NCBI Insights

NCBI Insights

• RefSeq Release 229 is Now Available! March 13, 2025
  Check out RefSeq release 229, now available online and from the FTP site. You can access RefSeq data through NCBI Datasets. The release is provided in several directories as a complete dataset and also as divided by logical groupings. What’s included in this release? As of March 3, 2025, this full release incorporates genomic, transcript, and protein data co […]
  NCBI Staff
• GenBank Release 265.0 Now Available! March 11, 2025
  GenBank release 265.0 (3/8/2025) is now available on the NCBI FTP site. This release has 41.96 trillion bases and 5.56 billion records. The current release has:  255,669,865 traditional records containing 5,415,448,651,743 base pairs of sequence data 4,152,691,448 WGS records containing 35,643,977,584,264 base pairs of sequence data 961,491,801 bulk-oriented […]
  NCBI Staff
• New Ranks in NCBI Taxonomy: Domain & Realm February 27, 2025
  As previously announced, NCBI continues to make improvements to our Taxonomy resource. There have been recent updates to the International Code of Nomenclature of Prokaryotes (ICNP) and proposals by the International Committee on Taxonomy of Viruses (ICTV). As a result, NCBI Taxonomy has discontinued the use of rank “superkingdom” to classify organisms into […]
  NCBI Staff
• New! Introducing the Multiple Comparative Genome Viewer (MCGV) Beta Release January 16, 2025
  NLM’s NCBI is excited to introduce the Multiple Comparative Genome Viewer (MCGV), a new tool in active development that allows you to visualize an alignment of multiple eukaryotic genomes. While our existing Comparative Genome Viewer (CGV) allows you to compare pairs of eukaryotic assemblies, the new MCGV tool can help you analyze multiple assemblies in … Co […]
  NCBI Staff
• An updated bacterial and archaeal reference genome collection is available! January 14, 2025
  Download the updated bacterial and archaeal reference genome collection! We built this collection of 21,258 genomes by selecting the “best” genome assembly for each species among the 400,000+ prokaryotic genomes in RefSeq. What’s new? As previously announced, we updated our release process: There is now an incremental process. In addition to quarterly releas […]
  NCBI Staff
• NCBI Resources Highlighted in 2025 Nucleic Acids Research Database Issue January 13, 2025
  The 2025 Nucleic Acids Research Database Issue features papers from NCBI staff on ClinVar, PubChem, GenBank, RefSeq, and more. The citations are available in PubMed with full-text available in PubMed Central (PMC). To read an article, click on the PMCID number listed below.  Database resources of the National Center for Biotechnology Information in 2025 PMCI […]
  NCBI Staff
• RefSeq Release 228 is Available! January 10, 2025
  Check out RefSeq release 228, now available online and from the FTP site. You can access RefSeq data through NCBI Datasets. The release is provided in several directories as a complete dataset and also as divided by logical groupings. What’s included in this release? As of January 3, 2025, this full release incorporates genomic, transcript, and protein data […]
  NCBI Staff
• Access Avian Influenza A (H5N1) Virus Sequences from the Current Outbreak at NCBI January 8, 2025
  The U.S. Centers for Disease Control and Prevention (CDC) has been monitoring the ongoing outbreak of the avian influenza A (H5N1) virus. This is widespread globally in wild birds, and has led to sporadic outbreaks in poultry, cows, several species of wild animals, and has been detected in exposed humans. The CDC recently sequenced the … Continue reading Acc […]
  NCBI Staff
• Top of 2024: A Look at the NCBI Insights Blog  January 6, 2025
  As we begin a new year, let’s look back at the top NCBI Insights Blog posts of 2024 based on number of views.   In case you missed any of these, check them out:  Learn more The NCBI Insights Blog is intended to help you better understand NCBI and our resources, explore issues of scientific interest … Continue reading Top of 2024: A Look at the NCBI Insights […]
  NCBI Staff
• GenBank Release 264.0 Now Available! December 23, 2024
  GenBank release 264.0 (12/19/2024) is now available on the NCBI FTP site. This release has 38.97 trillion bases and 5.36 billion records. The current release has:  254,365,075 traditional records containing 5,085,904,976,338 base pairs of sequence data 3,957,195,833 WGS records containing 32,983,029,087,303 base pairs of sequence data 957,403,887 bulk-orient […]
  NCBI Staff