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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE294836 Modular neuroinflammatory network discovery from large-scale phenotypic screening in genetically heterogeneous mice[part11] April 11, 2026Contributors : Mitchell Rezzonico ; Christopher J Bohlen ; Lisa A Miosge ; Brad A FriedmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe central nervous system represents a uniquely immune-privileged environment, with inflammatory responses involving several resident CNS-specific cell types. While stereotyped cellu […]
- GSE294926 Modular neuroinflammatory network discovery from large-scale phenotypic screening in genetically heterogeneous mice [part15] April 11, 2026Contributors : Mitchell Rezzonico ; Christopher J Bohlen ; Lisa A Miosge ; Brad A FriedmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe central nervous system represents a uniquely immune-privileged environment, with inflammatory responses involving several resident CNS-specific cell types. While stereotyped cellu […]
- GSE294849 Modular neuroinflammatory network discovery from large-scale phenotypic screening in genetically heterogeneous mice [part13] April 11, 2026Contributors : Mitchell Rezzonico ; Christopher J Bohlen ; Lisa A Miosge ; Brad A FriedmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe central nervous system represents a uniquely immune-privileged environment, with inflammatory responses involving several resident CNS-specific cell types. While stereotyped cellu […]
- GSE327123 Genome-Wide Dual-Selection Unveils Novel Self-Cleaving Ribozymes in the Human Genome April 11, 2026Contributors : Zhe Zhang ; Jian Zhan ; Yaoqi ZhouSeries Type : OtherOrganism : Homo sapiensThe landscape of catalytic RNAs in complex eukaryotes remains poorly charted. Although self-cleaving ribozymes are widespread in microbial and viral genomes, their existence and functional roles in humans remain largely unknown. Here, we introduce a generalizable, geno […]
- GSE294958 Modular neuroinflammatory network discovery from large-scale phenotypic screening in genetically heterogeneous mice [part17] April 11, 2026Contributors : Mitchell Rezzonico ; Christopher J Bohlen ; Lisa A Miosge ; Brad A FriedmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe central nervous system represents a uniquely immune-privileged environment, with inflammatory responses involving several resident CNS-specific cell types. While stereotyped cellu […]
- GSE294535 Modular neuroinflammatory network discovery from large-scale phenotypic screening in genetically heterogeneous mice[part5] April 11, 2026Contributors : Mitchell Rezzonico ; Christopher J Bohlen ; Lisa A Miosge ; Brad A FriedmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe central nervous system represents a uniquely immune-privileged environment, with inflammatory responses involving several resident CNS-specific cell types. While stereotyped cellu […]
- GSE294402 Modular neuroinflammatory network discovery from large-scale phenotypic screening in genetically heterogeneous mice [part1] April 11, 2026Contributors : Mitchell Rezzonico ; Christopher J Bohlen ; Lisa A Miosge ; Brad A FriedmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe central nervous system represents a uniquely immune-privileged environment, with inflammatory responses involving several resident CNS-specific cell types. While stereotyped cellu […]
- GSE325885 Polymicrobial extracellular vesicles reduce the innate immune response of human cystic fibrosis bronchial epithelial cells April 11, 2026Contributors : Lily A Charpentier ; Bruce A StantonSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensAdults with cystic fibrosis (CF) have chronic antibiotic-resistant polymicrobial lung infections, the leading cause of death in CF. We developed a polymicrobial culture model containing four genera that represents a ‘pulmo […]
- GSE310878 Molecular phenotyping of diverse human skeletal muscles with CAGE-Seq April 11, 2026Contributors : Andrey I Buyan ; Ivan V Kulakovskiy ; Oleg A Gusev ; Guzel R Gazizova ; Elena I Shagimardanova ; Yulia P Sergeeva ; Leyla ShigapovaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensDifferent skeletal muscles have distinct gene expression profiles, yet, in humans, the skeletal muscle transcriptome has been e […]
- GSE327031 Gene expression in whole seedlings (wild-type, nlp6nlp7-KO) April 11, 2026Contributors : Yasuhito Sakuraba ; Shuichi YanagisawaSeries Type : Expression profiling by arrayOrganism : Arabidopsis thalianaTo examine differential effect of the mutation of Arabidopsis NLP6 and NLP7 on the gene expressions, we performed microarray analysis using root tissue of seedlings of wild-type and nlp6nlp7 double mutant.
- GSE325886 Polymicrobial extracellular vesicles reduce the innate immune response of human cystic fibrosis bronchial epithelial cells April 11, 2026Contributors : Lily A Charpentier ; Bruce A StantonSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Prevotella melaninogenica ATCC 25845 ; Pseudomonas aeruginosa PA14 ; Staphylococcus aureus subsp. aureus str. Newman ; Streptococcus sanguinis SK36Adults with cystic fibrosis (CF) have chronic antibiotic-resistant polymicrobial lu […]
- GSE327044 Lenvatinib exacerbates colitis by inhibiting intestinal vascular endothelial MAdCAM-1-mediated B cell trafficking April 11, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe use of lenvatinib (Lenv) in advanced hepatocellular carcinoma (HCC) patients is associated with a range of adverse events, including gastrointestinal toxicities, yet the underlying mechanisms remain poorly understood. Here, we demonstrated that Lenv exacerbated both ac […]
- GSE327105 Lenvatinib exacerbates colitis by inhibiting intestinal vascular endothelial MAdCAM-1-mediated B cell trafficking. April 11, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe use of lenvatinib (Lenv) in advanced hepatocellular carcinoma (HCC) patients is associated with a range of adverse events, including gastrointestinal toxicities, yet the underlying mechanisms remain poorly understood. Here, we demonstrated that Lenv exacerbated both ac […]
- GSE327117 Transcriptomic and Accessibilty characterization of Wild type mouse Embryonic Stem Cells (mESCs), β-actin Knock out mESC and upon rescue with a nuclear localization signal β-actin April 11, 2026Contributors : Nadine Hosny El Said ; Colin Campbell ; Amani Nuairi ; Sabrina Desbordes ; Piergiorgio PercipalleSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusPluripotency and lineage commitment in embryonic stem cells depend on coordinated regulation of chromatin architecture and extracellular matrix (EC […]
- GSE294826 Modular neuroinflammatory network discovery from large-scale phenotypic screening in genetically heterogeneous mice [part9] April 11, 2026Contributors : Mitchell Rezzonico ; Christopher J Bohlen ; Lisa A Miosge ; Brad A FriedmanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe central nervous system represents a uniquely immune-privileged environment, with inflammatory responses involving several resident CNS-specific cell types. While stereotyped cellu […]