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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE288573 Cigarette smoke and biological age induce degenerative heterogeneity in retinal pigment epithelium January 3, 2026Contributors : Yang Jin ; Krishna Singh ; Jiang Qian ; James T HandaSeries Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusEnvironmental exposure such as cigarette smoke induces epigenetic changes that can induce degenerative heterogeneity and accelerate aging. […]
- GSE293983 Cigarette smoke and biological age induce degenerative heterogeneity in retinal pigment epithelium [scRNA-seq] January 3, 2026Contributors : Yang Jin ; Krishna Singh ; Jiang Qian ; James T HandaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensEnvironmental exposure such as cigarette smoke induces epigenetic changes that can induce degenerative heterogeneity and accelerate aging. In early age-related macular degeneration (AMD), the leading world […]
- GSE309910 Cellular Mg2+ decrease causes a distinctive NF-κB-dependent form of cell death January 3, 2026Contributors : Koyuki Kawamura ; Yosuke Funato ; Hiroaki MikiSeries Type : Expression profiling by high throughput sequencingOrganism : Canis lupus familiarisMg2+ is an essential cofactor for numerous enzymes, supporting fundamental cellular processes. Phosphatase of regenerating liver (PRL) protein family, inhibits cyclin M (CNNM) Mg2+ efflux transporters. […]
- GSE310588 Impact of copper on the physiology and transcriptome of Methylosinus trichosporium OB3b grown on either methane or methanol January 3, 2026Contributors : Peng Peng ; Jeremy D SemrauSeries Type : Expression profiling by high throughput sequencingOrganism : Methylosinus trichosporium OB3bThis study investigates the combined effects of copper availability and carbon source (methane versus methanol) on the physiology and transcriptome of Methylosinus trichosporium OB3b, a model Type II methanotroph […]
- GSE315017 Identification and profiling of microRNAs in the midgut of Laodelphax striatellus after rice black-streaked dwarf virus (RBSDV) infection January 3, 2026Series Type : Non-coding RNA profiling by high throughput sequencingOrganism : Laodelphax striatellusMicroRNAs (miRNAs) are endogenous small noncoding RNAs (18–25 nt) that are involved in many physiological processes including development, cancer, immunity, apoptosis and host-microbe interactions through posttranscriptional regulation of gene expression. In […]
- GSE315475 Mice with targeted deletion of the Vasoactive Intestinal Peptide (VIP) gene have spontaneous pulmonary arterial hypertension exaggerated with hypoxia January 3, 2026Contributors : Akash Gupta ; Mohamed Ahmed ; Anthony N SzemaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe earlier reported spontaneous moderate pulmonary arterial hypertension in Vasoactive Intestinal Peptide (VIP) gene knockout mice. In the current study, we show accelerated pulmonary artery pressure changes assoc […]