]
- GSE309119 Leukocyte-intrinsic ER stress responses contribute to chemotherapy-induced peripheral neuropathy. October 29, 2025Contributors : Miriam M Fonseca ; Oriana Gelblung ; Sarah D Pennypacker ; Taylor Brooks ; Michael Limia ; James W Morgan ; Xuewei Zhu ; Luis C Tovias-Sanchez ; Alejandro Pluma-Pluma ; Ruth Elena Martinez ; Mathew Eber ; Sun Park ; Cristina M Furdui ; Deepika Awasthi ; Alexander Emmanuelli ; Byuri A Cho ; Chen Tan ; David I Shalowitz ; Samuel S Lentz ; Michae […]