Category: pubmed

NCBI Insights

• Changes Coming to NCBI Taxonomy: Try the New Browser March 11, 2026
  We invite you to try the redesigned NCBI Taxonomy Browser, developed with input from our user community. In Summer 2026, the legacy Taxonomy Browser will redirect to the new browser in NCBI Datasets. We will fully transition to the new browser in Fall 2026. Legacy FTP and E-utilities access will remain available for existing programmatic workflows, but we en […]
  NCBI Staff
• MANE v1.5 Released! March 10, 2026
  A new version (v1.5) of Matched Annotation from NCBI and EMBL-EBI (MANE) is now available. This dataset, produced in collaboration between NCBI and the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), includes a total of 19,437 MANE Select transcripts for 19,367 protein-coding and 70 non-coding genes. There are also MANE […]
  NCBI Staff
• GenBank Release 270.0 March 5, 2026
  GenBank release 270.0 (2/18/2026) is now available on the NCBI FTP site. This release has 51.56 trillion bases and 6.12 billion records.  The current release has:   260,943,419 traditional records containing 7,010,340,901,567 base pairs of sequence data  4,620,211,924 WGS records containing 43,580,847,616,334 base pairs of sequence data  1,046,996,602 bulk-o […]
  NCBI Staff
• Now Live: Genetic Testing Registry (GTR®) Search Improvements March 4, 2026
  With a new tool to compare clinical genetic tests!  NCBI is pleased to announce an improved search and navigation experience in the NIH Genetic Testing Registry (GTR®). We previously highlighted a number of updates during the Beta phase of implementation— thank you for your feedback during this time. All updates are now live in GTR!  What’s new?  One search […]
  NCBI Staff
• Update to ClinVar’s Submission API March 2, 2026
  Enhancing Functional Data Submission   The ClinVar team is excited to announce updates to the ClinVar Submission API for improved representation of functional data. A previous blog post described these improvements for functional data in file submissions, downloadable FTP files, and our website.   What’s new?  The Submission API schema has been updated! If y […]
  NCBI Staff
• Now Available: RefSeq Release 233 February 19, 2026
  RefSeq release 233 is now available online and from the FTP site! You can access RefSeq data through NCBI Datasets. The release is provided in several directories as a complete dataset and also as divided by logical groupings.    What’s included in this release?  As of January 26, 2026, this full release incorporates genomic, transcript, and protein data con […]
  NCBI Staff
• Changes to PMC Article Dataset Distribution Services Coming in 2026 February 12, 2026
  PMC will make major changes to our Article Dataset Distribution Services in 2026. In August 2026, you will need to access full text article data files through the PMC Cloud Service instead of the PMC FTP Service. This change will provide you with more reliable performance, faster retrieval times, and greater flexibility in retrieving only the types and numbe […]
  NCBI Staff
• Now Available! NCBI Hidden Markov Models (HMM) Release 19.0 February 11, 2026
  Download release 19.0 of the NCBI protein profile Hidden Markov models (HMMs) used by the Prokaryotic Genome Annotation Pipeline (PGAP). You can search this collection against your favorite prokaryotic proteins to identify their function using the HMMER sequence analysis package.   What’s new?   Release 19.0 contains:   18,513 HMMs maintained by NCBI   465 n […]
  NCBI Staff
• NCBI Celebrates International Love Data Week! February 10, 2026
  Providing free and open access to scientific literature and data   Do you love biomolecular data as much as we do? Join NCBI in celebrating International Love Data Week, February 9-13, 2026! Love Data Week is an international celebration of data, which takes place every year during the week of Valentine’s Day. This year’s theme is “Where’s the Data?” and enc […]
  NCBI Staff
• BankIt Submitters: Upcoming Changes to How You Submit to GenBank January 27, 2026
  Are you a GenBank submitter? Do you use BankIt or the GenBank app in the NCBI Submission Portal to submit your sequences? Or do you split your data between the two systems?    Starting this spring, you will be able to complete all GenBank submissions in the portal! The Submission Portal GenBank will support data types that you currently submit through BankIt […]
  NCBI Staff