Quick Links : Search PubMed , Finding Full Text , PubMed Advanced Search , Clinical Queries , Single Citation Matcher , FAQs & User Guide , Explore MeSH Database , Explore PubMed Journals
Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE306460 Evaluation of PTBP1 binding at transcripts in the human acute myeloid leukemia cell line MOLM-13 August 10, 2026Contributors : Zhendong Cao ; Kurtis N McCannell ; Junwei ShiSeries Type : OtherOrganism : Homo sapiensRNA-modifying enzymes (RNAes) and RNA-binding proteins (RBPs) have emerged as critical gene regulators in both normal physiology and cancer. To systematically evaluate their necessity in cancer, we performed domain-focused CRISPR screens targeting RNAes and […]
- GSE318813 E11.5 Branchial Arches RNA-seq from controls and Ehmt1/2 neural crest knockouts August 10, 2026Contributors : Diana B Fulmer ; Emily J Shields ; Cheryl L Smith ; Rajan Jain ; Jonathan A EpsteinSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusGLP and G9a repress alternative fate pathways in the neural crest. Analyses of transcript profiles from 3 control (Ehmt1+/+, Ehmt2+/+, Rosa26 TdTomato/+, Wnt1-cre) and 3 DKO ( […]
- GSE310980 Roles of RNF213 in temporal resonse to palmitate in HeLa cells August 10, 2026Contributors : Qianying Huang ; Kei Iida ; Tohru TezukaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe aimed to study roles of RNF213 in palmitate-induced signaling pathways using RNF213-knockout HeLa cells.
- GSE327709 Transient cell states encode positional information to direct asymmetric growth [MERFISH] August 10, 2026Contributors : Travis A Lee ; Kamonkan Gamnerdsiri ; Natanella Illouz-Eliaz ; Tatsuya Nobori ; Joseph R Nery ; Bruce Jow ; Michelle Liem ; Caz O'Connor ; Joseph R EckerSeries Type : OtherOrganism : Arabidopsis thaliana ; synthetic constructHow tissues generate asymmetric growth from spatially and temporally restricted signals remains a fundamental chall […]
- GSE319837 Niche-driven plasticity of bipotent basal epithelial cells in the human ocular surface [RNA-Seq] August 10, 2026Contributors : Yuzuru Sasamoto ; Yoshiko Fukuda ; Shinri Sato ; Kosei Suzuki ; Catherine A Lee ; Shoko Kiritoshi ; Nick Di Girolamo ; Markus H Frank ; Natasha Y Frank ; Shuoshuo Wang ; Sheethal U Nagalakshmi ; Ioannis S VlachosSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe human ocular surface comprises corneal and […]
- GSE256323 Characterizing the role of fibroadipogenic progenitor in experimental model of pancreatic cancer cachexia [RNASeq_KPC_KPCScr_and_miR-27a-KD] August 10, 2026Contributors : Ashok Narasimhan ; Lin W Tung ; Fabio Rossi ; Tara StachSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe experiment aims to understand the effect of miR-27a knockdown in pancreatic cancer cells and investigate if the knocking down miR-27a delays tumor progression.
- GSE328701 The fungal pathogen Candida auris exposes chitin to trigger IFNg and persist in hair follicles [scRNA-seq EDM_exp2] August 10, 2026Contributors : Eric D Merrill ; Victoria Prudent ; Pauline Basso ; Emilie Rapp ; Parna Moghadam ; Abram Rodriguez ; Ethan Hung ; Charlotte Hurabielle ; Jeffrey Cheng ; Raymond Cho ; Brook Abegaze ; Amanda Buck ; Kennedi Pyper ; Allessandra Veinbachs ; Elina K Wells ; Tiffany C Scharschmidt ; Michael D Rosenblum ; Ari B Molofsky ; Suzanne M NobleSeries Type : […]
- GSE342671 Longitudinal single-cell and spatial transcriptomics reveals intratumor heterogeneity, therapeutic response, and comparative value of canine marginal zone lymphoma August 10, 2026Contributors : Grace E Walker ; Marissa Macchietto ; Kelly Reid ; Lauren E Burt ; Amber Winter ; Sara Pracht ; Michelle Buettner ; Velia Penza ; Caitlin Yung ; Rose Dicovitsky ; Alana Kuzmik ; Daniel A Vallera ; Kim Demos-Davies ; Davis M Seelig ; Antonella Borgatti ; Mike Henson ; Caitlin Feiock ; Jaime F Modiano ; Shruthi Naik ; Aaron L Sarver ; Amy E Tree […]
- GSE342662 Acetate, a short-chain fatty acid, inhibits Coxiella burnetii replication via direct bacteriostatic effect and through vacuolar modulation and host cell perturbations. August 10, 2026Contributors : Dhritiman Samanta ; Yazen Germukly ; Brooke Hall ; Alexandria Quinonez SandelinSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCoxiella burnetii, the etiologic agent of Q fever, is an obligate intracellular pathogen that replicates within a specialized acidic compartment termed the Coxiella-containing vac […]
- GSE342695 Sunitinib Induces Macrophage Dysfunction and Impaired Tissue Regeneration Through Suppression of PPARγ August 10, 2026Contributors : Zhouchen Zhang ; Qiao Qiao ; Jiannan Li ; Qingxiang Li ; Yuanning Yang ; Ying Zhou ; Hongyuan HuangSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioSunitinib, a widely used multi-target tyrosine kinase inhibitor, has side effects that Q6 may impact tissue repair and regeneration, potentially contributing to […]
- GSE342674 Suppressing phosphatidylserine externalization overcomes cancer immune evasion and enhances immunotherapy August 10, 2026Contributors : Johann S Bergholz ; Grace Trombley ; Gwendolyn Cusing ; Zhaoqi Li ; Margaret E Torrence ; Geneva Sganga ; Jennifer Casey ; Shangtao Liu ; Ashley H Choi ; Samuel R Meier ; Tenzing Khendu ; Yi Yu ; Teng Teng ; Binzhang Shen ; Hannah Stowe ; Salam Shaaban ; Jannik N Andersen ; Serge GueroussovSeries Type : OtherOrganism : Homo sapiens ; Mus muscu […]
- GSE342748 EZH2 inhibitor GSK126 promotes human iPSC hematopoietic differentiation August 10, 2026Contributors : Jianyi Ding ; Andre LarochelleSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe de novo generation of human hematopoietic stem cells (HSCs) from induced pluripotent stem cells (iPSCs) represents a promising avenue for the cellular therapy of blood disorders. However, existing protocols often result in t […]
- GSE342961 Transcriptomic profiling (RNA-seq) of lung endothelial cells from wild-type (WT) and TET2KO mice following 28 days of Angiotensin II treatment. August 10, 2026Contributors : Hashum Sum ; Alison BrewerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusChronic hypertension and Angiotensin II infusion induce systemic vascular and endothelial dysfunction. To investigate cell-autonomous transcriptional changes resulting from endothelial-specific TET2 deficiency in the pulmonary micro […]
- GSE342962 Transcriptomic profiling (RNA-seq) of the mid-region heart tissue from wild-type (WT) and TET2KO mice following 28 days of Angiotensin II treatment. August 10, 2026Contributors : Hashum Sum ; Alison BrewerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusChronic Angiotensin II (Ang II) infusion is a known inducer of cardiac remodeling, hypertrophy, and fibrosis, processes that are intricately linked to endothelial dysfunction. To determine how endothelial-specific deletion of TET2 a […]
- GSE300353 Transcriptomic analysis of CAFs with silencing of TERRA lnRNA August 10, 2026Contributors : Emery Di Cicco ; Dotto Gian-PaoloSeries Type : Expression profiling by arrayOrganism : Homo sapiensThe tumor microenvironment is essential for cancer progression, yet the nuclear mechanisms that reprogram stromal fibroblasts into cancer-associated fibroblasts (CAFs) remain to be defined. Here, we identify a telomere-derived RNA–protein signali […]