NCBI Insights

NCBI Insights

• Changes to SRA Data Access on Amazon Web Services (AWS) September 11, 2024
  Cost-effective alternatives for accessing SRA data   Important note! The storage tier for Sequence Read Archive (SRA) data available through Amazon Web Services (AWS) commercial buckets is transitioning to Infrequent Access. This change is projected to be complete by the end of September 2024. To mitigate the cost impact of this change, we recommend adjustin […]
  NCBI Staff
• Coming Soon! Improving Representation of Functional Data in ClinVar September 10, 2024
  NCBI is improving the way that functional data are submitted to ClinVar and how they are represented in the XML format and on the website. Almost half of the variants in ClinVar are variants of uncertain significance (VUS). It’s unclear what clinical action to take for these variants, creating a challenge for clinicians. One potential … Continue reading Comi […]
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• Submitting High-Throughput Sequence Data to Gene Expression Omnibus (GEO) September 4, 2024
  Submit your transcriptomic and epigenomic data to Gene Expression Omnibus (GEO)! GEO is a public functional genomics data repository that relies on your data submissions. We are pleased to announce a new submission interface to improve your experience.   What’s new?  A web interface for uploading your GEO metadata   Metadata immediately validated for format […]
  NCBI Staff
• New Milestone! NCBI Pathogen Detection Reaches 2 Million Isolates September 3, 2024
  NCBI’s Pathogen Detection resource collects, analyzes, and reports on bacterial and fungal isolate genome sequences for outbreak identification and tracking. Pathogen Detection is also central to the surveillance of anti-microbial resistance, virulence, and stress resistance for 97 pathogenic taxa covering 753 species, and now includes analysis results for o […]
  NCBI Staff
• NCBI Taxonomy Updates to Yeasts August 29, 2024
  As previously announced, NCBI is continually making improvements to our Taxonomy resource in response to new data and changes in biological nomenclature. We recently made classification changes to budding yeasts and allies (Saccharomycotina), which consists of more than 1,200 species and exhibits levels of genomic diversity similar to those of plants and ani […]
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• Now Available: GenBank Release 262.0! August 26, 2024
  GenBank release 262.0 (8/22/2024) is now available on the NCBI FTP site. This release has 34.10 trillion bases and 4.76 billion records. The current release has:  251,998,350 traditional records containing 3,675,462,701,077 base pairs of sequence data 3,569,715,357 WGS records containing 29,643,594,176,326 base pairs of sequence data 755,907,377 bulk-oriente […]
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• NCBI Hidden Markov Models (HMM) Release 16.0 Now Available! August 22, 2024
  Download release 16.0 of the NCBI protein profile Hidden Markov models (HMMs) used by the Prokaryotic Genome Annotation Pipeline (PGAP)! Search this collection against your favorite prokaryotic proteins to identify their function using the HMMER sequence analysis package. What’s New? Release 16.0 contains: 17,078 HMMs maintained by NCBI 406 new HMMs since re […]
  NCBI Staff
• Quick & Easy Access to Mpox Data Through NCBI Virus August 21, 2024
  The World Health Organization (WHO) declared the recent upsurge of the mpox virus to be a public health emergency of international concern. Having timely viral genome data freely and widely available enables researchers to explore how this virus differs from viruses isolated and sequenced in the past. Therefore, NCBI’s GenBank is expediting the release of mp […]
  NCBI Staff
• NCBI’s First-Ever BioEd Summit Was a Success! August 19, 2024
  NCBI hosted its first-ever BioEd Summit: Crafting Student-Centric Curricula with NCBI resources. This week-long, in-person event for science educators across the U.S. was held on the National Institutes of Health (NIH) campus in Bethesda, MD, from August 5-9, 2024.  Event Details  During the week, educators participated in morning sessions including interact […]
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• NCBI’s PopSet Database to Retire Effective January 2025 August 14, 2024
  Beginning in January 2025, NCBI’s PopSet database will no longer be available. While PopSet web pages (example) will no longer be accessible, individual sequences of PopSet will still be searchable and accessible in Nucleotide as independent records (example).  A link under ‘Related information’ on a GenBank record page will also let users access other seque […]
  NCBI Staff