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Gene Expression Omnibus Announcements & Study Releases
Announcements of updates and changes to the Gene Expression Omnibus (GEO) databases and notifications of newly released functional genomic studies.
- GSE266014 BV-2 Cells: Control vs.OGD/R April 1, 2026Contributor : Qian SuSeries Type : Expression profiling by arrayOrganism : Mus musculusThe difference of the m6A modification of tsRNAs of microglia after OGD/R . Goal was to reveal the m6A modification of tsRNAs and study the possible role of these RNAs in ischaemic microglia.
- GSE229859 mRNA sequencing in mouse trophoblast stem cells (mTSCs) with and without knockdown of METTL3 April 1, 2026Contributor : J DongSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo determine the expression of mRNAs after knockdown of METTL3, we performed RNA-Seq in mTSCs with or without knockdown of METTL3.
- GSE292237 H2AK119ub1 counteracts MLL2 functions to direct heritable H3K27me3 formation in mouse oocytes April 1, 2026Contributors : Hailiang Mei ; Chisayo Kozuka ; Mami Kumon ; Haruhiko Koseki ; Azusa InoueSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusPolycomb group (PcG) and Trithorax group (TrxG) family proteins form repressive and permissive states of chromatin, respectively, to regulate developmental genes. They counteract with […]
- GSE283439 RNA sequencing of neutrophils treated with microvesicles derived from glucose-deprived hepatocellular carcinoma cells. April 1, 2026Contributors : Yuge Ji ; Deyi FengSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusMicrovesicles derived from glucose-deprived liver cancer cells can promote tumor initiation and progression through neutrophils. This phenomenon can be rescued by knocking down Ezrin. Comparative analysis revealed that microvesicles from E […]
- GSE295590 Non-redundant roles for ILC2 and TH2 cells during anamnestic lung Type 2 immunity April 1, 2026Contributors : Ulrich Membe Femoe ; De’Broski R HerbertSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusType 2 immune responses help with wound healing and clearing helminth infections, but the distinct roles of group 2 innate lymphoid cells (ILC2s) and T-helper 2 (TH2) cells are not fully understood. In this study, we e […]
- GSE294052 Deciphering the STAT3-PXN positive feedback loop in GBM, IDH-wildtype: transcriptional regulation and inhibition of YB-1 ubiquitination April 1, 2026Series Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensY-box binding protein 1 (YB-1) has been implicated in the progression of glioblastoma (GBM), a highly aggressive brain tumor. This study investigated the transcriptional regulatory role of YB-1 in GBM through the deployment of mRNA sequencing (RNA-seq) on U87 and U373 glio […]
- GSE326611 mRNA m6A modifications and the RNA-binding protein YTHDF1 affect translational control in both normal and pathological learning April 1, 2026Contributors : Zhuoyue Shi ; Zhongyu ZouSeries Type : OtherOrganism : Mus musculusAnimals learn and adapt to environmental changes. However, neural plasticity can also become maladaptive, leading to neurological and psychiatric disorders. How do we use known molecular mechanisms to harness the power of neural plasticity to prevent and treat diseases? Consoli […]
- GSE300966 Functional Requirement for Arginine Methylation of the Dicer Helicase Domain in 26G Endo-siRNA Pathway Activity and the Oocyte Meiotic Program April 1, 2026Contributors : Nick Newkirk ; Shin-Yu Chen ; Tokiko Furuta ; Leilei Shi ; Sabrina Stratton ; Hongyuan Lin ; Xiaodong Cheng ; Mark Bedford ; Swathi ArurSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Caenorhabditis elegansSpatiotemporal regulation of Dicer is critical for small RNA biogenesis, fertility, and early embryogenesis, […]
- GSE326651 in vivo human embryonic spinal cord atlas validates stem cell-derived human dorsal interneurons and reveals ASD spinal signatures [day0NMP_bulk RNAseq] April 1, 2026Contributors : Sandeep Gupta ; Eric Heinrichs ; Cristian Rodriguez ; Emily Friedman ; Salena Gallardo ; Talin Dermirjie ; Teny Panosian ; Keith Phan ; Anooshik Tahmasian ; Yahir Veridin ; Samantha J ButlerSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensSpinal cord injuries (SCI) result in the loss of motor and sensory f […]
- GSE326623 inDropsPilot_29hpf-ef1a-mCherry April 1, 2026Contributors : Aponte-Santiago Nicole ; Wagner DanSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioWe profiled gene expression during zebrafish development. This inDrops single-cell RNA-seq dataset comprises 12,603 cells collected from 29 hpf Danio rerio embryos. Here, nuclear-tagged mCherry2 is driven by a ~2.2 kb upstre […]
- GSE326652 in vivo human embryonic spinal cord atlas validates stem cell-derived human dorsal interneurons and reveals ASD spinal signatures [day0NMP_scRNAseq] April 1, 2026Contributors : Sandeep Gupta ; Eric Heinrichs ; Cristian Rodriguez ; Emily Friedman ; Salena Gallardo ; Talin Dermirjie ; Teny Panosian ; Keith Phan ; Anooshik Tahmasian ; Yahir Veridin ; Samantha J ButlerSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensSpinal cord injuries (SCI) result in the loss of motor and sensory f […]
- GSE326654 in vivo human embryonic spinal cord atlas validates stem cell-derived human dorsal interneurons and reveals ASD spinal signatures [day27NMP_scRNAseq] April 1, 2026Contributors : Sandeep Gupta ; Eric Heinrichs ; Cristian Rodriguez ; Emily Friedman ; Salena Gallardo ; Talin Dermirjie ; Teny Panosian ; Keith Phan ; Anooshik Tahmasian ; Yahir Veridin ; Samantha J ButlerSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensSpinal cord injuries (SCI) result in the loss of motor and sensory f […]
- GSE326655 in vivo human embryonic spinal cord atlas validates stem cell-derived human dorsal interneurons and reveals ASD spinal signatures [day43NMP_scRNAseq] April 1, 2026Contributors : Sandeep Gupta ; Eric Heinrichs ; Cristian Rodriguez ; Emily Friedman ; Salena Gallardo ; Talin Dermirjie ; Teny Panosian ; Keith Phan ; Anooshik Tahmasian ; Yahir Veridin ; Samantha J ButlerSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensSpinal cord injuries (SCI) result in the loss of motor and sensory f […]
- GSE305225 Plant-specific function of H3K9me3 as a permissive chromatin mark during Arabidopsis seed germination April 1, 2026Contributors : Jae-Wook Yoon ; Min-Jeong Kang ; Hongshi Jin ; Yoo-Sun Noh ; Bosl NohSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Arabidopsis thalianaSeed dormancy and germination are sequential phases, both tightly regulated by environmental and hormonal cues to ensure germination under favorable conditions. While […]
- GSE326526 Ethylene glycol poisoning induces nephrolithiasis including complement-fibrinogen-related renal tubular injury in rats April 1, 2026Contributors : Toshihiko Aki ; Kana Unuma ; Shintaro Isa ; Kanako Noritake ; Atsushi Yamada ; Akihiro TojoSeries Type : Expression profiling by arrayOrganism : Rattus norvegicusWe conducted transcriptome analysis to search clues to find novel mechanisms during ethylene glycol intoxication (8 g/kg body weight, orally, 2 and 5 days) in rat kidney.Total RNAs fr […]