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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE292561 Single Cell Transcriptional Characterization of the Developing Organ of Corti Identifies Etv4/5/1 as Regulators of Lateral Cell Identity March 13, 2026Contributors : Susumu Sakamoto ; Robert J Morell ; Matthew W KelleySeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe mammalian auditory sensory epithelium, the organ of Corti, is comprised of a complex and highly ordered cellular mosaic that includes multiple unique cell types. The small number of each of these cell t […]
- GSE298703 Tpsb2-CreERT2 system did not alter mast cell viability or development March 13, 2026Contributors : Qingqing Li ; Wenwen ZengSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe selection of an appropriate Cre line is critical for ensuring the accuracy of cell type–specific investigations. We generated a Tpsb2-CreERT2 mouse line that enables precise and efficient labeling of target mast cells, with no de […]
- GSE293194 Plant hormone and peptide signaling converge in the genetic network regulating cambium activation in Arabidopsis roots. March 13, 2026Contributors : Tiina Blomster ; Riccardo Siligato ; Riikka Mäkilä ; Wiktoria Fatz ; Munan Lyu ; Maria Angels de Luis Balaguer ; Lingling Ye ; Iris Gildea ; Omid Safronov ; Panu Somervuo ; Kamil Růžička ; Jarkko Salojärvi ; Rossangela Sozzani ; Melis Kucukoglu Topcu ; Ari Pekka MähönenSeries Type : Expression profiling by high throughput sequencingOrganism : […]
- GSE304157 Discovery of a druggable site regulating DNA Binding of the AP1 transcription factor, deltaFOSb March 13, 2026Contributors : Sean McNeme ; Yun Young Yim ; Ashwani Kumar ; Yi Li ; Brandon Hughes ; Corey P St. Romain ; Galina Aglyamova ; Jianping Chen ; Nghi D Nguyen ; Shanghua Fan ; Gabriel S Stephens ; Wen-Ning Zhao ; Samantha Kruzshak ; Molly Estill ; Corrine Brener ; Solange Tofani ; Anil Kumar ; Earnest P Chen ; Alfred J Robinson ; Haiying Chen ; Reid T Powell ; […]
- GSE303531 CHI3L1 contributes to an immune suppressed tumour microenvironment in highly invasive brain metastases March 13, 2026Contributors : Sarah M Maritan ; Elham Karimi ; Matthew Dankner ; Aldo Hernandez-Corchado ; Miranda W Yu ; Matthew G Annis ; Yashar Aghazadeh-Habashi ; Morteza Rezanejad ; Bridget Liu ; Nebras Koudieh ; Emilie Pichette ; Benoit Fiset ; Yuhong Wei ; Ali Nehme ; Chun G Lee ; Jack A Elias ; Morag Park ; Yasser Riazalhosseini ; Hamed Najafabadi ; Kevin Petrecca […]
- GSE263670 Characterization of the dural meninges against viral infection March 13, 2026Contributors : Qingqing Li ; Wenwen ZengSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe meninges serve as a protective barrier for the brain and are essential in combating pathogen attacks, such as viral infections, that could otherwise result in fatal outcomes. To delineate the immune response during viral infectio […]
- GSE324781 ChIP-Seq with reference exogenous genome (ChIP-Rx) of MYC in parental U2OS cells March 13, 2026Contributors : Sihan Li ; Zehua Wang ; Da YangSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensEmerging evidence suggests that MYC binds RNAs, but its functional consequences remain unclear. Here, we integrate multi-omics data and reveal that MYC broadly binds enhancer RNAs (eRNAs), which exhibit high cance […]
- GSE324243 ST36 acupoint implantation of an astragaloside IV–glycyrrhizic acid drug eluting suture enhances immune function in weaned lambs by modulating the Treg/Th17 balance March 13, 2026Contributors : Hai Zhou ; Ke Zhou ; Zhizhen ZhaoSeries Type : Expression profiling by high throughput sequencingOrganism : Ovis ariesWeaning is a critical period in young animals and is often accompanied by immunosuppression and intestinal immune imbalance caused by stress and nutritional transition. In this study, an astragaloside IV- and glycyrrhizic acid- […]
- GSE324242 RNA binding proteins Pcbp1 and Pcbp2 are indispensable for B cell development [scRNA-seq ko] March 13, 2026Contributors : Xing Chang ; Li Lin ; Tuan Qi ; Geng LiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusB-cell development in the bone marrow is a tightly regulated process requiring precise control of gene expression at both transcriptional and post-transcriptional levels. Here, we identify the RNA-binding proteins Pcbp1 […]
- GSE324475 Transcriptional profiling of CRP-V5 and K52Q-V5 Vibrio cholerae C6706 grown in M9 minimal medium with maltose or trehalose as sole carbon source March 13, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Vibrio cholerae C6706RNA-seq was performed to compare the transcriptomes of Vibrio cholerae C6706 strains expressing V5-tagged wild-type CRP (CRP-V5) or the acetylation-mimicking mutant K52Q-V5 during growth in M9 minimal medium supplemented with 0.8% maltose or 0.8% trehalose as the […]
- GSE324277 miRNA Expression data from human heatstroke patients March 13, 2026Contributors : Abderrezak Bouchama ; Saeed Al Mahri ; Maria GomezSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensThis study examined miRNA responses to heat exposure in peripheral blood mononuclear cells from 19 patients with heat stroke and 19 controls.
- GSE324653 HIV-1 Amplifies IL-8 Response Of Human Stellate Cells To Gram-Positive Microbial Products Via H4K5 Histone Acetylation March 13, 2026Contributors : Lumin Zhang ; Rabab O Ali ; Naichaya Chamroonkul ; Parissa Tabrizia ; Myron Schwart ; Ganesh Gunasekaran ; Maria Isabel Fiel ; Thomas Schiano ; Steven C Ward ; Meena B BansalSeries Type : Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism : Homo sapiensPatients living w […]
- GSE324668 Single-nucleus transcriptomic profiling of mouse hearts following angiotensin II-infused with or without bisphenol F (BPF) treatment. March 13, 2026Contributors : Jing Wang ; Jie Xu ; Huanzhuo Mai ; Guolei Niu ; Shenshen Wu ; Xianan Zhang ; Jiahao Zhu ; Michael Aschner ; Qingtao Meng ; Rui ChenSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBisphenol F (BPF) is a widely used substitute for bisphenol A (BPA) in plastic manufacturing; however, its potential toxicity […]
- GSE324751 A scalable human-zebrafish xenotransplantation model reveals gastrosome-mediated processing of dying neurons by human microglia March 13, 2026Contributors : Ambra Villani ; Izaskun Mallona ; Francesca PeriSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensMicroglia engulf dying neurons through efferocytosis, a critical function in both development and disease. How microglia process the engulfed neuronal material—especially lipids—remains poorly understood, despi […]
- GSE291097 Depolymerizing F-actin accelerates the exit from pluripotency to enhance stem cell-derived islet differentiation [scRNA-Seq] March 13, 2026Contributors : Nathaniel Hogrebe ; Mason Schmidt ; Punn Augsornworawat ; Jeffrey MillmanSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensIn this study, we performed single-cell RNA sequencing and single-nuclei multiomic sequencing (RNA+ATAC) at various stages during the differentiation of human pluripotent stem cells to […]