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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE294149 The immune NIK1/RPL10/LIMYB signaling module regulates photosynthesis and translation under biotic and abiotic stresses April 10, 2025Contributors : Marco Aurélio Ferreira ; Ruan Teixeira ; Otávio Brustolini ; Thainá Saia ; James Jean-Baptiste ; Nathalia Ribeiro ; Sâmera Breves ; Fellipe Sampaio ; Eulálio Santos ; Borys Leon ; Celio Oliveira ; Christiane Duarte ; Lucas Lima ; Leandro Oliveira ; Humberto Ramos ; Pedro Reis ; Elizabeth FontesSeries Type : Expression profiling by high through […]
- GSE217892 Intratumoral heterogeneity of glioblastoma is attributed to precancerous cells derived from neural stem cells April 10, 2025Contributors : Jeong Ho Lee ; Hyun Jung KimSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiens ; Mus musculusNeural stem cells (NSCs) in the subventricular zone (SVZ) have been identified as cells-of-origin carrying driver mutations in glioblastoma (GBM), but there is a lack of understanding how a few NSCs with driver muta […]
- GSE202805 Global Transcriptomic analysis of PBMC derived from COVID-19 acute-severe patients and convalescents April 10, 2025Contributors : Amit Singhal ; Dilip KumarSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensThe majority of patients with COVID-19 have a self-limiting upper respiratory tract infection mostly represented by asymptomatic or mild, however a small but relevant proportion of patients develops acute respiratory distress syndro […]
- GSE248820 EIF3D Safeguards the Homeostasis of Key Signaling Pathways in Human Primed Pluripotency April 10, 2025Series Type : Other ; Expression profiling by high throughput sequencingOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
- GSE248702 EIF3D Safeguards the Homeostasis of Key Signaling Pathways in Human Primed Pluripotency [RNA-Seq] April 10, 2025Contributors : Chikako Okubo ; Michiko Nakamura ; Kazutoshi TakahashiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensPluripotent stem cell identities such as differentiation and infinite proliferation have long been decoded in the frameworks of transcription factor networks, epigenomes, and signal transduction, yet uncl […]
- GSE263765 Dicer deficient adult microglia negatively impacts the process of demyelination and remyelination April 10, 2025Contributors : Ranjan Dutta ; Ajai Tripathi ; Nagendra K Rai ; Aaron Perles ; Haley Courtney ; Claire Jones ; Adya Sapra ; Jason PlemelSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMicroglia, the resident immune cells of the central nervous system (CNS), are important regulators of normal brain activities. In CNS demy […]
- GSE249191 EIF3D Safeguards the Homeostasis of Key Signaling Pathways in Human Primed Pluripotency [Ribo-seq] April 10, 2025Contributors : Chikako Okubo ; Michiko Nakamura ; Kazutoshi TakahashiSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Homo sapiensPluripotent stem cell identities such as differentiation and infinite proliferation have long been decoded in the frameworks of transcription factor networks, epigenomes, and signal transduction, […]
- GSE293870 Nuclear Receptor-SINE B1 Network Modulates Expanded Pluripotency in Blastoids and Blastocysts [RNA-seq 2] April 10, 2025Contributors : Ka Wai Wong ; Yingying Zeng ; Kiyofumi Hamashima ; Hu Li ; Yuin-Han LohSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusEmbryonic stem cells possess the remarkable ability to self-organize into blastocyst-like structures upon induction. These synthetic embryo models serve as invaluable platforms for studyi […]
- GSE293869 Nuclear Receptor-SINE B1 Network Modulates Expanded Pluripotency in Blastoids and Blastocysts [RNA-seq 1] April 10, 2025Contributors : Ka Wai Wong ; Yingying Zeng ; Kiyofumi Hamashima ; Hu Li ; Yuin-Han LohSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusEmbryonic stem cells possess the remarkable ability to self-organize into blastocyst-like structures upon induction. These synthetic embryo models serve as invaluable platforms for studyi […]
- GSE293910 Identification of fibroblast-derived sFRP2 as a new therapeutic target and engineering of siRNA therapies for uterine scarring April 10, 2025Contributor : Siqi ZhangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiens ; Mus musculusUterine scarring (US) is a common complication following uterine injury, characterized by abnormal wound healing in the endometrial or myometrial tissue. However, the underlying mechanisms contributing to scar formation remain unclear […]
- GSE293909 Platelet-Rich Fibrin Potentiates Dental Pulp Stem Cell Angiogenesis through Mitochondrial Transfer-Meditated Metabolic-Signaling Integration April 10, 2025Contributors : Jing Zhou ; Yihan Wang ; Xiuyu Liu ; Huixin Lv ; Yanmin ZhouSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTherapeutic angiogenesis in inflammatory microenvironments is constrained by mitochondrial dysfunction in mesenchymal stem cells (MSCs). This study demonstrates that platelet-rich fibrin (PRF) serve […]
- GSE293979 RNA-seq of Drosophila melanogaster wing imaginal discs during L3 stage April 10, 2025Contributors : Fanny Chazal ; Cédric MaurangeSeries Type : Expression profiling by high throughput sequencingOrganism : Drosophila melanogasterDuring the last larval stage (L3) of Drosophila melanosgaster development, wing imaginal discs undergo tremendous growth and initiate differentiation programs. This transcriptomic time course aims at uncovering the th […]
- GSE294032 Nuclear receptor-SINE B1 network modulates expanded pluripotency in blastoids and blastocysts. April 10, 2025Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencing ; Methylation profiling by high throughput sequencingOrganism : Mus musculusThis SuperSeries is composed of the SubSeries listed below.
- GSE294101 RNA-seq profile of Sam-S overexpressed female Drosophila germline. April 10, 2025Contributors : Yoshiki Hayashi ; Shinjiro Hino ; Tetsuya Sato ; Ban Sato ; Natsuko Kawano ; Mitsuyoshi Nakao ; Mikita SuyamaSeries Type : Expression profiling by high throughput sequencingOrganism : Drosophila melanogasterS-adenosylmethionine (SAM) is the principal cellular donor of methyl-moiety in methylation reaction and regulates gene expression by regul […]
- GSE278880 Isocitrate Dehydrogenase 1 Primes Group-3 Medulloblastomas For Cuproptosis April 10, 2025Contributor : Sriram VennetiSeries Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensMYC-driven Group-3 medulloblastomas (MB) are malignant pediatric brain cancers without cures. To define actionable metabolic dependencies, we identified upregulationof dihydrolip […]