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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE308165 A systematic exploration of the intrinsic mechanisms controling axon growth during development March 26, 2026Contributors : Lora Fahdan ; Oren Schuldiner ; Noa Wigoda ; Hagar MeltzerSeries Type : Expression profiling by high throughput sequencingOrganism : Drosophila melanogasterThe ability of neurons to extend axons is governed by tightly regulated genetic programs that vary across developmental stages and cell types. Understanding the molecular features that cont […]
- GSE293052 Maternal Microbiome-Derived Propionic Acid: A Key Regulator of Offspring Myelinogenesis Through Histone Lactylation-Mediated cGMP-PKG Activation March 26, 2026Contributors : Yan Zhang ; Bing Han ; Xiuqing Li ; Yan Li ; Yuan Zhang ; Xing Li ; Yan LiSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusThe maternal gut microbiome plays a crucial role in regulating offspring neurodevelopment through microbial metabolite signaling, yet its influence on central nervous sys […]
- GSE309545 Inflammatory signaling differentially changes chromatin accessibility and gene expression of the PD-associated kinase LRRK2 between human and mice March 26, 2026Contributors : Alexandra Beilina ; Jae-hyeon Park ; Natalie Landeck ; Ruth Chia ; Jinhui Ding ; Xylena Reed ; Hannah Bailey ; Changyoun Kim ; Alice Kaganovich ; Dominic Acri ; Janet Brooks ; Kareem Zaghloul ; Elise Marsan ; Raphael J Gibbs ; Alex DeCasien ; Mark R CooksonSeries Type : Genome binding/occupancy profiling by high throughput sequencing ; Express […]
- GSE309354 Inflammatory signaling differentially changes chromatin accessibility and gene expression of the PD- associated kinase LRRK2 between human and mice [multiome] March 26, 2026Contributors : Alexandra Beilina ; Jae-hyeon Park ; Natalie Landeck ; Ruth Chia ; Jinhui Ding ; Xylena Reed ; Hannah Bailey ; Changyoun Kim ; Alice Kaganovich ; Dominic Acri ; Janet Brooks ; Kareem Zaghloul ; Elise Marsan ; Raphael J Gibbs ; Alex DeCasien ; Mark R CooksonSeries Type : Expression profiling by high throughput sequencing ; Genome binding/occupa […]
- GSE316961 Transcriptomic profile of Chronic Hepatitis B patients positive for pregenomic RNA. March 26, 2026Contributors : Aikaterini Skeva ; Petros Kolovos ; Theoxaris Konstantinidis ; Maria Panopoulou ; Konstantinos MimidisSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensIn this cohort, we aimed to study the transcriptomic profile of CHB (Chronic Hepatitis B) HBeAg negative patients treated with Nucleoside Analog (NAs) and e […]
- GSE312503 Characterization of cellular responses of Ptpn6 (SHP-1) cKO in hippocampus by scRNA-seq March 26, 2026Contributors : Seung-Hye Lee ; Ainhoa Etxeberria ; Gloriia Novikova ; Monica Ge ; Brad A Friedman ; Christopher J BohlenSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPtpn6 (SHP-1) is known to impact signaling pathways in immune cells in various different ways, and in many cases, SHP1 opposes immune cell activation by […]
- GSE325617 MAF converts metabolic state into superenhancer architecture and dependency in myeloma [RPMI8226 p300 ChIP-seq] March 26, 2026Contributors : Phyllis Chong ; Julia Lim ; Wee-Joo ChngSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensLineage-specific transcription factors govern superenhancer assemblies that impose extreme transcriptional output, but how metabolic capacity sustains these regulatory hubs remains unresolved. By integrat […]
- GSE325936 Whole-genome combinatorial gene fusions generate novel genes for advanced microbial trait development March 26, 2026Contributors : Christopher R Schvarcz ; Melody M McNay ; Sabrina Baffert ; Helge ZielerSeries Type : Expression profiling by high throughput sequencingOrganism : Saccharomyces cerevisiaeTranslational fusion of two separate genes into a compound sequence encoding a fusion protein is a key evolutionary mechanism which underpins the emergence of new protein act […]
- GSE325662 Gene expression profiling of lung tissue from LPS-induced acute lung injury mice treated with Renshen Baidu Powder March 26, 2026Contributors : Fei Li ; Shixu Liu ; Peng Chen ; Guohu DiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThis dataset presents transcriptomic profiles of lung tissue from a murine model of LPS-induced acute lung injury (ALI) following treatment with Renshen Baidu Powder (RSBD). LPS induced a robust inflammatory gene sign […]
- GSE325618 Depletion of Canonical Histones Enhances Direct Reprogramming of Scavenger Cells in vivo March 26, 2026Contributors : Ismail Özcan ; Anna Reid ; Gizem Köse ; Alexander Blume ; Baris TursunSeries Type : Expression profiling by high throughput sequencingOrganism : Caenorhabditis elegansDirect reprogramming is a procedure that converts the identity of differentiated cells, which can be triggered by defined transcription factors (TFs). Cellular reprogramming offe […]
- GSE325715 Gene expression in patients with pulmonary hypertension due to valve heart disease March 26, 2026Contributors : Ana I Fernandez_Avila ; Jorge Martinez-Solano ; Javier BermejoSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo delve deeper into the molecular mechanisms underlying pulmonary hypertension secondary to left heart disease (PH-LHD), an essential step toward developing a comprehensive classification, reliab […]
- GSE325727 Dextran-coated Iron Oxide Nanoparticles impairs cardiac function in zebrafish larvae March 26, 2026Contributors : Giovanna M Oliveira ; Talita C Pereira ; Fernanda Trindade ; William Lautert-Dutra ; Maurício R Bogo ; Calum A MacRaeSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioIron Oxide Nanoparticles (IONPs) with no doubt are the next platform for theragnostic in the biomedical field. Cardiovascular pathologies take […]
- GSE325833 IL1R2 Identified as a Key Hub Gene Regulating Vascular Endothelial Function in Kawasaki Disease March 26, 2026Contributors : Xiaofeng Hong ; Qianwen Wang ; Tian Lan ; Jianxin Xu ; Yi Zhan ; Jiandong ShiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensBackground: Kawasaki disease (KD) is a multisystemic vasculitis of unknown aetiology in children. KD with coronary artery lesion is now the leading acquired heart disease in childre […]
- GSE290393 Ribosome-associated RNA of cardiac endothelial cells purified from endothelial specific RiboTag mice March 26, 2026Contributors : Haruya Kawase ; Stefan Günther ; Stefan OffermannsSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo assess the expression levels of ribosome-associated RNAs of murine cardiac endothelial cells, hearts were collected from Cdh5-CreERT2;Rpl22tm1.1Psam mice (endothelial specific RiboTag) and ribosomes of end […]
- GSE325615 MAF converts metabolic state into superenhancer architecture and dependency in myeloma [shscr ChIP-Seq] March 26, 2026Contributors : Phyllis Chong ; Julia Lim ; Wee-Joo ChngSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensLineage-specific transcription factors govern superenhancer assemblies that impose extreme transcriptional output, but how metabolic capacity sustains these regulatory hubs remains unresolved. By integrat […]