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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE280296 Sequential transcriptional programs underpin activation of quiescent hippocampal stem cells. March 16, 2025Contributors : Piero Rigo ; Sara Ahmed de Prado ; Rebecca Johnston ; Chandra Choudhury ; François Guillemot ; Lachlan HarrisSeries Type : Expression profiling by high throughput sequencingOrganism : Postnatal neural stem cells are primarily quiescent, which is a cellular state that exists as a continuum from deep to shallow quiescence. The molecular changes […]
- GSE262245 NEST: Spatially-mapped cell-cell communication patterns using a deep learning-based attention mechanism March 16, 2025Contributors : Fatema Tuz Zohora ; Eugenia Flores-Figueroa ; Joshua Li ; Deisha Paliwal ; Faiyaz Notta ; Gregory W SchwartzSeries Type : OtherOrganism : Dysregulation of communication between cells mediates complex diseases such as cancer and diabetes. However, detecting cell-cell communication (CCC) at scale remains one of the greatest challenges in transcr […]
- GSE287948 Let-7 restrains an oncogenic epigenetic circuit in AT2 cells to prevent ectopic formation of fibrogenic cell intermediates and pulmonary fibrosis [RNA-seq] March 16, 2025Contributors : Antony Rodriguez ; Cristian CoarfaSeries Type : Expression profiling by high throughput sequencingOrganism : Analysis of lung alveolar type 2 (AT2) progenitor stem cells has highlighted fundamental mechanisms that direct their differentiation into alveolar type 1 cells (AT1s) in lung repair and disease. However, microRNA (miRNA) mediated post- […]
- GSE282419 Dbf4-Dependent Kinase Finetunes INO80 Function at Chromosome Replication Origins March 16, 2025Contributors : Priyanka Bansal ; Shibojyoti Lahiri ; Chandni Kumar ; Lorenzo Galanti ; Erika Chacin ; Jessica Furtmeier ; Garp Linder ; María A Ortíz-Bazán ; Marisa Müller ; Petra Vizjak ; Tobias Straub ; Felix Mueller-Planitz ; Johannes Stigler ; Andrés Aguilera ; Belen Gómez-González ; Boris Pfander ; Axel Imhof ; Christoph F KuratSeries Type : Genome bind […]
- GSE198766 The regulatory mechanisms of SIS3 on bone marrow-derived NK (BM-NK) cells under TGF-β stimulation using RNA sequencing March 16, 2025Contributors : Guang-Yu Lian ; Yingpeng Wan ; Qing-Ming Wang ; Thomas S Mak ; Jinfeng Zhang ; Zi-Ying Wang ; Min Li ; Xiao-Ru Huang ; Chun-Sing Lee ; Xue-Qing Yu ; Hui-Yao LanSeries Type : Expression profiling by high throughput sequencingOrganism : To explore the underlying mechanisms of SIS3 attenuating TGF-β-induced immunosuppression on NK cells, RNA-sequ […]
- GSE291760 FG repeats drive co-clustering of nuclear pores and P. granules in the C elegans germline [RNA-seq] March 16, 2025Contributors : Laura Thomas ; Devavrat Bodas ; Geraldine SeydouxSeries Type : Expression profiling by high throughput sequencingOrganism : Condensates that accumulate small RNA biogenesis factors (nuage) are common in germ cells and often associate with nuclei. In the C. elegans germline, P granules overlay large clusters of nuclear pores and this organizati […]
- GSE288807 Impaired methyl recycling induces substantial shifts in sulfur utilization in Arabidopsis (RNA-seq) March 16, 2025Contributors : Benjamin J Tremblay ; Saeer A Adeel ; Maye Saechao ; Yihan Dong ; Eric Andrianasolo ; John M Steele ; Annika Traa ; Nilanth Yogadasan ; Ishari Waduwara-Jayabahu ; Barbara A Katzenback ; Markus Wirtz ; Rüdiger Hell ; Barbara A MoffattSeries Type : Expression profiling by high throughput sequencingOrganism : The tight coordination of sulfur meta […]
- GSE198913 Single cell transcriptome of dermal sheath cup cells contributing to efficacy of cell-based therapy for patterned hair loss March 16, 2025Series Type : Expression profiling by high throughput sequencingOrganism : Autologous cell-based therapy using dermal sheath cup (DSC) cell is a new approach for male and female pattern hair loss. While its efficacy was recently reported, the mechanism of action remains unclear. Furthermore, the differences in treatment response require clarification. First, […]
- GSE288809 Impaired methyl recycling induces substantial shifts in sulfur utilization in Arabidopsis March 16, 2025Series Type : Expression profiling by high throughput sequencing ; Methylation profiling by high throughput sequencingOrganism : This SuperSeries is composed of the SubSeries listed below.
- GSE288808 Impaired methyl recycling induces substantial shifts in sulfur utilization in Arabidopsis (BS-seq) March 16, 2025Contributors : Benjamin J Tremblay ; Saeer A Adeel ; Maye Saechao ; Yihan Dong ; Eric Andrianasolo ; John M Steele ; Annika Traa ; Nilanth Yogadasan ; Ishari Waduwara-Jayabahu ; Barbara A Katzenback ; Markus Wirtz ; Rüdiger Hell ; Barbara A MoffattSeries Type : Methylation profiling by high throughput sequencingOrganism : The tight coordination of sulfur met […]
- GSE291456 Obesity hinders the efficacy of adipose-derived stem cells for knee osteoarthritis by reducing the proportion of DPP4+ stem cells March 16, 2025Series Type : Expression profiling by high throughput sequencingOrganism : Osteoarthritis (OA) is the most prevalent and disabling joint disease, while adipose-derived stem cells (ASCs) have emerged as a promising therapeutic option in pre-clinical studies. However, the therapeutic efficacy of ASCs may be influenced by the source of these cells, especially i […]
- GSE291612 Effect of photoperiod and seawater tranfer on transcriptome of saccus vasculosus from Atlantic salmon March 16, 2025Contributors : Alexander West ; Shona Wood ; Marianne Iversen ; Simen Sandve ; Even Jørgensen ; David HazleriggSeries Type : Expression profiling by high throughput sequencingOrganism : Atlantic salmon (Salmo salar) move from fresh- to seawater environments following a seasonally timed preparative transition called smoltification, which takes place under pho […]
- GSE291665 NF-kB signaling driven by oncogenic Ras contributes to tumorigenesis in a Drosophila carcinoma model March 16, 2025Contributors : Caroline Dillard ; Jose Teles Reis ; Ashish Jain ; Antunes Goncalves Antunes ; Yanyan Qi ; Roland Le Borgne ; Paula Ruiz Duran ; Heinrich Jasper ; Tor Erik RustenSeries Type : Expression profiling by high throughput sequencingOrganism : Cancer-driving mutations synergize with inflammatory stress signaling pathways during carcinogenesis. Drosop […]
- GSE202895 FMR1-dependent phenotypes March 16, 2025Series Type : Expression profiling by high throughput sequencingOrganism : This SuperSeries is composed of the SubSeries listed below.
- GSE287951 Let-7 restrains an oncogenic epigenetic circuit in AT2 cells to prevent ectopic formation of fibrogenic cell intermediates and pulmonary fibrosis March 16, 2025Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencing ; OtherOrganism : This SuperSeries is composed of the SubSeries listed below.