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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE241217 Transcriptional Responses to TREM2 Agonist Antibody Treatment in Cynomologus Monkey Brain December 5, 2024Series Type : Expression profiling by high throughput sequencingOrganism : Macaca fascicularisThis SuperSeries is composed of the SubSeries listed below.
- GSE225543 Metabolic Disruption in Zebrafish Larvae Due to Exposure to the Pesticides Tefluthrin or Acetochlor December 5, 2024Contributors : Fahmi Mesmar ; Maram Muhsen ; Jason Tourigny ; Jason Tennessen ; Maria BondessonSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioThis study investigates the pesticides' (Tefluthrin or Acetochlor) effects on gene expression
- GSE251796 Microbe-enhanced high light stress tolerance of Arabidopsis thaliana photosynthesis is coordinated through Iron-dependent redox metabolism December 5, 2024Contributors : Naganand Rayapuram ; Sabiha Parween ; Anam Fatima ; Heribert HirtSeries Type : Expression profiling by high throughput sequencingOrganism : Arabidopsis thalianaHigh light stress in subtropical and tropical regions strongly limits agricultural production due to photo-oxidative damage, decreased growth and yield. Here, we investigated whether be […]
- GSE246092 Transcriptional Responses to TREM2 Agonist Antibody Treatment in Cynomologus Monkey Brain - Study 2 December 5, 2024Contributors : Brad Friedman ; Gloriia Novikova ; Chang H Cho ; Anne Biever ; Alicia Nugent ; Yuxin LiangSeries Type : Expression profiling by high throughput sequencingOrganism : Macaca fascicularisMonkeys were treated with a single i.v 200 mg/kg dose of hPara.09 or Anti-gD (Isotype control). Brain was harvested on days 4 and 28, and RNA was extracted from […]
- GSE252440 DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs [rna_seq_kc_ddx50_kd] December 5, 2024Contributors : Weili Miao ; Douglas F Porter ; Paul A KhavariSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensGlucose, traditionally recognized as a primary energy source, has recently emerged as a key regulator of protein interactions, particularly when intracellular glucose levels increase during cellular differentiati […]
- GSE252329 DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs [rna_seq_stability_ddx50] December 5, 2024Contributors : Weili Miao ; Douglas F Porter ; Paul A KhavariSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensGlucose, traditionally recognized as a primary energy source, has recently emerged as a key regulator of protein interactions, particularly when intracellular glucose levels increase during cellular differentiati […]
- GSE282425 SenPred: A single-cell RNA sequencing-based machine learning pipeline to classify deeply senescent dermal fibroblast cells for the detection of an in vivo senescent cell burden December 5, 2024Contributors : Beth K Hughes ; Andrew Davis ; Deborah Milligan ; Ryan Wallis ; Federica Mossa ; Michael P Philpott ; Linda J Wainwright ; David A Gunn ; Cleo L BishopSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensBackground - Senescence classification is an acknowledged challenge within the field, as markers are cell-t […]
- GSE262298 Identification and Targeting of Regulators of SARS-CoV-2-Host interactions in the Airway Epithelium [scRNA-Seq] December 5, 2024Contributors : Brooke Dirvin ; Heeju Noh ; Lorenzo Tomassoni ; Danting Cao ; Yizhou Zhou ; Xiangye Ke ; Jun Qian ; Michael Schotsaert ; Adolfo Garcia-Saestre ; Charles Karan ; Andrea Califano ; Wellington V CardosoSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe conducting airway epithelium is the first line of defen […]
- GSE283199 NKp46 regulates type 1 innate lymphoid cell proliferation and function and anti-acute myeloid leukemia activity December 5, 2024Contributors : Jianhua Yu ; Zhenlong LiSeries Type : Expression profiling by high throughput sequencingOrganism : MusNKp46 is a critical regulator of natural killer (NK) cell immunity, but its function in non-NK innate immune cells remains unclear. Here, we show that NKp46 is indispensable for expressing IL-2 receptor-α (IL-2Rα) by non-NK liver-resident type […]
- GSE283115 Therapeutic Effects and Mechanisms of Pomegranate in the Treatment of Hyperlipidemia December 5, 2024Contributors : Hao Wang ; Xin Dong ; Caimeng Xu ; Shaonan Hu ; Yuewu Wang ; Peifeng XueSeries Type : Expression profiling by high throughput sequencingOrganism : RattusPomegranate exhibits pronounced hypolipidemic properties, and the objective of this study was to delineate the precise mechanism by which pomegranate facilitates the treatment of hyperlipidemi […]
- GSE283221 Identification of influenza virus-encoded vcircRNAs in human A549 cells by RNA-seq December 5, 2024Contributors : Wenliang Pan ; Yu ChenSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe discovery of noncoding RNAs is reshaping paradigms in molecular biology and virology. Circular RNAs (circRNAs), a class of novel noncoding RNAs, their circular conformation endows these transcripts with critical physiological and pa […]
- GSE283331 A single-cell plume transcriptome atlas of the cold-seep tubeworm Paraescarpia echinospica [ONT] December 5, 2024Contributors : Xianghui Zhang ; Yingying Zhang ; Nannan ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Paraescarpia echinospicaVestimentiferan tubeworms are representative inhabitants of deep-sea chemosynthetic ecosystems. The plume serves as the primary organ in these invertebrates without mouths and guts, facilitating direc […]
- GSE283471 The core cellular network modulates immune phenotype switching in hepatitis B December 5, 2024Contributors : Chuangeng Chen ; Ziqi Zhen ; Meng CuiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensHepatitis B virus (HBV) is a leading cause of liver-related diseases and mortality. However, immune mechanisms governing the phases of HBV infection remain elusive. Understanding molecular components in hepatitis immunosu […]
- GSE283473 Gene expression profile at single cell level of brain organoid at day56 of ctrl and WS December 5, 2024Contributors : Xingsen zhao ; Xue kun liSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensBrain organoid is consist of many different cells， We used single cell RNA sequencing (scRNA-seq) to analyze the diversity of each neural cluster in the intestine.
- GSE281644 Inorganic Pyrophosphate influence Stem Cells from Human Exfoliated Deciduous Teeth December 5, 2024Contributors : Ravipha Suwittayarak ; Nunthawan Nowwarote ; Chatvadee Kornsuthisopon ; Waleerat Sukarawan ; Brian L Foster ; Hiroshi Egusa ; Thanaphum OsathanonSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo explore the cellular response of stem cell derived from human exfoliated deciduous teeth (SHED) in response to […]