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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE307672 Cancer Stem Cells Induce Proline Synthesis through FAM3C-Mediated SPIN1 Stabilization to Attenuate ROS Stress March 22, 2026Contributors : Weichi Wu ; Donghai Wang ; Jeremy RichSeries Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensTumors reprogram amino acid metabolism to dysregulate cellular growth through multiple mechanisms. Here, we find that glioblastoma (GBM) stem cells (GSCs […]
- GSE261051 Pheno-transcriptomic characterization of hooked hairs in common bean March 22, 2026Contributors : Sergio A Cervantes-Perez ; Ankita Roy ; Peter Piertzyk ; Sandra Thibivilliers ; Marc Libault ; Alexander BuckschSeries Type : Expression profiling by high throughput sequencingOrganism : Phaseolus vulgarisThe environmental changes caused by climate change enhance the effects of land degradation. This faces a big challenge for agriculture to se […]
- GSE308560 Plasma Olink Explore HT of primary glomerular disease patients March 22, 2026Contributors : Jae-ik Oh ; Kyeonghun Jeong ; Jung Hun Koh ; Jin Gyeong Kwon ; Semin Cho ; Jeong Min Cho ; Yaerim Kim ; Hajeong Lee ; Hyun Je Kim ; Jeonghwan Lee ; Jung Pyo Lee ; Ji In Park ; Jung Tak Park ; Kwangsoo Kim ; Sehoon Park ; Dong Ki KimSeries Type : OtherOrganism : Homo sapiensThis study utilized large-scale systemic proteome profiling to identify […]
- GSE308380 Gene expression in Meckel's and condylar cartilages from WT and FGFR3 mutant mice March 22, 2026Contributors : Martin Biosse Duplan ; Valentin Estibals ; Mohammed Zarhrate ; Laurence Legeai MalletSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMeckel's and condylar cartilages are key to mandible development. In achondroplasia, the most common form of genetic dwarfism, abnormalities of these cartilages lead to […]
- GSE315168 Sprayable Nanozyme Hydrogel Epigenetically Reprograms Inflammation for Diabetic Wound Regeneration [mRNA-seq] March 22, 2026Contributors : Amal George Kurian ; Jeong-Hui Park ; Shanika Karunasagara ; Archita Gupta ; Shreyas Kumar Jain ; Tanza Baby ; Ueon Sang Shin ; Sak Lee ; Rajendra K Singh ; Jung-Hwan Lee ; Kam W Leong ; Hae-Won KimSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusChronic diabetic wounds present a critical clinical challeng […]
- GSE315167 Sprayable Nanozyme Hydrogel Epigenetically Reprograms Inflammation for Diabetic Wound Regeneration [ATAC-seq] March 22, 2026Contributors : Amal George Kurian ; Jeong-Hui Park ; Shanika Karunasagara ; Archita Gupta ; Shreyas Kumar Jain ; Tanza Baby ; Ueon Sang Shin ; Sak Lee ; Rajendra K Singh ; Jung-Hwan Lee ; Kam W Leong ; Hae-Won KimSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusChronic diabetic wounds present a critical cli […]
- GSE319127 Sprayable Nanozyme Hydrogel Epigenetically Reprograms Inflammation for Diabetic Wound Regeneration [GeoMX spatial transcriptomics] March 22, 2026Contributors : Amal George Kurian ; Jeong-Hui Park ; Shanika Karunasagara ; Archita Gupta ; Shreyas Kumar Jain ; Tanza Baby ; Ueon Sang Shin ; Sak Lee ; Rajendra K Singh ; Jung-Hwan Lee ; Kam W Leong ; Hae-Won KimSeries Type : OtherOrganism : Rattus norvegicusChronic diabetic wounds present a critical clinical challenge due to persistent inflammation and com […]
- GSE317333 Single-cell transcriptomic profiling of NRasG12V/myrAKT-driven hepatocellular carcinoma with Sepp1 knockdown and selenium supplementation March 22, 2026Contributors : Jiazheng Jiao ; Lixing ZhanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe immune microenvironment of hepatocellular carcinoma (HCC) is strongly influenced by tumor-infiltrating neutrophils, whose functional heterogeneity and regulatory mechanisms remain incompletely defined. Selenium metabolism, medi […]
- GSE324084 Transcriptomic analyses of human islets March 22, 2026Contributors : G Pasquetti ; J Kerr-Conte ; F Pattou ; J Vandel ; C Amayene AmassogoSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiens58 human clinical islet preparations were selected from the frozen biobank of the Cell Therapy Unit of Lille University Hospital. Total RNA was extracted and subjected to high-throughput se […]
- GSE320430 Sprayable Nanozyme Hydrogel Epigenetically Reprograms Inflammation for Diabetic Wound Regeneration [Chip-seq] March 22, 2026Contributors : Amal George Kurian ; Jeong-Hui Park ; Shanika Karunasagara ; Archita Gupta ; Shreyas Kumar Jain ; Tanza Baby ; Ueon Sang Shin ; Sak Lee ; Buuvee Bayarkhangai ; Rajendra K Singh ; Jung-Hwan Lee ; Kam W Leong ; Hae-Won KimSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusChronic diabetic wounds […]
- GSE325026 Defining Chicken Host Responses to Spotty Liver Disease March 22, 2026Contributors : Varsha Bommineni ; Lekshmi K Edison ; Chaitanya Gottapu ; Gary D Butcher ; Subhashinie KariyawasamSeries Type : Expression profiling by high throughput sequencingOrganism : Gallus gallusSpotty Liver Disease (SLD) is an acute bacterial infection of layer hens, caused by Campylobacter hepaticus, and occurs most frequently in barn-housed and free […]
- GSE325124 Single-cell transcriptomic analysis of hepatic immune cells from untreated and ConA-treated mice March 22, 2026Contributors : Wenyu Tian ; Weixuan Wang ; Dan LvSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusHepatic immune tolerance is essential for maintaining liver homeostasis, but its underlying cellular and molecular mechanisms remain poorly defined. In this study, we established a low-dose concanavalin A (ConA)-induced immu […]
- GSE325144 Targeted DNA methylation editing in vivo [mouse brain] March 22, 2026Contributors : Maria Kalomoiri ; Chiara Sorini ; Sebastiaan Vos ; Anderson Camargo ; Chandana Rao Prakash ; Per Svenningsson ; Majid Pahlevan Kakhki ; Lara Kular ; Maja JagodicSeries Type : Methylation profiling by arrayOrganism : Mus musculusThe number of epigenome-wide association studies linking CpG DNA methylation with disease, traits and exposures, cont […]
- GSE325146 Targeted DNA methylation editing in vivo [mouse spleen] March 22, 2026Contributors : Maria Kalomoiri ; Chiara Sorini ; Sebastiaan Vos ; Anderson Camargo ; Chandana Rao Prakash ; Per Svenningsson ; Majid Pahlevan Kakhki ; Lara Kular ; Maja JagodicSeries Type : Methylation profiling by arrayOrganism : Mus musculus ; Trametes gibbosaThe number of epigenome-wide association studies linking CpG DNA methylation with disease, traits […]
- GSE325169 Correcting the immune microenvironment disturbed by the overactivation of the neutrophil-driven microglia positive feedback loop efficiently suppressed pathological retinal angiogenesis March 22, 2026Contributors : Ziyi Zhou ; Tianhao Yuan ; Guorui DouSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusDisrupting Galectin-3/NET-mediated microglia-neutrophil crosstalk suppresses retinal angiogenesis, revealing self-reinforcing immune mechanisms in advanced disease.