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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE200957 Identification and characterization analysis of the different genes in Rag1-/- mouse injected with CD8+TSCM cells induced by CUS using RNA-seq April 18, 2025Contributors : Xiaoyu Yu ; Honghong YaoSeries Type : Expression profiling by high throughput sequencingOrganism : Whole RNA-sequencing analysis was performed and analyzed by Lc. Biotech Co. Ltd. (Hangzhou, China). hippocampus tissue from the PBS_WT group, PBS_Rag1-/- group, Ctr CD8+TSCM_Rag1-/- group, and CUS CD8+TSCM_Rag1-/- group were collected in TRIzol. […]
- GSE264231 MeRIP-seq analysis of replicative senescent MEFs and WI-38 cells April 18, 2025Contributors : Liqian Chen ; Zixin Chen ; Zhongjun Zhou ; Guoxiang JinSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Cellular senescence is the most intuitive manifestation of individual senescence, and m6A is one of the most common modifications in mRNA, playing an important role in regulating gene expression, splicing, R […]
- GSE231435 African swine fever infection epigenetically regulate host membrane protein-encoding genes April 18, 2025Contributors : Liangliang Fu ; Xiaolong Qi ; Yue Xiang ; Limeng Sun ; Jingjin Li ; Lu zhang ; Peng Zhou ; Zhuqing Zheng ; Qiulin Zhao ; Lingyu Xing ; SaiXian ZhangSeries Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencing ; OtherOrganism : African swine fever virus (ASFV) is a highly co […]
- GSE264386 cGAS Suppresses β-cell Proliferation by a STING-independent but CEBPβ-dependent Mechanism April 18, 2025Contributors : Zixin Cai ; Jingjing ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Aims/hypothesis cGAS (cyclic GMP-AMP synthase) has been implicated in various cellular processes, but its role in β-cell proliferation and diabetes is not fully understood. This study investigates the impact of cGAS on β-cell proliferation, par […]
- GSE264369 Fatty acid oxidation downregulation in alveolar epithelial 2 cells promotes acute lung injury in obesity April 18, 2025Contributors : E Kallinos ; Kuei-Pin Chung ; Lisa K Torres ; Divya Bhatia ; Baran Ersoy ; William Z Zhang ; Heather Stout Delgado ; Augustine M Choi ; Maria PlatakiSeries Type : Expression profiling by high throughput sequencingOrganism : Obesity is associated with increased risk for acute respiratory distress syndrome (ARDS). High fat diet induced obesity w […]
- GSE287596 Transcriptomic response of apple (Malus x domestica Bork. cv. Húsvéti rozmaring) shoot explants to in vitro cultivation on media containing thidiazuron or 6-benzylaminopurine riboside April 18, 2025Contributors : Dóra Farkas ; Viktor Ambrus ; Anita Király ; Neama Abdalla ; Judit DobránszkiSeries Type : Expression profiling by high throughput sequencingOrganism : The effects of two cytokinins (thidiazuron and 6-benzylaminopurine riboside), each applied at 4.5 μM, were studied on mRNA transcription of in vitro apple shoots. Transcriptomic response was in […]
- GSE268121 RNA-seq Analysis of the Longissimus Muscle of Laiwu and Yorkshire Pigs April 18, 2025Contributors : Wen C Peng ; Jiang W WuSeries Type : Expression profiling by high throughput sequencingOrganism : Intramuscular fat (IMF) content is the determining factor for meat taste. To reveal the genetic basis of IMF content, genetic studies have made some progress in lean-type pig breeds, but fewer studies have been conducted in Chinese fat-type pigs. […]
- GSE294399 Rare Subset of T Cells Form Integrin-dependent Clustering with Circulating Tumor Cells to Foster Metastasis in Breast Cancer April 18, 2025Contributors : David Scholten ; Andrew D Hoffmann ; Matthew Schipma ; Priyam Patel ; Ching Man Wai ; Huiping LiuSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : The immune ecosystem, particularly T cells, is central to maintaining effective anti-tumor responses. However, how immune cells in the periphery blood interact with […]
- GSE294410 The “play transcriptome” is sex-specific in the juvenile rat medial amygdala: a role for inhibitory neurons April 18, 2025Contributors : Ashley E Marquardt ; Mahashweta Basu ; Jonathan W VanRyzin ; Seth A Ament ; Margaret M McCarthySeries Type : Expression profiling by high throughput sequencingOrganism : Social play is a well-conserved, dynamic behavior known to be sexually differentiated. In most species, males play more than females, a sex difference largely driven by the me […]
- GSE294498 Incorporating programmable DNA-binding domains enhances the efficiency and flexibility of miniature CRISPR base editors April 18, 2025Contributors : Qianyue Huang ; Geng LiSeries Type : Expression profiling by high throughput sequencingOrganism : The therapeutic application of base editors is currently limited by their large sizes, which are often beyond the packaging capabilities of adeno-associated viral (AAV) vectors. Despite recent progress in mega genome mining that has identified a d […]
- GSE294611 TSG-6 activated MSC-derived Extracellular Vesicles present altered micro-RNA contents and ameliorate the inflammatory phenotype of macrophages in vitro April 18, 2025Contributors : Iker Martinez-Zalbidea ; Alyssa Rzasa ; Varun Puvanesarajah ; Wolfgang Hitzl ; Karin Wuertz‑KozakSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have shown promising immunomodulatory properties; however, strategies to enhance their therapeutic potenti […]
- GSE294910 Serotonin Gates Hippocampal VIP Interneuron Activation in Novelty Detection via Dual-Transmitter MnR Signaling April 18, 2025Contributors : Xiao Luo ; Dimitry Topolnik ; Justine Fortin-Houde ; Felix Michaud ; Benedicte Amilhon ; Lisa TopolnikSeries Type : Expression profiling by high throughput sequencingOrganism : We sequenced thirteen vasoactive intestinal peptide (VIP)-expressing interneurons from the mouse CA1 oriens/alveus area using patch-seq technique to determine their mol […]