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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE253694 Pivotal Role of the NuRD Complex in Remodeling Chromatin Environment and Maintaining Genome Architecture at CTCF Sites [HEK293T_siNURD_CTCF_ChIP_Seq] May 4, 2026Contributors : Jian Yan ; Xi Wang ; Wenju Sun ; Nan WuSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensCCCTC-binding factor (CTCF) is an evolutionarily conserved transcription factor with diverse regulatory roles. Around stable CTCF binding sites, nucleosomes are highly ordered and DNA methylation is reduce […]
- GSE243570 Light sensitive short hypocotyl (LSH) confer symbiotic nodule identity in the legume Medicago truncatula May 4, 2026Contributors : Katharina Schiessl ; Tak LeeSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Medicago truncatulaLegumes produce specialized root nodules that are distinct from lateral roots in morphology and function, with nodules intracellularly hosting nitrogen-fixing bacteria. We have previously shown that a lateral […]
- GSE278193 Pivotal Role of the NuRD Complex in Remodeling Chromatin Environment and Maintaining Genome Architecture at CTCF Sites [mESC ChIP-seq] May 4, 2026Contributors : Jian Yan ; Xi Wang ; Wenju Sun ; Nan WuSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusCCCTC-binding factor (CTCF) is an evolutionarily conserved transcription factor with diverse regulatory roles. Around stable CTCF binding sites, nucleosomes are highly ordered and DNA methylation is reduce […]
- GSE266987 NAT10-mediated mRNA N4-acetylcytidine Modifications in Mouse Oocytes Constitute a Checkpoint of Ovarian Follicle Development [RIP-Seq] May 4, 2026Contributors : Wenjing Wang ; Yuke Wu ; Shaoyuan Liu ; Hengyu FanSeries Type : OtherOrganism : Mus musculusDuring mammalian follicular development, the correct establishment of the epitranscriptome in oocytes is essential for precise gene repression and the acquisition of developmental competence. N4-acetylcytidine (ac4C) is a conserved posttranscriptional R […]
- GSE297265 TRMT5/NES Coordinated Activity Drives Pancreatic Cancer Growth and Metastasis [RIP-seq II] May 4, 2026Contributors : Carlos A Melo ; Francisco J Campos-LaborieSeries Type : OtherOrganism : Homo sapiensPancreatic cancer is a disease of urgent unmet clinical need with a 94% death rate, predicted to become the second leading cause of cancer-related death by 2030. Despite increased efforts, effective therapies have not materialised. Here, we uncover a new molecu […]
- GSE284447 Cytotoxic Tissue-Resident NK Cells Infiltrate and Control Solid Epithelial Tumor Growth [CITE-Seq] May 4, 2026Contributors : John B Sunwoo ; Jennifer A Foltz ; Imran MohammadSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Homo sapiensHuman tissue-resident natural killer (trNK) cells – broadly defined by markers of tissue-residency, such as CD49a (integrin alpha1, ITGA1) and CD103 (integrin alpha E, ITGAE) – are increasingly recogni […]
- GSE329568 Transcriptomic of Visceral Adipose Tissue in HFD-induced obesity: evaluation of Resveratrol May 4, 2026Contributors : Monica Espinoza-Rojo ; Brenda De la Cruz-Concepción ; Yaccil Adilene Flores-Cortez ; Isela Parra-Rojas ; Juan Miguel Mendoza-BelloSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusVisceral adipose tissue (VAT) expansion during the development of obesity is a hallmark of metabolic syndrome, characterized by […]
- GSE173882 ELF5 regulates epithelial integrity independently of EHF [RNA-seq] May 4, 2026Contributors : Hannah Swahn ; Alekh Paranjapye ; Jey S Ebron ; James Browne ; Ann HarrisSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensE74-like ETS transcription factor 5 (ELF5) is one of three epithelial ETS family transcription factors. The ELF5 gene maps to chr11p13 where it is located adjacent to another epithelial […]
- GSE329692 Single-cell RNA analysis of allele-specific MHC expression in macaque PBMC after T cell activation or treatment with pro-inflammatory or anti-inflammatory cytokines May 4, 2026Contributors : Max C Ertl ; Roger W Wiseman ; Anthony J Veltri ; Julie A Karl ; Miranda R Stauss ; William K Gardner ; Nicholas R Minor ; David H O'ConnorSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Macaca fascicularis ; Macaca mulattaWe have employed a single-cell sequencing approach using 10X Genomics 5'scRNA […]
- GSE329678 Simvastatin Reprograms Lipid Metabolism in B16.F10 Melanoma Cells to Favor an Early Resistant Phenotype May 4, 2026Contributors : Giorgiana G Negrea ; Loredana Balacescu ; Ilie O Pavel ; Alina Sesarman ; Manuela BanciuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusOur previous studies demonstrated that simvastatin (SIM) inhibited B16.F10 murine melanoma cell proliferation in vivo and in vitro via strong suppressing the production o […]
- GSE329725 Differential Expression of microRNAs after Induction of Endometriosis in Baboons May 4, 2026Contributors : Ramanaiah Mamillapalli ; Hanna Surmann ; Niraj Joshi ; Gregory Burns ; Asgerally T Fazleabas ; Hugh S TaylorSeries Type : Expression profiling by high throughput sequencingOrganism : Papio anubisEndometriosis is an inflammatory chronic gynecological condition that affects 10-15% of reproductive-age women which causes pelvic pain and infertilit […]
- GSE329774 Metabolically and epigenetically reprogrammed splenic TRNP1hiCD8+ T cells exacerbate liver fibrosis May 4, 2026Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencing ; Methylation profiling by high throughput sequencing ; OtherOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE329794 H3K4me3 ChIPmentation-seq, human primary fibroblasts May 4, 2026Contributors : Jovan Isma ; Emery Di Cicco ; Gian-Paolo DottoSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensChromatin immunoprecipitation coupled with tagmentation followed by next-generation sequencing (ChIPmentation-seq) for histone H3 lysine 4 trimethylation (H3K4me3) was performed in human primary fib […]
- GSE215326 Pivotal Role of the NuRD Complex in Remodeling Chromatin Environment and Maintaining Genome Architecture at CTCF Sites [HEK293T_IAA72h_ChIP_Seq] May 4, 2026Contributors : Jian Yan ; Xi Wang ; Wenju Sun ; Nan WuSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensCCCTC-binding factor (CTCF) is an evolutionarily conserved transcription factor with diverse regulatory roles. Around stable CTCF binding sites, nucleosomes are highly ordered and DNA methylation is reduce […]
- GSE329567 Transcriptomic profiling of Visceral Adipose Tissue (VAT) in a neonatal STZ-induced diabetes model: modulatory effects of Curcumin. [RNA-Seq] May 4, 2026Contributors : Juan Miguel Mendoza-Bello ; Yaccil Adilene Flores-Cortez ; Brenda De la Cruz-Concepción ; Monica Espinoza-RojoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusVisceral Adipose Tissue (VAT) plays a pivotal role in the systemic metabolic complications of Type 2 Diabetes, acting as a primary site for pro-infl […]