Quick Links : Search PubMed , Finding Full Text , PubMed Advanced Search , Clinical Queries , Single Citation Matcher , FAQs & User Guide , Explore MeSH Database , Explore PubMed Journals
Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE225346 RNA-seq of the brain and spinal cord of NTDs fetal mice at day 9.5 February 8, 2026Contributors : Lu Li ; Jianting Li ; Wenbin Ren ; Zhihua CaoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo investigate the genes exprsssion change in the brain and spine at E9.5 days in the folate-deficient NTDs mouse model, we established NTDs mouse model and normal mouse model.
- GSE255505 Transcriptome changes in human PSC-derived cardiomyocytes induced by doxorubicin II February 8, 2026Contributor : Tomoya KitaniSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensDoxorubicin (DOX) is one of the most effective chemotherapeutic agents for various types of cancers. However, DOX often causes cardiotoxicity referred to as DOX-induced cardiomyopathy (DIC). In this experiment, transcriptome changes induced by do […]
- GSE255504 CRISPR screening using Human PSC-derived cardiomyocytes reveals TAOK1 as a potential therapeutic target for doxorubicin-induced cardiomyopathy I February 8, 2026Contributor : Tomoya KitaniSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensDoxorubicin (DOX) is one of the most effective chemotherapeutic agents for various types of cancers. However, DOX often causes cardiotoxicity referred to as DOX-induced cardiomyopathy (DIC). Despite extensive research aimed at identifying therape […]
- GSE275394 Global Characterization of Functional Microglia Heterogeneity in Relation to Neovascularization and Regression Phases of Oxygen-Induced Retinopathy in Mice February 8, 2026Contributor : Yuan MaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusRetinal neovascularization (RNV) is manifested in various retinal pathological conditions, often leading to irreversible blindness. Oxygen-induced Retinopathy (OIR) mouse model proves to be useful for understanding RNV. The OIR vasculatures exhibited t […]
- GSE261519 RNA-seq of sipinal cord of AR-97Q and WT mice at P7 and 13 weeks of age February 8, 2026Contributors : Tomoki Hirunagi ; Kentaro Sahashi ; Masahisa KatsunoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusAntisense oligonuleotides targeting human AR (AR-ASO) or Rest4 (Rest4-ASO) are intracerebroventriculary injected to AR-97Q mice at postnatal day 1 (P1). Gene expression profiles were analysed in the spinal […]
- GSE289213 The alterations of gene expression profiling induced by EXOSC10-AS1 knockdown in HCT116 cells. February 8, 2026Contributor : Jiaqiu LiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensLong noncoding RNAs (lncRNAs) have been identified to play increasingly important roles in tumorigenesis, and they may serve as novel biomarkers for cancer therapy. Here we report gene expression profiles of HCT116 cells treated with EXOSC10-AS1 siRN […]
- GSE286003 RNA-seq of sipinal cord of WT, AR-24Q, AR-97Q, testosterone-treated AR-97Q mice, Scramble-ASO-treated AR-97Q mice, and Rest4-ASO #3-treated AR-97Q mice at P7 February 8, 2026Contributors : Tomoki Hirunagi ; Kentaro Sahashi ; Masahisa KatsunoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTestosterone (20 mg) was subcutaneously adminstered to AR-97Q mice at postnatal day 1 (P1). Scramble-ASO and Rest4-ASO #3 were intracerebroventriculary administred to AR-97Q mice at P1.Gene expression profi […]
- GSE297754 Remodelling of the bone marrow vasculature induced by venetoclax and azacitidine damage February 8, 2026Contributors : Steven Ngo ; Dominique Bonnet ; Giuseppe A D'AgostinoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe Bcl2 inhibitor venetoclax in combination with the hypomethylating agents azacitidine (ven/aza) has become increasingly utilised clinically for the treatment of haematological malignancies. Whilst […]
- GSE289259 Integrated Transcriptomics and Metabolomics Analyses Revealed that Phenylpropanoid Metabolism Regulates the Complex Salt-alkali Tolerance in Allium mongolicum February 8, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Allium mongolicumAllium mongolicum, a xerophytic industrial plant native to the Mongolian Plateau, demonstrates notable stress resistance, though its salt-alkali tolerance mechanisms remain poorly understood. This study integrates physiological assessments, transcriptomics, metabolomi […]
- GSE310657 Quorum sensing regulator LsrR modulates resistance to oxidative stress by interfering with sulfate assimilation in avian pathogenic Escherichia coli February 8, 2026Contributors : Lanfang Kong ; Chuntian Tu ; Xiangjun Song ; Yang Wang ; Zhihao Wang ; Zhaoguo Chen ; Wenyan Fan ; Lianhua Nie ; Wei Jiang ; Xiangan HanSeries Type : Expression profiling by high throughput sequencingOrganism : Escherichia coli K-12Prokaryotes and eukaryotes endogenously generate the gaseous molecule hydrogen sulfide (H2S), which has been iden […]
- GSE306468 Single-nucleus RNA-seq results of AR-97Q and AR-24Q mice at 8 weeks of age. February 8, 2026Contributors : Tomoki Hirunagi ; Kentaro Sahashi ; Madoka Iida ; Masahisa KatsunoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo understand the early pathogenesis of motor neuron degeneration in spinal and bulbar muscular atrophy (SBMA), we conducted single-nucleus RNA-seq (snRNA-seq) on the spinal cords of AR-97Q an […]
- GSE315519 Taldo1 Knockdown impaired NADPH production in CD8+ T cells February 8, 2026Contributors : Jingyu Feng ; Qian Zhang ; Huafeng ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTransaldolase (TALDO1), is a key enzyme in the non-oxidative pentose phosphate pathway. However, the impact of Taldo1 disruption on CD8+ T cell differentiation and function remains undefined. Here, we found that knockd […]
- GSE315826 Tkt knockdown impaired NADPH production in CD8+ T cells February 8, 2026Contributors : Jingyu Feng ; Qian Zhang ; Huafeng ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTransketolase (TKT) is a key enzyme in the non-oxidative pentose phosphate pathway. However, the impact of Taldo1 disruption on CD8+ T cell differentiation and function remains undefined. Here, we found that knockdown […]
- GSE316228 A lung specific escape of intravascular metastatic breast cancer cells from cytotoxic T cell killing February 8, 2026Contributors : Marina Kizner ; Nehora Levi ; Carmel Sochen ; Julia Ryvkin ; Ofer Regev ; Alexander Zarbock ; Lea Eisenbach ; Moshe Biton ; Ronen AlonSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe lungs are a major organ of cancer metastasis. Despite advances in the usage of tumor-specific cytotoxic T cells (CTLs) w […]
- GSE318398 Mechanism of Action of Self-Assembled Nanoparticles from Cornus officinalis in Alleviating Chemotherapy-Induced Myelosuppression. February 8, 2026Contributor : Yan WangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMyelosuppression is a major side effect of chemotherapy, with a lack of ideal therapeutic approaches. In this study, self-assembled nanoparticles (PCFNPs) were prepared from Cornus officinalis. It was found that in myelosuppression models induced by c […]