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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE297953 bnagrp3 impaired salt tolerance May 23, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Brassica napusIn Hoagland's nutrient solution containing 200 mM NaCl, bnagrp3 exhibited slower growth and had a smaller biomass.
- GSE233462 Ubiquitin D drives colorectal cancer immune evasion and resistance to anti PD1 immunotherapy May 23, 2026Contributors : Senlin Zhao ; Jing Zhang ; Zijuan Hu ; Yushuai Mi ; Hong Zhang ; Xuefeng He ; Xinyang Zhong ; Yaxian Wang ; Ye Xu ; Sanjun Cai ; Xinxiang Li ; Ping Wei ; WanJun Chen ; Dawei LiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusUbiquitin D drives colorectal cancer immune evasion and resistance to anti PD1 imm […]
- GSE298062 scRNAseq data in limb (TA) and craniofacial (Masseter) in conditions of uninjrued and 2 and 4 days after BaCl2 injury May 23, 2026Contributors : James White ; Lauren McKaySeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe differences between regenerative programs of limb and craniofacial muscle has been suggested, yet limited molecular data exists to determine differential gene programs to drive such differences. Here, we performed scRNAseq exper […]
- GSE298034 ACC1 regulates plasma membrane cholesterol levels by controlling lipid droplet catabolism May 23, 2026Contributors : Maia Kinnebrew ; Kalani M WijesingheSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCholesterol constitutes ~30% of the lipids in the vertebrate cell plasma membrane (PM), where it plays indispensable roles in membrane trafficking and receptor signaling. Despite this, how PM cholesterol levels are sensed […]
- GSE298329 Ejaculate fraction-driven changes in porcine uterine gene expression and histological profiles May 23, 2026Contributors : Sonia Heras ; Laura Abril-Parreño ; Chiara Luongo ; Cristina Martínez-López ; Carlos Manuel Martínez-Cáceres ; Ester Párraga Ros ; Juan Seva ; Francisco Alberto García VázquezSeries Type : Expression profiling by high throughput sequencingOrganism : Sus scrofaSeminal plasma contains bioactive components capable of modulating the uterine enviro […]
- GSE298198 Molecular basis of delayed leaf senescence induced by short-term treatment with low phosphate in rice May 23, 2026Contributors : Martín-Cardoso Héctor ; Bundó Mireia ; García-Molina Antoni ; San Segundo BlancaSeries Type : Expression profiling by high throughput sequencingOrganism : Oryza sativaLeaf senescence is a programmed plant developmental process that can also be regulated by environmental factors, like nutrient availability. Although phosphorus is an essential e […]
- GSE320257 Gene expression changes after chemical knockout of ENL in RPMI 8226 cells May 23, 2026Contributors : Xin Li ; Yongcheng SongSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensENL is required for the expression of MLL1-target genes as well as the aberrant gene expression in MLL1-r leukemia. We found that the selective degradation of ENL could also lead to the death of multiple myeloma cells, and we investiga […]
- GSE303254 Induction and maturation of human Cerebroids, a unified 3D system with the full cellular diversity of the brain May 23, 2026Contributors : Huiwen Zheng ; Soumya Garawadamath ; Selin Pars ; Sean Morrison ; Kai Sempert ; Eduardo Alboroz Balmaceda ; Hannah Lesson ; Jessica Mar ; Ernst Wolvetang ; Giovanni PietrograndeSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensBrain organoids offer unprecedented opportunities to model developmental or patho […]
- GSE331260 Cordyceps sinensis extract mixture, and two active components D-Mannitol and Ergosterol associated with neuroprotective effects in H2O2-induced PC12 and SH-SY5Y cell models May 23, 2026Contributors : Yaoqiang Du ; Zeyu Lai ; Yutian Shao ; Zixue Xuan ; Liqun Hua ; Zixuan Fu ; Xiaowei Zheng ; Biqin ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiens ; Rattus norvegicusDisorders of redox homeostasis and the excessive release of hydrogen peroxide (H2O2) are pivotal events in the pathogenesis of epilepsy […]
- GSE331183 Developmental Dynamics of Blood DNA Methylation in Dairy Cattle from Birth to Adulthood: a longitudinal study based on enzymatic methyl-sequencing (EM-seq). May 23, 2026Contributors : Mohamed Oudihat ; Lotfi Bouzeraa ; Helene Martin ; Pascal Dufour ; Camila B De Lima ; Marc-André SirardSeries Type : Methylation profiling by high throughput sequencingOrganism : Bos taurusDNA methylation is a key epigenetic mechanism involved in the regulation of gene expression, development, and ageing. It is also one of the most promising b […]
- GSE331271 A nucleic acid host factor enables optimal phage replication in Escherichia coli [RILseq] May 23, 2026Contributors : Alice Collins ; Marcel Sprenger ; Josh McQuail ; Kai Papenfort ; Sivaramesh WigneshwerarajSeries Type : OtherOrganism : Escherichia coliHost acquisition by bacteriophages (phages) often entails modulation, appropriation, or inhibition of components and processes central to bacterial gene expression. Among these, small non‑coding RNAs (sRNAs) a […]
- GSE331294 Single-nucleus RNA-seq analysis of whole brains from 5xFAD mice with microglia-specific CD31 knockdown May 23, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe performed single-nucleus RNA sequencing (snRNA-seq) on whole-brain tissues from 5xFAD mice with microglia-specific CD31 knockdown to investigate transcriptional alterations associated with Alzheimer’s disease pathology. snRNA-seq analysis identified cell-type-specific t […]
- GSE331306 Microglial CD31 Orchestrates Alzheimer’s Pathology via the SHP2–STAT3–MME Axis to Restrain Aβ Clearance May 23, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMicroglia are closely linked to the pathogenesis of Alzheimer's disease (AD), yet the mechanisms by which they influence AD pathogenesis remain poorly defined. Here, we found that CD31 is predominantly expressed in microglia (rather than in neurons or astrocytes) and […]
- GSE332889 Quinolinic acid metabolism may mitigate AKI to CKD transition May 23, 2026Contributors : Marie Christelle Saade ; Amanda J Clark ; Afaf Saliba ; Samir M ParikhSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe transition from acute kidney injury (AKI) to chronic kidney disease (CKD) remains a significant clinical problem with unclear underlying mechanisms. Emerging evidence suggests that alt […]
- GSE332954 Granulocytes stimulated by Recombinant N protein (rNP) May 23, 2026Contributors : Liwei Zheng ; Minghui Li ; Weilin Gu ; Jing Zhao ; Fengmin LuSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensGranulocytes stimulated by Recombinant N protein (rNP)