Quick Links : Search PubMed , Finding Full Text , PubMed Advanced Search , Clinical Queries , Single Citation Matcher , FAQs & User Guide , Explore MeSH Database , Explore PubMed Journals
Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE295696 ATAC-seq to Profile the Chromatin Accessibility in RBM22-silencing and Control Primary Cardiomyocytes February 12, 2026Contributors : Zhenzhen Zhan ; Xingguang Liu ; Xuewen DuanSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusPurpose: The purpose of this study is to identify chromatin alterations regulated by RBM22. We performed ATAC-sequencing in primary cultured neonatal mouse cardiomyocytes transfected with control siRNA […]
- GSE295695 Next Generation Sequencing Facilitates Quantitative Analysis of RBM22-silencing and Control Primary Neonatal Mouse Cardiomyocytes Transcriptomes February 12, 2026Contributors : Zhenzhen Zhan ; Xingguang Liu ; Xuewen DuanSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPurpose:The purpose of this study is to identify genes that are either activated or silenced in cardiomyocytes treated with siRNA targeting RBM22 (si-Rbm22) compared to control siRNA (si-Control). Gene expression di […]
- GSE311241 ATAC-seq Profiling of Adult Mouse Cardiomyocytes Treated with AAV9-cTnT-Rbm22 in MI Model February 12, 2026Contributors : Zhenzhen Zhan ; Xingguang Liu ; Xuewen DuanSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusPurpose: The purpose of this study was to identify chromatin alterations regulated by RBM22 in adult mouse cardiomyocytes (AMCMs) after myocardial infarction (MI). We performed ATAC sequencing on AMCMs […]
- GSE295697 RBM22 CUT&Tag Profiling of Regenerative (P1) and Non-Regenerative (P8) Neonatal Mouse Cardiomyocytes February 12, 2026Contributors : Zhenzhen Zhan ; Xingguang Liu ; Xuewen DuanSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusPurpose: To uncover the molecular mechanisms underlying RBM22-mediated neonatal heart regeneration, we performed Cleavage Under Targets and Tagmentation (CUT&Tag) analysis on regenerative and non-r […]
- GSE189768 A Dominant mutation in Dnmt1 leads epigenetic changes (RNA-BS-seq) February 12, 2026Contributor : Jing WangSeries Type : Methylation profiling by high throughput sequencingOrganism : Mus musculusWe report the application of rnaseq on the Dnmt1 A560V mice
- GSE319044 Single-cell multiomic profiling of lung immune cells identifies novel asthma risk genes and cell-type specific functions February 12, 2026Contributors : Jing Gu ; Donna C Decker ; Xiaoyuan Zhong ; Anne I Sperling ; Carole Ober ; Marcelo A Nóbrega ; Xin He ; Nathan SchoettlerSeries Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensGenetic variants associated with asthma are mostly in non-coding regi […]
- GSE317982 Fragmentation through cell-cell adhesion maintains senescent cell viability but promotes debris deposition February 12, 2026Contributors : Matej Durik ; William M KeyesSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe identified that senescent cells dispose of large fragments of themselves through cell-to-cell adhesion, which we term senescent-cell adhesion fragments (SCAFs). Dynamic analyses show that SCAFs ultimately rupture, releasing a […]
- GSE289419 Evaluating the Suitability of the Rat Footshock Model for Studying Gut-Brain Interactions and IBS-Related Gene Expression in PTSD Research February 12, 2026Contributors : Fazia Ait Zenati ; Leandro Di Gloria ; Matteo RamazzottiSeries Type : OtherOrganism : Rattus norvegicusPost-traumatic stress disorder (PTSD) is a mental health condition that has been associated with changes in gut microbiota and intestinal function. However, the molecular mechanisms driving these changes are not fully understood, and there is […]
- GSE318842 Hap complex regulates the development of Penicillium oxalicum fungi and the expression of cellulolytic genes February 12, 2026Contributors : Kexuan Ma ; Yuqi QinSeries Type : Expression profiling by high throughput sequencingOrganism : Penicillium oxalicumThe goals of this study are to compare different gene expressions for Penicillium oxalicum wild type strain (WT) and Hap3/5 deletion strain (Dhap3/5) under conditions of 2% glucose and 1% bran + 1% microcrystalline cellulose as ca […]
- GSE318779 The VgrG2 effector of Acinetobacter baumannii mediates immune evasion by repressing Csu pilus assembly and triggering phagocyte methuosis February 12, 2026Contributors : Wenzeng Xu ; Hua ZhouSeries Type : Expression profiling by high throughput sequencingOrganism : Acinetobacter baumanniiAcinetobacter baumannii is a formidable nosocomial pathogen whose multidrug resistance and immune evasion capabilities present a major therapeutic challenge. This study identifies the type VI secretion system (T6SS) effector V […]
- GSE318886 ALDH18A1 Promotes Gastric Cancer Progression and Regulates the PI3K-Akt Signaling Pathway February 12, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo elucidate the mechanism of ALDH18A1-driven gastric carcinogenesis and identify its downstream transcriptional targets, we conducted genome-wide RNA sequencing in HGC-27 cells knockdowning ALDH18A1, with comparison to negative control (si-NC) group.
- GSE318896 CUT&Tag profiling of Irx3 binding sites in AC16 cardiomyocytes supporting studies on cardiac regulatory mechanisms February 12, 2026Contributor : Li BingSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensThis study performed CUT&Tag sequencing to identify genome-wide binding sites of Irx3 in AC16 cardiomyocytes, aiming to reveal the regulatory role of Irx3 in cardiac biology.
- GSE318936 Physical Activity attenuates Sperm DNA Damage induced by Sedentary Behavior via Testicular Thermoregulation February 12, 2026Contributors : Xi Wen ; Xingcheng Yang ; Jiahui Wang ; Menghan Chen ; Linxiang Han ; Ying ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe contribution of male factors to infertility has been increasing progressively, with growing attention to non-genetic factors (lifestyle, environment). As a prevalent suboptim […]
- GSE294341 Transcriptomes of endothelial cells from mesenteric adipose tissue from wildtype and Myct1ecKO mice February 12, 2026Contributors : Anna Köck ; Amélie Sabine ; Tania Wyss ; Tatiana V PetrovaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSingle cell RNA sequencing of mesenteric adipose endothelial cells from adult willdtype and Myct1ecKO mice
- GSE317960 Liver RNA-seq from hepatocyte Tet1-overexpression MASH mice February 12, 2026Contributors : Fengyi Wang ; Tianshu Gao ; Junjie YuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo determine the mechanism underlying hepatocyte Tet1 regulated fibrogenesis in MASH liver, we performed RNA sequencing of liver samples from hepatocyte-specific Tet1-overexpression MASH mice. Differentially expressed gen […]