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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE294193 Acetylated OsWOX13 coordinately regulated drought-responsive and NUE- related genes April 10, 2026Contributor : Mingfang TanSeries Type : Expression profiling by high throughput sequencingOrganism : Oryza sativa Japonica GroupOsWOX13 is a higher hierarchical regulator of drought resistant and NUE genes
- GSE296145 SPEN loss drives extra-follicular diffuse large B cell lymphoma with female-specific lethality and TLR pathway therapeutic vulnerabilities April 10, 2026Contributors : Benedikt Pelzer ; Matt Teater ; Cem Meydan ; Ari M MelnickSeries Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencing ; OtherOrganism : Mus musculusIn this study, we explore the interplay between SPEN and NOTCH2 truncating mutations, identifying an alternative, extra-folli […]
- GSE294391 Effect of the poly-ICLC vaccine adjuvant on prostate cancer patients’ PBMC April 10, 2026Contributors : Sujit S Nair ; Dimple Chakravarty ; Manuel Duval ; Ashutosh K TewariSeries Type : Expression profiling by arrayOrganism : Homo sapiensIdentify PBMC RNA quantities whose level might predict response to prostate HIT-IT treatmentPhase I Peripheral Blood Mononuclear Cell from 12 high risk prostate cancer patients
- GSE302740 Dehydration promotes intracellular lipid synthesis and lipid accumulation April 10, 2026Contributors : Jason Watts ; Juan Arroyo Ornelas ; Ma Wan ; Don DelkerSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusNFAT5 is transcription factor that regulates gene expression in response to hypertonic stress. Here we profile NFAT5 occupancy before and hour following hypertonic stress in mouse inner med […]
- GSE300087 Macropinocytosis inhibition attenuates pro-fibrotic responses in lung fibroblasts and pulmonary fibrosis April 10, 2026Contributors : Konstantin Tsoyi ; Ivan O Rosas ; Coarfa Cristian ; Ruiz Maria Elisa ; Waich AlanSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe conducted a single cell RNA sequencing experiment to determine the effect of a macropinocytosis inhibitor (5-(N-ethyl-N-isopropyl)-Amiloride, EIPA) in Precision Cut Lung Slic […]
- GSE293065 Spatial transcriptomic atlas of aggressive osteosarcomas reveals shared gene surface expression and immune landscape. April 10, 2026Contributors : Gaël Moquin-Beaudry ; Maria Eugénia Marques Da Costa ; Pierre Knheisser ; Corentin Thuilliez ; Baptiste Audinot ; Hanane Zair ; Nicolas Signolle ; Michael McDermott ; Marie-Dominique Tabone ; Jean-Yves Scoazec ; Birgit Geoerger ; Damien Drubay ; Nathalie Gaspar ; Antonin MarchaisSeries Type : OtherOrganism : Homo sapiensOsteosarcoma remains a […]
- GSE327108 Tet governs transcriptional programs required for intestinal stem cell development and homeostasis April 10, 2026Contributors : Niccole Auld ; Ye-Jin Park ; Yanyan Qi ; Hongjie LiSeries Type : Expression profiling by high throughput sequencingOrganism : Drosophila melanogasterFor two decades, Drosophila intestinal stem cells (ISCs) have served as a premier model for studying somatic stem cell biology. Yet, the intrinsic mechanisms driving divergent developmental trajec […]
- GSE326863 Biallelic UNC5C variants cause a recessive neurodevelopmental disorder with brain anomalies April 10, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Caenorhabditis elegansPrecise axon guidance is fundamental to neural circuit formation, yet the full spectrum of neurodevelopmental disorders arising from disruptions in this process remains undefined. Here, we describe a multi-ethnic cohort of eight patients from five independent fam […]
- GSE326714 Peripheral serotonin regulates epidermal differentiation and dermal homeostasis April 10, 2026Contributors : Matar Stéphanie ; Petit Anne-Cécile ; Mansour Nathalie ; Flipo Justine ; Gendrot Benoit ; Kanaan Peter ; Fouquet Guillemette ; Gaillard Raphaël ; Aractingi Selim ; Oules BénédicteSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSerotonin is a neurotransmitter with key peripheral functions including regula […]
- GSE326979 Benchmarking V(D)J Repertoire Reconstruction: Bulk RNA-Seq vs PCR-Based RepSeq Validated by SMRT Sequencing [RNA-Seq] April 10, 2026Contributors : Steve Genebrier ; Samuel Bastos Serra Trinca ; Ophélie Dézé ; Marie Cornic ; Maiwenn Pineau ; Karin Tarte ; Michel CognéSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe aim of this study is to benchmark methods for immunoglobulin repertoire profiling using human B-cell samples. We compare targeted VDJ […]
- GSE326977 Benchmarking V(D)J Repertoire Reconstruction: Bulk RNA-Seq vs PCR-Based RepSeq Validated by SMRT Sequencing [RACE_RepSeq] April 10, 2026Contributors : Steve Genebrier ; Samuel Bastos Serra Trinca ; Ophélie Dézé ; Marie Cornic ; Maiwenn Pineau ; Karin Tarte ; Michel CognéSeries Type : OtherOrganism : Homo sapiensThe aim of this study is to benchmark methods for immunoglobulin repertoire profiling using human B-cell samples. We compare targeted VDJ mRNA sequencing and repertoire reconstruction […]
- GSE326988 Benchmarking V(D)J Repertoire Reconstruction: Bulk RNA-Seq vs PCR-Based RepSeq Validated by SMRT Sequencing [SMRT] April 10, 2026Contributors : Steve Genebrier ; Samuel Bastos Serra Trinca ; Ophélie Dézé ; Marie Cornic ; Maiwenn Pineau ; Karin Tarte ; Michel CognéSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe aim of this study is to benchmark methods for immunoglobulin repertoire profiling using human B-cell samples. We compare targeted VDJ […]
- GSE327000 RNA-seq gene expression data for Synechococcus sp. WH8102 under continuous high, mid, and low phosphorus treatments in laboratory EFB experiments in 2025 April 10, 2026Contributors : Alba Filella ; Solange Duhamel ; Julia Diaz ; Mariona Segura-Noguera ; Adriana Gomez-Buckley ; Paul CariniSeries Type : Expression profiling by high throughput sequencingOrganism : Parasynechococcus marenigrum WH 8102Polyphosphate (polyP) is a ubiquitous and evolutionarily conserved form of phosphorus (P) present in all living organisms, yet i […]
- GSE327095 C1q and immunoglobulins mediate activity-dependent synapse loss in the adult brain. April 10, 2026Contributors : Gerard Crowley ; Minjung Kim ; Nathanael O’Neill ; Emir Turkes ; Fateme Ghasemi ; Luca Giudice ; Sebastiaan De Schepper ; Benjy J. Y. Tan ; Benito Maffei ; Laís S. S. Ferreira ; Julie Rebejac ; Javier Rueda-Carrasco ; Margarita Toneva ; John Christian Fajardo ; Judy Z. Ge ; Zhengyue Grace Yang ; Paula Korhonen ; Phillip Muckett ; Damaris Benne […]
- GSE293833 The impact of SOGA1 deficiency on gene expression in ovarian cancer cells April 10, 2026Contributor : Min LiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensSOGA1 is an autophagy-related factor that significantly influences cancer progression.Here, we identified the critical role of SOGA1 in the diagnosis and prognosis of ovarian cancer through bioinformatics analysis.Further functional experiments demonstr […]