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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE296277 Distinct tissue niches contribute to prostate TRM cell differentiation and heterogeneity [scRNA-seq] March 31, 2026Contributors : Kennidy Takehara ; Miguel Reina-Campos ; Ananda GoldrathSeries Type : Other ; Expression profiling by high throughput sequencingOrganism : Mus musculusThe prostate is an important exocrine organ, a barrier tissue of the male reproductive system, and a common site of malignancy, yet prostate CD8+ T cells remain largely uncharacterized. Here, we […]
- GSE303893 Single-nuclus RNA sequencing of stem cell-derived human trophoblast organoids cultured under simulated microgravity March 31, 2026Contributors : Shun Shibata ; Yuki Ishikawa ; Takahiro ArimaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensHuman placental development requires precise cellular differentiation, yet mechanistic understanding remains limited. Here, we perform single-nucleus RNA sequencing of day 11 human trophoblast organoids cultured u […]
- GSE299598 Spatial analysis reveals a novel inflammatory tumor transition state which promotes a macrophage-driven induction of sarcomatoid renal cell carcinoma [GeoMx] March 31, 2026Contributors : Allison May ; Evan KellerSeries Type : OtherOrganism : Homo sapiensSarcomatoid renal cell carcinoma (sRCC) is an aggressive trans-differentiation of epithelioid clear cell RCC (ccRCC) tumors that shows heightened response to immunotherapy. The underlying biology leading to sarcomatoid transformation and mechanisms contributing to immunotherapy […]
- GSE267884 Foxp3 and BATF cooperatively direct cis-regulatory programs and gene expression for effector Treg cell differentiation [scMultiome] March 31, 2026Contributors : Ryuichi Murakami ; Shohei HoriSeries Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusMechanisms by which diverse transcription factors (TFs), particularly the master regulator Foxp3, shape the heterogeneous transcriptional and epigenetic landscap […]
- GSE158397 Expression data from intraperitoneal injection of ovalbumin (OVA) sensitized allergy animal model March 31, 2026Contributor : Yongning LiSeries Type : Non-coding RNA profiling by arrayOrganism : Mus musculus ; synthetic constructIt is known that immune system can be regulated by miRNAs, thus we hypothesized that certain miRNAs may have a potential regulatory effect on the IgE mediated food allergy.In our study, the spleens of allergic mice induced by OVA were used for […]
- GSE292436 RNA sequences from mouse heart and gastrocnemius muscle March 31, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusRNA sequences from mouse heart and gastrocnemius muscle
- GSE287223 Circulating microRNAs as predictive biomarkers for progestin treatment response in endometriosis patients March 31, 2026Contributors : Antonella Ravaggi ; Stefano CalzaSeries Type : Expression profiling by RT-PCROrganism : Homo sapiensTotal RNA was extracted from 400 ul of serum with the miRNeasy Serum/Plasma advanced Kit (Qiagen) and quantified using the Qubit microRNA assay kit (Thermo Fisher Scientific). cDNA templates were prepared using the TaqMan Advanced miRNA cDNA Syn […]
- GSE326326 Spatiotemporal transcriptome atlas of human embryos after gastrulation March 31, 2026Contributors : Jiexue Pan ; Yuejiao Li ; Zhongliang Lin ; Qing Lan ; Ying Zhang ; Huixi Chen ; Shengwei Sui ; Man Zhai ; Lijian Zhao ; Hongbo Yang ; Ya Gao ; Guolian Ding ; Xun Xu ; Hefeng HuangSeries Type : OtherOrganism : Homo sapiensThe comprehensive spatiotemporal atlas of gene expression during early human embryonic development is critical for insights […]
- GSE326106 Long-read RNA-seq of human (Homo sapiens), gorilla (Gorilla gorilla), orangutan (Pongo abelii) and cynomolgus macaque (Macaca fascicularis) induced pluripotent stem cell and neural precursor cell lines March 31, 2026Contributors : Geuder Johanna ; Stefan Krebs ; Spurk Paulina ; Térmeg Anita ; Enard Wolfgang ; Hellmann InesSeries Type : Expression profiling by high throughput sequencingOrganism : Gorilla gorilla ; Homo sapiens ; Macaca fascicularis ; Pongo abeliiWe generated Oxford Nanopore long-read RNA-seq data to compare transcript isoform usage across four primate sp […]
- GSE326391 Genome-wide DNA methylation profiling in patient-derived airway basal cells and differentiated 3D bronchial organoids March 31, 2026Contributors : Felix Ritzmann ; Christoph Beisswenger ; Gilles GasparoniSeries Type : Methylation profiling by genome tiling arrayOrganism : Homo sapiensGenome-wide DNA methylation profiling was performed in patient-derived airway basal cells and differentiated 3D bronchial organoids to assess smoking- and COPD-associated epigenetic changes.
- GSE326348 GW4064-induced genes in mouse livers March 31, 2026Contributor : Yanqiao ZhangSeries Type : Expression profiling by arrayOrganism : Mus musculusFxr+/+ or Fxr-/- mice were gavaged with vehicle or GW4064 (30 mg/kg, twice a day) for 7 days. Livers were collected.Hepatic mRNA levels were determined using Sentrix MouseRef-8 v2 Expression BeadChip.
- GSE326495 Integrative single cell RNA and spatial profiling identify mechanisms of neonatal brain hemorrhage pathophysiology and repair [scRNA-seq] March 31, 2026Contributors : Santiago A Forero ; Zhihua Chen ; Ali Pirani ; Arpan De ; Zachary Wise ; Xiaofeng Zheng ; John E Morales ; Joseph H McCartySeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusHere we employed fixed single cell RNA profiling coupled with spatial in situ gene expression profiling to characterize NVU signaling p […]
- GSE326496 Integrative single cell RNA and spatial profiling identify mechanisms of neonatal brain hemorrhage pathophysiology and repair [Xenium] March 31, 2026Contributors : Santiago A Forero ; Zhihua Chen ; Ali Pirani ; Arpan De ; Zachary Wise ; Xiaofeng Zheng ; John E Morales ; Joseph H McCartySeries Type : OtherOrganism : Mus musculusHere we employed fixed single cell RNA profiling coupled with spatial in situ gene expression profiling to characterize NVU signaling pathways associated with ICH in Itgb8/β8 integ […]
- GSE326505 Differential gene expression drives cell-cycle-dependent transition from monopolar to bipolar growth in fission yeast March 31, 2026Contributors : Samridhi Pathak ; Maitreyi DasSeries Type : Expression profiling by high throughput sequencingOrganism : Schizosaccharomyces pombeIn S. pombe, cells transition from monopolar to bipolar growth in a cell cycle-dependent manner. To investigate this, we performed RNA-seq analysis of the cell-cycle mutant cdc10-129 to identify distinct gene expres […]
- GSE295181 HIF2ɑ Requires Engagement with YAP/TAZ and AP-1 Transcription Factors to Maintain Oncogenic Transcription in Clear Cell Renal Cell Carcinoma [RNA-Seq] March 31, 2026Contributors : Alec T McIntosh ; Ting Wang ; Shannon M White ; Shigekazu Murakami ; Benjamin A Colon-Emeric ; Sabina Signoretti ; James Brugarolas ; Michael B Atkins ; Chunling YiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensClear Cell Renal Cell Carcinoma (ccRCC) is characterized by loss of tumor suppressor von Hippe […]