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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE300875 Mitochondrial toxins cause widespread downregulation of pathways in X-linked dystonia-parkinsonism patient-derived neurons April 28, 2026Contributors : Karen Grütz ; Axel Künstner ; Hauke Busch ; Christine Klein ; Philip SeiblerSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe genetic mechanism underlying the neurodegenerative movement disorder X-linked dystonia-parkinsonism (XDP) involves a retrotransposon insertion within the TAF1 gene. TAF1 encodes […]
- GSE251929 Progressive cell fate specification in morphallactic regeneration April 28, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Hydra vulgarisThis SuperSeries is composed of the SubSeries listed below.
- GSE236889 Longitudinal scRNA-seq of murine T cell transfer colitis April 28, 2026Contributors : Jennifer Fransson ; Chiara Sorini ; Eduardo J VillablancaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusIn order to describe in detail the processes involved in chronic colitis, we performed scRNA-seq at multiple time points in CD45RBhi T cell transfer colitis mouse models. These data were compared to bu […]
- GSE287338 Dynamic Reprogramming of Stromal Pdgfra-expressing cells during WNT-Mediated Transformation of the Intestinal Epithelium [Figure 2] April 28, 2026Contributors : Oscar Pellon-Cardenas ; Prateeksha Rout ; S Hassan ; E Fokas ; Ping He ; I Patel ; J Patel ; O Plotsker ; A Wu ; R Kumar ; M Akther ; Alexandra Logerfo ; S Wu ; DE Wagner ; D Boffelli ; KD Walton ; E Manieri ; Kevin Tong ; Jason R Spence ; NJ Bessman ; RA Shivdasani ; Michael P VerziSeries Type : Expression profiling by high throughput sequenc […]
- GSE263383 Unbiased niche labeling maps immune-excluded niche in bone metastasis April 28, 2026Contributors : Zhan Xu ; Fengshuo Liu ; Xiang ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMicroenvironment niches determine cellular fates of metastatic cancer cells. However, robust and unbiased approaches to identify niche components and their molecular profiles are lacking. We established Sortase A-Based Mic […]
- GSE296725 Unbiased niche labeling maps immune-excluded niche in bone metastasis April 28, 2026Contributors : Xu Zhan ; Liu Fengshuo ; Zhang XiangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMicroenvironment niches determine cellular fates of metastatic cancer cells. However, robust and unbiased approaches to identify niche components and their molecular profiles are lacking. We established Sortase A-Based Mic […]
- GSE294165 Folic acid drives metabolic reprogramming to alleviate Toxoplasma gondii antigen-induced vascular injury April 28, 2026Contributors : Jingfan Qiu ; Yingyi Quan ; Jiang Jiang ; Nan Gao ; Jing Guo ; Wei Shi ; Linfeng Jiang ; Chenlu Shao ; Yang YangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensInfection with parasites is usually accompanied by vascular problems. To investigate the detrimental effects of parasites on blood vessels. We use […]
- GSE329043 Disrupted glial-mediated synaptic refinement in Fragile X syndrome April 28, 2026Contributors : Lindsey Starr ; Melissa Lee ; Amy Vo ; Maia Weisenhaus ; Lucas Cheadle ; Archana Yadav ; Fahad Paryani ; Michelle Shirasu-Hiza ; Vilas Menon ; Carol MasonSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusFragile X syndrome (FXS), the most common inherited cause of intellectual disability and autism, results […]
- GSE328992 Beyond ACE2: DPP4 Engagement Redefines SARS-CoV-2 Receptor Tropism April 28, 2026Contributors : Yu Zhang ; Jing Li ; Yumeng Li ; Zhuangzhuang Shi ; Yunkai Zhu ; Tiecheng Wang ; Xiaoyang Zhou ; Lu Dai ; Shanshan Yang ; Ruixuan Wang ; Peng Xie ; Mengyao Yu ; Li Gao ; Jiaxin Hu ; Tao Jiang ; Lin Li ; Weiyang Sun ; Yuzhang Wu ; Liqun Fang ; Yuwei Gao ; Jintao LiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus mu […]
- GSE329270 Phosphorylated DEK sustains leukemia stem cells by enabling PBX3-driven transcriptional reprogramming [ATAC-seq 2] April 28, 2026Contributor : Zhe ChenSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensLeukemia stem cells (LSCs) drive acute myeloid leukemia (AML) initiation, relapse, and chemoresistance, yet the core post-translational events governing LSC formation and maintenance remain elusive. Here, through phosphoproteomic profili […]
- GSE329105 Vitrification of Culter alburnus Embryos by Laser-Assisted Warming with Gold Nanorods April 28, 2026Contributors : Xinqing Cai ; Yuting Luo ; Hongkuan Song ; Jiamin Wang ; Yipeng Ren ; Bingshe Han ; Junfang ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Culter alburnusCryopreservation of fish embryos is highly challenging, and to date, successful reports of fish embryo cryopreservation remain scarce. In this study, we optim […]
- GSE329274 Phosphorylated DEK sustains leukemia stem cells by enabling PBX3-driven transcriptional reprogramming [CUT&Tag 2] April 28, 2026Contributor : Zhe ChenSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensLeukemia stem cells (LSCs) drive acute myeloid leukemia (AML) initiation, relapse, and chemoresistance, yet the core post-translational events governing LSC formation and maintenance remain elusive. Here, through phosphoproteomic profili […]
- GSE329307 Ribo-seq of cavernous fibroblasts cultured on substrates with different stiffness. April 28, 2026Contributors : Biao Liu ; Yuzhuo ChenSeries Type : OtherOrganism : Homo sapiensFibrotic diseases involve increased mechanical stress due to extracellular matrix deposition, significantly altering cellular metabolism. However, a systematic understanding of how mechanical force regulates lipid metabolism across different molecular layers remains limited. We em […]
- GSE329316 Transcriptome sequencing of cavernous fibroblasts cultured on substrates with different stiffness. April 28, 2026Contributors : Biao Liu ; Yuzhuo ChenSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensFibrotic diseases involve increased mechanical stress due to extracellular matrix deposition, significantly altering cellular metabolism. However, a systematic understanding of how mechanical force regulates lipid metabolism across diff […]
- GSE300721 Progressive cell fate specification in morphallactic regeneration [RNA-seq] April 28, 2026Contributors : Clara Nuninger ; Panagiotis Papasaikas ; Sebastien Smallwood ; Jacqueline Ferralli ; Charisios TsiairisSeries Type : Expression profiling by high throughput sequencingOrganism : Hydra vulgarisThrough regeneration variable species replace lost parts of their body. This is achieved either by growth of new structures at the amputation side (epimo […]