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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE225930 Early Transcriptional Responses to Human Typhoid Challenge February 22, 2026Contributors : Amber Barton ; Christoph Blohmke ; Andrew J PollardSeries Type : Expression profiling by arrayOrganism : Homo sapiensThe whole blood transcriptome 12 and 24 hours after challenge with S. Typhi Quailes Strain. Samples were collected from two studies: a dose finding study aiming to find the challenge dose giving a 60-75% attack rate, published i […]
- GSE213095 Positive feedback between cDC1s and CD8+ T cells typifies the inflammation of HLA-B27+ arthritis February 22, 2026Contributors : Fenli Shao ; Zhigui WuSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Homo sapiensEnthesitis-related arthritis (ERA) is a subtype of juvenile idiopathic arthritis (JIA) with enthesitis and sacroiliitis, which differ from other types of JIA in symptoms, pathogenesis, and outcome. Although the association of hu […]
- GSE256187 Super-enhancers reorganization controls re-sensitization of oxaliplatin-resistant FBXW7-mutated colorectal cancer [ChIP-seq] February 22, 2026Contributors : Nicolò Gualandi ; Vanessa Tolotto ; Ylenia Cortolezzis ; Eros Di GiorgioSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensEpigenetic plasticity and large-scale chromatin remodeling characterize tumor evolution and the emergence of subclones resistant to conventional therapies. Catalytically in […]
- GSE256188 Super-enhancers reorganization controls re-sensitization of oxaliplatin-resistant FBXW7-mutated colorectal cancer February 22, 2026Contributors : Vanessa Tolotto ; Nicolò Gualandi ; Ylenia Cortolezzis ; Eros Di GiorgioSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensEpigenetic plasticity and large-scale chromatin remodeling characterize tumor evolution and the emergence of subclones resistant to conventional therapies. Catalytically inactive class I […]
- GSE256465 Next Generation Sequencing Facilitates Quantitative Analysis of COL,uvr8 mutant treated with ABA or UV-B Transcriptomes February 22, 2026Contributors : Yao Peng ; Hongtao LiuSeries Type : Expression profiling by high throughput sequencingOrganism : Arabidopsis thalianaTo expore whether UV-B induce the expression of ABA-responsive genes, we compared transcriptomes of 10-d-old Col-0 and uvr8 seedlings ± 50 uM ABA treatment and 3-h exposure to 5 mol m–2 s–1 UV-B or white-light control.
- GSE319287 TPD52 Inhibits Aldosterone Synthesis Through Suppression of CAMKK2 Signaling February 22, 2026Contributors : Ling Xie ; Linqiang Ma ; Shumin Yang ; Qifu Li ; Chuan PengSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensBackground: Aldosterone-producing adenomas (APA) are a major cause of primary aldosteronism. While gene mutations in APA trigger aldosterone overproduction via Calcium signaling, their precise regula […]
- GSE319825 RNA Sequencing Study to Investigate the Role of LITAF in Regulating Gene Expression Profiles of H9C2 Cells Exposed to Hypoxia/Reoxygenation February 22, 2026Contributor : Guo YangSeries Type : Expression profiling by high throughput sequencingOrganism : Rattus norvegicusThis study employed H9C2 cells (a rat myocardial cell line) as the experimental model, with three experimental groups and four biological replicates per group, resulting in a total of 12 samples. The experimental design aimed to investigate the r […]