Quick Links : Search PubMed , Finding Full Text , PubMed Advanced Search , Clinical Queries , Single Citation Matcher , FAQs & User Guide , Explore MeSH Database , Explore PubMed Journals
Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE174192 Paired Metabolomic and Transcriptomic Time Series of Streptomyces coelicolor M145 Secondary Metabolism May 9, 2025Contributors : Andrew P Marshall ; Andrew R Johnson ; Erin E CarlsonSeries Type : Expression profiling by high throughput sequencingOrganism : Streptomyces coelicolorWe utilized weighted correlation networking analysis to integrate metabolite and transcription data. We demonstrate the effectiveness of this strategy and identify potential regulatory effects o […]
- GSE296209 Effects of hyperbaric oxygen on tissue-specific aging and senescence in mice and human stromal cells May 9, 2025Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiens ; Mus musculusThis study investigates the effects of hyperbaric oxygen (HBO) on cellular senescence and aging-related phenotypes. In naturally aged mice, HBO treatment reduced systemic senescence burden and reversed aging-related transcriptomic signatures in skin, liver, […]
- GSE248112 m6A is decoded by modified tRNAs to coordinate mRNA decay [miCLIP] May 9, 2025Contributors : Bastian Linder ; Puneet Sharma ; Jie Wu ; Shino Murakami ; Kai Fenzl ; Hannah Vorgerd ; Florian Erhard ; Samie R Jaffrey ; Sebastian A Leidel ; Lars M SteinmetzSeries Type : OtherOrganism : Homo sapiensChemically modified mRNA nucleotides are emerging as key regulators of gene expression. Their effects are typically thought to be mediated thro […]
- GSE238204 Peak analysis of small cell-free RNA in oral cancer plasma finds recurrently protected narrow regions with clinical potential May 9, 2025Contributors : Pengfei Bao ; Shaozhen Xing ; Qing ZhanSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensOral cancer is characterized by poor prognosis and low survival rate despite sophisticated surgical and radiotherapeutic modalities. Lymphatic metastasis of oral cancer is a complex process involving multiple post-t […]
- GSE268431 Cellular senescence in skeletal muscle aging: new mechanisms and therapeutic potential for sarcopenia [cut&run_seq_IMR90] May 9, 2025Contributors : Huating Wang ; Yang Li ; Chuhan LiSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensSkeletal muscle allows voluntary movement and plays a key role in regulating metabolism and homeostasis in the organism. Adult muscle stem cells, MuSCs, are responsible for muscle growth and regeneration. Skele […]
- GSE248503 m6A is decoded by modified tRNAs to coordinate mRNA decay [RNA-Seq] May 9, 2025Contributors : Bastian Linder ; Puneet Sharma ; Shino Murakami ; Jie Wu ; Kai Fenzl ; Hannah Vorgerd ; Florian Erhard ; Samie R Jaffrey ; Sebastian A Leidel ; Lars M SteinmetzSeries Type : OtherOrganism : Mus musculusChemically modified mRNA nucleotides are emerging as key regulators of gene expression. Their effects are typically thought to be mediated thro […]
- GSE295748 Brg1 defect causes aberrent nucleosome landscape and affects totipotency & pluripotency transcriptional factors binding during embryogenesis May 9, 2025Contributors : Xinyu Wang ; Qi Shi ; Chong Li ; Shaorong Gao ; Xiaoyu LiuSeries Type : Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism : Mus musculusMammalian embryogenesis involves intricate epigenetic reprogramming and chromatin remodeling. In this study, we investigated the role […]
- GSE268952 Cellular senescence in skeletal muscle aging: new mechanisms and therapeutic potential for sarcopenia [RNA-seq] May 9, 2025Contributors : Huating Wang ; Yang Li ; Chuhan LiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSkeletal muscle allows voluntary movement and plays a key role in regulating metabolism and homeostasis in the organism. Adult muscle stem cells, MuSCs, are responsible for muscle growth and regeneration. Skeletal muscle suf […]
- GSE295896 Protein-primed DNA homopolymer synthesis by an antiviral reverse transcriptase [RIP-seq] May 9, 2025Contributors : Stephen Tang ; Rimantė Žedaveinytė ; Nathaniel Burman ; Shishir Pandey ; Josephine L Ramirez ; Louie M Kulber ; Tanner Wiegand ; Royce A Wilkinson ; Yanzhe Ma ; Dennis J Zhang ; George D Lampe ; Mirela Berisa ; Marko Jovanovic ; Blake Wiedenheft ; Samuel H SternbergSeries Type : OtherOrganism : Escherichia coli str. K-12 substr. MG1655Bacteria […]
- GSE295895 Protein-primed DNA homopolymer synthesis by an antiviral reverse transcriptase [cDIP-seq] May 9, 2025Contributors : Stephen Tang ; Rimantė Žedaveinytė ; Nathaniel Burman ; Shishir Pandey ; Josephine L Ramirez ; Louie M Kulber ; Tanner Wiegand ; Royce A Wilkinson ; Yanzhe Ma ; Dennis J Zhang ; George D Lampe ; Mirela Berisa ; Marko Jovanovic ; Blake Wiedenheft ; Samuel H SternbergSeries Type : OtherOrganism : Escherichia coli str. K-12 substr. MG1655Bacteria […]
- GSE295897 Protein-primed DNA homopolymer synthesis by an antiviral reverse transcriptase [RNA-seq] May 9, 2025Contributors : Stephen Tang ; Rimantė Žedaveinytė ; Nathaniel Burman ; Shishir Pandey ; Josephine L Ramirez ; Louie M Kulber ; Tanner Wiegand ; Royce A Wilkinson ; Yanzhe Ma ; Dennis J Zhang ; George D Lampe ; Mirela Berisa ; Marko Jovanovic ; Blake Wiedenheft ; Samuel H SternbergSeries Type : Expression profiling by high throughput sequencingOrganism : Esch […]
- GSE296147 Characterization of gene expression in epididymal white adipose tissue of mice fed a normal or high-fat diet. May 9, 2025Contributor : M KurodaSeries Type : Expression profiling by arrayOrganism : Mus musculusC57BL/6 male mice were started on a high-fat diet (60% fat) at 9 weeks of age. Seven weeks after the start of the high-fat diet (16 weeks of age), epididymal white adipose tissue was collected and total RNA was isolated by Trizol reagent. Thereby, we tried to measure Gene […]
- GSE296207 NHR-66 Regulates Cuticular Collagen Expression and Modulates C. elegans Adhesion to Predatory Fungi May 9, 2025Contributors : Yen-Ping Hsueh ; Han-Wen Chang ; Hung-Che LinSeries Type : Expression profiling by high throughput sequencingOrganism : Caenorhabditis elegansNHR-66, a nuclear hormone receptor in C. elegans, regulates cuticle collagen genes important for fungal adhesion. RNA-seq of wild-type and nhr-66 STOP-IN mutants exposed to Arthrobotrys oligospora reveal […]
- GSE269419 Molecular recording of cellular protein kinase activity with chemical labeling May 9, 2025Contributors : De-en Sun ; Siuwang Ng ; Yu Zheng ; Shu Xie ; Niklas Schwan ; Paula Breuer ; Dirk C Hoffmann ; Julius Michel ; Daniel D Azorin ; Kim E Boonekamp ; Frank Winkler ; Wolfgang Wick ; Michael Boutros ; Yulong Li ; Kai JohnssonSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensProtein kinases control most cellular […]
- GSE293558 SM22α-lineage stromal cells in perivascular adipose tissue contribute to abdominal aortic aneurysm May 9, 2025Contributors : Xiaoxi Pan ; Run Zhang ; Bingling Lu ; Siyuan Chen ; Hongjin Chen ; Mengyao Li ; Le Qin ; Zhiyun Song ; Yi Yang ; Zhe Wang ; Fuhua Yan ; Aijun Sun ; Fang Wu ; Lichi Zhang ; Jiguang Wang ; Tomasz J Guzik ; Pingjin GaoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBackground: Perivascular adipose tissue (P […]