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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE193951 To study the mechanism of BIP regulation gene in 143B cells using RNA-seq Analysis January 19, 2025Contributor : Tao ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensRNA-seq has developed to study the gene regulation mechanism. The goals of this study are to investigate the regulated potential genes of BIP.
- GSE194094 Interferon gamma-induction of TH1-like regulatory T cells controls anti-viral responses January 19, 2025Contributors : Angela M Gocher-Demske ; Jian Cui ; Dario A VignaliSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Mus musculusAbstract: Regulatory T cells (Tregs) are an immunosuppressive population that are required to maintain peripheral tolerance and prevent tissue damage during immunopathology, via anti-inflammatory cyt […]
- GSE194049 Effect of zinc on zerafish brain January 19, 2025Contributors : Fan Yu ; Zhi-Shuai Hou ; HongRui Luo ; XueFan CuiSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioWe evaluated the effect of zinc on zebrafish brain via single cell analysis
- GSE225056 Transcriptional profiling of mammalian preimplantation embryos January 19, 2025Contributors : Marlies E Oomen ; Diego Rodriguez-Terrones ; Maria-Elena Torres-PadillaSeries Type : Expression profiling by high throughput sequencingOrganism : Bos taurus ; Macaca mulatta ; Mus musculus ; Oryctolagus cuniculus ; Sus scrofaWe developed an adapted version of Smart-seq2, which we call Smart-seq+5', to capture both internal transcript frag […]
- GSE194104 Single cell RNA-Seq of blood cells in an irradiated patient January 19, 2025Contributors : Shuyu Zhang ; Tao Yan ; Daojiang YuSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThis study aims to explore the cell clusters and mRNA expression at the single cell level in a irradiated patient. The patient was a nuclear accident patient exposed to an X-ray fluorescence spectrometer. In this study, the […]
- GSE282358 Modulation of calcium signalling on demand to decipher the molecular mechanisms of primary aldosteronism January 19, 2025Contributors : Bakhta Fedlaoui ; Maria-Christina Zennaro ; Sheerazed BoulkrounSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensBackground. Primary aldosteronism is the most common form of secondary hypertension. The most frequent genetic cause of aldosterone producing adenoma (APA) are somatic mutations in the potassium […]
- GSE241077 Human MAIT10 and MAIT17 profiles are effector states directed by the cytokine milieu January 19, 2025Contributors : Caroline Boulouis ; Elli Mouchtaridi ; Thomas Müller ; Jeffrey Y Mak ; David P Fairlie ; Peter Bergman ; Jakob Michaëlsson ; Jonas Halfvarsson ; Jenny Mjösberg ; Marcus Buggert ; Johan K SandbergSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensMucosa-associated invariant T (MAIT) cells are unconventional M […]
- GSE261414 Effects of AIF3 on gene expression in MEF cells January 19, 2025Contributors : Mi Zhou ; Weibo Luo ; Yingfei WangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusAIF3 splicing differentially affects gene expression involved in different pathways.
- GSE253784 Crk mediates Csk-Hippo signaling independently of Yap tyrosine phosphorylation to induce cell competition January 19, 2025Contributors : Hannan Abdul ; Wang Qian ; Wu Yihua ; Makrides Neoklis ; Qu Xiuxia ; Mao Junhao ; Que Jianwen ; Cardoso Wellington ; Zhang XinSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSrc family kinases (SFKs), including Src, Fyn and Yes, play important roles in development and cancer. Despite being first discovere […]
- GSE272511 Histone H3 lysine 9 tri-methylation is associated with pterygium January 19, 2025Contributors : Dahee Choi ; Ann-Yae Na ; Seok-Won Jeoung ; Yun-Hee Choi ; Nayoon Park ; Hyun-Sun Park ; Hyun-Shik Lee ; Dong-Hyung Cho ; Dong H Kim ; Hong-Yeoul RyuSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensPterygium, abnormal growths of conjunctival tissue onto the cornea, are common ocular surface c […]
- GSE269144 Extensive location bias of the GPCR-dependent translatome via site-selective activation of mTOR January 19, 2025Contributors : Matthew Klauer ; Katherine Hall ; Caitlin Jagla ; Nikoleta TsvetanovaSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Homo sapiensG protein-coupled receptors (GPCRs) modulate various physiological functions by re-wiring cellular gene expression in response to extracellular signals. Control of gene expression b […]
- GSE276114 Integrative proteo-transcriptomic characterization of advanced fibrosis in chronic liver disease across etiologies January 19, 2025Contributors : Mujdat Zeybel ; Dila Atak ; Adil Mardinoglu ; Hong YangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWhile technological advancements have improved our understanding of fibrogenesis, identifying advanced fibrosis in the general population remains challenging due to clinical heterogeneity influenced by u […]
- GSE278071 Smad2/3-mediated TGFβ signaling modulates neural crest developmental plasticity [RNA-seq] January 19, 2025Contributors : Megan Rothstein ; Ana Paula Azambuja ; Tatiane Y Kanno ; Catriona Breen ; Marcos Simoes-CostaSeries Type : Expression profiling by high throughput sequencingOrganism : Gallus gallusThe neural crest is a highly plastic stem cell population that represents a notable exception to the germ layer theory. Despite being of ectodermal origin, these ce […]
- GSE278072 Smad2/3-mediated TGFβ signaling modulates neural crest developmental plasticity [ATAC-seq] January 19, 2025Contributors : Megan Rothstein ; Ana Paula Azambuja ; Tatiane Y Kanno ; Catriona Breen ; Marcos Simoes-CostaSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Gallus gallusThe neural crest is a highly plastic stem cell population that represents a notable exception to the germ layer theory. Despite being of ectodermal or […]
- GSE175809 Smad2/3-mediated TGFβ signaling modulates neural crest developmental plasticity January 19, 2025Contributors : Megan Rothstein ; Tatiane Kanno ; Marcos Simoes-CostaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe neural crest is a highly plastic stem cell population that represents a notable exception to the germ layer theory. Despite being of ectodermal origin, these cells can differentiate into skeletal deriv […]