Category: pubmed

Gene Expression Omnibus Announcements & Study Releases

Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.

• GSE236514 Mouse lncRNA profiling cardiac tissue July 4, 2026
  Contributor : Leon de WindtSeries Type : Expression profiling by array ; Non-coding RNA profiling by arrayOrganism : Mus musculusmouse lncRNA profiling cardiac tissuelncRNA/mRNA experssion profiling
• GSE336959 RNA-seq profiling of spinal cord tissues from SCI and ovariectomy-associated osteoporotic SCI mouse models July 4, 2026
  Contributors : Zhou Quan ; Zhou QuanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBulk RNA-seq was performed on 12 female 8-week-old C57BL/6J wild-type mouse spinal cord samples to compare transcriptomic changes among SCI7, OVX2_SCI7, and OVX8_SCI7 groups. SCI7 samples were collected 7 days after T9-T10 clip-compressi […]
• GSE272949 tRNA m1A modification promotes benign prostatic hyperplasia through translational regulation of the TGF-β pathway [Ribo-seq] July 4, 2026
  Contributors : Yuhan Liu ; Libo Yu ; Xinhui Liao ; Ru HuangSeries Type : OtherOrganism : Homo sapiensBenign prostatic hyperplasia (BPH) is a common urological disease affecting elderly men. Although global hypermethylation has been implicated in BPH pathogenesis, the specific role of N1-methyladenosine (m1A) tRNA modifications remains unclear. Here, we find […]
• GSE236737 CircularRNAs (circRNAs) sequencing in hepatocellular carcinoma (HCC) patients with and without microvascular invasion (MVI) July 4, 2026
  Contributors : Xin Hu ; Ronggao Chen ; Guanrong Chen ; Xiao XuSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensFormed by cis back-splicing and circularization of introns, exons and other transcripts, circRNAs constitute covalently closed single-stranded loops and are considered as the emerging non-coding RNAs. Accumu […]
• GSE301714 Mezigdomide reverses T cell exhaustion through degradation of Aiolos/Ikaros and reinvigoration of cytokine production pathways [scATAC-seq] July 4, 2026
  Contributors : Junfei Zhao ; Hsiling Chiu ; Patrick HagnerSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensGiven the well-established notion that T cells undergo significant changes in their nuclear architecture and chromatin accessibility between different stages of differentiation or phenotypic stage such […]
• GSE272951 tRNA m1A modification promotes benign prostatic hyperplasia through translational regulation of the TGF-β pathway [tRNA-seq] July 4, 2026
  Contributors : Yuhan Liu ; Libo Yu ; Xinhui Liao ; Ru HuangSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensBenign prostatic hyperplasia (BPH) is a common urological disease affecting elderly men. Although global hypermethylation has been implicated in BPH pathogenesis, the specific role of N1-methyladenosine (m1A) t […]
• GSE302227 Murine model of MRSA-induced kidney injury (Multiome) July 4, 2026
  Contributor : Hato TakashiSeries Type : Genome binding/occupancy profiling by high throughput sequencing ; Expression profiling by high throughput sequencingOrganism : Mus musculusMultiome RNA sequencing was performed on mouse kidneys 5 days after systemic MRSA infection. For each sample, kidneys from two individual mice were pooled.
• GSE301716 Mezigdomide reverses T cell exhaustion through degradation of Aiolos/Ikaros and reinvigoration of cytokine production pathways [RNA-seq] July 4, 2026
  Contributors : Junfei Zhao ; Hsiling Chiu ; Patrick HagnerSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensGiven the well-established notion that T cells undergo significant changes in their nuclear architecture and chromatin accessibility between different stages of differentiation or phenotypic stage such as activation […]
• GSE329527 Antigen-restricted homeostatic Candida albicans Th17 cells link oral-gut immunity and adapt in intestinal inflammation July 4, 2026
  Contributors : Gabriela Rios Martini ; Philipp Hofmann ; Ann K Kamps ; Amos Weichberger ; Ekaterina Tikhonova ; Aidan Conroy ; Xiangyu Pan ; Diana M Namuch ; Laura Rathjens ; Arne Bergfeld ; Susanna Nikolaus ; Jeanette Riffert ; Florian Tran ; Konrad Aden ; Maria Witte ; Clemens Schafmayer ; Dora Stölzl ; Stephan Weidinger ; Markus M Heimesaat ; Miriam Cyris […]
• GSE313792 Curtailment of Toll-like receptor signalling and cytokine production in dendritic cells by secreted products of Heligmosomoides polygyrus July 4, 2026
  Contributors : Andrea M Kemter ; Alasdair C Ivens ; Rick M MaizelsSeries Type : Expression profiling by arrayOrganism : Mus musculusDendritic cells (DCs) are the professional antigen-presenting cells responsible for recognition of pathogens and induction of appropriate adaptive immune responses. Many successful pathogens have evolved to release molecular pro […]
• GSE336332 Effects of GLUT3 on transcription and translation in aged primary HUVECs July 4, 2026
  Contributor : Wanzhou WuSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Homo sapiensYoung HUVECs were infected with lentivirus to overexpress GLUT3, and a replicative senescence cell model was established through replicative passaging. Subsequently, mRNA-seq and Ribo-seq were performed on young HUVECs, replicatively senesce […]
• GSE336907 Soft matrix promotes ciliogenesis in human retinal pigment epithelial cells July 4, 2026
  Contributors : Rida Zahra ; Natalie Munding ; Katrin Domsch ; Hannah Braun-Lee ; Camila García-Navarrete ; Motomu Tanaka ; Gislene PereiraSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe primary cilium (PC) is a microtubule-based mechanosensory organelle involved in signal transduction. Although the signaling functio […]
• GSE336950 Epstein-Barr Virus Induced B cell Methionine Dependency is a Targetable Metabolic Vulnerability July 4, 2026
  Contributors : Rui Guo ; Shaowen White ; Bidisha Mitra ; Hanqi Li ; Rishi Puri ; John M Asara ; Benjamin E GewurzSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensEBV uses latency III oncoproteins to drive abnormal B cell proliferation to establish lifelong latency, and oncoprotein+ B cells correlate to pathology in autoi […]
• GSE301718 Mezigdomide reverses T cell exhaustion through degradation of Aiolos/Ikaros and reinvigoration of cytokine production pathways [Hi-C] July 4, 2026
  Contributors : Junfei Zhao ; Hsiling Chiu ; Patrick HagnerSeries Type : OtherOrganism : Homo sapiensGiven the well-established notion that T cells undergo significant changes in their nuclear architecture and chromatin accessibility between different stages of differentiation or phenotypic stage such as activation and exhaustion, we aimed to investigate the […]
• GSE302226 Mouse kidney Methicillin-resistant Staphylococcus aureus infection time course July 4, 2026
  Contributor : Hato TakashiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBulk kidney RNA sequencing was performed on mouse kidneys after systemic MRSA infection. C57BL/6 male mice were injected via the tail vein with 5 x 10^7 CFU MRSA (USA300 JE2), and kidney tissues were harvested at days 0 (control), 1, 2, 3, 4, 7, 9 […]