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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE240587 Changes in gene expression after astrocytes PTBP1 knockdown August 9, 2026Contributors : Liu Yan ; Wenlong Zhang ; Yunlong ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo test how Ptbp1 knockdown in vitro, we employed RNA-seq analysis.
- GSE274929 RNA-seq of bone marrow-derived macrophages(BMDMs) coclutured with mEC25 cancer cell lines August 9, 2026Contributors : Kun Chen ; Peng wang ; Zhengfei ZhuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusOur findings revealed that when BMDMs cocultured with cancer cell lines in contact, auch as mEC25,their SIRPαexpression would upregulated compared with their coculture in a non-contact manner.To investigate the underlying m […]
- GSE274441 RNA-seq for CMK and M07E cell line in either the absence or presence of GNE987 August 9, 2026Contributors : Fang Fang ; Jian Pan ; Ailian Guo ; Zhiheng LiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensNext-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare RNA-seq results for CMK and M07E cell line in either the absence or presence […]
- GSE304561 Heterogeneity in B- and epithelial-cell senescence in the pathogenesis of COPD/emphysema [scRNA-seq] August 9, 2026Contributors : Gagandeep Kaur ; Qixin Wang ; Felix Effah ; Sadiya Bi Shaikh ; Calla Fahey ; Ariel Tjitropronoto ; Hoshang Unwalla ; Manoj Mammen ; Irfan RahmanSeries Type : Other ; Expression profiling by high throughput sequencingOrganism : Homo sapiensIncreased cellular senescence leading to premature lung aging is a key mechanism for chronic inflammation […]
- GSE275198 Exploring transcriptomic change in CM-Leukemia August 9, 2026Contributors : Lianjun Zhang ; Yu-Hsuan Fu ; Ya-Huei KuoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo explore the transcriptome change in CM-leukemia, we performed RNA-seq for bone marrow mononuclear cells from CM mice at the leukemic stage and control littermate.
- GSE310162 Heterogeneity in B- and epithelial-cell senescence in the pathogenesis of COPD/emphysema [Xenium] August 9, 2026Contributors : Gagandeep Kaur ; Qixin Wang ; Felix Effah ; Sadiya Bi Shaikh ; Calla Fahey ; Ariel Tjitropronoto ; Hoshang Unwalla ; Manoj Mammen ; Irfan RahmanSeries Type : OtherOrganism : Homo sapiensIncreased cellular senescence leading to premature lung aging is a key mechanism for chronic inflammation and airway remodeling in emphysematous-COPD. However, […]
- GSE304798 Heterologous expression of the C-terminus of voltage gated sodium channel Nav1.2 in neuroblastoma N1E115 cells August 9, 2026Contributors : Julio C Luna-Rojas ; Luis M Arratia-Cortés ; Erik A Romero-Macias ; Ana V VegaSeries Type : Expression profiling by arrayOrganism : Mus musculusTranscriptional profile in neuroblastoma cells expressing a fusion protein between green fluorescent protein(EGFP) and amino acids 1778 to 2006 of mouse voltage-gated sodium channel alpha subunit NaV1. […]
- GSE326810 OsIDD7 integrates signaling networks for arbuscular mycorrhizal symbiosis August 9, 2026Contributors : Man-Chi Ho ; Shu-Yi YangSeries Type : Expression profiling by high throughput sequencingOrganism : Oryza sativaArbuscular mycorrhizal (AM) symbiosis is an ancient and widespread mutualism between plant roots and Glomeromycotina fungi that enables nutrient exchange through arbuscules. Here, we identify the rice INDETERMINATE DOMAIN (IDD) transc […]
- GSE324312 Chronoregulation of innate immune cell fibrinolytic activity August 9, 2026Contributors : Paula A Klavina ; Roger J Preston ; Annie M CurtisSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPeritoneal macrophages are important for pathogen clearance, forming cell-pathogen aggregates held together by fibrin. This can be beneficial in limiting the spread of pathogens, however, persistent fibrin de […]
- GSE327762 OsIDD7 integrates signaling networks for arbuscular mycorrhizal symbiosis [DAP-seq] August 9, 2026Contributors : Wan-Ning Kuo ; Yu-Ting Chang ; Pei-Jung Chen ; Shu-Yi YangSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Oryza sativaArbuscular mycorrhizal (AM) symbiosis is an ancient and widespread mutualism between plant roots and Glomeromycotina fungi that enables nutrient exchange through arbuscules. Here, we ide […]
- GSE342353 A Nanomolar-Affinity Antibody Enabling Sensitive Labeling and High-Resolution Genomic Mapping of O-GlcNAc August 9, 2026Contributors : Weiyao Hong ; Che Zhang ; Xiaoyang GuoSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusHigh-affinity O-GlcNAc-specific antibodies are crucial for the sensitive detection and functional study of O‑GlcNAcylation. Here, we report the development of a pan-specific, nanomolar-affinity O-GlcNAc ant […]
- GSE342412 Global regulatory role of stringent starvation protein SspA in modulating IncX3 plasmid fitness cost in Escherichia coli August 9, 2026Contributors : Ziyi Liu ; Ying Tang ; Chenggang XuSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Escherichia coliThe IncX3 plasmid is a primary vector for disseminating carbapenem resistance globally, yet the chromosomal regulatory mechanisms governing its fitness cost remain poorly understood. Our previous work iden […]
- GSE342585 LCK deficiency in CD8 T cells leads to reduced proliferation and increased effector T-cell formation in mice [Bulk RNA-seq] August 9, 2026Contributors : Valeria Uleri ; Veronika Niederlova ; Juraj Michalik ; Ondrej StepanekSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusLCK is an SRC-family kinase that mediates the initial steps in T-cell antigen receptor signaling and governs positive and negative selection during thymocyte development. While its develop […]
- GSE342586 LCK deficiency in CD8 T cells leads to reduced proliferation and increased effector T-cell formation in mice [scRNA-seq] August 9, 2026Contributors : Valeria Uleri ; Veronika Niederlova ; Juraj Michalik ; Ondrej StepanekSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Mus musculusLCK is an SRC-family kinase that mediates the initial steps in T-cell antigen receptor signaling and governs positive and negative selection during thymocyte development. While its […]