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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE207535 RNA sequencing of neonatal mouse liver July 5, 2025Contributors : Lijun Yang ; Yujia Wang ; Mingyang Li ; Jie Hao ; Xiuyuan Sun ; Rong Jin ; Hounan Wu ; Xuyu Zhou ; Qing GeSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusLiver development in neonatal mice with T-bet+ Tregs deletion was detected by RNA-seq.
- GSE301539 Serum microRNA Profiling at an Early and Late Stages of Rotenone-Induced Parkinson’s Disease in Rats July 5, 2025Contributors : Pankaj S Dholaniya ; Mohammad Ahmad ; Md Zainul Ali ; Neha S ; Prashant Kumar ; Ranjitha Gadicherla ; Vengala Rao YenugantiSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Rattus norvegicusThis study investigates alterations in serum microRNA (miRNA) expression during the early (10-day) and late (terminal) stages […]
- GSE208263 Landscape of CD4+Foxp3+ Treg cells in the liver of neonatal mice July 5, 2025Contributors : Lijun Yang ; Yujia Wang ; Mingyang Li ; Jie Hao ; Xiuyuan Sun ; Rong Jin ; Hounan Wu ; Xuyu Zhou ; Qing GeSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo study the heterogeneity of regulatory T cells (Tregs) in various organs, we performed single-cell RNA sequencing on liver and splenic Treg cells obta […]
- GSE207656 PAR-iCLIP MCMV infection July 5, 2025Contributors : Anne L'Hernault ; Andrzej Rutkowski ; Jernej Ule ; Florian Erhard ; Lars DölkenSeries Type : OtherOrganism : Mus musculusSwiss murine embryonic fibroblasts (NIH-3T3) or murine TCMK-1 epithelial cells were infected with BAC-derived wild-type Smith strain mouse cytomegalovirus (MCMV) at a multiplicity of infection (MOI) of 10. PAR-iCLIP was […]
- GSE245643 Xist upstream deletion leads to dysregulation of Xist and autosomal gene expression July 5, 2025Contributors : Sudeshna Majumdar ; Lakshmi S Bammidi ; Hemant C Naik ; Avinchal Manhas ; Runumi Baro ; Akash Kalita ; Amlan J Naskar ; Nidharshan Sundarraj ; Girija S Bariha ; Dimple Notani ; Srimonta GayenSeries Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencing ; OtherOrganism : Mus […]
- GSE236843 Single cell level characterization of injury-induced immune changes in 10-week-old and 95-week-old C57BL/6 knee joints July 5, 2025Contributors : Aimy Sebastian ; Gabriela LootsSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPost-traumatic Osteoarthritis (PTOA) occurs in about half of individuals who sustained articular injuries including tibial plateau fracture, meniscus tear, or an anterior cruciate ligament (ACL) rupture. Damage-associated molec […]
- GSE301228 A Simple and Efficient Method for the Robust Expansion of Human ILC2s to Prevent Acute GvHD [RNA-seq] July 5, 2025Contributors : Danny W Bruce ; Sonia J Laurie ; Yan Xing ; Heather E Stefanski ; Keli L Hippen ; Alec D Wilkinson ; Mark G Woodcock ; James M Coghill Jr ; Karen P McKinnon ; Bruce R Blazar ; Jonathan S SerodySeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensReconstitution of stem cells and enhancement of the barrier funct […]
- GSE271507 Effect of complete abroagation of hyaluronan synthesis on osteogenic differentiation of mesenchymal stem cells (MSc) in vitro July 5, 2025Contributors : Anderegg Ulf ; Saalbach Anja ; Krohn KnutSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMesenchymal stem cells (MSc) show diminished osteogenic differentiation upon complete knockout of all known Hyaluronan (HA) synthases (Has). We demonstrated that Has-knockout completely abrogated the release of HA int […]
- GSE301286 Multimodal antigenic escape to GPRC5D-targeted T-cell engagers in multiple myeloma [scRNA-seq] July 5, 2025Contributors : Holly Lee ; Noémie Leblay ; Sungwoo Ahn ; Sacha Benaoudia ; Elham Hasheminasabgorji ; Mansour Poorebrahim ; David Jung ; Paola Neri ; Nizar BahlisSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTumor intrinsic adaptations with emerging resistant clones following T cell targeted immunotherapies pose a majo […]
- GSE301275 A Simple and Efficient Method for the Robust Expansion of Human ILC2s to Prevent Acute GvHD July 5, 2025Series Type : Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
- GSE301287 Multimodal antigenic escape to GPRC5D-targeted T-cell engagers in multiple myeloma [scATAC-seq] July 5, 2025Contributors : Holly Lee ; Noémie Leblay ; Sungwoo Ahn ; Sacha Benaoudia ; Elham Hasheminasabgorji ; Mansour Poorebrahim ; David Jung ; Paola Neri ; Nizar BahlisSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensTumor intrinsic adaptations with emerging resistant clones following T cell targeted immunotherapi […]
- GSE301313 Transcriptional differences in jejunum and ileum of a conditional knockout of Dab2 in the intestine July 5, 2025Contributors : Block Carina L ; Bagnat Michel ; Eroglu Cagla ; Sakers KristinaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe report bulk RNAseq data obtained from P6 mice. Input was isolated epithelium cells of the small intestine in a 2cm segment of the jejunum and 2 cm segment in the ileum of P6 Dab2 cWT and Dab2 […]
- GSE301510 Single-cell level gene expression profiles of adult Drosophila midguts with lineage tracing targeting enteroendocrine cells July 5, 2025Contributors : Qingyin Qian ; Yuya Sanaki ; Ryusuke NiwaSeries Type : Expression profiling by high throughput sequencingOrganism : Drosophila melanogasterDifferentiated cells exhibit cellular plasticity,where they dedifferentiate into stem cells. We studied cellular plasticity of secretory enternendocrine cells (EEs) in the fruit fly Drosophila melanogaster. […]
- GSE271703 Integrated ChIP-seq and Transcriptomic Profiling of Histone Modifications Across Breast Cancer Progression in MCF10A-Derived Cell Lines [ChIP-Seq] July 5, 2025Contributors : Seth Frietze ; Cong GaoSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensCancer arises from complex epigenetic mechanisms that drive tumorigenesis. Gene regulatory elements play a pivotal role in reprogramming gene expression patterns, facilitating tumor initiation, progression, and metastasis […]
- GSE301227 A Simple and Efficient Method for the Robust Expansion of Human ILC2s to Prevent Acute GvHD [ATAC-seq] July 5, 2025Contributors : Danny W Bruce ; Sonia J Laurie ; Yan Xing ; Heather E Stefanski ; Keli L Hippen ; Alec D Wilkinson ; Mark G Woodcock ; James M Coghill Jr ; Karen P McKinnon ; Bruce R Blazar ; Jonathan S SerodySeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensReconstitution of stem cells and enhancement of the […]