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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE292031 Senataxin promotes recombination fidelity during antigen receptor gene diversification March 14, 2026Contributors : Alice Libri ; Jinglong Wang ; Timea Marton ; Wei Yu ; François Dossin ; Gabriel Balmus ; Bernardo Reina-San-Martin ; Richard Frock ; Chloé Lescale ; Ludovic DerianoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusImmunoglobulin (Ig) and T cell receptor (TCR) V(D)J gene recombination relies on non-homologou […]
- GSE292003 Targeted inhibition of de novo lipogenesis induces cancer cell senescence March 14, 2026Contributors : Àngela Llop-Hernández ; Sara Verdura ; Travis Van der Steen ; José Antonio Encinar ; Begoña Martin-Castillo ; George Kemble ; Elisabet Cuyàs ; Ruth Lupu ; Javier A. MenendezSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensConventional chemotherapeutic agents and radiation induce accelerated senescence in c […]
- GSE303355 Effect of WFDC21P knockdown in BT549 cells. March 14, 2026Contributors : Zean Li ; Yi Wang ; Man-Li LuoSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe identify a long noncoding RNA, WFDC21P (lnc-DC), which corelates to anti-tumor immunity in triple negative breast cancer (TNBC). To investigate the pathway that mediates the role of WFDC21P in TNBC, we knock down WFDC21P in B […]
- GSE319734 Identification of genes regulated by knockdown of HSF1 or CBFA2T2 March 14, 2026Contributors : Mitsuaki Fujimoto ; Ryosuke Takii ; Akira NakakiSeries Type : Expression profiling by arrayOrganism : Homo sapiensTo examine whether the HSF1–CBFA2T2 complex regulates gene expression in human melanoma MeWo cells, DNA microarray analysis was performed.
- GSE324320 P2X4 Drives Sex-Specific Neuroprotection in Autoimmune Neuroinflammation March 14, 2026Contributors : Paloma Mata ; Marina Bosch-Juan ; Eric Bué-Grabot ; Maria DomercqSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMicroglia critically influence multiple sclerosis (MS) pathophysiology through debris clearance, myelin repair, and modulation of neuroinflammation. These processes are partly regulated by ATP- […]
- GSE324324 A structurally dynamic chromosome 11 locus from Oryza rufipogon L. confers broad-spectrum recessive resistance to bacterial blight March 14, 2026Contributors : Zhiyuan Ji ; Shafique Muhammad SohaibSeries Type : Expression profiling by high throughput sequencingOrganism : Oryza rufipogonBacterial blight (BB), caused by Xanthomonas oryzae pv. oryzae (Xoo), is one of the most destructive diseases affecting rice production worldwide. In this study, the wild rice accession Oryza rufipogon Wild173 (UP36) e […]
- GSE324335 Multi-omics characterization of SIRT3 metabolism and its adaptation to the presence of amyloid-beta oligomers in nasal epithelial cells March 14, 2026Contributors : Paz Cartas-Cejudo ; Marina De Miguel ; Silvia Romero-Murillo ; Leire Extramiana ; Joaquín Fernández-Irigoyen ; Enrique SantamaríaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensSirtuins (SIRTs) are nicotinamide adenine dinucleotide (NAD⁺)-dependent deacetylases that regulate cellular homeostasis in a mult […]